Page last updated: 2024-08-24

plerixafor and Antibody Deficiency Syndrome

plerixafor has been researched along with Antibody Deficiency Syndrome in 10 studies

Research

Authors	Studies
De Filippo, K; Rankin, SM	1
Bianchi, DA; Blair, EA; Buck, CB; Calvo, KR; Cho, E; Gardner, PJ; Landon, EM; Liu, Q; McDermott, DH; Murphy, PM; Neves, JF; Pastrana, DV; Pittaluga, S; Silva, SL; Trout, HH; Velez, D	1
Al Ustwani, O; Kurzrock, R; Wetzler, M	1
Anaya-O'Brien, S; Calvo, KR; Cowen, EW; DeCastro, R; Evbuomwan, MO; Fleisher, TA; Giuntoli, RL; Grimes, GJ; Hilligoss, D; Hwang, ST; Kuhns, DB; Kwatemaa, N; Littel, P; Liu, Q; Lopez, L; Malech, HL; Marquesen, MM; McDermott, DH; Merideth, MA; Murphy, PM; Pittaluga, S; Priel, DA; Starling, J; Stratton, P; Ulrick, J; Velez, D	1
Broxmeyer, HE	1
Anaya-O'Brien, S; Chen, H; DeCastro, R; Deng, F; Garofalo, M; Hilligoss, D; Kelly, C; Kwatemaa, N; Liu, Q; Lopez, J; Malech, HL; Marquesen, M; McDermott, DH; Murphy, PM; Ojode, T; Ulrick, J	1
Badolato, R; Dotta, L; Tassone, L	1
Aprikyan, A; Bolyard, AA; Dale, DC; Hsu, FJ; Kelley, ML; Makaryan, V; Westrup, EC; Wood, B	1
Anaya-O'Brien, S; Decastro, R; Filho, JO; Fleisher, TA; Garofalo, M; Hilligoss, D; Kelly, C; Kuhns, DB; Kwatemaa, N; Littel, P; Liu, Q; Malech, HL; Marquesen, MM; McDermott, DH; Murphy, PM; Penzak, SR; Priel, DA; Ulrick, J	1
Diaz, GA	1

3 review(s) available for plerixafor and Antibody Deficiency Syndrome

Article	Year
CXCR4, the master regulator of neutrophil trafficking in homeostasis and disease. European journal of clinical investigation, 2018, Volume: 48 Suppl 2 Topics: Animals; Benzylamines; Bone Marrow; Cell Survival; Chemokine CXCL12; Cyclams; Hematologic Agents; Heterocyclic Compounds; HMGB1 Protein; Homeostasis; Humans; Imidazoles; Immunologic Deficiency Syndromes; Inflammation; Mice; Mutation; Neutrophils; Peptide Fragments; Primary Immunodeficiency Diseases; Receptors, CXCR4; Serum Albumin; Spleen; Warts	2018
Genetics on a WHIM. British journal of haematology, 2014, Volume: 164, Issue:1 Topics: Animals; Benzylamines; Cyclams; Heterocyclic Compounds; Humans; Immunologic Deficiency Syndromes; Primary Immunodeficiency Diseases; Receptors, CXCR4; Warts	2014
Clinical and genetic features of Warts, Hypogammaglobulinemia, Infections and Myelokathexis (WHIM) syndrome. Current molecular medicine, 2011, Volume: 11, Issue:4 Topics: Agammaglobulinemia; Anti-Bacterial Agents; Bacterial Infections; Benzylamines; Bone Marrow; Chemokine CXCL12; Cyclams; Female; Granulocyte Colony-Stimulating Factor; Heterocyclic Compounds; Humans; Immunologic Deficiency Syndromes; Lymphopenia; Male; Mutation; Neutropenia; Neutrophils; Primary Immunodeficiency Diseases; Receptors, CXCR4; Signal Transduction; Warts	2011

3 trial(s) available for plerixafor and Antibody Deficiency Syndrome

Article	Year
A phase 1 clinical trial of long-term, low-dose treatment of WHIM syndrome with the CXCR4 antagonist plerixafor. Blood, 2014, Apr-10, Volume: 123, Issue:15 Topics: Adult; Benzylamines; Cyclams; Female; Flow Cytometry; Heterocyclic Compounds; Humans; Immunologic Deficiency Syndromes; Male; Middle Aged; Primary Immunodeficiency Diseases; Receptors, CXCR4; Time Factors; Warts	2014
The CXCR4 antagonist plerixafor is a potential therapy for myelokathexis, WHIM syndrome. Blood, 2011, Nov-03, Volume: 118, Issue:18 Topics: Adult; Aged; Anti-HIV Agents; Benzylamines; Bone Marrow Diseases; Cyclams; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Granulocyte Precursor Cells; Heterocyclic Compounds; Humans; Immunologic Deficiency Syndromes; Leukopenia; Male; Middle Aged; Primary Immunodeficiency Diseases; Receptors, CXCR4; Warts	2011
The CXCR4 antagonist plerixafor corrects panleukopenia in patients with WHIM syndrome. Blood, 2011, Nov-03, Volume: 118, Issue:18 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Benzylamines; Blood Cell Count; Cyclams; Dose-Response Relationship, Drug; Female; Heterocyclic Compounds; Humans; Immunologic Deficiency Syndromes; Leukocytes; Lymphopenia; Male; Middle Aged; Primary Immunodeficiency Diseases; Receptors, CXCR4; Treatment Outcome; Warts; Young Adult	2011

4 other study(ies) available for plerixafor and Antibody Deficiency Syndrome

Article	Year
Plerixafor for the Treatment of WHIM Syndrome. The New England journal of medicine, 2019, 01-10, Volume: 380, Issue:2 Topics: Benzylamines; Bone Marrow; Bone Marrow Examination; Cyclams; Fatal Outcome; Heterocyclic Compounds; Humans; Immunologic Deficiency Syndromes; Male; Middle Aged; Neoplasms, Squamous Cell; Phenotype; Primary Immunodeficiency Diseases; Primary Myelofibrosis; Receptors, CXCR4; Warts	2019
A WHIM satisfactorily addressed. Blood, 2014, Apr-10, Volume: 123, Issue:15 Topics: Benzylamines; Cyclams; Female; Heterocyclic Compounds; Humans; Immunologic Deficiency Syndromes; Male; Primary Immunodeficiency Diseases; Receptors, CXCR4; Warts	2014
AMD3100 is a potent antagonist at CXCR4(R334X) , a hyperfunctional mutant chemokine receptor and cause of WHIM syndrome. Journal of cellular and molecular medicine, 2011, Volume: 15, Issue:10 Topics: Adult; Animals; Benzylamines; CHO Cells; Cricetinae; Cyclams; Female; Flow Cytometry; Gene Expression Regulation; Heterocyclic Compounds; Humans; Immunologic Deficiency Syndromes; K562 Cells; Primary Immunodeficiency Diseases; Receptors, CXCR4; Warts	2011
Released on a WHIM. Blood, 2011, Nov-03, Volume: 118, Issue:18 Topics: Benzylamines; Cyclams; Female; Granulocyte Precursor Cells; Heterocyclic Compounds; Humans; Immunologic Deficiency Syndromes; Lymphopenia; Male; Primary Immunodeficiency Diseases; Warts	2011