Page last updated: 2024-09-05

pld118 and Candidiasis

pld118 has been researched along with Candidiasis in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bacher, J; Groll, AH; Kelaher, AM; Mickiene, D; Petraitiene, R; Petraitis, V; Sarafandi, AA; Sein, T; Walsh, TJ2
Ergovic, G; Galic, T; Geschke, U; Hasenoehrl, A; Marsic, N; Mittendorf, J; Schmidt, A; Schoenfeld, W; Skerlev, M1

Other Studies

3 other study(ies) available for pld118 and Candidiasis

ArticleYear
Efficacy of PLD-118, a novel inhibitor of candida isoleucyl-tRNA synthetase, against experimental oropharyngeal and esophageal candidiasis caused by fluconazole-resistant C. albicans.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:10

    Topics: Animals; Antifungal Agents; Area Under Curve; Candida albicans; Candidiasis; Candidiasis, Oral; Cycloleucine; Drug Resistance, Fungal; Enzyme Inhibitors; Esophageal Diseases; Female; Fluconazole; Half-Life; Immunosuppression Therapy; Isoleucine-tRNA Ligase; Rabbits

2004
Efficacy, plasma pharmacokinetics, and safety of icofungipen, an inhibitor of Candida isoleucyl-tRNA synthetase, in treatment of experimental disseminated candidiasis in persistently neutropenic rabbits.
    Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:5

    Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis; Culture Media; Cycloleucine; Female; Immunosuppression Therapy; Isoleucine-tRNA Ligase; Kidney; Liver; Neutropenia; Rabbits; Spleen

2005
In vitro activity and in vivo efficacy of icofungipen (PLD-118), a novel oral antifungal agent, against the pathogenic yeast Candida albicans.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:9

    Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis; Cycloleucine; Drug Interactions; Hydrogen-Ion Concentration; Isoleucine; Male; Mice; Microbial Sensitivity Tests; Rats; Rats, Sprague-Dawley; Temperature

2006