plerixafor has been researched along with Benign Neoplasms in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (13.79) | 29.6817 |
| 2010's | 19 (65.52) | 24.3611 |
| 2020's | 6 (20.69) | 2.80 |
| Authors | Studies |
|---|---|
| Garofalo, A; Giancotti, G; Grande, F; Ioele, G; Occhiuzzi, MA | 1 |
| Chen, CW; Chihade, DB; Coopersmith, CM; Ford, ML; Liang, Z; Ramonell, KM; Xie, J; Zhang, W | 1 |
| Bader, P; Bernard, J; Bisogno, G; Dallorso, S; Doyle, E; Kepak, T; Kriván, G; Lang, P; Liu, Q; Locatelli, F; Luksch, R; Maecker-Kolhoff, B; Morland, B; Murphy, D; Rößler, J; Sevilla, J; Sumerauer, D; Yaniv, I; Zwaan, CM | 1 |
| Brown, JM | 1 |
| Chen, H; Poznansky, MC; Tannous, BA; Wang, J | 1 |
| Abu-Arja, R; Bhunia, N; Dalal, JD; Goyal, RK; Kang, HJ; Lee, AC; Loeb, DM; Mehyar, LS; O'Brien, TA; Ozkaynak, MF; Rangarajan, HG; Roberts, CH; Shaw, PJ; Shenoy, SS; Stanek, JR; Stein, J; Strahlendorf, C | 1 |
| Lai, WY; Mueller, A | 1 |
| Douglas, KW; Gilleece, M; Hayden, P; Hunter, H; Johnson, PRE; Kallmeyer, C; Malladi, RK; Paneesha, S; Pawson, R; Quinn, M; Raj, K; Richardson, D; Robinson, S; Russell, N; Snowden, J; Sureda, A; Tholouli, E; Thomson, K; Watts, M; Wilson, KM | 1 |
| Bonecchi, R; Capucetti, A; Massara, M; Mollica Poeta, V | 1 |
| Guest, J | 1 |
| Ando, Y; Guo, J; Hayashi, M; Hiraki, A; Jono, H; Nakamura, T; Nakayama, H; Shinohara, M; Shinriki, S; Ueda, M; Yamashita, S; Zijlstra, A | 1 |
| Patel, B; Pearson, H; Zacharoulis, S | 1 |
| Balashov, DN; Boyakova, EV; Kurnikova, EE; Maschan, AA; Maschan, MA; Novichkova, GA; Skorobogatova, EV; Trakhtman, PE | 1 |
| Abdul Razak, AR; Bartha-Vári, JH; Boros, Z; Cai, S; Carlson, R; Chong, YS; Chua, SY; Dagis, A; Feng, X; Foo, VH; Gabrail, NY; Gerecitano, JF; Gluckman, P; Huber, S; Ikram, MK; Irimie, FD; Kauffman, M; Kim, R; Kwek, K; Landesman, Y; Lassen, U; Li, D; Li, Q; Liu, C; Ma, J; Mahipal, A; Mau-Soerensen, M; McCauley, D; Mirza, MR; Nademanee, A; Ngo, C; Paizs, C; Palmer, JM; Pizzari, T; Poppe, L; Rashal, T; Saint-Martin, JR; Saw, SM; Shacham, S; Shields, AF; Stayner, LA; Tan, CS; Thorborg, K; Toşa, MI; Tsai, NC; Unger, TJ; Verkicharla, PK; Vértessy, BG; Wang, S; Wang, Y; Weiser, D; Wollin, M; Wong, TY; Xu, L; Yuan, L; Yuan, S; Zhang, Y; Zheng, R | 1 |
| Baracos, VE; Bathe, OF; Cervo, L; Giavazzi, R; Lecker, SH; Martinelli, GB; Olivari, D; Ottoboni, L; Piccirillo, R; Re Cecconi, AD; Resovi, A; Stretch, C; Talamini, L | 1 |
| Ataca Atilla, P; Bakanay Ozturk, SM; Demirer, T | 1 |
| Lazennec, G; Richmond, A | 1 |
| Li, G; Song, C | 1 |
| Duda, DG; Fukumura, D; Jain, RK; Kirkpatrick, ND; Kozin, SV; Xu, L | 1 |
| Avramova, BE; Bobev, DG; Konstantinov, DN; Yordanova, MN | 1 |
| Apperley, JF; Basak, GW; Douglas, KW; Duarte, RF; Gabriel, IH; Geraldes, C; Hübel, K; Jaksic, O; Koristek, Z; Lanza, F; Lemoli, R; Mikala, G; Mohty, M; Selleslag, D; Worel, N | 1 |
| Andreola, G; Babic, A; Laszlo, D; Martinelli, G; Negri, M; Rabascio, C; Radice, D; Vanazzi, A | 1 |
| Cushing, M; Shore, T; Van Besien, K; Villa, CH | 1 |
| McAlpine, SR; Ramsey, DM | 1 |
| Jacobson, O; Weiss, ID | 1 |
| De Clercq, E | 2 |
| Archibald, SJ; Greenman, J; Khan, A | 1 |
13 review(s) available for plerixafor and Benign Neoplasms
| Article | Year |
|---|---|
An update on small molecules targeting CXCR4 as starting points for the development of anti-cancer therapeutics.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Humans; Molecular Structure; Neoplasms; Receptors, CXCR4; Small Molecule Libraries; Structure-Activity Relationship | 2017 |
Radiation Damage to Tumor Vasculature Initiates a Program That Promotes Tumor Recurrences.
Topics: Benzylamines; Blood Vessels; Bone Marrow Cells; Cell Polarity; Chemokine CXCL12; Cyclams; Endothelial Cells; Humans; Hypoxia-Inducible Factor 1; Neoplasm Recurrence, Local; Neoplasms; Radiotherapy Dosage; Reactive Oxygen Species; Receptors, CXCR4; Tumor Hypoxia; Tumor-Associated Macrophages | 2020 |
CXCR4 antagonist AMD3100 (plerixafor): From an impurity to a therapeutic agent.
Topics: Animals; Anti-HIV Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Autoimmune Diseases; Benzylamines; Cyclams; Drug Contamination; HIV Infections; Humans; Neoplasms; Primary Immunodeficiency Diseases; Receptors, CXCR4; Signal Transduction; Tumor Microenvironment; Warts | 2020 |
Latest update on chemokine receptors as therapeutic targets.
Topics: Animals; Antibodies, Monoclonal, Humanized; Benzylamines; Chemokines; Cyclams; Humans; Inflammation; Maraviroc; Molecular Targeted Therapy; Neoplasms; Protein Binding; Receptors, Chemokine; Signal Transduction | 2021 |
UK consensus statement on the use of plerixafor to facilitate autologous peripheral blood stem cell collection to support high-dose chemoradiotherapy for patients with malignancy.
Topics: Benzylamines; Chemoradiotherapy; Consensus; Cyclams; Hematopoietic Stem Cell Mobilization; Heterocyclic Compounds; Humans; Neoplasms; Peripheral Blood Stem Cell Transplantation; Peripheral Blood Stem Cells; Premedication; Transplantation, Autologous; United Kingdom | 2018 |
Chemokines and Chemokine Receptors: New Targets for Cancer Immunotherapy.
Topics: Antibodies, Monoclonal, Humanized; Benzylamines; Chemokines, CC; Chemokines, CXC; Cyclams; Heterocyclic Compounds; Humans; Immunotherapy; Molecular Targeted Therapy; Neoplasms; Receptors, CCR; Receptors, CXCR | 2019 |
How to manage poor mobilizers for high dose chemotherapy and autologous stem cell transplantation?
Topics: Antineoplastic Agents; Autografts; Benzylamines; Cyclams; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells; Heterocyclic Compounds; Humans; Leukapheresis; Neoplasms; Stem Cell Transplantation | 2017 |
Chemokines and chemokine receptors: new insights into cancer-related inflammation.
Topics: Benzylamines; Chemokines; Clinical Trials as Topic; Cyclams; Heterocyclic Compounds; Humans; Inflammation; Models, Biological; Neoplasms; Receptors, Chemokine; Receptors, CXCR4 | 2010 |
CXCL12 (SDF1alpha)-CXCR4/CXCR7 pathway inhibition: an emerging sensitizer for anticancer therapies?
Topics: Animals; Benzylamines; Chemokine CXCL12; Cyclams; Heterocyclic Compounds; Humans; Models, Biological; Neoplasms; Peptides; Receptors, CXCR; Receptors, CXCR4; Signal Transduction | 2011 |
Halting metastasis through CXCR4 inhibition.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Benzylamines; Binding Sites; Chemokine CXCL12; Clinical Trials as Topic; Cyclams; Heterocyclic Compounds; Humans; Neoplasm Metastasis; Neoplasms; Peptides; Receptors, CXCR4; Single-Domain Antibodies | 2013 |
The bicyclam AMD3100 story.
Topics: Amino Acid Sequence; Animals; Anti-HIV Agents; Benzylamines; Cyclams; Heart; Heterocyclic Compounds; HIV Envelope Protein gp120; Humans; Molecular Sequence Data; Neoplasms; Receptors, CXCR4 | 2003 |
Potential clinical applications of the CXCR4 antagonist bicyclam AMD3100.
Topics: Animals; Anti-HIV Agents; Benzylamines; Cyclams; Heterocyclic Compounds; HIV-1; Humans; Neoplasms; Receptors, CXCR4 | 2005 |
Small molecule CXCR4 chemokine receptor antagonists: developing drug candidates.
Topics: Animals; Anti-HIV Agents; Antineoplastic Agents; Benzylamines; Chemokine CXCL12; Chemokines; Cyclams; Heterocyclic Compounds; HIV Infections; Humans; Neoplasms; Receptors, CXCR4; Structure-Activity Relationship | 2007 |
2 trial(s) available for plerixafor and Benign Neoplasms
| Article | Year |
|---|---|
Plerixafor combined with standard regimens for hematopoietic stem cell mobilization in pediatric patients with solid tumors eligible for autologous transplants: two-arm phase I/II study (MOZAIC).
Topics: Adolescent; Autografts; Benzylamines; Child; Cyclams; Hematopoietic Stem Cell Mobilization; Heterocyclic Compounds; Humans; Neoplasms | 2020 |
Topics: Active Transport, Cell Nucleus; Adolescent; Adult; Aged; Aged, 80 and over; Atrial Natriuretic Factor; Benzhydryl Compounds; Benzylamines; Biopsy; Blood Glucose; Blood Transfusion; Cholesterol, LDL; Combined Modality Therapy; Cyclams; Diabetes Mellitus, Type 2; Disease Progression; Drug Administration Schedule; Enzyme-Linked Immunosorbent Assay; Female; Glucosides; Glycated Hemoglobin; Granulocyte Colony-Stimulating Factor; Hamstring Muscles; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Heterocyclic Compounds; Hodgkin Disease; Humans; Hydrazines; Immunohistochemistry; Insulin-Secreting Cells; Leg; Male; Middle Aged; Muscle Strength; Neoplasms; Peripheral Blood Stem Cell Transplantation; Range of Motion, Articular; Recurrence; Remission Induction; Research Design; Reverse Transcriptase Polymerase Chain Reaction; Soccer; Sodium-Glucose Transport Proteins; Sodium-Glucose Transporter 2 Inhibitors; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome; Triazoles; Young Adult | 2015 |
14 other study(ies) available for plerixafor and Benign Neoplasms
| Article | Year |
|---|---|
Preexisting malignancy abrogates the beneficial effects of CXCR4 blockade during sepsis.
Topics: Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Benzylamines; Biomarkers; Bone Marrow; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cecum; Cyclams; Female; Heterocyclic Compounds; Lectins, C-Type; Ligation; Male; Mice, Inbred C57BL; Neoplasms; Punctures; Receptors, CXCR4; Sepsis; Spleen; Up-Regulation | 2020 |
A multicenter report on the safety and efficacy of plerixafor based stem cell mobilization in children with malignant disorders.
Topics: Adolescent; Antigens, CD34; Benzylamines; Blood Component Removal; Child; Child, Preschool; Cohort Studies; Cyclams; Female; Hematopoietic Stem Cell Mobilization; Humans; Infant; Lymphoma; Male; Medulloblastoma; Neoplasms; Neuroblastoma; Peripheral Blood Stem Cells; Retrospective Studies; Sarcoma; Young Adult | 2021 |
High efficiency stem cell collection collecting from children and adolescents.
Topics: Adolescent; Adult; Anti-HIV Agents; Benzylamines; Child; Child, Preschool; Cyclams; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells; Heterocyclic Compounds; Humans; Infant; Leukapheresis; Male; Neoplasms; Peripheral Blood Stem Cell Transplantation; Transplantation, Autologous | 2013 |
Intrinsic TGF-β2-triggered SDF-1-CXCR4 signaling axis is crucial for drug resistance and a slow-cycling state in bone marrow-disseminated tumor cells.
Topics: Animals; Antineoplastic Agents; Benzylamines; Bone Marrow; Cell Line, Tumor; Chemokine CXCL12; Cisplatin; Cyclams; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds; Humans; Immunoblotting; Mice; Neoplasms; Receptors, CXCR4; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Transforming Growth Factor beta2; Transplantation, Heterologous | 2015 |
Mobilisation of haematopoietic stem cells in paediatric patients, prior to autologous transplantation following administration of plerixafor and G-CSF.
Topics: Anti-HIV Agents; Antigens, CD34; Benzylamines; Chemokine CXCL12; Child; Child, Preschool; Cyclams; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Heterocyclic Compounds; Humans; Infant; Male; Neoplasms; Receptors, CXCR4; Retrospective Studies; Transplantation, Autologous; Treatment Outcome | 2015 |
Efficacy of plerixafor in children with malignant tumors failing to mobilize a sufficient number of hematopoietic progenitors with G-CSF.
Topics: Adolescent; Autografts; Benzylamines; Child; Child, Preschool; Cyclams; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Heterocyclic Compounds; Humans; Infant; Male; Neoplasms | 2015 |
Activation of the SDF1/CXCR4 pathway retards muscle atrophy during cancer cachexia.
Topics: Animals; Benzylamines; Biomarkers; Cachexia; Chemokine CXCL12; Cyclams; Cytokines; Disease Models, Animal; Female; Gene Expression; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds; Humans; Indoles; Male; Mice; Muscle Fibers, Skeletal; Muscle, Skeletal; Muscular Atrophy; Neoplasms; Pyrroles; Rats; Receptors, CXCR4; Signal Transduction; Sunitinib | 2016 |
CXCR4 and matrix metalloproteinase-2 are involved in mesenchymal stromal cell homing and engraftment to tumors.
Topics: Animals; Benzylamines; Cell Line, Tumor; Cell Movement; Culture Media, Conditioned; Cyclams; Gene Expression Profiling; Heterocyclic Compounds; Humans; Matrix Metalloproteinase 2; Mesenchymal Stem Cells; Mice; Neoplasms; Rats; Rats, Sprague-Dawley; Receptors, CXCR4; Stromal Cells; Xenograft Model Antitumor Assays | 2011 |
Successful mobilization of peripheral blood stem cells in children with cancer using plerixafor (Mozobil) and granulocyte-colony stimulating factor.
Topics: Adolescent; Antigens, CD34; Benzylamines; Blood Cell Count; Child; Cyclams; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Heterocyclic Compounds; Humans; Leukapheresis; Male; Neoplasms; Peripheral Blood Stem Cell Transplantation; Transplantation, Autologous; Treatment Outcome | 2011 |
European data on stem cell mobilization with plerixafor in patients with nonhematologic diseases: an analysis of the European consortium of stem cell mobilization.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Antineoplastic Agents; Benzylamines; Blood Component Removal; Bone Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Cyclams; Europe; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Heterocyclic Compounds; Humans; Male; Middle Aged; Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuroblastoma; Sarcoma, Ewing; Stem Cell Transplantation; Wiskott-Aldrich Syndrome; Young Adult | 2012 |
Who should be really considered as a poor mobilizer in the plerixafor era?
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Benzylamines; Cyclams; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Heterocyclic Compounds; Humans; Male; Middle Aged; Neoplasms; Peripheral Blood Stem Cell Transplantation; Receptors, CXCR4; Retrospective Studies; Risk Factors; Transplantation, Autologous | 2012 |
Addition of plerixafor to mobilization regimens in autologous peripheral blood stem cell transplants does not affect the correlation of preharvest hematopoietic precursor cell enumeration with first-harvest CD34+ stem cell yield.
Topics: Adult; Aged; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Benzylamines; Combined Modality Therapy; Cyclams; Female; Hematopoietic Stem Cell Mobilization; Heterocyclic Compounds; Humans; Male; Middle Aged; Neoplasms; Peripheral Blood Stem Cell Transplantation; Receptors, CXCR4; Retrospective Studies; Young Adult | 2012 |
CXCR4 chemokine receptor overview: biology, pathology and applications in imaging and therapy.
Topics: Animals; Benzylamines; Cyclams; Diagnostic Imaging; Heterocyclic Compounds; HIV Infections; Humans; Mice; Neoplasms; Receptors, CXCR4 | 2013 |
Plerixafor: AMD 3100, AMD3100, JM 3100, SDZ SID 791.
Topics: Animals; Benzylamines; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclams; Hematologic Diseases; Heterocyclic Compounds; Mice; Neoplasms; Rats; Receptors, CXCR4; Stem Cells; Virus Diseases | 2007 |