pleconaril has been researched along with Meningitis, Viral in 6 studies
WIN 63843: structure given in first source
Meningitis, Viral: Viral infections of the leptomeninges and subarachnoid space. TOGAVIRIDAE INFECTIONS; FLAVIVIRIDAE INFECTIONS; RUBELLA; BUNYAVIRIDAE INFECTIONS; ORBIVIRUS infections; PICORNAVIRIDAE INFECTIONS; ORTHOMYXOVIRIDAE INFECTIONS; RHABDOVIRIDAE INFECTIONS; ARENAVIRIDAE INFECTIONS; HERPESVIRIDAE INFECTIONS; ADENOVIRIDAE INFECTIONS; JC VIRUS infections; and RETROVIRIDAE INFECTIONS may cause this form of meningitis. Clinical manifestations include fever, headache, neck pain, vomiting, PHOTOPHOBIA, and signs of meningeal irritation. (From Joynt, Clinical Neurology, 1996, Ch26, pp1-3)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pleconaril was well-tolerated, although twice as many adverse events occurred per subject in the pleconaril group." | 2.71 | Double blind placebo-controlled trial of pleconaril in infants with enterovirus meningitis. ( Abzug, MJ; Blount, S; Bradley, J; Capparelli, EV; Cloud, G; Kimberlin, DW; Lakeman, F; Lepow, M; Mani, C; Powell, D; Romero, J; Sánchez, PJ; Whitley, RJ, 2003) |
| "New developments in rapid diagnosis of enterovirus infections using polymerase chain reaction (PCR) positively affect patient management and have the potential to reduce the healthcare impact of enterovirus infection." | 2.41 | Enterovirus infections: diagnosis and treatment. ( Sawyer, MH, 2002) |
| "Enterovirus infections are common in both children and adults and range from benign short-lived febrile illnesses to life-threatening infections." | 2.41 | Enterovirus infections: diagnosis and treatment. ( Sawyer, MH, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sawyer, MH | 3 |
| Abzug, MJ | 1 |
| Cloud, G | 1 |
| Bradley, J | 1 |
| Sánchez, PJ | 1 |
| Romero, J | 1 |
| Powell, D | 1 |
| Lepow, M | 1 |
| Mani, C | 1 |
| Capparelli, EV | 1 |
| Blount, S | 1 |
| Lakeman, F | 1 |
| Whitley, RJ | 2 |
| Kimberlin, DW | 1 |
| Desmond, RA | 1 |
| Accortt, NA | 1 |
| Talley, L | 1 |
| Villano, SA | 1 |
| Soong, SJ | 1 |
| Rogers, JM | 1 |
| Diana, GD | 1 |
| McKinlay, MA | 1 |
4 reviews available for pleconaril and Meningitis, Viral
| Article | Year |
|---|---|
Enterovirus infections: diagnosis and treatment.
Topics: Adult; Antiviral Agents; Child; Clinical Trials as Topic; Enterovirus Infections; Humans; Meningitis | 2002 |
Pleconaril. A broad spectrum antipicornaviral agent.
Topics: Antiviral Agents; Enterovirus; Humans; Meningitis, Viral; Oxadiazoles; Oxazoles; Picornaviridae Infe | 1999 |
Enterovirus infections: diagnosis and treatment.
Topics: Antiviral Agents; Child; Cost of Illness; Enterovirus; Enterovirus Infections; Humans; Meningitis, V | 1999 |
Enterovirus infections: diagnosis and treatment.
Topics: Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Enterovirus Infections; Female; Humans | 2001 |
2 trials available for pleconaril and Meningitis, Viral
| Article | Year |
|---|---|
Double blind placebo-controlled trial of pleconaril in infants with enterovirus meningitis.
Topics: Administration, Oral; Biological Availability; Dose-Response Relationship, Drug; Double-Blind Method | 2003 |
Enteroviral meningitis: natural history and outcome of pleconaril therapy.
Topics: Adult; Antiviral Agents; Double-Blind Method; Enterovirus Infections; Female; Headache; Humans; Male | 2006 |