pleconaril has been researched along with Infections, Respiratory in 4 studies
WIN 63843: structure given in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pleconaril was generally well tolerated; the liquid formulation caused gastrointestinal disturbance in all groups (diarrhoea 10-14%, nausea 5-9%, abdominal discomfort 6-8%), and tablets were associated with a greater incidence of nausea (3% for placebo versus 7% for pleconaril, P = 0." | 2.70 | Oral pleconaril treatment of picornavirus-associated viral respiratory illness in adults: efficacy and tolerability in phase II clinical trials. ( Blatter, MM; Coats, T; Hassman, HA; Hayden, FG; Kim, K; Liu, S; Zhang, B, 2002) |
| "Conversely, trials conducted in cases of upper respiratory tract infections and meningitis caused by enteroviruses have shown modest results." | 1.30 | [New antivirals for respiratory tract viruses]. ( Le Moing, V, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, L | 1 |
| Meijer, A | 1 |
| Froeyen, M | 1 |
| Zhang, L | 1 |
| Thibaut, HJ | 1 |
| Baggen, J | 1 |
| George, S | 1 |
| Vernachio, J | 1 |
| van Kuppeveld, FJ | 1 |
| Leyssen, P | 1 |
| Hilgenfeld, R | 1 |
| Neyts, J | 1 |
| Delang, L | 1 |
| Le Moing, V | 1 |
| Schiff, GM | 1 |
| Sherwood, JR | 1 |
| Hayden, FG | 1 |
| Coats, T | 1 |
| Kim, K | 1 |
| Hassman, HA | 1 |
| Blatter, MM | 1 |
| Zhang, B | 1 |
| Liu, S | 1 |
2 trials available for pleconaril and Infections, Respiratory
| Article | Year |
|---|---|
Clinical activity of pleconaril in an experimentally induced coxsackievirus A21 respiratory infection.
Topics: Adolescent; Adult; Antibodies, Viral; Antiviral Agents; Coxsackievirus Infections; Enterovirus; Fema | 2000 |
Oral pleconaril treatment of picornavirus-associated viral respiratory illness in adults: efficacy and tolerability in phase II clinical trials.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Double-Blind Met | 2002 |
2 other studies available for pleconaril and Infections, Respiratory
| Article | Year |
|---|---|
Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68.
Topics: Antiviral Agents; Drug Resistance, Viral; Enterovirus D, Human; Enterovirus Infections; Humans; Micr | 2015 |
[New antivirals for respiratory tract viruses].
Topics: Antiviral Agents; Drug Approval; France; Guanidines; Humans; Influenza, Human; Neuraminidase; Oxadia | 1999 |