pleconaril has been researched along with Autoimmune Diabetes in 5 studies
WIN 63843: structure given in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| " Median effective dose was interpolated from the triplicated experiments and the dose-response curves were generated for each drug-virus combination." | 1.56 | A preclinical assessment to repurpose drugs to target type 1 diabetes-associated type B coxsackieviruses. ( Honkimaa, A; Hyöty, H; Sioofy-Khojine, AB, 2020) |
| "Pleconaril treatment reduced the beta-cells' insulin secretion in response to glucose stimulation in some experiments and induced slight morphological changes to the islets compared to untreated controls." | 1.34 | Antiviral treatment of Coxsackie B virus infection in human pancreatic islets. ( Berg, AK; Frisk, G; Korsgren, O; Olsson, A, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Krogvold, L | 1 |
| Mynarek, IM | 1 |
| Ponzi, E | 1 |
| Mørk, FB | 1 |
| Hessel, TW | 1 |
| Roald, T | 1 |
| Lindblom, N | 1 |
| Westman, J | 1 |
| Barker, P | 1 |
| Hyöty, H | 2 |
| Ludvigsson, J | 1 |
| Hanssen, KF | 1 |
| Johannesen, J | 1 |
| Dahl-Jørgensen, K | 1 |
| Sioofy-Khojine, AB | 1 |
| Honkimaa, A | 1 |
| Niklasson, B | 2 |
| Klitz, W | 2 |
| Juntti-Berggren, L | 2 |
| Berggren, PO | 2 |
| Lindquist, L | 1 |
| Holmberg, R | 1 |
| Blixt, M | 1 |
| Berg, AK | 1 |
| Olsson, A | 1 |
| Korsgren, O | 1 |
| Frisk, G | 1 |
1 trial available for pleconaril and Autoimmune Diabetes
| Article | Year |
|---|---|
Pleconaril and ribavirin in new-onset type 1 diabetes: a phase 2 randomized trial.
Topics: Adolescent; Antiviral Agents; C-Peptide; Child; Diabetes Mellitus, Type 1; Double-Blind Method; Huma | 2023 |
4 other studies available for pleconaril and Autoimmune Diabetes
| Article | Year |
|---|---|
A preclinical assessment to repurpose drugs to target type 1 diabetes-associated type B coxsackieviruses.
Topics: A549 Cells; Amides; Antiviral Agents; Azithromycin; Benzimidazoles; Coxsackievirus Infections; Diabe | 2020 |
Effectiveness of Antivirals in a Type 1 Diabetes Model and the Move Toward Human Trials.
Topics: Adult; Alkynes; Animals; Antiviral Agents; Benzoxazines; Cyclopropanes; Diabetes Mellitus, Type 1; H | 2020 |
Antiviral treatments reduce severity of diabetes in Ljungan virus-infected CD-1 mice and delay onset in diabetes-prone BB rats.
Topics: Animals; Antibodies, Viral; Antiviral Agents; Diabetes Mellitus, Type 1; Drug Therapy, Combination; | 2009 |
Antiviral treatment of Coxsackie B virus infection in human pancreatic islets.
Topics: Antiviral Agents; Cells, Cultured; Coxsackievirus Infections; Cytopathogenic Effect, Viral; Diabetes | 2007 |