pleconaril has been researched along with Chronic Disease in 3 studies
WIN 63843: structure given in first source
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pleconaril is a novel compound that integrates into the capsid of picornaviruses, including enteroviruses and rhinoviruses, preventing the virus from attaching to cellular receptors and uncoating to release RNA into the cell." | 6.70 | Treatment of potentially life-threatening enterovirus infections with pleconaril. ( Rotbart, HA; Webster, AD, 2001) |
| "Pleconaril is a novel compound that integrates into the capsid of picornaviruses, including enteroviruses and rhinoviruses, preventing the virus from attaching to cellular receptors and uncoating to release RNA into the cell." | 2.70 | Treatment of potentially life-threatening enterovirus infections with pleconaril. ( Rotbart, HA; Webster, AD, 2001) |
| "Pleconaril is an antiviral agent with in vitro activity against HEVs that has been used in the treatment of HEV infections." | 1.38 | Pleconaril revisited: clinical course of chronic enteroviral meningoencephalitis after treatment correlates with in vitro susceptibility. ( Benschop, KS; Koen, G; Kuijpers, TW; van den Broek, PJ; Vossen, AC; Wierenga, PC; Wildenbeest, JG; Wolthers, KC, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van de Ven, AA | 1 |
| Douma, JW | 1 |
| Rademaker, C | 1 |
| van Loon, AM | 1 |
| Wensing, AM | 1 |
| Boelens, JJ | 1 |
| Sanders, EA | 1 |
| van Montfrans, JM | 1 |
| Wildenbeest, JG | 1 |
| van den Broek, PJ | 1 |
| Benschop, KS | 1 |
| Koen, G | 1 |
| Wierenga, PC | 1 |
| Vossen, AC | 1 |
| Kuijpers, TW | 1 |
| Wolthers, KC | 1 |
| Rotbart, HA | 1 |
| Webster, AD | 1 |
1 trial available for pleconaril and Chronic Disease
| Article | Year |
|---|---|
Treatment of potentially life-threatening enterovirus infections with pleconaril.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Child; Child, Preschool; Chronic Disease; Enterovirus; En | 2001 |
2 other studies available for pleconaril and Chronic Disease
| Article | Year |
|---|---|
Pleconaril-resistant chronic parechovirus-associated enteropathy in agammaglobulinaemia.
Topics: Adolescent; Agammaglobulinemia; Antiviral Agents; Caliciviridae Infections; Chronic Disease; Drug Re | 2011 |
Pleconaril revisited: clinical course of chronic enteroviral meningoencephalitis after treatment correlates with in vitro susceptibility.
Topics: Antiviral Agents; Cerebrospinal Fluid; Child; Chronic Disease; Drug Resistance, Viral; Enterovirus; | 2012 |