plerixafor has been researched along with Acute Lymphoid Leukemia in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 12 (70.59) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Fang, MH; Gao, SJ; Gu, XY; Hu, Z; Meng, XD; Su, L; Wang, X; Yang, YG; Zou, J | 1 |
| Hu, Z; Su, L; Yang, YG | 1 |
| Absalon, MJ; Ahmed, A; August, K; Baker, SD; Boklan, J; Brown, PA; Cooper, TM; Gore, L; Li, L; Macy, ME; Magoon, D; Narendran, A; Pollard, J; Sison, EAR; Trippett, T | 1 |
| Chen, M; Hu, Z; Jin, CH; Li, W; Li, Y; Mapara, MY; Xia, J; Yang, YG | 1 |
| Arras, M; Caocci, G; Floris, R; Greco, M; La Nasa, G; Ledda, A; Sanna, M; Vacca, A | 1 |
| Brown, P; Magoon, D; McIntyre, E; Sison, EA | 1 |
| Baratti, MO; Bigarella, CL; de Melo Campos, P; Favaro, P; Longhini, AL; Melo, RCC; Saad, ST; Traina, F | 1 |
| Bonferroni, M; Borra, A; Castellino, C; Celeghini, I; Di Marco, C; Fiore, F; Gallamini, A; Ghiglia, A; Grasso, M; Marenchino, D; Mattei, D; Mordini, N; Rapezzi, D; Sorasio, R; Strola, G | 1 |
| Annesley, CE; Brown, P; Li, L; Magoon, D; Rau, RE; Sison, EA; Small, D | 1 |
| Assanelli, A; Bellio, L; Ciceri, F; Coppola, M; Corti, C; De Freitas, T; Gattillo, S; Malabarba, L; Malato, S; Marktel, S; Milani, R; Rizzo, L | 1 |
| Biondi, A; Borga, C; Cazzaniga, G; Grassi, F; Indraccolo, S; Jost, TR; Omodho, L; Perruzza, L; Radaelli, E; Romagnani, A; Te Kronnie, G; Thelen, M | 1 |
| Dubeykovskaya, Z; Dubeykovskiy, A; Solal-Cohen, J; Wang, TC | 1 |
| Baraz, R; Bendall, LJ; Bradstock, KF; Dela Pena, A; Juarez, JG; Thien, M | 1 |
| Groffen, J; Heisterkamp, N; Lim, M; Parameswaran, R; Yu, M | 1 |
| Adachi, S; Fujino, H; Heike, T; Hiramatsu, H; Ishikawa, F; Ito, M; Kato, I; Morita, M; Nakahata, T; Nishinaka, Y; Niwa, A; Saito, MK; Umeda, K | 1 |
| Basnett, J; Bendall, LJ; Bradstock, KF; Dela Pena, A; Juarez, JG; Liedtke, F; Welschinger, R | 1 |
| Bendall, LJ; Bradstock, KF; Gottlieb, DJ; Juarez, J | 1 |
1 review(s) available for plerixafor and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Role of CXCR4 in the progression and therapy of acute leukaemia.
Topics: Benzylamines; Chemokine CXCL12; Cyclams; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Receptors, CXCR4; Signal Transduction; Small Molecule Libraries | 2021 |
3 trial(s) available for plerixafor and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
A phase 1 study of the CXCR4 antagonist plerixafor in combination with high-dose cytarabine and etoposide in children with relapsed or refractory acute leukemias or myelodysplastic syndrome: A Pediatric Oncology Experimental Therapeutics Investigators' Co
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Benzylamines; Child; Child, Preschool; Cyclams; Cytarabine; Etoposide; Female; Heterocyclic Compounds; Humans; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, CXCR4; Treatment Outcome; Young Adult | 2017 |
Peripheral blood CD34+ percentage at hematological recovery after chemotherapy is a good early predictor of harvest: a single-center experience.
Topics: Adolescent; Adult; Aged; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Benzylamines; Biomarkers; Cyclams; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Heterocyclic Compounds; Hodgkin Disease; Humans; Leukocyte Count; Lymphoma, Non-Hodgkin; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Time Factors; Transplantation, Autologous | 2014 |
Plerixafor on demand in ten healthy family donors as a rescue strategy to achieve an adequate graft for stem cell transplantation.
Topics: Adult; Aged; Allografts; Antigens, CD34; Benzylamines; Blood Cell Count; Carcinoma, Renal Cell; Colony-Forming Units Assay; Cyclams; Drug Synergism; Female; Graft Survival; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells; Heterocyclic Compounds; Humans; Kidney Neoplasms; Lenograstim; Leukapheresis; Leukemia, Myeloid, Acute; Living Donors; Male; Middle Aged; Pain; Parents; Peripheral Blood Stem Cell Transplantation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins; Siblings; Treatment Outcome | 2015 |
13 other study(ies) available for plerixafor and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Posttransplant blockade of CXCR4 improves leukemia complete remission rates and donor stem cell engraftment without aggravating GVHD.
Topics: Animals; Benzylamines; Chimerism; Cyclams; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred NOD; Postoperative Complications; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, CXCR4; Stem Cells; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome | 2021 |
CXCR4 blockade improves leukemia eradication by allogeneic lymphocyte infusion.
Topics: Animals; Benzylamines; Cell Line, Tumor; Cyclams; Heterocyclic Compounds; Heterografts; Humans; Immunotherapy, Adoptive; Lymphocyte Transfusion; Mice; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, CXCR4; Transplantation, Homologous | 2018 |
Successful and safe stem cell mobilization using plerixafor in a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia.
Topics: Antigens, CD34; Benzylamines; Cyclams; Female; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Heterocyclic Compounds; Humans; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, CXCR4; Reproducibility of Results | 2014 |
Dynamic chemotherapy-induced upregulation of CXCR4 expression: a mechanism of therapeutic resistance in pediatric AML.
Topics: Antineoplastic Agents; Apoptosis; Benzylamines; Cell Line, Tumor; Cell Movement; Chemokine CXCL12; Chemotaxis; Child; Cyclams; Drug Resistance, Neoplasm; Gene Expression Regulation, Leukemic; Heterocyclic Compounds; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, CXCR4; Stromal Cells; Up-Regulation | 2013 |
CXCR7 is highly expressed in acute lymphoblastic leukemia and potentiates CXCR4 response to CXCL12.
Topics: Adult; Aged; Aged, 80 and over; Benzylamines; Blotting, Western; Bone Marrow; Cell Line, Tumor; Cell Movement; Chemokine CXCL12; Cyclams; Female; Flow Cytometry; Gene Expression Regulation, Leukemic; Heterocyclic Compounds; Humans; Jurkat Cells; K562 Cells; Leukocytes; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, CXCR; Receptors, CXCR4; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; U937 Cells; Young Adult | 2014 |
Plerixafor as a chemosensitizing agent in pediatric acute lymphoblastic leukemia: efficacy and potential mechanisms of resistance to CXCR4 inhibition.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzylamines; Cell Adhesion Molecules; Cell Line, Tumor; Chemokine CXCL12; Chemotaxis; Coculture Techniques; Cyclams; Cytarabine; Heterocyclic Compounds; Heterografts; Humans; Infant; Infant, Newborn; Integrin alpha4beta1; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, CXCR; Receptors, CXCR4; Up-Regulation | 2014 |
Role of CXCR4-mediated bone marrow colonization in CNS infiltration by T cell acute lymphoblastic leukemia.
Topics: Adolescent; Animals; Benzylamines; Bone Marrow; Cell Line, Transformed; Cell Line, Tumor; Central Nervous System; Child; Child, Preschool; Cyclams; Female; Hematopoietic Stem Cells; Heterocyclic Compounds; Humans; Liver; Male; Meninges; Mice; Phenotype; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Chemokine; Receptors, CXCR4; Receptors, Notch; RNA, Messenger; Stem Cells; Xenograft Model Antitumor Assays | 2016 |
Secreted trefoil factor 2 activates the CXCR4 receptor in epithelial and lymphocytic cancer cell lines.
Topics: Animals; Anti-HIV Agents; Benzylamines; Calcium Signaling; Chemokine CXCL12; Cyclams; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds; Humans; Jurkat Cells; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Mucins; Muscle Proteins; Neoplasm Proteins; Neoplasms, Glandular and Epithelial; NIH 3T3 Cells; Peptides; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, CXCR4; Trefoil Factor-2 | 2009 |
CXCR4 mediates the homing of B cell progenitor acute lymphoblastic leukaemia cells to the bone marrow via activation of p38MAPK.
Topics: Animals; B-Lymphocytes; Benzylamines; Bone Marrow; Cell Line, Tumor; Chemokine CXCL12; Chemotaxis, Leukocyte; Chromones; Cyclams; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Heterocyclic Compounds; Humans; Imidazoles; Mice; Mice, Inbred NOD; Mice, SCID; Morpholines; Neoplastic Stem Cells; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Binding; Receptors, CXCR4 | 2009 |
Combination of drug therapy in acute lymphoblastic leukemia with a CXCR4 antagonist.
Topics: Aminoquinolines; Animals; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Benzylamines; Butylamines; Cell Movement; Chemokine CXCL12; Cyclams; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Humans; Mice; Mice, Inbred C57BL; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, CXCR4; Signal Transduction; Vincristine | 2011 |
Identification of hepatic niche harboring human acute lymphoblastic leukemic cells via the SDF-1/CXCR4 axis.
Topics: Animals; Anti-HIV Agents; Benzylamines; Blotting, Western; Bone Marrow; Cell Adhesion; Cell Cycle; Cell Movement; Cell Proliferation; Chemokine CXCL12; Child; Child, Preschool; Cyclams; Female; Flow Cytometry; Hepatocytes; Heterocyclic Compounds; Humans; Infant; Liver; Male; Mice; Mice, Inbred NOD; Mice, SCID; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, CXCR4; Transplantation, Heterologous; Tumor Cells, Cultured | 2011 |
Plerixafor (AMD3100) induces prolonged mobilization of acute lymphoblastic leukemia cells and increases the proportion of cycling cells in the blood in mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Benzylamines; Cell Cycle; Cells, Cultured; Chemokine CXCL12; Chemotaxis; Cyclams; Drug Synergism; Flow Cytometry; Hematopoiesis; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells; Heterocyclic Compounds; Humans; Kaplan-Meier Estimate; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, SCID; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, CXCR4; Tumor Cells, Cultured; Vincristine; Xenograft Model Antitumor Assays | 2013 |
Effects of inhibitors of the chemokine receptor CXCR4 on acute lymphoblastic leukemia cells in vitro.
Topics: Antineoplastic Agents; Benzylamines; Cell Division; Chemokine CXCL12; Chemokines, CXC; Chemotaxis; Coculture Techniques; Cyclams; Dexamethasone; Drug Synergism; Heterocyclic Compounds; Humans; Oligopeptides; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, CXCR4; Stromal Cells; Vincristine | 2003 |