Page last updated: 2024-08-24

plerixafor and Cancer of Lung

plerixafor has been researched along with Cancer of Lung in 28 studies

Research

Studies (28)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (7.14)	29.6817
2010's	22 (78.57)	24.3611
2020's	4 (14.29)	2.80

Authors

Authors	Studies
Bai, R; Liang, Z; Shim, H; Wu, R; Xie, Y; Yao, C; Yoon, Y; Yu, W	1
Chen, Y; Ma, J; Qi, Z; Xi, Y	1
Jiang, J; Li, G; Sakurai, K; Shen, N; Song, W; Tang, Z; Yu, H	1
Ge, D; Gu, J; Liu, Z; Lu, C; Mao, W; Shou, H; Xu, F; Zhang, K; Zhang, Z; Zhu, Q	1
Cao, Y; Chen, L; Chen, X; Li, L; Zhou, C	1
Huang, Y; Lu, H; Sheng, X; Xia, R; Xu, G; Xu, X	1
Cui, Y; Lin, J; Pan, H; Peng, Z; Ren, X; Zhang, G	1
Hou, S; Kadoch, O; Li, H; Li, J; Li, S; Li, T; Lin, Q; Xie, L; Xu, Z; Yang, YL	1
Zhao, ZF; Zhou, X; Zhu, WB	1
Cai, Q; Xu, Y; Yan, L	1
Dong, L; Dong, MQ; Fan, QY; Long, H; Ma, BA; Yan, K; Yang, TT; Zhang, P; Zhou, Y	1
Li, J; Oupický, D	1
Archibald, SJ; Bates, J; Hubin, TJ; Jin, J; Lauderdale, J; Panneerselvam, J; Ramesh, R; Shanker, M; Wang, Q; Zhao, YD	1
Bracke, M; De Wagter, C; De Wever, O; Descamps, B; Feys, L; Vanhove, C; Veldeman, L; Vermeulen, S; Vral, A	1
Chen, A; Munshi, A; Muralidharan, R; Panneerselvam, J; Ramesh, R; Zhao, YD	1
An, F; Fang, S; Jin, D; Kong, J; Li, J; Li, X; Lin, B; Liu, L; Liu, T; Luo, Y; Yang, X; Zhang, W	1
Bieche, I; Kieffer, Y; Lefort, S; Marangoni, E; Mechta-Grigoriou, F; Sirven, P; Thuleau, A; Vincent-Salomon, A	1
Braun, F; Burger, M; Catusse, J; Kayser, G; Reichardt, W; Taromi, S; von Elverfeldt, D; Weber, WA; Zeiser, R	1
Bhujwalla, ZM; Green, G; Nimmagadda, S; Pomper, MG; Pullambhatla, M; Stone, K	1
Alitalo, K; Kim, I; Kim, KE; Kim, M; Koh, BI; Koh, GY; Koh, YJ; Nam, DH	1
Burger, JA; Peled, A; Stewart, DJ; Wald, O	1
Jin, YB; Jung, JE; Jung, MJ; Kim, YM; Ko, YG; Lee, JC; Lee, JS; Lee, SJ; Park, MJ; Rho, JK	1
Arra, C; Barbieri, A; Bryce, J; D'Alterio, C; Franco, R; Ieranò, C; Luciano, A; Palma, G; Polimeno, M; Portella, L; Rea, D; Riccio, A; Scala, S; Scognamiglio, G	1
Chen, Y; Feng, GS; Fu, J; He, YQ; Li, YQ; Li, Z; Lin, Y; Liu, Q; Tang, L; Wang, C; Wang, HY; Wu, FQ; Wu, MC; Yan, HX; Yang, W; Yu, LX; Zhang, HL; Zheng, LY; Zou, SS	1
Kinouchi, M; Kuribayashi, N; Miyamoto, Y; Nagai, H; Ohe, G; Tamatani, T; Uchida, D	1
Hwang, ST; Takekoshi, T; Volkman, BF; Ziarek, JJ	1
Garbow, JR; Jackson, E; Luker, GD; Luker, KE; Piwnica-Worms, D; Prior, JL; Smith, MC	1
Begum, NM; Miwa, Y; Onoue, T; Sato, M; Tomizuka, Y; Uchida, D; Yoshida, H	1

Reviews

1 review(s) available for plerixafor and Cancer of Lung

Article	Year
Potential of CXCR4 antagonists for the treatment of metastatic lung cancer. Expert review of anticancer therapy, 2011, Volume: 11, Issue:4 Topics: Animals; Antineoplastic Agents; Benzylamines; Chemokine CXCL12; Cyclams; Heterocyclic Compounds; Humans; Lung Neoplasms; Neoplasm Metastasis; Peptides; Receptors, CXCR4; Tumor Microenvironment	2011

Other Studies

27 other study(ies) available for plerixafor and Cancer of Lung

Article	Year
Amide-sulfamide modulators as effective anti-tumor metastatic agents targeting CXCR4/CXCL12 axis. European journal of medicinal chemistry, 2020, Jan-01, Volume: 185 Topics: Amides; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Adhesion; Cell Proliferation; Chemokine CXCL12; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Injections, Intravenous; Lung Neoplasms; Mice; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Receptors, CXCR4; Structure-Activity Relationship; Tumor Cells, Cultured; Wound Healing	2020
PTEN loss activates a functional AKT/CXCR4 signaling axis to potentiate tumor growth and lung metastasis in human osteosarcoma cells. Clinical & experimental metastasis, 2020, Volume: 37, Issue:1 Topics: Animals; Benzylamines; Bone and Bones; Bone Neoplasms; Cell Line, Tumor; Cyclams; Down-Regulation; Gene Knockdown Techniques; Heterocyclic Compounds; Humans; Lung; Lung Neoplasms; Male; Mice; Osteosarcoma; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Receptors, CXCR4; RNA, Small Interfering; Signal Transduction; Xenograft Model Antitumor Assays	2020
Combretastatin A4 nanodrug combined plerixafor for inhibiting tumor growth and metastasis simultaneously. Biomaterials science, 2019, Dec-01, Volume: 7, Issue:12 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzylamines; Breast Neoplasms; Cell Proliferation; Cell Survival; Cyclams; Female; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds; Humans; Lung Neoplasms; Mice; Receptors, CXCR4; Stilbenes; Theranostic Nanomedicine; Up-Regulation; Xenograft Model Antitumor Assays	2019
Gefitinib promotes CXCR4-dependent epithelial to mesenchymal transition via TGF-β1 signaling pathway in lung cancer cells harboring EGFR mutation. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2020, Volume: 22, Issue:8 Topics: Adenocarcinoma of Lung; Antineoplastic Agents; Benzylamines; Cell Line, Tumor; Cell Movement; Chemokine CXCL12; Cyclams; Epithelial-Mesenchymal Transition; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Mutation; Neoplasm Proteins; Receptors, CXCR4; RNA, Small Interfering; Smad2 Protein; Transforming Growth Factor beta1; Up-Regulation	2020
Adenosine A2A receptor activation reduces brain metastasis via SDF-1/CXCR4 axis and protecting blood-brain barrier. Molecular carcinogenesis, 2020, Volume: 59, Issue:4 Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Benzylamines; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Chemokine CXCL12; Cyclams; Heterocyclic Compounds; Humans; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Phenethylamines; Receptor, Adenosine A2A; Receptors, CXCR4; Xenograft Model Antitumor Assays	2020
Hesperidin suppresses the migration and invasion of non-small cell lung cancer cells by inhibiting the SDF-1/CXCR-4 pathway. Life sciences, 2018, May-15, Volume: 201 Topics: A549 Cells; Antineoplastic Agents, Phytogenic; Benzylamines; Carcinoma, Non-Small-Cell Lung; Cell Movement; Chemokine CXCL12; Chemotaxis; Cyclams; Dose-Response Relationship, Drug; Hesperidin; Heterocyclic Compounds; Humans; Lung Neoplasms; Neoplasm Invasiveness; Neoplasm Proteins; Receptors, CXCR4; Signal Transduction; Wound Healing	2018
Forkhead box C1 boosts triple-negative breast cancer metastasis through activating the transcription of chemokine receptor-4. Cancer science, 2018, Volume: 109, Issue:12 Topics: Animals; Benzylamines; Cell Line, Tumor; Cell Movement; Cyclams; Female; Forkhead Transcription Factors; Heterocyclic Compounds; Humans; Lung Neoplasms; Mice; Neoplasm Transplantation; Receptors, CXCR4; Transcriptional Activation; Triple Negative Breast Neoplasms; Zebrafish	2018
Experimental study of the inhibition effect of CXCL12/CXCR4 in malignant pleural mesothelioma. Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2019, Volume: 67, Issue:2 Topics: Animals; Benzylamines; Cell Line, Tumor; Chemokine CXCL12; Cyclams; Female; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds; Luminescent Measurements; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Mice, Inbred BALB C; Mice, Nude; Pemetrexed; Pleural Neoplasms; Protein Isoforms; Receptors, CXCR4; Signal Transduction	2019
AMD3100 inhibits epithelial-mesenchymal transition, cell invasion, and metastasis in the liver and the lung through blocking the SDF-1α/CXCR4 signaling pathway in prostate cancer. Journal of cellular physiology, 2019, Volume: 234, Issue:7 Topics: Animals; Benzylamines; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Shape; Cell Survival; Chemokine CXCL12; Cyclams; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds; Liver Neoplasms; Lung Neoplasms; Male; Mice, Nude; Neoplasm Invasiveness; Neoplasm Proteins; Phosphorylation; Prostatic Neoplasms; Receptors, CXCR4; RNA, Messenger; Signal Transduction	2019
The ubiquitin-CXCR4 axis plays an important role in acute lung infection-enhanced lung tumor metastasis. Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Sep-01, Volume: 19, Issue:17 Topics: Acute Lung Injury; Animals; Benzylamines; Bronchoalveolar Lavage Fluid; Cell Line, Tumor; Cell Movement; Cyclams; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds; Humans; Lipopolysaccharides; Lung Neoplasms; Mice; Receptors, CXCR4; Ubiquitin; Xenograft Model Antitumor Assays	2013
CXCR4-mediated osteosarcoma growth and pulmonary metastasis is promoted by mesenchymal stem cells through VEGF. Oncology reports, 2013, Volume: 30, Issue:4 Topics: Animals; Benzylamines; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Coculture Techniques; Culture Media, Conditioned; Cyclams; Heterocyclic Compounds; Heterografts; Humans; Lung Neoplasms; Male; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Osteosarcoma; Receptors, CXCR4; Vascular Endothelial Growth Factor A	2013
Effect of biodegradability on CXCR4 antagonism, transfection efficacy and antimetastatic activity of polymeric Plerixafor. Biomaterials, 2014, Volume: 35, Issue:21 Topics: Animals; Anticarcinogenic Agents; Benzylamines; Chemical Phenomena; Chemokine CXCL12; Cyclams; Disease Models, Animal; Drug Delivery Systems; Female; Hep G2 Cells; Heterocyclic Compounds; Humans; Lung Neoplasms; Mice; Mice, Inbred C57BL; Plasmids; Protein Binding; Receptors, CXCR4; Transfection	2014
IL-24 inhibits lung cancer cell migration and invasion by disrupting the SDF-1/CXCR4 signaling axis. PloS one, 2015, Volume: 10, Issue:3 Topics: Benzylamines; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Chemokine CXCL12; Cyclams; Drug Synergism; Gene Expression; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds; Humans; Interleukins; Lung Neoplasms; Proto-Oncogene Proteins c-akt; Receptors, CXCR4; RNA, Small Interfering; Signal Transduction; TOR Serine-Threonine Kinases	2015
Radiation-induced lung damage promotes breast cancer lung-metastasis through CXCR4 signaling. Oncotarget, 2015, Sep-29, Volume: 6, Issue:29 Topics: Animals; Benzylamines; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Survival; Cellular Senescence; Chemokine CXCL12; Culture Media, Conditioned; Cyclams; DNA Breaks, Double-Stranded; Extracellular Signal-Regulated MAP Kinases; Female; Heterocyclic Compounds; Humans; Intramolecular Oxidoreductases; Lung; Lung Diseases; Lung Neoplasms; Macrophage Migration-Inhibitory Factors; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Proto-Oncogene Proteins c-akt; Radiotherapy; Receptors, CXCR4; Recombinant Proteins; Signal Transduction; STAT3 Transcription Factor	2015
HuR-targeted nanotherapy in combination with AMD3100 suppresses CXCR4 expression, cell growth, migration and invasion in lung cancer. Cancer gene therapy, 2015, Volume: 22, Issue:12 Topics: Antineoplastic Agents; Benzylamines; Cell Movement; Cell Proliferation; Combined Modality Therapy; Cyclams; Down-Regulation; ELAV-Like Protein 1; Heterocyclic Compounds; Humans; Lung Neoplasms; Nanoparticles; Neoplasm Invasiveness; Receptors, CXCR4; RNA, Small Interfering	2015
A novel microfluidic model can mimic organ-specific metastasis of circulating tumor cells. Oncotarget, 2016, Nov-29, Volume: 7, Issue:48 Topics: Animals; Antineoplastic Agents; Benzylamines; Breast Neoplasms; Cell Adhesion; Cell Movement; Chemokines; Coculture Techniques; Cyclams; Female; Heterocyclic Compounds; Human Umbilical Vein Endothelial Cells; Humans; Lab-On-A-Chip Devices; Lung Neoplasms; MCF-7 Cells; Mice, Inbred BALB C; Mice, Nude; Microfluidic Analytical Techniques; Neoplasm Invasiveness; Neoplastic Cells, Circulating; Organ Specificity; Primary Cell Culture; Rats, Sprague-Dawley; Salivary Gland Neoplasms; Time Factors	2016
CXCR4 inhibitors could benefit to HER2 but not to triple-negative breast cancer patients. Oncogene, 2017, 03-02, Volume: 36, Issue:9 Topics: Animals; Anti-HIV Agents; Apoptosis; Benzylamines; Biomarkers, Tumor; Breast Neoplasms; Cell Proliferation; Cyclams; Female; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds; Humans; Lung Neoplasms; Mice; Neoplasm Invasiveness; Neovascularization, Pathologic; Peptides; Receptor, ErbB-2; Receptors, CXCR4; Signal Transduction; Triple Negative Breast Neoplasms; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2017
CXCR4 antagonists suppress small cell lung cancer progression. Oncotarget, 2016, Dec-20, Volume: 7, Issue:51 Topics: Animals; Benzylamines; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cisplatin; Cyclams; DNA-Binding Proteins; Drug Resistance, Neoplasm; Etoposide; Heterocyclic Compounds; Humans; Lung Neoplasms; Mice; Mice, Knockout; Neoplasm Metastasis; Nuclear Proteins; Peptides; Receptors, CXCR4; Small Cell Lung Carcinoma; Xenograft Model Antitumor Assays	2016
Molecular imaging of CXCR4 receptor expression in human cancer xenografts with [64Cu]AMD3100 positron emission tomography. Cancer research, 2010, May-15, Volume: 70, Issue:10 Topics: Animals; Benzylamines; Blotting, Western; Copper Radioisotopes; Cyclams; Female; Flow Cytometry; Heterocyclic Compounds; Humans; Immunoenzyme Techniques; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred NOD; Mice, SCID; Positron-Emission Tomography; Receptors, CXCR4; Tissue Distribution; Tomography, X-Ray Computed	2010
CXCR4 signaling regulates metastasis of chemoresistant melanoma cells by a lymphatic metastatic niche. Cancer research, 2010, Dec-15, Volume: 70, Issue:24 Topics: AC133 Antigen; Animals; Antigens, CD; Benzylamines; Cell Movement; Chemokine CXCL12; Cyclams; Dacarbazine; Drug Resistance, Neoplasm; Endothelial Cells; Glycoproteins; Heterocyclic Compounds; Lung Neoplasms; Lymphatic Metastasis; Lymphatic Vessels; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Transgenic; Peptides; Receptors, CXCR4; Signal Transduction	2010
Upregulation of CXCR4 is functionally crucial for maintenance of stemness in drug-resistant non-small cell lung cancer cells. Oncogene, 2013, Jan-10, Volume: 32, Issue:2 Topics: Animals; Benzylamines; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chemokine CXCL12; Cyclams; Drug Resistance, Neoplasm; Female; Heterocyclic Compounds; Humans; Lung Neoplasms; Mice; Mice, Nude; Mice, SCID; Neoplastic Stem Cells; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pyridines; Receptors, CXCR4; RNA Interference; RNA, Small Interfering; Signal Transduction; STAT3 Transcription Factor; TOR Serine-Threonine Kinases; Tyrphostins; Up-Regulation	2013
Inhibition of stromal CXCR4 impairs development of lung metastases. Cancer immunology, immunotherapy : CII, 2012, Volume: 61, Issue:10 Topics: Animals; Antigens, Ly; Antineoplastic Agents; Benzylamines; Cyclams; Female; Granulocytes; Heterocyclic Compounds; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Receptors, CXCR4; Stromal Cells	2012
OV6⁺ tumor-initiating cells contribute to tumor progression and invasion in human hepatocellular carcinoma. Journal of hepatology, 2012, Volume: 57, Issue:3 Topics: AC133 Antigen; Animals; Antigens, CD; Antigens, Differentiation; Antigens, Neoplasm; Benzylamines; Carcinoma, Hepatocellular; Cell Adhesion Molecules; Cell Line, Tumor; Cell Movement; Chemokine CXCL12; Cyclams; Disease Progression; Disease-Free Survival; Epithelial Cell Adhesion Molecule; Female; Gene Knockdown Techniques; Glycoproteins; Heterocyclic Compounds; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Lung Neoplasms; Male; Mice; Mice, Inbred NOD; Mice, SCID; Middle Aged; Multivariate Analysis; Neoplasm Invasiveness; Neoplastic Stem Cells; Peptides; Prognosis; Receptors, CXCR4; RNA, Small Interfering; Spheroids, Cellular	2012
Expression and function of CXCR4 in human salivary gland cancers. Clinical & experimental metastasis, 2013, Volume: 30, Issue:2 Topics: Animals; Benzylamines; Blotting, Western; Carcinoma, Squamous Cell; Cell Adhesion; Cell Movement; Chemokine CXCL12; Cyclams; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Heterocyclic Compounds; Humans; Immunoenzyme Techniques; Lung Neoplasms; Lymphatic Metastasis; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinase 3; Real-Time Polymerase Chain Reaction; Receptors, CXCR4; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Salivary Gland Neoplasms; Tumor Cells, Cultured	2013
A locked, dimeric CXCL12 variant effectively inhibits pulmonary metastasis of CXCR4-expressing melanoma cells due to enhanced serum stability. Molecular cancer therapeutics, 2012, Volume: 11, Issue:11 Topics: Animals; Benzylamines; Calcium; Cell Proliferation; Chemokine CXCL12; Cyclams; Dipeptidyl Peptidase 4; Heterocyclic Compounds; Humans; Lung Neoplasms; Matrix Metalloproteinase 2; Melanoma; Mice; Mice, Inbred C57BL; Protein Multimerization; Protein Stability; Receptors, CXCR4; Serum	2012
CXCR4 regulates growth of both primary and metastatic breast cancer. Cancer research, 2004, Dec-01, Volume: 64, Issue:23 Topics: Animals; Benzylamines; Cell Growth Processes; Cell Line, Tumor; Cyclams; Disease Models, Animal; Female; Heterocyclic Compounds; Lung Neoplasms; Magnetic Resonance Imaging; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Knockout; Neoplasm Metastasis; Neoplasm Transplantation; Receptors, CXCR4; RNA Interference; Transfection	2004
Involvement of an autocrine stromal cell derived factor-1/CXCR4 system on the distant metastasis of human oral squamous cell carcinoma. Molecular cancer research : MCR, 2007, Volume: 5, Issue:7 Topics: Aged; Aged, 80 and over; Animals; Autocrine Communication; Benzylamines; Carcinoma, Squamous Cell; Chemokine CXCL12; Chemokines, CXC; Cyclams; Female; Heterocyclic Compounds; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Mice; Mice, Nude; Middle Aged; Mouth Neoplasms; Phenotype; Receptors, CXCR4; Survival Analysis	2007