platycodin d has been researched along with Liver Neoplasms in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, XW; Lei, J; Long, MY; Wang, FJ; Zhao, J | 1 |
| Chen, MC; Chen, RJ; Day, CH; Hsu, WC; Huang, CY; Li, CC; Padma, VV; Ramesh, S; Shibu, MA; Tseng, YC; Wang, TF | 1 |
| Du, X; Qin, H; Wang, R; Zhang, Y | 1 |
| Chen, XP; Li, T; Lu, JJ; Wang, YT; Wu, GS; Xu, WS | 1 |
| Chang, LL; Chen, XP; Chen, Y; Li, T; Lu, JJ; Tang, ZH; Wang, YF; Wang, YT; Wu, GS; Xu, WS; Zhu, H | 1 |
| Chen, YF; Dong, YT; Li, T; Lu, DZ; Lu, JJ; Tang, ZH; Yang, Z; Zhang, JR | 1 |
| Chen, XP; Chen, Y; Leung, CH; Li, T; Lu, JJ; Ma, DL; Tang, ZH; Wang, YF; Wang, YT; Xu, XH | 1 |
| Li, W; Liu, Y; Tang, S; Tian, YH; Wang, YP; Wang, Z; Zhang, J | 1 |
8 other study(ies) available for platycodin d and Liver Neoplasms
| Article | Year |
|---|---|
In addition to its endosomal escape effect, platycodin D also synergizes with ribosomal inactivation protein to induce apoptosis in hepatoma cells through AKT and MAPK signaling pathways.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Endosomes; Humans; Liver Neoplasms; MAP Kinase Signaling System; Proto-Oncogene Proteins c-akt; Ribosomal Proteins; Saponins; Signal Transduction; Triterpenes | 2022 |
Platycodin D reverses histone deacetylase inhibitor resistance in hepatocellular carcinoma cells by repressing ERK1/2-mediated cofilin-1 phosphorylation.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cofilin 1; Cofilin 2; Drug Resistance, Neoplasm; Histone Deacetylase Inhibitors; Humans; Liver Neoplasms; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondria; Phosphorylation; Saponins; Triterpenes | 2021 |
Platycodin D, a triterpenoid saponin from Platycodon grandiflorum, induces G2/M arrest and apoptosis in human hepatoma HepG2 cells by modulating the PI3K/Akt pathway.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Elafin; G2 Phase Cell Cycle Checkpoints; Hep G2 Cells; Humans; Liver Neoplasms; Platycodon; Proto-Oncogene Proteins c-akt; Saponins; Signal Transduction; Triterpenes | 2014 |
Platycodin D induces apoptosis, and inhibits adhesion, migration and invasion in HepG2 hepatocellular carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Hep G2 Cells; Humans; Inhibitor of Apoptosis Proteins; Liver Neoplasms; Medicine, Chinese Traditional; Neoplasm Invasiveness; Plant Extracts; Poly(ADP-ribose) Polymerases; Saponins; Survivin; Tetradecanoylphorbol Acetate; Triterpenes; Up-Regulation | 2014 |
Platycodin D triggers autophagy through activation of extracellular signal-regulated kinase in hepatocellular carcinoma HepG2 cells.
Topics: Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Chloroquine; Extracellular Signal-Regulated MAP Kinases; Humans; Liver Neoplasms; Macrolides; Saponins; Triterpenes | 2015 |
Proteomic analysis of hepatocellular carcinoma HepG2 cells treated with platycodin D.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Campanulaceae; Carcinoma, Hepatocellular; Cell Proliferation; Cell Survival; Hep G2 Cells; Humans; Liver Neoplasms; Phytotherapy; Plant Extracts; Prohibitins; Proteome; Proteomics; Saponins; Triterpenes; Up-Regulation | 2015 |
Platycodin D induces apoptosis and triggers ERK- and JNK-mediated autophagy in human hepatocellular carcinoma BEL-7402 cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Female; Humans; Liver; Liver Neoplasms; MAP Kinase Signaling System; Mice, Inbred BALB C; Mice, Nude; Platycodon; Saponins; Triterpenes | 2015 |
Platycodin D exerts anti-tumor efficacy in H22 tumor-bearing mice via improving immune function and inducing apoptosis.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytokines; Dose-Response Relationship, Drug; Immunologic Factors; Liver Neoplasms; Male; Mice, Inbred ICR; Proto-Oncogene Proteins c-bcl-2; Saponins; Signal Transduction; Time Factors; Triterpenes; Tumor Burden; Vascular Endothelial Growth Factor A | 2016 |