plerixafor has been researched along with Invasiveness, Neoplasm in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (22.86) | 29.6817 |
| 2010's | 25 (71.43) | 24.3611 |
| 2020's | 2 (5.71) | 2.80 |
| Authors | Studies |
|---|---|
| Kurtkaya, S; Liang, Z; Liotta, DC; Shim, H; Snyder, JP; Zhan, W; Zhu, A | 1 |
| Cavallini, C; Cerofolini, L; D'Amore, VM; Daniele, S; Fragai, M; Giuntini, S; La Pietra, V; La Regina, G; Luchinat, C; Marinelli, L; Martini, C; Nalli, M; Novellino, E; Pedrini, M; Piccarducci, R; Pietrobono, D; Puxeddu, M; Russomanno, P; Silvestri, R; Taliani, S | 1 |
| Bian, W; Liu, JH; Liu, SG; Lv, HT; Wang, WB; Xing, L; Zhang, TF | 1 |
| Han, Y; Liu, N; Wang, J; Wu, C | 1 |
| Dizdar, L; Forster, CM; Knoefel, WT; Krieg, A; Raba, K; Schott, M; Verde, PE; Werner, TA | 1 |
| Huang, Y; Lu, H; Sheng, X; Xia, R; Xu, G; Xu, X | 1 |
| Folarin, N; Gaken, J; Hersi, HM; Raulf, N; Tavassoli, M | 1 |
| Chen, YN; Liu, Y; Ren, CC; Xu, YM; Yang, L | 1 |
| Chen, J; Gao, Y; Jia, L; Li, B; Liu, J; Liu, W; Shao, J; Wang, J; Zheng, N | 1 |
| Zhao, ZF; Zhou, X; Zhu, WB | 1 |
| Gao, G; Jiang, Z; Li, X; Xu, Y; Zhou, W | 1 |
| Li, J; Oupický, D; Wang, Y | 1 |
| Dedobbeleer, M; Denne, A; Di Valentin, E; Goffart, N; Kroonen, J; Martinive, P; Rogister, B | 1 |
| Ahn, SH; An, SY; Choi, IJ; Jeon, EH; Jeong, WJ; Paik, JH; Park, MW; Sung, MW | 1 |
| Alcoceba, M; Blanco, O; Bosch, R; Casanova, I; Céspedes, MV; Dieguez-Gonzalez, R; Gallardo, A; Gonzalez-Díaz, M; Grañena, A; Mangues, R; Moreno, MJ; Mozos, A; Novelli, S; Pavón, MÁ; Sierra, J | 1 |
| Foltz, G; Harrison, JK; Hothi, P; Law, BK; Luo, D; Pham, K; Reynolds, BA; Siemann, DW | 1 |
| Chen, A; Munshi, A; Muralidharan, R; Panneerselvam, J; Ramesh, R; Zhao, YD | 1 |
| Li, J; Mott, JL; Oupický, D; Wang, Y; Wehrkamp, CJ; Xie, Y | 1 |
| Bian, XW; Cui, W; Cui, YH; Guo, ZJ; Ji, CD; Qian, F; Wang, JM; Wang, YX; Xiang, DF; Yang, L; Yu, X; Zhang, P; Zhang, X | 1 |
| An, F; Fang, S; Jin, D; Kong, J; Li, J; Li, X; Lin, B; Liu, L; Liu, T; Luo, Y; Yang, X; Zhang, W | 1 |
| Guo, JC; Li, J; Liang, ZY; Yang, JY; You, L; Zhang, TP; Zhang, ZG; Zhao, YP; Zhou, L; Zhou, WX | 1 |
| Bieche, I; Kieffer, Y; Lefort, S; Marangoni, E; Mechta-Grigoriou, F; Sirven, P; Thuleau, A; Vincent-Salomon, A | 1 |
| Bian, Z; Fang, X; Jiang, C; Jiang, W; Li, M; Tian, F; Wang, X; Zhang, H; Zhu, L | 1 |
| Baleux, F; Brule, S; Charnaux, N; Friand, V; Gattegno, L; Sutton, A | 1 |
| Huang, SM; Jeon, SB; Kim, JM; Kim, SJ; Koh, SS; Lee, Y; Lim, DS; Park, EH; Park, HD | 1 |
| Cronin, PA; Redmond, HP; Wang, JH | 1 |
| Allgayer, H; Eckstein, V; Fruehauf, S; Giordano, FA; Heckmann, D; Laufs, S; Maier, P; Veldwijk, MR; Wenz, F; Zeller, WJ; Zucknick, M | 1 |
| Chen, Y; Feng, GS; Fu, J; He, YQ; Li, YQ; Li, Z; Lin, Y; Liu, Q; Tang, L; Wang, C; Wang, HY; Wu, FQ; Wu, MC; Yan, HX; Yang, W; Yu, LX; Zhang, HL; Zheng, LY; Zou, SS | 1 |
| Fang, D; Lin, S; Su, N; Sun, L; Yu, B; Yuan, S; Zhou, L | 1 |
| Balkwill, FR; Bridger, G; Fricker, S; Scott, K; Scotton, CJ; Stamp, G; Wilbanks, GD; Wilson, JL | 1 |
| Sarkar, S; Yong, VW; Zhang, J | 1 |
| Harada, K; Ishikawa, A; Isse, K; Kozaka, K; Nakanuma, Y; Nimura, Y; Oda, K; Ohira, S; Sasaki, M; Sato, Y; Zen, Y | 1 |
| Hongeng, S; Leelawat, K; Leelawat, S; Narong, S | 1 |
| Bergers, G; Du, R; Ganss, R; Johnson, RS; Liu, P; Lu, KV; Passegué, E; Petritsch, C; Song, H; Vandenberg, S; Werb, Z | 1 |
| Li, JK; Shen, Y; Wang, YC; Yu, L; Zhang, JH; Zhou, LS | 1 |
35 other study(ies) available for plerixafor and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Discovery of small molecule CXCR4 antagonists.
Topics: Aminopyridines; Antineoplastic Agents; Benzylamines; Binding, Competitive; Cell Line, Tumor; Chemokine CXCL12; Collagen; Cyclic AMP; Drug Combinations; Fluorescence Resonance Energy Transfer; Humans; Laminin; Models, Molecular; Neoplasm Invasiveness; Proteoglycans; Quantitative Structure-Activity Relationship; Receptors, CXCR4; Stereoisomerism | 2007 |
CXCR4 antagonism sensitizes cancer cells to novel indole-based MDM2/4 inhibitors in glioblastoma multiforme.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzylamines; Brain Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclams; Drug Synergism; Glioblastoma; Humans; Indoles; Neoplasm Invasiveness; Neoplastic Stem Cells; Neurogenesis; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Receptors, CXCR4; Signal Transduction; Spheroids, Cellular; Tumor Suppressor Protein p53 | 2021 |
The effect of gemcitabine combined with AMD3100 applying to cholangiocarcinoma RBE cell lines to CXCR4/CXCL12 axis.
Topics: Benzylamines; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chemokine CXCL12; Cholangiocarcinoma; Cyclams; Deoxycytidine; Gemcitabine; Humans; Neoplasm Invasiveness; Receptors, CXCR4 | 2021 |
CXCR7 maintains osteosarcoma invasion after CXCR4 suppression in bone marrow microenvironment.
Topics: Benzylamines; Bone Marrow Cells; Cell Line, Tumor; Cell Proliferation; Coculture Techniques; Cyclams; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds; Humans; Mesenchymal Stem Cells; Neoplasm Invasiveness; Neoplasm Metastasis; Osteosarcoma; Receptors, CXCR; Receptors, CXCR4; Tumor Microenvironment | 2017 |
CXCR4/CXCR7/CXCL12 axis promotes an invasive phenotype in medullary thyroid carcinoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminopyridines; Antigens, CD; Benzylamines; Cadherins; Carcinoma, Neuroendocrine; Cell Cycle; Cell Line, Tumor; Chemokine CXCL12; Child; Cyclams; Epithelial-Mesenchymal Transition; Female; Fibroblast Growth Factor 9; Gene Expression; GPI-Linked Proteins; Heterocyclic Compounds; Humans; Immunohistochemistry; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Phenotype; Prognosis; Receptors, CXCR; Receptors, CXCR4; Recombinant Proteins; Retrospective Studies; Snail Family Transcription Factors; Survival Rate; Thyroid Neoplasms; Tissue Array Analysis; Tumor Burden; Vimentin; Young Adult | 2017 |
Hesperidin suppresses the migration and invasion of non-small cell lung cancer cells by inhibiting the SDF-1/CXCR-4 pathway.
Topics: A549 Cells; Antineoplastic Agents, Phytogenic; Benzylamines; Carcinoma, Non-Small-Cell Lung; Cell Movement; Chemokine CXCL12; Chemotaxis; Cyclams; Dose-Response Relationship, Drug; Hesperidin; Heterocyclic Compounds; Humans; Lung Neoplasms; Neoplasm Invasiveness; Neoplasm Proteins; Receptors, CXCR4; Signal Transduction; Wound Healing | 2018 |
MicroRNA-9 inhibits growth and invasion of head and neck cancer cells and is a predictive biomarker of response to plerixafor, an inhibitor of its target CXCR4.
Topics: Antineoplastic Agents; Benzylamines; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclams; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Heterocyclic Compounds; Humans; MicroRNAs; Neoplasm Invasiveness; Prognosis; Receptors, CXCR4; Treatment Outcome | 2018 |
Role of CXCL12-CXCR4 axis in ovarian cancer metastasis and CXCL12-CXCR4 blockade with AMD3100 suppresses tumor cell migration and invasion in vitro.
Topics: Adult; Aged; Antineoplastic Agents; Apoptosis; Benzylamines; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chemokine CXCL12; Cyclams; Female; Heterocyclic Compounds; Humans; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Ovarian Neoplasms; Receptors, CXCR4; Signal Transduction | 2019 |
CXCR7 is not obligatory for CXCL12-CXCR4-induced epithelial-mesenchymal transition in human ovarian cancer.
Topics: Animals; Apoptosis; Benzylamines; Biomarkers, Tumor; Cell Movement; Cell Proliferation; Chemokine CXCL12; Cyclams; Epithelial-Mesenchymal Transition; Female; Heterocyclic Compounds; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Ovarian Neoplasms; Peritoneal Neoplasms; Receptors, CXCR; Receptors, CXCR4; Signal Transduction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2019 |
AMD3100 inhibits epithelial-mesenchymal transition, cell invasion, and metastasis in the liver and the lung through blocking the SDF-1α/CXCR4 signaling pathway in prostate cancer.
Topics: Animals; Benzylamines; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Shape; Cell Survival; Chemokine CXCL12; Cyclams; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds; Liver Neoplasms; Lung Neoplasms; Male; Mice, Nude; Neoplasm Invasiveness; Neoplasm Proteins; Phosphorylation; Prostatic Neoplasms; Receptors, CXCR4; RNA, Messenger; Signal Transduction | 2019 |
Irradiated normal brain promotes invasion of glioblastoma through vascular endothelial growth and stromal cell-derived factor 1α.
Topics: Animals; Benzylamines; Brain; Brain Chemistry; Brain Neoplasms; Chemokine CXCL12; Cyclams; Cytokines; Gamma Rays; Glioblastoma; Heterocyclic Compounds; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Real-Time Polymerase Chain Reaction; Receptors, CXCR4; Vascular Endothelial Growth Factor A | 2013 |
Polymeric Plerixafor: effect of PEGylation on CXCR4 antagonism, cancer cell invasion, and DNA transfection.
Topics: Benzylamines; Cell Line, Tumor; Chemistry, Pharmaceutical; Chromatography, Gel; Cyclams; DNA; Ethidium; Heterocyclic Compounds; Humans; Neoplasm Invasiveness; Pharmaceutical Vehicles; Polyethylene Glycols; Receptors, CXCR4; Transfection | 2014 |
Adult mouse subventricular zones stimulate glioblastoma stem cells specific invasion through CXCL12/CXCR4 signaling.
Topics: Animals; Benzylamines; Brain Neoplasms; Cell Line, Tumor; Chemokine CXCL12; Cyclams; Disease Models, Animal; Female; Glioblastoma; Heterocyclic Compounds; Humans; Lateral Ventricles; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplastic Stem Cells; Receptors, CXCR4; Signal Transduction | 2015 |
CXCR4 antagonist inhibits perineural invasion of adenoid cystic carcinoma.
Topics: Animals; Antineoplastic Agents; Benzylamines; Carcinoma, Adenoid Cystic; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclams; Female; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds; Humans; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Peripheral Nervous System; Receptors, CXCR4; RNA Interference; Salivary Gland Neoplasms; Time Factors; Transfection; Xenograft Model Antitumor Assays | 2014 |
CXCR4 expression enhances diffuse large B cell lymphoma dissemination and decreases patient survival.
Topics: Animals; Benzylamines; Cell Line, Tumor; Cell Movement; Cyclams; Disease Models, Animal; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds; Humans; In Vitro Techniques; Lymphoma, Large B-Cell, Diffuse; Male; Mice; Mice, Inbred NOD; Mice, SCID; Middle Aged; Neoplasm Invasiveness; Prognosis; Receptors, CXCR4; Survival Rate; Xenograft Model Antitumor Assays | 2015 |
VEGFR inhibitors upregulate CXCR4 in VEGF receptor-expressing glioblastoma in a TGFβR signaling-dependent manner.
Topics: Adult; Aged; Angiogenesis Inhibitors; Animals; Benzylamines; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cyclams; Female; Glioblastoma; Heterocyclic Compounds; Humans; Interleukin-2 Receptor alpha Subunit; Male; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Middle Aged; Neoplasm Invasiveness; Piperidines; Protein Kinase Inhibitors; Quinazolines; Receptor Cross-Talk; Receptors, CXCR4; Receptors, Transforming Growth Factor beta; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; Time Factors; Up-Regulation; Xenograft Model Antitumor Assays | 2015 |
HuR-targeted nanotherapy in combination with AMD3100 suppresses CXCR4 expression, cell growth, migration and invasion in lung cancer.
Topics: Antineoplastic Agents; Benzylamines; Cell Movement; Cell Proliferation; Combined Modality Therapy; Cyclams; Down-Regulation; ELAV-Like Protein 1; Heterocyclic Compounds; Humans; Lung Neoplasms; Nanoparticles; Neoplasm Invasiveness; Receptors, CXCR4; RNA, Small Interfering | 2015 |
Delivery of miR-200c Mimic with Poly(amido amine) CXCR4 Antagonists for Combined Inhibition of Cholangiocarcinoma Cell Invasiveness.
Topics: Apoptosis; Benzylamines; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Blotting, Western; Cell Movement; Cell Proliferation; Cholangiocarcinoma; Cyclams; Drug Delivery Systems; Drug Therapy, Combination; Heterocyclic Compounds; Humans; MicroRNAs; Neoplasm Invasiveness; Polyamines; Real-Time Polymerase Chain Reaction; Receptors, CXCR4; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2016 |
Transcription factor RUNX2 up-regulates chemokine receptor CXCR4 to promote invasive and metastatic potentials of human gastric cancer.
Topics: Animals; Apoptosis; Benzylamines; Biomarkers, Tumor; Cell Movement; Cell Proliferation; Core Binding Factor Alpha 1 Subunit; Cyclams; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds; Humans; Lymphatic Metastasis; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Prognosis; Receptors, CXCR4; Signal Transduction; Stomach Neoplasms; Survival Rate; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2016 |
A novel microfluidic model can mimic organ-specific metastasis of circulating tumor cells.
Topics: Animals; Antineoplastic Agents; Benzylamines; Breast Neoplasms; Cell Adhesion; Cell Movement; Chemokines; Coculture Techniques; Cyclams; Female; Heterocyclic Compounds; Human Umbilical Vein Endothelial Cells; Humans; Lab-On-A-Chip Devices; Lung Neoplasms; MCF-7 Cells; Mice, Inbred BALB C; Mice, Nude; Microfluidic Analytical Techniques; Neoplasm Invasiveness; Neoplastic Cells, Circulating; Organ Specificity; Primary Cell Culture; Rats, Sprague-Dawley; Salivary Gland Neoplasms; Time Factors | 2016 |
CXCL12-CXCR7 axis contributes to the invasive phenotype of pancreatic cancer.
Topics: Adult; Aged; Aged, 80 and over; Animals; Benzylamines; Cell Movement; Cell Proliferation; Chemokine CXCL12; Cyclams; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds; Humans; Male; Mice; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Transplantation; Pancreatic Neoplasms; Prognosis; Receptors, CXCR; Signal Transduction; TOR Serine-Threonine Kinases | 2016 |
CXCR4 inhibitors could benefit to HER2 but not to triple-negative breast cancer patients.
Topics: Animals; Anti-HIV Agents; Apoptosis; Benzylamines; Biomarkers, Tumor; Breast Neoplasms; Cell Proliferation; Cyclams; Female; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds; Humans; Lung Neoplasms; Mice; Neoplasm Invasiveness; Neovascularization, Pathologic; Peptides; Receptor, ErbB-2; Receptors, CXCR4; Signal Transduction; Triple Negative Breast Neoplasms; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2017 |
AMD3100 combined with triptolide inhibit proliferation, invasion and metastasis and induce apoptosis of human U2OS osteosarcoma cells.
Topics: Animals; Apoptosis; Benzylamines; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclams; Diterpenes; Down-Regulation; Epoxy Compounds; Female; Heterocyclic Compounds; Humans; Mice; Mice, Inbred C3H; Neoplasm Invasiveness; Neoplasm Metastasis; Osteosarcoma; Phenanthrenes; Signal Transduction | 2017 |
Glycosaminoglycans and syndecan-4 are involved in SDF-1/CXCL12-mediated invasion of human epitheloid carcinoma HeLa cells.
Topics: Anthracenes; Benzylamines; Carcinoma in Situ; Cell Movement; Chemokine CXCL12; Cyclams; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Glycosaminoglycans; HeLa Cells; Heterocyclic Compounds; Humans; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Signal Transduction; Syndecan-4; Uterine Cervical Neoplasms | 2009 |
PAUF functions in the metastasis of human pancreatic cancer cells and upregulates CXCR4 expression.
Topics: Animals; Benzylamines; Blotting, Western; Cell Line, Tumor; Cell Movement; Cyclams; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds; Humans; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Lectins; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms, Experimental; Oligonucleotide Array Sequence Analysis; Pancreatic Neoplasms; Receptors, CXCR4; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transplantation, Heterologous; Up-Regulation | 2010 |
Hypoxia increases the metastatic ability of breast cancer cells via upregulation of CXCR4.
Topics: Animals; Antibodies, Monoclonal; Benzylamines; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Membrane; Chemokine CXCL12; Chemotaxis; Cyclams; Female; Flow Cytometry; Heterocyclic Compounds; Humans; Mice; Neoplasm Invasiveness; Receptors, CXCR4; Recombinant Proteins; Time Factors; Up-Regulation | 2010 |
A Lentiviral CXCR4 overexpression and knockdown model in colorectal cancer cell lines reveals plerixafor-dependent suppression of SDF-1α-induced migration and invasion.
Topics: Anti-HIV Agents; Benzylamines; Cell Line, Tumor; Chemokine CXCL12; Chemotaxis; Colorectal Neoplasms; Cyclams; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Genetic Vectors; Heterocyclic Compounds; Humans; Lentivirus; Neoplasm Invasiveness; Receptor Cross-Talk; Receptors, CXCR4 | 2011 |
OV6⁺ tumor-initiating cells contribute to tumor progression and invasion in human hepatocellular carcinoma.
Topics: AC133 Antigen; Animals; Antigens, CD; Antigens, Differentiation; Antigens, Neoplasm; Benzylamines; Carcinoma, Hepatocellular; Cell Adhesion Molecules; Cell Line, Tumor; Cell Movement; Chemokine CXCL12; Cyclams; Disease Progression; Disease-Free Survival; Epithelial Cell Adhesion Molecule; Female; Gene Knockdown Techniques; Glycoproteins; Heterocyclic Compounds; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Lung Neoplasms; Male; Mice; Mice, Inbred NOD; Mice, SCID; Middle Aged; Multivariate Analysis; Neoplasm Invasiveness; Neoplastic Stem Cells; Peptides; Prognosis; Receptors, CXCR4; RNA, Small Interfering; Spheroids, Cellular | 2012 |
Vinorelbine inhibits angiogenesis and 95D migration via reducing hypoxic fibroblast stromal cell-derived factor 1 secretion.
Topics: Actins; Animals; Antineoplastic Agents, Phytogenic; Aorta, Thoracic; Benzylamines; Capillaries; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chemokine CXCL12; Culture Media, Conditioned; Cyclams; Endothelium, Vascular; Heterocyclic Compounds; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Neoplasm Invasiveness; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Receptors, CXCR4; Stromal Cells; Up-Regulation; Vinblastine; Vinorelbine | 2012 |
Multiple actions of the chemokine CXCL12 on epithelial tumor cells in human ovarian cancer.
Topics: Benzylamines; Cell Division; Chemokine CXCL12; Chemokines, CXC; Cyclams; Enzyme Activation; Female; Heterocyclic Compounds; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Ovarian Neoplasms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, CXCR4; Tumor Necrosis Factor-alpha | 2002 |
The chemokine stromal cell derived factor-1 (CXCL12) promotes glioma invasiveness through MT2-matrix metalloproteinase.
Topics: Animals; Anti-HIV Agents; Benzylamines; Blotting, Western; Cell Proliferation; Chemokine CXCL12; Chemokines, CXC; Collagen; Cyclams; Drug Combinations; Flow Cytometry; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; Heterocyclic Compounds; Humans; Laminin; Matrix Metalloproteinase 15; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Mice; Mice, Nude; Neoplasm Invasiveness; Proteoglycans; Receptors, CXCR4; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Tumor Cells, Cultured | 2005 |
Possible regulation of migration of intrahepatic cholangiocarcinoma cells by interaction of CXCR4 expressed in carcinoma cells with tumor necrosis factor-alpha and stromal-derived factor-1 released in stroma.
Topics: Aged; Aged, 80 and over; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Benzylamines; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chemokine CXCL12; Chemokines, CXC; Cholangiocarcinoma; Cyclams; Female; Fibroblasts; Heterocyclic Compounds; Humans; Liver; Macrophages; Male; Middle Aged; Neoplasm Invasiveness; Receptors, CXCR4; Stromal Cells; Tumor Necrosis Factor-alpha | 2006 |
Roles of the MEK1/2 and AKT pathways in CXCL12/CXCR4 induced cholangiocarcinoma cell invasion.
Topics: Benzylamines; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Butadienes; Cell Line, Tumor; Chemokine CXCL12; Chemokines, CXC; Cholangiocarcinoma; Chromones; Cyclams; Cytoskeleton; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Morpholines; Neoplasm Invasiveness; Nitriles; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Receptors, CXCR4; Signal Transduction | 2007 |
HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion.
Topics: Animals; Antigens, Differentiation; Benzylamines; Bone Marrow Cells; Bone Marrow Transplantation; Brain Neoplasms; Cell Hypoxia; Cell Line; Cell Movement; Chemokine CXCL12; Cyclams; Endothelial Cells; Glioblastoma; Heterocyclic Compounds; Hypoxia-Inducible Factor 1, alpha Subunit; Leukocyte Common Antigens; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Monocytes; Neoplasm Invasiveness; Neovascularization, Pathologic; Pericytes; Receptor, TIE-2; Receptors, CXCR4; Signal Transduction; Transduction, Genetic; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1 | 2008 |
Inhibition of CXCR4 activity with AMD3100 decreases invasion of human colorectal cancer cells in vitro.
Topics: Antineoplastic Agents; Benzylamines; Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Chemokine CXCL12; Colorectal Neoplasms; Cyclams; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Receptors, CXCR4; Reverse Transcriptase Polymerase Chain Reaction; Vascular Endothelial Growth Factor A | 2008 |