Page last updated: 2024-08-21

plumbagin and Cancer of Liver

plumbagin has been researched along with Cancer of Liver in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (72.73)24.3611
2020's3 (27.27)2.80

Authors

AuthorsStudies
Bi, S; Chu, D; Guo, J; Guo, T; Han, S; Liao, A; Song, L; Song, X; Sun, D; Wang, L; Yu, Z; Zou, Y1
Chen, X; Huang, Q; Jiang, B; Liu, J; Qi, L; Tang, D; Xue, Q; Yan, D; Yao, L1
Jin, L; Liang, L; Liu, H; Liu, S; Wei, Y; Zhang, W1
Chen, Y; Lin, Y; Lv, B; Ma, J; Peng, Y; Wang, S; Wei, Y; Xie, J; Zhang, Y; Zhong, J1
Chen, W; Huang, D; Huo, L; Li, J; Lin, Y; Wei, J; Wei, Y; Zhao, C; Zhong, J1
Chen, A; Jiang, Z; Liu, D; Liu, M; Lu, J; Wang, X; Ye, X; Zhou, X1
Chen, W; Chen, Y; Lin, Y; Lv, B; Ma, J; Peng, Y; Wang, S; Wei, Y; Yuan, X1
Li, R; Su, M; Wu, K; Zhou, R1
Itharat, A; Pawa, KK; Rattarom, R; Ruangnoo, S; Sakpakdeejaroen, I; Tappayutpijam, P1
Chen, Y; Li, J; Liu, X; Ma, J; Wei, Y; Yang, Q; Zhang, Y; Zhao, C; Zhao, T; Zhong, J1
Chen, ZF; Liang, H; Liu, HG; Liu, YC; Peng, Y; Tan, MX; Wang, HH1

Other Studies

11 other study(ies) available for plumbagin and Cancer of Liver

ArticleYear
Nano co-delivery of Plumbagin and Dihydrotanshinone I reverses immunosuppressive TME of liver cancer.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 348

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Furans; Lactic Acid; Liver Neoplasms; Mice; Nanoparticles; Naphthoquinones; Phenanthrenes; Quinones; Tumor Microenvironment

2022
Plumbagin is a novel GPX4 protein degrader that induces apoptosis in hepatocellular carcinoma cells.
    Free radical biology & medicine, 2023, Volume: 203

    Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Liver Neoplasms; Mitochondrial Proteins; Thiolester Hydrolases; Ubiquitin Thiolesterase; Ubiquitin-Specific Proteases

2023
Plumbagin Exhibits Genotoxicity and Induces G2/M Cell Cycle Arrest via ROS-Mediated Oxidative Stress and Activation of ATM-p53 Signaling Pathway in Hepatocellular Cells.
    International journal of molecular sciences, 2023, Mar-27, Volume: 24, Issue:7

    Topics: Ataxia Telangiectasia Mutated Proteins; Carcinoma, Hepatocellular; Cell Cycle Proteins; Checkpoint Kinase 2; DNA Damage; Humans; Liver Neoplasms; M Cells; Naphthoquinones; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; Signal Transduction; Tumor Suppressor Protein p53

2023
Plumbagin promotes human hepatoma SMMC-7721 cell apoptosis via caspase-3/vimentin signal-mediated EMT.
    Drug design, development and therapy, 2019, Volume: 13

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Cell Line, Tumor; Cell Proliferation; Epithelial-Mesenchymal Transition; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Naphthoquinones; Signal Transduction; Vimentin

2019
Plumbagin Restrains Hepatocellular Carcinoma Angiogenesis by Stromal Cell-Derived Factor (SDF-1)/CXCR4-CXCR7 Axis.
    Medical science monitor : international medical journal of experimental and clinical research, 2019, Aug-15, Volume: 25

    Topics: Angiogenesis Inhibitors; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chemokine CXCL12; Human Umbilical Vein Endothelial Cells; Humans; Interleukin-8; Liver; Liver Neoplasms; Naphthoquinones; Neoplasm Invasiveness; Neovascularization, Pathologic; Receptors, CXCR; Receptors, CXCR4; Signal Transduction; Stromal Cells; Vascular Endothelial Growth Factor A

2019
Plant natural product plumbagin presents potent inhibitory effect on human cytochrome P450 2J2 enzyme.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2018, Jan-15, Volume: 39

    Topics: Animals; Antineoplastic Agents; Biological Products; Carcinoma, Hepatocellular; Cell Proliferation; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Evaluation, Preclinical; Hepatocytes; Humans; Kinetics; Liver Neoplasms; Male; Microsomes, Liver; Molecular Docking Simulation; Naphthoquinones; Rats, Sprague-Dawley

2018
Plumbagin induces autophagy and apoptosis of SMMC-7721 cells in vitro and in vivo.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:6

    Topics: Animals; Apoptosis; Autophagic Cell Death; Carcinoma, Hepatocellular; Cell Line, Tumor; Female; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Naphthoquinones; Xenograft Model Antitumor Assays

2019
Bioinformatic and experimental data decipher the pharmacological targets and mechanisms of plumbagin against hepatocellular carcinoma.
    Environmental toxicology and pharmacology, 2019, Volume: 70

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Computational Biology; Cyclin D1; Female; Hep G2 Cells; Humans; Liver Neoplasms; Male; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Naphthoquinones; Proto-Oncogene Proteins c-raf; Tumor Suppressor Protein p53

2019
In vitro cytotoxic activity of Benjakul herbal preparation and its active compounds against human lung, cervical and liver cancer cells.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2012, Volume: 95 Suppl 1

    Topics: Alkaloids; Benzodioxoles; Catechols; Cell Line, Tumor; Fatty Alcohols; Female; Humans; Liver Neoplasms; Lung Neoplasms; Medicine, East Asian Traditional; Naphthoquinones; Phytotherapy; Piper; Piperidines; Plant Extracts; Plants, Medicinal; Plumbaginaceae; Polyunsaturated Alkamides; Thailand; Uterine Cervical Neoplasms; Zingiber officinale

2012
Plumbagin restrains hepatocellular carcinoma angiogenesis by suppressing the migration and invasion of tumor-derived vascular endothelial cells.
    Oncotarget, 2017, Feb-28, Volume: 8, Issue:9

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Endothelial Cells; Female; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Naphthoquinones; Neoplasm Invasiveness; Neovascularization, Pathologic; Signal Transduction; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2017
Synthesis, characterization and preliminary cytotoxicity evaluation of five lanthanide(III)-plumbagin complexes.
    Journal of inorganic biochemistry, 2011, Volume: 105, Issue:3

    Topics: Antineoplastic Agents; Cations; Cell Line, Tumor; DNA; Humans; Inhibitory Concentration 50; Lanthanoid Series Elements; Liver Neoplasms; Naphthoquinones; Organometallic Compounds; Pilot Projects; Spectrum Analysis; Thermogravimetry

2011