Page last updated: 2024-08-22

platinum and Neoplasms

platinum has been researched along with Neoplasms in 466 studies

Research

Studies (466)

TimeframeStudies, this research(%)All Research%
pre-199050 (10.73)18.7374
1990's32 (6.87)18.2507
2000's39 (8.37)29.6817
2010's168 (36.05)24.3611
2020's177 (37.98)2.80

Authors

AuthorsStudies
Liu, K; Liu, X; Piao, Y; Shen, Y; Tang, J; Wang, G; Xiang, J; Xu, H; Zhou, Z1
Arsenijević, A; Arsenijević, N; Milovanović, J; Milovanović, M; Rajković, S; Vasić, I; Živković, MD1
Dong, Q; Li, J; Li, Z; Liu, D; Liu, H; Wang, X; Zhang, J; Zhao, G; Zhou, X1
Birrer, MJ; Calinawan, AP; Huang, D; Lin, C; Paulovich, AG; Savage, SR; Starr, TK; Wang, P; Zhang, B1
Busto, N; Espino, G; Fernández, D; Fernández-Pampín, N; García, B; Gil, T; Vaquero, M1
Adamakis, I; Anastasiou, I; Bamias, A; Boulouta, A; Constantinides, CA; Dedes, N; Deliveliotis, C; Dellis, A; Dimopoulos, MA; Ferakis, N; Fragkoulis, C; Gavalas, N; Kostouros, E; Koutsoukos, K; Mitropoulos, D; Mitsogiannis, I; Ntoumas, K; Pagoni, S; Papatsoris, A; Skolarikos, A; Stravodimos, K; Tzannis, K; Zakopoulou, R1
Dang, S; Singh, S; Sohi, H; Yadav, A1
Cai, L; Chen, H; Guo, Z; Jin, S; Song, D; Tan, Y; Wang, X; Yang, T; Zhang, J1
Espino, J; Estirado, S; Fernández-Delgado, E; Luna-Giles, F; Pariente, JA; Rodríguez Moratinos, AB; Viñuelas-Zahínos, E1
Han, R; Hao, Y; Hu, D; Li, H; Li, Y; Liu, Q; Ming, Y; Pan, M; Peng, J; Qian, Z; Yang, Y; Yu, Y; Yuan, L1
Chen, T; Fu, Y; Han, G; Li, X; Zhang, R1
Dai, Z; Hu, Z; Kou, Y; Sun, Y; Tang, W; Wei, Q; Zhang, H; Zheng, X1
Chen, SP; Liao, FH; Lin, SY; Lin, WJ; Wu, TH; Yao, CN; Yeh, LC1
Chao, Y; Gong, Y; Liu, Z; Shao, M; Tian, L; Wei, T; Zhu, Y1
Chen, Z; Li, S; Li, T; Liu, G; Liu, S; Wu, T; Wu, Y1
Dong, H; Gong, C; Meng, X; Shi, J; Wu, P; Yang, Z; Zhao, J1
Gao, X; Xu, C; Yao, Q; Zhang, C1
Drake, HF; Huang, Y; Jin, Y; Li, J; Li, Y; Yan, TH; Zhao, R; Zhong, H; Zhou, HC; Zhu, Y1
Chen, S; Deng, Z; Liu, G; Shi, J; Wang, N; Wang, Z; Yao, H; Zhou, J; Zhu, G1
Banerjee, S1
He, X; Huang, Y; Wang, Z; Yu, J; Zhang, Q; Zhou, D1
Gadre, S; Kamisetti, RT; Patra, M; Vaidya, SP1
Abrams, G; Alfaro, E; Cheung, S; Conley, YP; Cooper, B; Henderson-Sabes, J; Kober, KM; Levine, JD; Miaskowski, C; Paul, SM; Quinn, M; Snowberg, K; Topp, K1
Ge, X; Huo, H; Li, Q; Lin, H; Liu, L; Mu, J; Song, J; Su, L; Wu, Y; Zhang, X; Zheng, L1
Fu, T; Li, Y; Liu, Y; Long, W; Stang, PJ; Tan, W; Yan, Y; Zhang, P; Zhao, Z; Zhou, Z1
Alhumaydhi, FA; Alqahtani, A; Alruwaili, AS; Alshamrani, M; Hassanian, AA; Ibrahim, MM; Khan, S1
Huang, J; Kang, Y; Li, Y; Wang, J; Xu, Z; Xue, P; Zhang, L1
Dong, L; Fang, H; Guo, Z; Han, Z; Shi, X; Wang, X; Wang, Y; Yuan, H; Zhu, Z1
Chen, D; Hu, H; Li, D; Li, K; Qiao, M; Sun, X; Xiu, J; Yang, C; Zhang, J; Zhao, X1
Am Zehnhoff-Dinnesen, A; Ansari, M; Kompis, M; Kuehni, CE; Mader, L; Parfitt, R; Sláma, T; Strebel, S; von der Weid, NX; Waespe, N; Weiss, A1
Chadha, S; Dillard, LK; Fullerton, AM; Lopez-Perez, L; Martinez, RX; McMahon, CM1
Fang, Y; Huang, H; Kang, Y; Luo, M; Wu, J; You, X; Zhang, R; Zhang, X1
Liu, X; Piao, Y; Shao, S; Shen, Y; Tang, J; Xiang, J; Xie, T; Zhang, Y; Zhou, Q; Zhou, Z1
Bender, DP; Brady, MF; Burger, RA; Cella, D; Copeland, LJ; Dewdney, SB; DiSaia, PJ; Glaser, GE; Guntupalli, S; Huang, HQ; Lele, SB; Lowery, WJ; Mannel, RS; Miller, DS; Morris, RT; O'Malley, DM; Rodgers, WH; Spirtos, NM; Street, DG; Tewari, KS; Ueland, FR1
Gu, Z; Guo, K; Jiang, G; Liu, C; Lv, M; Wang, C; Wang, H; Xie, J; Xu, Q; Yang, Z; Yong, Y; Zhang, Y1
Chou, T; Gallaro, C; Halloran, M; Hu, W; Hu, X; Liang, L; Ren, L; Sun, J; Wang, H; Wang, J; Wang, Y; Zhang, B; Zhang, Q1
Banskota, S; Bhattacharyya, J; Borgnia, MJ; Chilkoti, A; Deshpande, S; Dzuricky, M; Fan, P; Kim, S; Li, X; Liu, J; Raman, A; Saha, S; Schaal, JL; Sharma, K; Spasojevic, I; Zakharov, N1
Chen, F; Li, Y; Lin, X; Qiu, H; Stang, PJ; Wang, H; Yin, S; Yu, X1
Ali, EMM; Alomari, MM; Babgi, BA; Davaasuren, B; El-Bendary, MM; Jaremko, M; Saleh, TS1
Abrams, G; Alfaro, E; Cheung, S; Conley, Y; Cooper, B; Henderson-Sabes, J; Levine, J; Mastick, J; Miaskowski, C; Paul, S; Quinn, M; Snowberg, K; Wallhagen, M1
Balakrishnan, AJ; Janardhanan, P; Pilankatta, R; Somasundaran, AK1
Alessio, E; Burckel, P; Gandioso, A; Gasser, G; Vidal, A1
Chen, W; Deng, X; Hu, H; Li, J; Liu, W; Song, Q; Xing, X; Yang, W; Zhang, Y1
Hao, L; Li, ZY; Ling, YY; Liu, LY; Liu, W; Mao, ZW; Tan, CP; Wang, WJ; Xia, XY; Zhang, H1
Bonet-Aleta, J; Garcia-Peiro, JI; Hueso, JL; Santamaria, J1
Guo, Y; Guo, Z; Han, Q; Hu, J; Hu, X; Jin, S; Song, D; Wang, X; Yang, T; Zhao, J1
Ding, Y; Liu, B; Lu, L; Zheng, P; Zhou, C1
Denis, C; Jego, B; Kereselidze, D; Lacombe, S; Porcel, E; Remita, H; Savina, F; Tran, VL; Truillet, C; Yang, X1
Cao, Y; Chen, Y; Fang, D; Gao, J; Hu, B; Li, T; Liu, J; Ma, J; Ma, R; Niu, H; Su, S; Sun, H; Wang, C; Wang, J; Wang, PG; Xie, S; Zhang, P; Zhang, W1
Chen, Z; Liu, S; Su, J; Wang, Z; Wu, Y; Xia, H; Yao, Z1
Deng, H; Li, C; Pang, Y; Sun, Y1
Hangan, AC; Lucaciu, RL; Oprean, LS; Sevastre, B1
Chen, Z; Fu, S; Qiao, H; Sun, J; Sun, M; Yu, X; Zhai, Y1
Bär, SI; Herrmann, A; Oberhuber, N; Schleser, SW; Schlotte, L; Schobert, R; Weber, SE1
Deng, Y; Ke, H; Li, M; Li, T; Luo, J; Wang, X; Wang, Y; Yang, H; Yang, T; You, M; Zhang, J1
Duan, QY; Gu, R; Guo, Y; Jia, HR; Li, C; Wu, FG; Zhang, X; Zhu, YX1
Lujan, L; Martín-Duque, P; Martín-Pardillos, A; Sancho-Albero, M; Santamaria, J; Sebastian, V1
Ahmed, R; Attia, M; Hanna, D; Kamal, NM; Oshi, MAM; Rifky, E; Sherief, LM1
Fang, C; Gu, H; Hu, X; Lee, J; Li, F; Ling, D; Ren, J; Sun, H; Zhang, B1
Jia, D; Li, L; Liu, M; Liu, Z; Sun, B; Wang, Q; Wang, Z; Zhang, M; Zhang, N1
Patra, M; Vaidya, SP1
Bian, Y; Cheng, Z; Li, F; Liang, S; Lin, J; Liu, B; Ma, P; Yang, C; Yang, L; Yang, Z; Yuan, M1
Bergamini, A; Bocciolone, L; Candiani, M; Candotti, G; Cioffi, R; De Marzi, P; Galli, F; Mangili, G; Pella, F; Rabaiotti, E1
Heger, Z; Jancik-Prochazkova, A; Michalkova, H; Pumera, M1
Cheng, M; Deng, A; Fan, R; Gou, J; Lin, R; Liu, Y; Luo, L; Qi, B; Sang, R; Wei, G; Yang, L; Zhang, S; Zhao, M1
Akeroyd, MA; Baguley, DM; Pearson, SE; Phillips, OR1
Czeleń, P; Szefler, B1
Ren, T; Xu, K; Yang, F; Zhou, YG1
Gonzalez, S; Gonzalez-Perez, A; Lopez-Bigas, N1
Deng, Q; Gong, Y; Mei, T; Wang, T1
Huang, W; Li, X; Liu, W; Sun, C; Wang, T; Xiong, F; Yao, X1
Bian, J; He, M; Ju, S; Li, J; Li, Q; Luo, X; Sun, M; Wang, Z; Yang, X; Yang, Y; Zhou, Z1
Chiba, N; Endo, S; Shirota, M; Watanabe, G; Yoshino, Y1
Jogadi, W; Zheng, YR1
Banerjee, S; Cui, M; Karges, J; Liang, G; Montesdeoca, N; Sadhukhan, T; Tang, D; Xiao, H; Zhang, H1
Fan, Z; Hou, Z; Huang, L; Li, Y; Meng, J; Su, G; Wang, Q; Wu, F; Yi, X1
Mbugua, SN; Njenga, LW; Odhiambo, RA; Onani, MO1
Chen, Y; Gao, P; Li, N; Li, X; Pan, W; Tang, B; Wei, R1
Aghaei, A; Danafar, H; Gyergyek, S; Likozar, B; Shaterian, M; Šuligoj, A1
Li, S; Liang, H; Xu, G; Yang, F; Yang, T; Zhang, J; Zhang, Z1
Huang, Y; Pan, Y; Qi, Y; Yu, J; Zhang, N; Zhong, T1
Coffetti, G; Facchetti, G; Moraschi, M; Rimoldi, I1
Guo, Y; Kong, L; Li, X; Lu, J; Qin, X; Xu, H; Yang, C; Zhang, R; Zhang, Z; Zhao, S1
Aldrich-Wright, JR; Gilbert, J; Gordon, CP; McGhie, BS; Sakoff, J1
Abdala, AA; Adhikari, R; Bhilkar, P; Chaudhary, RG; Potbhare, AK; Rai, AR; Sharma, R; Singh, RP; Yerpude, ST1
Ji, Z; Wang, P; Wang, Y; Xu, X; Yang, Y; Zhang, H1
Bolland, HR; Boulet, MHC; Hammond, EM; Sedgwick, AC1
Aldrich-Wright, JR; Brabec, V; Kasparkova, J; Kostrhunova, H; Markova, L; McGhie, BS; Novakova, O1
Chakraborty, S; Chhatar, S; Duari, P; Gadre, S; M, M; Mehrotra, M; Panda, TR; Patra, M; Ray, P; Sinha, S; Vaidya, SP1
Chen, S; Chen, X; Deng, Z; Liu, G; Peng, W; Peng, YK; Sun, G; Tse, MK; Wang, L; Wang, Y; Yao, H; Yue, J; Zhang, Y; Zhu, G1
Chen, S; Deng, Z; He, ML; Lei, D; Li, H; Li, YY; Liu, D; Liu, G; Lo, PC; Lu, J; Ou, W; Wang, N; Wang, X; Xu, F; Yang, M; Zhu, G1
Daneshvar, F; Haghighi, H; Salehi, F; Sattarahmady, N; Tamaddon, P; Zahraie, N1
Dokudovskaya, S; Pan, Z; Zhang, H1
Chen, Y; Du, S; Jiang, H; Ren, J; Yang, Y; Zhang, L; Zhu, J1
Avakyan, GG; Chubykina, SV; Tatarinova, MY1
Liu, K; Piao, Y; Shao, S; Shen, Y; Tang, J; Xiang, J; Xu, H; Zhao, Z; Zhou, Z1
Cai, K; Cheng, S; Lei, K; Li, H; Li, J; Zhai, J; Zhou, P1
He, Z; Kamei, KI; Li, G; Li, M; Liu, X; Shi, J; Tian, C; Zheng, S1
Barbanente, A; Brabec, V; Kostrhunová, H; Margiotta, N; Prachařová, J1
Chen, Z; Dong, C; Dong, Q; Dong, W; Dong, Y; Gong, X; Hao, Y; Liu, Y; Shuang, S; Wang, Z; Wu, H; Zhang, L1
Heffeter, P; Kastner, A; Keppler, BK; Kowol, CR; Schueffl, H; Yassemipour, PA1
Cao, Q; Ding, JY; He, J; Liang, BB; Liu, B; Liu, Q; Mao, ZW; Peng, K; Shen, J; Su, XX; Tang, CF; Yao, HG; Zheng, Y1
Li, W; Li, Y; Liu, J; Liu, Y; Shen, H; Yuan, X; Zhang, J1
Bierbach, U; Chen, J; Day, CS; Mancera-Ortiz, IY; Slade, TA; Yao, X; Zhang, S1
Atabi, F; Sabokrouh, A; Sadeghi Motlagh, B1
Ahn, S; Bao, K; Choi, HS; Kang, H; Kim, J; Park, SH; Stiles, WR; Yamashita, A; Zeng, L1
Abro, MI; Jahangir, TM; Khaskheli, MA; Khaskheli, MI; Khokhar, FM; Khokhar, LA; Khuhawar, MY; Muqaddisa, P1
Chen, M; Chen, MY; Cheng, XP; Cui, WX; Zhang, H1
Gao, F; Lu, W; Shi, X; Su, X; Sun, T; Teng, Z; Wang, G; Wang, R; Wu, T1
Han, X; Qin, L; Shao, N; Song, Y; Zhang, P1
Amidani, D; Bisceglie, F; Bonati, B; Buschini, A; Montalbano, S; Orsoni, N; Pelosi, G; Pioli, M; Rivetti, C; Tarasconi, P1
Cemazar, M; Marković, K; Marković, S; Milačič, R; Ščančar, J; Sersa, G; Unk, M; Uršič, K; Vidmar, J; Žakelj, MN1
Gonçalves, MA; Kuca, K; Mancini, DT; Pereira, BTL; Ramalho, TC1
Cubo, L; Faraco, EJ; Herrero, JM; Matesanz, AI; Quiroga, AG1
Dong, C; Hu, X; Lu, Y; Shi, S; Shi, X; Yao, T1
Dyson, PJ; Murray, BS1
Bian, K; Cong, C; Gao, D; Hao, Z; He, H; He, Y; Li, C; Li, L; Luo, L; Wang, S; Zhang, X; Zhao, Q1
Demontoux, L; Ghiringhelli, F; Pilot, T; Rébé, C1
Bai, F; Han, Q; Luo, Q; Song, G; Wang, Y; Wu, M; Zhang, H1
Alam, M; Choi, SU; Kim, Y; Lee, J; Park, S; Son, YH1
Kepp, O; Kroemer, G1
Dragoe, D; González-Vargas, CR; Lacombe, S; Porcel, E; Remita, H; Salado-Leza, D; Savina, F; Yang, X1
Kahán, Z1
Cui, J; Gao, Z; Hao, J; He, T; Huang, P; Li, X; Lin, J; Zhang, P; Zhang, Y1
Aldrich-Wright, JR; Deo, KM; Khoury, A1
Cao, L; Duan, H; Li, C; Li, Y; Liu, J; Meng, Y; Miao, X; Wang, J; Wang, P; Wang, Q1
Li, Z; Liu, RP; Ma, ZY; Qiao, X; Song, XQ; Wang, SQ; Xie, CZ; Xu, JY; Zhang, R1
Navarro-Ruiz, NE1
Brebi, P; de La Fuente, M; Hermoso, M; Ili, CG; Reyes, ME1
Fan, K; Jiang, B; Jiang, W; Liu, Y; Yan, X; Yang, Y; Zhu, D1
Cao, Q; Ji, LN; Mao, ZW; Pan, ZY; Yang, GG; Zhang, H; Zhou, DJ1
Su, Q; Wang, X; Yang, J; Zhang, M; Zhang, Y; Zhang, Z1
Li, Q; Si, Y; Tian, G; Wang, B; Wu, Z; Xiao, J; Xing, X; Xu, R; Xu, Z; Zhang, G; Zhu, L1
Ge, F; Huang, F; Li, Q; Liu, Y; Mao, Z; Shi, B; Stang, PJ; Wang, S; Yu, G; Zhu, H1
Dai, X; Foda, MF; Han, H; Ma, Z; Zhang, J; Zhang, W; Zhang, Y1
Ahmad, H; Gill, MR; Yusoh, NA1
Ahmedova, A; Mihaylov, L; Mihaylova, R; Mihaylova, V; Momekov, G; Momekova, D; Nihtianova, D; Paunova-Krasteva, T; Stoitsova, S; Stoykova, S; Yoshizawa, M1
Dong, H; Gou, R; Lin, B1
Del Valle, AC; Huang, YF; Yeh, CK1
Chi, Z; Li, J; Liu, S; Ma, Y; Mao, Z; Qian, PC; Wong, WY1
Bauer, A; Bauer, EB; Bernd, MA; Kühn, FE; Oberkofler, J; Reich, RM1
Abbasvandi, F; Abdolahad, M; Aghaee, P; Esmailinejad, MR; Ghafari, H; Hoseinpour, P; Khayamian, MA; Mahdavi, R; Mamdouh, A; Mehrvarz, S; Miripour, ZS; Mousavi-Kiasary, SMS; Namdar, N; Vajhi, AR; Yousefpour, N1
Guo, Q; He, L; Meng, Z; Shao, F; Teulade-Fichou, MP; Wu, X; Yeow, EKL1
Chen, X; Huang, D; Li, J; Ming, J; Shi, Y; Wang, J; Xiang, S; Yang, W; Zheng, N; Zhu, T1
Houthoff, HJ; Merkul, E; Muns, JA; Nijmeijer, B; Reedijk, J; Sijbrandi, NJ; van Dongen, GAMS; van Rheenen, G1
Dai, Z; Meng, Y; Sun, Y; Yu, D; Zhang, D; Zhang, G; Zhang, T; Zheng, X1
Luo, Y; Pei, S; Xiao, Y; Xu, J; Zhu, X1
Cai, X; Cheng, Y; Huang, Q; Li, L; Wang, C; Xiao, J; Yan, Y; Zhang, S1
Bennett, D; Birnbaum, MJ; Breen, DM; Calle, RA; Collins, S; Esquejo, RM; He, T; Joaquim, S; Joyce, A; Kim, H; Lambert, M; Lin, L; Pettersen, B; Qiao, S; Rossulek, M; Weber, G; Wu, Z; Zhang, BB1
Cao, H; Gao, X; Li, J; Liang, M; Ma, Y; Sun, N; Yang, Y1
Byun, E; Campbell, R; Choi, J; Islam, S; Kim, A; Park, M; Shim, H; Song, SH1
Li, X; Liu, D; Lv, S; Miao, Y; Song, F; Zheng, D1
Chen, Q; Dong, J; Han, G; Huang, J; Wang, P; Yang, S; Yu, L; Zhang, Q; Zhang, W1
Gibson, D1
Correia, JDG; Feige, MJ; Gronauer, TF; Jakob, CHG; Kühn, FE; Meighen-Berger, K; Schlagintweit, JF; Sieber, SA; Weigert Muñoz, A; Weiß, V1
Ding, K; Parulekar, WR; Sridhar, SS1
Mitchell, L; New, EJ; Park, SB; Shen, C; Timmins, HC1
Blydt-Hansen, TD; Chui, H; Devarajan, P; Lebel, A; Lim, YJ; Macri, J; McMahon, KR; Urquhart, BL; Wang, S; Zappitelli, M1
Gao, Z; Guo, J; Jian, X; Song, YY; Zhang, X; Zhao, C1
Chen, Y; Li, ZH; Sun, Y; Zhang, XZ1
Hw Chen, H; Lai, YH; Su, WC; Tsai, TL1
Barrabés, S; Carrión, MC; Castañeda, G; Cuevas, JV; Durá, G; Fernández-Aroca, DM; Jalón, FA; Leal, J; Manzano, BR; Martínez, MA; Massaguer, A; Rodríguez, AM; Ruiz-Hidalgo, MJ; Sánchez-Prieto, R; Santos, L1
Allison, WT; Babolmorad, G; Bhavsar, AP; Delyea, C; Domingo, IK; Latif, A; Pollock, NM; Rieger, AM1
Bu, W; Chen, L; Chen, Y; Jiang, X; Jin, D; Li, J; Liu, Y; Wang, K; Wang, Y; Wu, J; Wu, Y; Zhang, H1
Mao, ZW; Shen, J; Zhang, DY; Zhang, H1
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Georgoulias, V; Marselos, M; Mavroudis, D; Nikolaidou, M; Pappas, P1
Beijnen, JH; Bennouna, J; Campone, M; Howell, SB; Nowotnik, DP; Rademaker-Lakhai, JM; Schellens, JH1
Alimonti, A; Bocca, B; Cappelli, C; Caroli, S; Clerico, A; De Ioris, MA; Petrucci, F; Ragni, G; Sordi, A1
Jung, Y; Lippard, SJ1
Ahn, S; Jang, HJ; Kim, HB; Kim, KW; Sim, SB1
Cabral, H; Kataoka, K; Nishiyama, N1
Doroshow, JH; Egorin, MJ; Goetz, A; Graham, MA; Greenslade, D; Grem, JL; Hamilton, A; Ivy, P; Lockwood, G; Mani, S; Mulkerin, DL; Ng, CM; Ramanathan, RK; Remick, SC; Sharma, S; Synold, TW; Takimoto, CH1
Barnés, CM; Barnes, KR; Haskel, A; Lippard, SJ; Mukhopadhyay, S; Short, SM1
Nakajima, TE; Yamada, Y1
Bhattacharya, R; Mukherjee, P1
Drobník, J1
Kidani, Y1
Calvert, AH; Chadwick, R; Harland, SJ; Harrap, KR; Newell, DR; Siddik, ZH1
Kozlova, MD; Lobanova, EA; Serebriakov, NG; Singin, AS1
Aisner, J; Egorin, MJ; Olman, EA; Van Echo, DA; Whitacre, MY1
Gall, HE; Hart, AA; Klein, I; Pinedo, HM; van der Vijgh, WJ; Vermorken, JB1
Campbell, AB; Jacobs, C; Kalman, SM1
Aisner, J; Egorin, MJ; Gerad, H; Van Echo, DA; Whitacre, M1
Kourounakis, P; Pouskouleli, G1
Hurwitz, E; Kashi, R; Wilchek, M1
Crowther, D; Fox, BW; Harrison, R; McAuliffe, CA; Sharma, H; Smith, A; Thatcher, N; Zaki, A1
Kazantzis, G1
Sirover, MA1
Crom, WR; Denison, M; Evans, WE; Green, AA; Hayes, FA; Pratt, CB; Senzer, N; Yee, GC1
Bernard, JL; Bues-Charbit, M; Cano, JP; Catalin, J; Placidi, M; Raybaud, C; Rigault, JP1
Bertram, HP; Kellinghaus, H; Preusser, P; Straub, C; Vetter, H; Zumkley, H1
Borch, R; Hrushesky, WJ; Levi, F1
Dewhirst, MW; Dodge, RK; Lee, J; Page, RL; Riviere, JE; Thrall, DE1
Sgouros, G; Willins, JD1
de Boer-Dennert, M; Ma, J; Planting, AS; Schellens, JH; Stoter, G; van der Burg, ME; van Ingen, HE; Verweij, J1
Gadia, M; Goel, R; Green, RM; Hugenholtz, H; Lamothe, A; Mikhael, NZ; Molepo, JM; Montpetit, VA; Redmond, MD; Stewart, DJ1
Adelstein, SJ; Hamm, RN; Howell, RW; Kassis, AI; Rao, DV; Sastry, KS; Turner, JE; Wright, HA1
Los, G; Muggia, FM1
Ensslin, AS; Fruhmann, G; Pethran, A; Schierl, R1
Blommaert, FA; den Engelse, L; Hart, AA; Kortes, V; Michael, C; Muggia, FM; Schornagel, JH; Terheggen, PM1
Catane, R; Gorodetsky, R; Kaufman, B; Loewenthal, E; Mou, X; Vexler, A1
Beaney, RP; Braithwaite, RA; Buxton, EJ; Chettle, DR; Scott, MC; Somervaille, LJ; Todd, AC1
Adelstein, D; Bauer, L; Budd, GT; Bukowski, RM; Ganapathi, R; Gibson, V; McLain, D; Murthy, S; Sergi, J; Weick, J1
Kakehi, M; Kubota, N1
Rau, T; van Eldik, R1
Christian, MC; Davis, P; Figg, WD; Jacobs, J; Kohn, E; Link, CJ; Lush, R; Reed, E; Rothenberg, ML; Ryan, N; Sarosy, G; Weiss, RB1
Bagarry-Liegey, D; Catalin, J; Duffaud, F; Durand, A; Favre, R; Guillet, P; Lacarelle, B; Monjanel, S; Nicoara, A1
Khuhawar, MY; Lanjwani, SN; Memon, SA1
Dulberg, CS; Goel, R; Mikhael, NZ; Montpetit, VA; Redmond, MD; Stewart, DJ1
Boddy, AV; English, MW; Newell, DR; Pearson, AD; Peng, B; Price, L; Tilby, MJ; Wyllie, R1
Fichtinger-Schepman, AM; Gall, HE; Korst, AE; van der Sterre, ML; van der Vijgh, WJ; Vermorken, JB1
Apostoli, P; Bonetti, A; Cetto, GL; Colombatti, M; Franceschi, T; Leone, R; Pavanel, F; Sperotto, L; Zaninelli, M1
Areberg, J; Björkman, S; Einarsson, L; Frankenberg, B; Lundqvist, H; Mattsson, S; Norrgren, K; Scheike, O; Wallin, R1
Boven, E; Gall, HE; van der Vijgh, WJ; Vermorken, JB; Welink, J1
Brès, J; Constans, B; Cupissol, D; Gau, F; Gory-Delabaere, G; Nouguier-Soulé, J1
al-Hussany, A; Ali, PA; el-Sharkawi, AM; Hancock, DA; Kadhim, R1
Bartholdy, NJ; Guimaraens, L; Houdart, E; Kühne, D; Levrier, O; Murph, KJ; Rüfenacht, DA; Solymosi, L; Sugiu, K; Szopinski, KT1
Fontes, E; Nilsson, E1
Aiba, K; Akaza, H; Hoctin-Boes, G; Isonishi, S; Kawai, K; Konishi, T; Mikami, O; Miki, T; Noguchi, S; Ohashi, Y; Saeki, T; Saijo, N; Smith, M; Sone, S; Stribling, D; Tsukagoshi, S; Tsuruo, T1
Atagi, S; Hanada, K; Kawahara, M; Nishijima, K; Ogata, H1
Petsko, GA1
Kim, YS; Sohn, YS; Song, R1
Beijnen, JH; Groenewegen, G; Huisman, A; Maliepaard, M; Meerum Terwogt, JM; Pluim, D; Schellens, JM; Schot, M; ten Bokkel Huinink, WW; Tibben, MM; Voest, EE; Welbank, H1
Degos, L; Demetri, GD; Dicato, M; Glaspy, J1
Balcerzak, S; Bender, J; Brooks, R; Chan, KK; D'Ambrosio, S; Gibson-D'Ambrosio, R; Grever, M; Kraut, E; Liu, J; Stanley, H1
Carter, SK; Muggia, FM; Rozencweig, M; Slavik, M1
Kirschner, S; Kravitz, SH1
Harrap, KR1
Whitehouse, MW1
Copeland, ES; Demple, B; Kulesz-Martin, M; Wetterhahn, KE1
van der Vijgh, WJ1
Reed, E1
Brann, TW; Frei, E; Herman, TS; Holden, SA; Khandekar, V; Korbut, TT; Rosbe, KW; Sotomayor, EA; Teicher, BA1
de Vries, EG; Meijer, S; Mulder, NH; Postmus, PE; Sleijfer, DT; Smit, EF; Terheggen, PM; Uges, DR; Willemse, PH1
Evetts, I; Mason, R; Milton, D1
Gill, I; Grunberg, S; Muggia, FM; Parker, RJ; Reed, E; Tarone, R; Vionnet, JA1
Adam, R; Brienza, S; Caussanel, JP; Hecquet, B; Itzhaki, M; Lévi, F; Mathé, G; Milano, G; Misset, JL1
Perevodchikova, NI1
Gilman, JP; McLean, JR; Swierenga, SH1
Lahmann, E; Thron, HL1
Amer, M; el-Yazigi, A; Martin, CR1
Gorbunova, VA1
DeGregorio, MW; Denham, A; Gandara, DR; Perez, EA; Wiebe, VJ1
Hemminki, K; Hietanen, P; Leppälä, S; Mustonen, R; Takala, M1
Ahmadi, J; Bertram, J; Chen, DC; Dahalan, R; Kawada, TK; Kempf, RA; Muggia, FM; Parti, R; Russell, C; Shani, J1
Favre, R; Hecquet, B1
Jonson, R; Mattsson, S; Unsgaard, B1
Howard, K; Kacew, S; Maroun, JA; Mikhael, NZ; Montpetit, V; Nair, RC; Nanji, A; Stewart, DJ1
Elferink, F; Gall, HE; Klein, I; McVie, JG; Pinedo, HM; Simonetti, G; ten Bokkel Huinink, WW; van der Vijgh, WJ; Vermorken, JB1
Hoth, DF; Leyland-Jones, B; O'Dwyer, PJ; Wittes, RE1
Apostoli, P; Benoni, G; Bonetti, A; Fracasso, ME; Griso, C; Leone, R1
Gill, PG; Reece, PA; Russell, J; Stafford, I2
Al-Saleh, I; el-Yazigi, A1
Nias, AH1
Coughlin, CT; Douple, EB; O'Hara, JA; Richmond, RC1
Dubbelman, R; Franklin, H; Klein, I; McVie, JG; ten Bokkel Huinink, W; van der Vijgh, W1
Gall, HE; Hart, GA; Klein, I; Pinedo, HM; van der Vijgh, WJ; van Groeningen, CJ; Vermorken, JB1
Mansour, EG; Pories, WJ; Strain, WH1
Jones, TD1
Perlia, CP; Rossof, AH; Slayton, RE1
Dohnalová, J; Dostálová, O; Drobník, J; Fiserová, J; Holík, F1
Beran, M; Motycka, K1
Nagase, T; Ogiso, A; Suzuki, S; Tanaka, M; Yoshioka, T1
Iakhontov, NE; Kopytkin, IuV1

Reviews

101 review(s) available for platinum and Neoplasms

ArticleYear
A highly annotated database of genes associated with platinum resistance in cancer.
    Oncogene, 2021, Volume: 40, Issue:46

    Topics: Data Curation; Databases, Genetic; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Neoplasms; Platinum; Tumor Microenvironment

2021
Advances in Delivery of Chemotherapeutic Agents for Cancer Treatment.
    AAPS PharmSciTech, 2021, Dec-14, Volume: 23, Issue:1

    Topics: Antineoplastic Agents; Drug Carriers; Drug Delivery Systems; Gold; Humans; Metal Nanoparticles; Nanoparticles; Nanotubes, Carbon; Neoplasms; Platinum

2021
Advances in FePt-involved nano-system design and application for bioeffect and biosafety.
    Journal of materials chemistry. B, 2022, 01-19, Volume: 10, Issue:3

    Topics: Animals; Antineoplastic Agents; Catalysis; Cell Line, Tumor; Drug Carriers; Humans; Hydrogen Peroxide; Iron; Metal Nanoparticles; Nanocomposites; Neoplasms; Platinum; Precision Medicine

2022
Platinum-based drugs for cancer therapy and anti-tumor strategies.
    Theranostics, 2022, Volume: 12, Issue:5

    Topics: Antineoplastic Agents; Carboplatin; Cisplatin; Humans; Neoplasms; Oxaliplatin; Platinum

2022
Challenges and opportunities in the development of metal-based anticancer theranostic agents.
    Bioscience reports, 2022, 05-27, Volume: 42, Issue:5

    Topics: Antineoplastic Agents; Humans; Neoplasms; Platinum; Precision Medicine; Theranostic Nanomedicine

2022
Recent Advances and Therapeutic Journey of Schiff Base Complexes with Selected Metals (Pt, Pd, Ag, Au) as Potent Anticancer Agents: A Review.
    Anti-cancer agents in medicinal chemistry, 2022, Volume: 22, Issue:18

    Topics: Antineoplastic Agents; Cisplatin; Coordination Complexes; Gold; Humans; Neoplasms; Palladium; Platinum; Schiff Bases; Silver

2022
Global burden of ototoxic hearing loss associated with platinum-based cancer treatment: A systematic review and meta-analysis.
    Cancer epidemiology, 2022, Volume: 79

    Topics: Antineoplastic Agents; Carboplatin; Cisplatin; Hearing Loss; Humans; Neoplasms; Ototoxicity; Platinum

2022
Platinum nanoplatforms: classic catalysts claiming a prominent role in cancer therapy.
    Chemical Society reviews, 2022, Aug-30, Volume: 51, Issue:17

    Topics: Catalysis; Humans; Metal Nanoparticles; Neoplasms; Platinum; Tissue Distribution; Tumor Microenvironment

2022
Elesclomol: a copper ionophore targeting mitochondrial metabolism for cancer therapy.
    Journal of experimental & clinical cancer research : CR, 2022, Sep-12, Volume: 41, Issue:1

    Topics: Copper; Humans; Hydrazines; Ionophores; Neoplasms; Platinum; Proteasome Inhibitors

2022
The role of Platinum(IV)-based antitumor drugs and the anticancer immune response in medicinal inorganic chemistry. A systematic review from 2017 to 2022.
    European journal of medicinal chemistry, 2022, Dec-05, Volume: 243

    Topics: Antineoplastic Agents; Chemistry, Inorganic; Humans; Immunity; Ligands; Neoplasms; Platinum; Prodrugs

2022
Recent advances in luminescent metallacycles/metallacages for biomedical imaging and cancer therapy.
    Dalton transactions (Cambridge, England : 2003), 2022, Nov-08, Volume: 51, Issue:43

    Topics: Antineoplastic Agents; Contrast Media; Fluorescent Dyes; Humans; Neoplasms; Platinum

2022
Metallo-Drugs in Cancer Therapy: Past, Present and Future.
    Molecules (Basel, Switzerland), 2022, Oct-01, Volume: 27, Issue:19

    Topics: Antineoplastic Agents; Coordination Complexes; Copper; Humans; Neoplasms; Platinum; Ruthenium

2022
Emerging platinum(0) nanotherapeutics for efficient cancer therapy.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 352

    Topics: Cell Line, Tumor; Neoplasms; Photochemotherapy; Platinum

2022
Platinum glycoconjugates: "Sweet bullets" for targeted cancer therapy?
    Current opinion in chemical biology, 2023, Volume: 72

    Topics: Antineoplastic Agents; Drug Delivery Systems; Glycoconjugates; Humans; Neoplasms; Platinum

2023
Experimental drugs for fallopian cancer: promising agents in the clinical trials and key stumbling blocks for researchers.
    Expert opinion on investigational drugs, 2022, Volume: 31, Issue:12

    Topics: Female; Humans; Immunotherapy; Mutation; Neoplasms; Platinum; Poly(ADP-ribose) Polymerase Inhibitors

2022
The long-term impacts of hearing loss, tinnitus and poor balance on the quality of life of people living with and beyond cancer after platinum-based chemotherapy: a literature review.
    Journal of cancer survivorship : research and practice, 2023, Volume: 17, Issue:1

    Topics: Adult; Antineoplastic Agents; Cancer Survivors; Carboplatin; Child; Cisplatin; Hearing Loss; Humans; Neoplasms; Ototoxicity; Platinum; Quality of Life; Tinnitus

2023
Will the Interactions of Some Platinum (II)-Based Drugs with B-Vitamins Reduce Their Therapeutic Effect in Cancer Patients? Comparison of Chemotherapeutic Agents such as Cisplatin, Carboplatin and Oxaliplatin-A Review.
    International journal of molecular sciences, 2023, Jan-12, Volume: 24, Issue:2

    Topics: Antineoplastic Agents; Carboplatin; Cisplatin; Humans; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Platinum; Vitamin B Complex

2023
Insight into autophagy in platinum resistance of cancer.
    International journal of clinical oncology, 2023, Volume: 28, Issue:3

    Topics: Antineoplastic Agents; Autophagy; Drug Resistance, Neoplasm; Humans; Neoplasms; Platinum

2023
The safety of combining immune checkpoint inhibitors and platinum-based chemotherapy for the treatment of solid tumors: A systematic review and network meta-analysis.
    Frontiers in immunology, 2023, Volume: 14

    Topics: Antineoplastic Agents, Immunological; Humans; Immune Checkpoint Inhibitors; Ipilimumab; Neoplasms; Network Meta-Analysis; Platinum; Randomized Controlled Trials as Topic

2023
Platinum Drug-Incorporating Polymeric Nanosystems for Precise Cancer Therapy.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:21

    Topics: Antineoplastic Agents; Drug Delivery Systems; Humans; Neoplasms; Platinum; Polymers; Prodrugs

2023
Supramolecular platinum complexes for cancer therapy.
    Current opinion in chemical biology, 2023, Volume: 73

    Topics: Antineoplastic Agents; Drug Delivery Systems; Humans; Neoplasms; Platinum; Prodrugs

2023
Addressing the gaps in homeostatic mechanisms of copper and copper dithiocarbamate complexes in cancer therapy: a shift from classical platinum-drug mechanisms.
    Dalton transactions (Cambridge, England : 2003), 2023, May-09, Volume: 52, Issue:18

    Topics: Animals; Antineoplastic Agents; Cisplatin; Coordination Complexes; Copper; Humans; Mammals; Neoplasms; Platinum

2023
Recent Advances of Platinum-Based Anticancer Complexes in Combinational Multimodal Therapy.
    Advanced healthcare materials, 2023, Volume: 12, Issue:22

    Topics: Anti-Infective Agents; Antineoplastic Agents; Combined Modality Therapy; Humans; Neoplasms; Penicillins; Platinum

2023
The Challenging Treatment of Cisplatin-Resistant Tumors: State of the Art and Future Perspectives.
    Molecules (Basel, Switzerland), 2023, Apr-12, Volume: 28, Issue:8

    Topics: Antineoplastic Agents; Cisplatin; Humans; Ligands; Neoplasms; Platinum

2023
Biomedical,clinical and environmental applications of platinum-based nanohybrids: An updated review.
    Environmental research, 2023, 08-15, Volume: 231, Issue:Pt 2

    Topics: Anti-Infective Agents; Antineoplastic Agents; Humans; Metal Nanoparticles; Neoplasms; Oxides; Platinum

2023
Polysaccharide‑platinum complexes for cancer theranostics.
    Carbohydrate polymers, 2023, Sep-01, Volume: 315

    Topics: Antineoplastic Agents; Humans; Neoplasms; Platinum; Precision Medicine

2023
The Role of mTORC1 Pathway and Autophagy in Resistance to Platinum-Based Chemotherapeutics.
    International journal of molecular sciences, 2023, Jun-26, Volume: 24, Issue:13

    Topics: Antineoplastic Agents; Autophagy; Cisplatin; Drug Resistance, Neoplasm; Humans; Mechanistic Target of Rapamycin Complex 1; Neoplasms; Platinum

2023
[Mechanisms of platinum-induced peripheral neuropathy in cancer patients].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2023, Volume: 123, Issue:7

    Topics: Antineoplastic Agents; Humans; Neoplasms; Peripheral Nervous System Diseases; Platinum; Polyneuropathies; Quality of Life

2023
Platinum based theranostics nanoplatforms for antitumor applications.
    Journal of materials chemistry. B, 2023, 09-13, Volume: 11, Issue:35

    Topics: Antineoplastic Agents; Humans; Neoplasms; Photochemotherapy; Platinum; Precision Medicine

2023
Emerging platinum(IV) prodrug nanotherapeutics: A new epoch for platinum-based cancer therapy.
    Journal of controlled release : official journal of the Controlled Release Society, 2023, Volume: 361

    Topics: Combined Modality Therapy; Drug Delivery Systems; Humans; Medical Oncology; Neoplasms; Platinum; Prodrugs

2023
Recent progress in the development of organometallics for the treatment of cancer.
    Current opinion in chemical biology, 2020, Volume: 56

    Topics: Animals; Antineoplastic Agents; Chromatin; Combined Modality Therapy; Dose-Response Relationship, Drug; Gold; Humans; Models, Molecular; Neoplasms; Organometallic Compounds; Photochemotherapy; Platinum; Ruthenium; Silver

2020
Platinum Derivatives Effects on Anticancer Immune Response.
    Biomolecules, 2019, 12-20, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Agents; Humans; Immune System; Immunologic Factors; Neoplasms; Platinum

2019
[Medical treatment options in BRCA-associated cancers].
    Magyar onkologia, 2020, Mar-17, Volume: 64, Issue:1

    Topics: Genes, BRCA1; Genes, BRCA2; Humans; Mutation; Neoplasms; Platinum; Poly(ADP-ribose) Polymerase Inhibitors

2020
Recent advances in platinum-based chemotherapeutics that exhibit inhibitory and targeted mechanisms of action.
    Journal of inorganic biochemistry, 2020, Volume: 207

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cisplatin; Coordination Complexes; Humans; Ligands; Mitochondria; Neoplasms; Organoplatinum Compounds; Platinum; Platinum Compounds; Prostaglandin-Endoperoxide Synthases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase

2020
Prevention of Platinum-Induced Hearing Loss in Children with Cancer.
    The American journal of nursing, 2020, Volume: 120, Issue:6

    Topics: Amifostine; Humans; Neoplasms; Ototoxicity; Platinum; Practice Guidelines as Topic; Thiosulfates

2020
Role of CC Chemokines Subfamily in the Platinum Drugs Resistance Promotion in Cancer.
    Frontiers in immunology, 2020, Volume: 11

    Topics: Cell Proliferation; Chemokines, CC; Drug Resistance, Neoplasm; Humans; Inflammation; Neoplasms; Platinum; Signal Transduction; Tumor Microenvironment

2020
Combining PARP Inhibition with Platinum, Ruthenium or Gold Complexes for Cancer Therapy.
    ChemMedChem, 2020, 11-18, Volume: 15, Issue:22

    Topics: Antineoplastic Agents; Coordination Complexes; Gold; Humans; Neoplasms; Platinum; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Ruthenium

2020
Application and reflection of genomic scar assays in evaluating the efficacy of platinum salts and PARP inhibitors in cancer therapy.
    Life sciences, 2020, Nov-15, Volume: 261

    Topics: Animals; Antineoplastic Agents; Epigenesis, Genetic; Genomics; Humans; Mutation; Neoplasms; Platinum; Poly(ADP-ribose) Polymerase Inhibitors; Recombinational DNA Repair

2020
Platinum(IV) anticancer agents; are we en route to the holy grail or to a dead end?
    Journal of inorganic biochemistry, 2021, Volume: 217

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Coordination Complexes; DNA Repair; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Histone Deacetylase Inhibitors; Humans; Neoplasms; Platinum; Prodrugs

2021
Platinum-based chemotherapy
    Biomaterials science, 2021, Sep-14, Volume: 9, Issue:18

    Topics: Antineoplastic Agents; Drug Carriers; Drug Delivery Systems; Humans; Micelles; Neoplasms; Platinum

2021
Hypersensitivity Reactions to Platinum Agents and Taxanes.
    Clinical reviews in allergy & immunology, 2022, Volume: 62, Issue:3

    Topics: Antineoplastic Agents; Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans; Neoplasms; Platinum; Skin Tests; Taxoids

2022
Advancements in the Use of Platinum Complexes as Anticancer Agents.
    Anti-cancer agents in medicinal chemistry, 2022, Volume: 22, Issue:5

    Topics: Antineoplastic Agents; Carboplatin; Cisplatin; Humans; Neoplasms; Oxaliplatin; Platinum

2022
Platinum, palladium, gold and ruthenium complexes as anticancer agents: Current clinical uses, cytotoxicity studies and future perspectives.
    European journal of medicinal chemistry, 2017, Dec-15, Volume: 142

    Topics: Animals; Antineoplastic Agents; Coordination Complexes; Drug Discovery; Gold; Humans; Neoplasms; Palladium; Platinum; Ruthenium

2017
Electrolyte disorders with platinum-based chemotherapy: mechanisms, manifestations and management.
    Cancer chemotherapy and pharmacology, 2017, Volume: 80, Issue:5

    Topics: Humans; Neoplasms; Platinum; Water-Electrolyte Imbalance

2017
Chemotherapeutic Drugs and Plasma Proteins: Exploring New Dimensions.
    Current protein & peptide science, 2018, Volume: 19, Issue:10

    Topics: Antineoplastic Agents; Blood Proteins; Cell Survival; Cisplatin; Coordination Complexes; Fluorouracil; Humans; Neoplasms; Platinum; Ruthenium

2018
Trabectedin mechanism of action and platinum resistance: molecular rationale.
    Future oncology (London, England), 2017, Volume: 13, Issue:23s

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Dioxoles; DNA; Drug Resistance, Neoplasm; Genes, BRCA1; Genes, BRCA2; Humans; Mutation; Neoplasms; Platinum; Prognosis; Tetrahydroisoquinolines; Trabectedin; Treatment Outcome

2017
Copper efflux transporters ATP7A and ATP7B: Novel biomarkers for platinum drug resistance and targets for therapy.
    IUBMB life, 2018, Volume: 70, Issue:3

    Topics: Biomarkers, Tumor; Copper-Transporting ATPases; Drug Resistance, Neoplasm; Humans; Neoplasms; Platinum

2018
Under-Reported Aspects of Platinum Drug Pharmacology.
    Molecules (Basel, Switzerland), 2017, Feb-28, Volume: 22, Issue:3

    Topics: Animals; Antineoplastic Agents; DNA Damage; Gene Expression Regulation; Humans; Hydrolysis; Immune System; Neoplasms; Platinum; Signal Transduction; Structure-Activity Relationship; Tissue Distribution

2017
Impact of aging on the risk of platinum-related renal toxicity: A systematic review and meta-analysis.
    Cancer treatment reviews, 2018, Volume: 69

    Topics: Aged; Antineoplastic Agents; Drug-Related Side Effects and Adverse Reactions; Humans; Kidney Diseases; Neoplasms; Platinum; Prognosis

2018
Platinum-induced muscle wasting in cancer chemotherapy: Mechanisms and potential targets for therapeutic intervention.
    Life sciences, 2018, Sep-01, Volume: 208

    Topics: Animals; Antineoplastic Agents; Cachexia; Humans; Muscle, Skeletal; Neoplasms; Platinum; Quality of Life

2018
Stimuli-Responsive Therapeutic Metallodrugs.
    Chemical reviews, 2019, 01-23, Volume: 119, Issue:2

    Topics: Antineoplastic Agents; Coordination Complexes; Humans; Hydrogen-Ion Concentration; Light; Neoplasms; Oxidation-Reduction; Platinum; Ruthenium; Temperature

2019
Use of Anticancer Platinum Compounds in Combination Therapies and Challenges in Drug Delivery.
    Current medicinal chemistry, 2020, Volume: 27, Issue:18

    Topics: Antineoplastic Agents; Drug Delivery Systems; Humans; Neoplasms; Platinum; Platinum Compounds

2020
Toward Multi-Targeted Platinum and Ruthenium Drugs-A New Paradigm in Cancer Drug Treatment Regimens?
    Chemical reviews, 2019, 01-23, Volume: 119, Issue:2

    Topics: ATP-Binding Cassette Transporters; Coordination Complexes; DNA Damage; Enzymes; Humans; Neoplasms; Platinum; Prodrugs; Ruthenium

2019
Mechanisms of Chemotherapy-Induced Peripheral Neuropathy.
    International journal of molecular sciences, 2019, Mar-22, Volume: 20, Issue:6

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; DNA Damage; Humans; Neoplasms; Oxidative Stress; Peripheral Nervous System Diseases; Platinum; Protein Kinase Inhibitors; Reactive Oxygen Species; Signal Transduction

2019
Cisplatin: The first metal based anticancer drug.
    Bioorganic chemistry, 2019, Volume: 88

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Coordination Complexes; DNA; Drug Resistance, Neoplasm; Humans; Metal Nanoparticles; Neoplasms; Platinum

2019
Recent advances in ruthenium and platinum based supramolecular coordination complexes for antitumor therapy.
    Colloids and surfaces. B, Biointerfaces, 2019, Oct-01, Volume: 182

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Coordination Complexes; Humans; Mice; Molecular Structure; Neoplasms; Platinum; Ruthenium; Xenograft Model Antitumor Assays

2019
Metals and metal derivatives in medicine.
    Mini reviews in medicinal chemistry, 2013, Volume: 13, Issue:2

    Topics: Animals; Antineoplastic Agents; Coordination Complexes; DNA; Humans; Metals; Models, Molecular; Neoplasms; Platinum; Proteins

2013
Understanding platinum-induced ototoxicity.
    Trends in pharmacological sciences, 2013, Volume: 34, Issue:8

    Topics: Animals; Antineoplastic Agents; Carboplatin; Child; Cisplatin; Ear Diseases; Humans; Neoplasms; Platinum; Quality of Life; Risk Factors

2013
Effects of light-activated diazido-PtIV complexes on cancer cells in vitro.
    Philosophical transactions. Series A, Mathematical, physical, and engineering sciences, 2013, Jul-28, Volume: 371, Issue:1995

    Topics: Animals; Antineoplastic Agents; Azides; Humans; Light; Neoplasms; Photochemotherapy; Photosensitizing Agents; Platinum

2013
Light-induced catalytic and cytotoxic properties of phosphorescent transition metal compounds with a d8 electronic configuration.
    Philosophical transactions. Series A, Mathematical, physical, and engineering sciences, 2013, Jul-28, Volume: 371, Issue:1995

    Topics: Catalysis; DNA Damage; Gold; Light; Neoplasms; Photochemotherapy; Photosensitizing Agents; Platinum; Transition Elements

2013
Metal-N-heterocyclic carbene complexes as anti-tumor agents.
    Current medicinal chemistry, 2014, Volume: 21, Issue:10

    Topics: Antineoplastic Agents; Auranofin; Cell Line, Tumor; Cisplatin; Coordination Complexes; Copper; Gold; Heterocyclic Compounds; Humans; Methane; Neoplasms; Palladium; Platinum; Silver; Structure-Activity Relationship

2014
[Nanoparticles and radiation therapy].
    Bulletin du cancer, 2015, Volume: 102, Issue:1

    Topics: Gadolinium; Gold; Humans; Metal Nanoparticles; Neoplasms; Platinum; Radiation-Sensitizing Agents; Silver

2015
Third row transition metals for the treatment of cancer.
    Philosophical transactions. Series A, Mathematical, physical, and engineering sciences, 2015, Mar-13, Volume: 373, Issue:2037

    Topics: Antineoplastic Agents; Cross-Linking Reagents; DNA; DNA Repair; Drug Design; Humans; Models, Chemical; Neoplasms; Platinum; Transition Elements

2015
Speciation of precious metal anti-cancer complexes by NMR spectroscopy.
    Drug discovery today. Technologies, 2015, Volume: 16

    Topics: Animals; Antineoplastic Agents; Coordination Complexes; Gold; Humans; Magnetic Resonance Spectroscopy; Metals, Heavy; Neoplasms; Platinum; Rhodium

2015
Exploiting developments in nanotechnology for the preferential delivery of platinum-based anti-cancer agents to tumours: targeting some of the hallmarks of cancer.
    Metallomics : integrated biometal science, 2016, Volume: 8, Issue:1

    Topics: Antineoplastic Agents; Drug Delivery Systems; Humans; Nanotechnology; Neoplasms; Platinum

2016
Novel strategies for molecular targeting to cancer.
    Clinical and experimental pharmacology & physiology, 2016, Volume: 43, Issue:3

    Topics: Animals; Drug Resistance, Neoplasm; Humans; Molecular Targeted Therapy; Neoplasm Metastasis; Neoplasms; Platinum

2016
Multifunctional platinum-based nanoparticles for biomedical applications.
    Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology, 2017, Volume: 9, Issue:2

    Topics: Animals; Antineoplastic Agents; Drug Delivery Systems; Humans; Metal Nanoparticles; Mice; Neoplasms; Platinum; Theranostic Nanomedicine

2017
The role of annexin A4 in cancer.
    Frontiers in bioscience (Landmark edition), 2016, 06-01, Volume: 21, Issue:5

    Topics: Annexin A4; Calcium; Carboplatin; Chlorides; Copper-Transporting ATPases; Drug Resistance, Neoplasm; Female; Gene Knockdown Techniques; Humans; Male; Neoplasms; NF-kappa B; Platinum; Up-Regulation

2016
Current scenario of biomedical aspect of metal-based nanoparticles on gel dosimetry.
    Applied microbiology and biotechnology, 2016, Volume: 100, Issue:11

    Topics: Animals; Bismuth; Cell Line, Tumor; Disease Models, Animal; Gadolinium; Gels; Gold; Hafnium; Humans; Iodine; Iron; Metal Nanoparticles; Nanotechnology; Neoplasms; Oxides; Platinum; Radiometry; Radiotherapy Dosage; Silver

2016
A meta-analysis identifies ERCC1 gene polymorphism as a predictor of better patient response to treatment with radiochemotherapy.
    Cancer chemotherapy and pharmacology, 2016, Volume: 77, Issue:6

    Topics: Antineoplastic Agents; Chemoradiotherapy; DNA-Binding Proteins; Endonucleases; Genetic Markers; Humans; Neoplasms; Odds Ratio; Platinum; Polymorphism, Single Nucleotide; Predictive Value of Tests; Treatment Outcome; White People

2016
Pathophysiology of cardiotoxicity induced by nonanthracycline chemotherapy.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2016, Volume: 17 Suppl 1 Special issue on Cardiotoxicity fr

    Topics: Anthracyclines; Anti-Bacterial Agents; Antineoplastic Agents, Alkylating; Cardiotoxicity; Fluorouracil; Heart Failure; Humans; Neoplasms; Oxidative Stress; Platinum; Stroke Volume; Taxoids; Ventricular Dysfunction, Left

2016
Combination Platinum-based and DNA Damage Response-targeting Cancer Therapy: Evolution and Future Directions.
    Current medicinal chemistry, 2017, Volume: 24, Issue:15

    Topics: Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Coordination Complexes; DNA Adducts; DNA Damage; DNA Repair; Humans; Neoplasms; Nuclear Proteins; Platinum; Poly(ADP-ribose) Polymerase Inhibitors; Protein-Tyrosine Kinases

2017
Neurotoxicity Associated with Platinum-Based Anti-Cancer Agents: What are the Implications of Copper Transporters?
    Current medicinal chemistry, 2017, Volume: 24, Issue:15

    Topics: Adenosine Triphosphatases; Antineoplastic Agents; Carboplatin; Cation Transport Proteins; Cisplatin; DNA Adducts; Humans; Neoplasms; Neurons; Organoplatinum Compounds; Oxaliplatin; Platinum

2017
Platinum drug distribution in cancer cells and tumors.
    Chemical reviews, 2009, Volume: 109, Issue:10

    Topics: Animals; Antineoplastic Agents; Humans; Models, Biological; Neoplasms; Platinum

2009
Platinum speciation used for elucidating activation or inhibition of Pt-containing anti-cancer drugs.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2010, Volume: 24, Issue:2

    Topics: Antineoplastic Agents; Humans; Ligands; Molecular Structure; Neoplasms; Nucleotides; Platinum; Proteins

2010
Inorganic nanoparticles in cancer therapy.
    Pharmaceutical research, 2011, Volume: 28, Issue:2

    Topics: Animals; Drug Carriers; Drug Delivery Systems; Gold; Humans; Metal Nanoparticles; Mice; Nanomedicine; Neoplasms; Pharmaceutical Preparations; Platinum; Silver

2011
Tuning heavy metal compounds for anti-tumor activity: is diversity the key to ruthenium's success?
    Future medicinal chemistry, 2009, Volume: 1, Issue:3

    Topics: Antineoplastic Agents; Coordination Complexes; Humans; Neoplasms; Platinum; Ruthenium

2009
Mechanism of tumor resistance to cisplatin mediated by the copper transporter ATP7B.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2011, Volume: 89, Issue:2

    Topics: Adenosine Triphosphatases; Antineoplastic Agents; Binding Sites; Biological Transport; Cation Transport Proteins; Cisplatin; Copper; Copper-Transporting ATPases; Drug Resistance, Neoplasm; Humans; Models, Molecular; Molecular Structure; Neoplasms; Platinum; Protein Binding

2011
Platinum formulations as anticancer drugs clinical and pre-clinical studies.
    Current topics in medicinal chemistry, 2011, Volume: 11, Issue:21

    Topics: Antibodies; Antineoplastic Agents; Clinical Trials as Topic; Drug Delivery Systems; Drug Evaluation, Preclinical; Humans; Iron-Binding Proteins; Molecular Targeted Therapy; Nanoparticles; Neoplasms; Organoplatinum Compounds; Oxidation-Reduction; Platinum; Polymers

2011
Anticancer platinum (IV) prodrugs with novel modes of activity.
    Current topics in medicinal chemistry, 2011, Volume: 11, Issue:21

    Topics: Antineoplastic Agents; Drug Delivery Systems; Humans; Molecular Targeted Therapy; Nanotubes, Carbon; Neoplasms; Organoplatinum Compounds; Phototherapy; Platinum; Prodrugs

2011
Non-classical structures among current platinum complexes with potential as antitumor drugs.
    Current topics in medicinal chemistry, 2011, Volume: 11, Issue:21

    Topics: Antineoplastic Agents; Blood Proteins; Cell Cycle Checkpoints; Cell Line, Tumor; DNA; Drug Design; Humans; Neoplasms; Organoplatinum Compounds; Platinum; Protein Binding; Thiosemicarbazones

2011
Membrane transporters as determinants of the pharmacology of platinum anticancer drugs.
    Current cancer drug targets, 2012, Volume: 12, Issue:8

    Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents; ATP-Binding Cassette Transporters; Cation Transport Proteins; Cisplatin; Copper-Transporting ATPases; Humans; Membrane Transport Proteins; Neoplasms; Platinum; Platinum Compounds; SLC31 Proteins; Treatment Outcome

2012
Noble metal-dithiocarbamates precious allies in the fight against cancer.
    Mini reviews in medicinal chemistry, 2012, Volume: 12, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; Coordination Complexes; Copper; Gold; Humans; Neoplasms; Palladium; Platinum; Ruthenium; Thiocarbamates

2012
Combination therapy: histone deacetylase inhibitors and platinum-based chemotherapeutics for cancer.
    Cancer letters, 2013, Feb-01, Volume: 329, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; DNA; Drug Design; Histone Deacetylase Inhibitors; Humans; Neoplasms; Platinum; Platinum Compounds

2013
Platinum group antitumor chemistry: design and development of new anticancer drugs complementary to cisplatin.
    Current medicinal chemistry, 2006, Volume: 13, Issue:11

    Topics: Animals; Antineoplastic Agents; Cisplatin; Drug Design; Humans; Neoplasms; Nickel; Palladium; Platinum

2006
Direct cellular responses to platinum-induced DNA damage.
    Chemical reviews, 2007, Volume: 107, Issue:5

    Topics: Animals; Antineoplastic Agents; DNA; DNA Damage; DNA Repair; Humans; Neoplasms; Platinum

2007
Biological properties of "naked" metal nanoparticles.
    Advanced drug delivery reviews, 2008, Aug-17, Volume: 60, Issue:11

    Topics: Animals; Drug Delivery Systems; Gold; Humans; Metal Nanoparticles; Neoplasms; Neovascularization, Pathologic; Platinum; Silver

2008
Antitumor activity of platinum complexes.
    Cancer chemotherapy and pharmacology, 1983, Volume: 10, Issue:3

    Topics: Animals; Antineoplastic Agents; Cisplatin; DNA; DNA Replication; Humans; Kinetics; Neoplasms; Platinum; Structure-Activity Relationship

1983
[Coordinated platinum compounds in experimental and clinical oncology].
    Meditsinskaia radiologiia, 1984, Volume: 29, Issue:6

    Topics: Animals; Chemical Phenomena; Chemistry; Cisplatin; Drug Evaluation; Humans; Kinetics; Leukemia, Experimental; Male; Mice; Neoplasms; Neoplasms, Experimental; Platinum; Testicular Neoplasms

1984
Platinum compounds in cancer chemotherapy.
    Biochemistry and experimental biology, 1980, Volume: 16, Issue:2

    Topics: Animals; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Cytoskeleton; DNA; DNA Replication; Doxorubicin; Drug Therapy, Combination; Humans; Lethal Dose 50; Models, Molecular; Neoplasms; Platinum; Sarcoma, Experimental; Tissue Distribution

1980
Role of cobalt, iron, lead, manganese, mercury, platinum, selenium, and titanium in carcinogenesis.
    Environmental health perspectives, 1981, Volume: 40

    Topics: Animals; Cobalt; Environmental Exposure; Humans; Iron; Lead; Manganese; Mercury; Metals; Mutagenicity Tests; Neoplasms; Platinum; Selenium; Titanium

1981
Effects of metals in in vitro bioassays.
    Environmental health perspectives, 1981, Volume: 40

    Topics: Animals; Arsenic; Biological Assay; Cell Transformation, Neoplastic; Cell Transformation, Viral; Chromium; Chromosome Aberrations; Cricetinae; Humans; Mesocricetus; Metals; Mutagenicity Tests; Neoplasms; Platinum; Selenium

1981
Platinum resistance. Experimental and clinical status.
    Hematology/oncology clinics of North America, 1994, Volume: 8, Issue:2

    Topics: Biological Transport; Clinical Trials as Topic; DNA Repair; Drug Resistance; Humans; Inactivation, Metabolic; Neoplasms; Platinum; Signal Transduction

1994
Mechanistic insight from kinetic studies on the interaction of model palladium (II) complexes with nucleic acid components.
    Metal ions in biological systems, 1996, Volume: 32

    Topics: Antineoplastic Agents; Carboplatin; Cisplatin; Drug Design; Humans; Kinetics; Neoplasms; Nucleosides; Nucleotides; Palladium; Platinum; Purines; Pyrimidines

1996
[Platinum compounds in cancer therapy--past, present, and future].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Cisplatin; Forecasting; Humans; Irinotecan; Medical Oncology; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Platinum

2001
Towards selectivity in cancer chemotherapy: a biochemical overview.
    Advances in enzyme regulation, 1978, Volume: 17

    Topics: Adenosine Deaminase Inhibitors; Animals; Antineoplastic Agents; Drug Administration Schedule; Folic Acid Antagonists; Humans; Methotrexate; Neoplasm Proteins; Neoplasms; Platinum; Protein Biosynthesis; Transcription, Genetic; Triazenes; Triazines

1978
Clinical pharmacokinetics of carboplatin.
    Clinical pharmacokinetics, 1991, Volume: 21, Issue:4

    Topics: Administration, Oral; Animals; Blood Proteins; Bone Marrow; Carboplatin; Cisplatin; Humans; Injections, Intraperitoneal; Injections, Intravenous; Neoplasms; Platinum; Protein Binding; Tissue Distribution

1991
Alkylating agents and platinum: is clinical resistance simply a tumor cell phenomenon?
    Current opinion in oncology, 1991, Volume: 3, Issue:6

    Topics: Alkylating Agents; DNA Damage; Drug Resistance; Humans; Leukocytes; Neoplasms; Platinum

1991
Cancer risk from inorganics.
    Cancer metastasis reviews, 1987, Volume: 6, Issue:2

    Topics: Animals; Biological Availability; Chromosome Aberrations; DNA; DNA Damage; Humans; Keratins; Lithium; Metals; Minerals; Mutation; Neoplasms; Platinum; Radioisotopes; Radiotherapy Dosage; Risk

1987
Radiation and platinum drug interaction.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1985, Volume: 48, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Survival; Chromosome Aberrations; Cisplatin; Combined Modality Therapy; DNA; Humans; In Vitro Techniques; Neoplasms; Neoplasms, Experimental; Oxygen; Platinum; Radiation-Sensitizing Agents; Structure-Activity Relationship; Sulfhydryl Compounds

1985
Carboplatin as a potentiator of radiation therapy.
    Cancer treatment reviews, 1985, Volume: 12 Suppl A

    Topics: Animals; Antineoplastic Agents; Carboplatin; Combined Modality Therapy; Cricetinae; Cricetulus; Humans; Mice; Neoplasms; Organoplatinum Compounds; Platinum; Radiation-Sensitizing Agents

1985

Trials

25 trial(s) available for platinum and Neoplasms

ArticleYear
Phase III Randomized Trial of Maintenance Taxanes Versus Surveillance in Women With Advanced Ovarian/Tubal/Peritoneal Cancer: A Gynecologic Oncology Group 0212:NRG Oncology Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2022, 12-10, Volume: 40, Issue:35

    Topics: Female; Humans; Medical Futility; Neoplasms; Platinum

2022
The effect of selenium yeast in the prevention of adverse reactions related to platinum-based combination therapy in patients with malignant tumors.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:21

    Topics: Antineoplastic Combined Chemotherapy Protocols; Humans; Neoplasms; Pain; Platinum; Quality of Life; Saccharomyces cerevisiae; Selenium

2023
Randomized pharmacokinetic study comparing subcutaneous and intravenous palonosetron in cancer patients treated with platinum based chemotherapy.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Administration, Intravenous; Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Injections, Subcutaneous; Isoquinolines; Male; Middle Aged; Neoplasms; Palonosetron; Platinum; Quinuclidines; Treatment Outcome; Vomiting

2014
Phase I trial of volasertib, a Polo-like kinase inhibitor, plus platinum agents in solid tumors: safety, pharmacokinetics and activity.
    Investigational new drugs, 2015, Volume: 33, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cell Cycle Proteins; Cisplatin; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Platinum; Polo-Like Kinase 1; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pteridines; Young Adult

2015
Phase I and pharmacokinetic evaluation of the anti-telomerase agent KML-001 with cisplatin in advanced solid tumors.
    Cancer chemotherapy and pharmacology, 2016, Volume: 78, Issue:5

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic; Arsenites; Cisplatin; Endpoint Determination; Enzyme Inhibitors; Female; Humans; Long QT Syndrome; Male; Middle Aged; Neoplasms; Platinum; Sodium Compounds; Telomerase; Treatment Outcome

2016
Long-term platinum retention after treatment with cisplatin and oxaliplatin.
    BMC clinical pharmacology, 2008, Sep-17, Volume: 8

    Topics: Aging; Antineoplastic Agents; Cisplatin; DNA Adducts; Female; Glomerular Filtration Rate; Humans; Male; Middle Aged; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Platinum; Time Factors; Tissue Distribution

2008
Phase I clinical trial of the novel platin complex dicycloplatin: clinical and pharmacokinetic results.
    International journal of clinical pharmacology and therapeutics, 2013, Volume: 51, Issue:2

    Topics: Adult; Aged; Anemia; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; China; Cyclobutanes; Dicarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Nausea; Neoplasms; Neutropenia; Platinum; Thrombocytopenia; Vomiting

2013
A phase I and pharmacologic study of pyrazoloacridine (NSC 366140) and carboplatin in patients with advanced cancer.
    Investigational new drugs, 2002, Volume: 20, Issue:3

    Topics: Acridines; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carboplatin; DNA Adducts; Drug Interactions; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasms; Neutropenia; Platinum; Pyrazoles

2002
A Phase I and pharmacological study of the platinum polymer AP5280 given as an intravenous infusion once every 3 weeks in patients with solid tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, May-15, Volume: 10, Issue:10

    Topics: Acrylamides; Adult; Aged; Antineoplastic Agents; Area Under Curve; Cisplatin; DNA; Dose-Response Relationship, Drug; Drug Delivery Systems; Female; Humans; Male; Middle Aged; Models, Chemical; Neoplasms; Organoplatinum Compounds; Platinum; Polymers; Time Factors

2004
Effects of early intervention with epoetin alfa on transfusion requirement, hemoglobin level and survival during platinum-based chemotherapy: Results of a multicenter randomised controlled trial.
    European journal of cancer (Oxford, England : 1990), 2005, Volume: 41, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Anemia; Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Epoetin Alfa; Erythropoietin; Female; Hematinics; Hemoglobins; Humans; Male; Middle Aged; Neoplasms; Platinum; Quality of Life; Recombinant Proteins; Survival Analysis

2005
Coadministration of oxaliplatin does not influence the pharmacokinetics of gemcitabine.
    Anti-cancer drugs, 2006, Volume: 17, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Deoxycytidine; Drug Interactions; Female; Gemcitabine; Humans; Male; Middle Aged; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Platinum; Treatment Outcome

2006
Phase I and pharmacokinetic trial of AP5346, a DACH-platinum-polymer conjugate, administered weekly for three out of every 4 weeks to advanced solid tumor patients.
    Cancer chemotherapy and pharmacology, 2007, Volume: 60, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Drug Administration Schedule; Drug Evaluation; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Platinum; Polymers

2007
Platinum compounds in cancer chemotherapy.
    Biochemistry and experimental biology, 1980, Volume: 16, Issue:2

    Topics: Animals; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Cytoskeleton; DNA; DNA Replication; Doxorubicin; Drug Therapy, Combination; Humans; Lethal Dose 50; Models, Molecular; Neoplasms; Platinum; Sarcoma, Experimental; Tissue Distribution

1980
Cisplatin disposition in children and adolescents with cancer.
    Cancer chemotherapy and pharmacology, 1981, Volume: 6, Issue:1

    Topics: Adolescent; Child; Cisplatin; Creatinine; Drug Evaluation; Humans; Kinetics; Neoplasms; Platinum

1981
Phase I study of WR-2721 and carboplatin.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:8

    Topics: Adult; Aged; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Female; Humans; Male; Middle Aged; Neoplasms; Neutropenia; Platinum; Thrombocytopenia

1993
Pharmacokinetics of elemental platinum (ultrafiltrate and total) after a thirty minute intravenous infusion of ormaplatin.
    Biopharmaceutics & drug disposition, 1997, Volume: 18, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Female; Hemofiltration; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Organoplatinum Compounds; Platinum

1997
Influence of amifostine on the pharmacokinetics of cisplatin in cancer patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:2

    Topics: Adult; Aged; Amifostine; Antineoplastic Agents; Cisplatin; DNA Adducts; Drug Interactions; Female; Half-Life; Hemofiltration; Humans; Leukocytes; Male; Middle Aged; Neoplasms; Platinum; Radiation-Protective Agents

1998
Inductively coupled plasma mass spectroscopy quantitation of platinum-DNA adducts in peripheral blood leukocytes of patients receiving cisplatin- or carboplatin-based chemotherapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1996, Volume: 2, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents; Carboplatin; Cisplatin; DNA Adducts; Female; Humans; Leukocytes, Mononuclear; Male; Mass Spectrometry; Middle Aged; Neoplasms; Platinum

1996
Pharmacokinetics and pharmacodynamics of lobaplatin (D-19466) in patients with advanced solid tumors, including patients with impaired renal of liver function.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents; Creatinine; Cyclobutanes; Erythrocytes; Female; Half-Life; Humans; Kidney Diseases; Liver Diseases; Male; Middle Aged; Neoplasms; Organoplatinum Compounds; Platelet Count; Platinum; Stereoisomerism

1999
A report of the clinical use of the detach-18 mechanical detachable platinum coil in 41 patients.
    AJNR. American journal of neuroradiology, 2001, Volume: 22, Issue:2

    Topics: Adult; Aged; Carotid Artery, Internal; Cerebral Angiography; Cerebrovascular Disorders; Embolization, Therapeutic; Equipment Design; Female; Humans; Male; Middle Aged; Neoplasms; Platinum

2001
Phase I and pharmacokinetic study of SPI-77, a liposomal encapsulated dosage form of cisplatin.
    Cancer chemotherapy and pharmacology, 2002, Volume: 49, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Capsules; Cisplatin; DNA Adducts; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Half-Life; Humans; Male; Middle Aged; Neoplasms; Platinum; Safety; Spectrophotometry, Atomic

2002
Comparable efficacy of epoetin alfa for anemic cancer patients receiving platinum- and nonplatinum-based chemotherapy: a retrospective subanalysis of two large, community-based trials.
    The oncologist, 2002, Volume: 7, Issue:2

    Topics: Anemia; Blood Transfusion; Disease Progression; Dose-Response Relationship, Drug; Epoetin Alfa; Erythropoietin; Female; Follow-Up Studies; Hematinics; Hematologic Neoplasms; Hemoglobins; Humans; Male; Middle Aged; Neoplasms; Platinum; Predictive Value of Tests; Prognosis; Quality of Life; Recombinant Proteins; Retrospective Studies; Sensitivity and Specificity; Time Factors; Treatment Outcome

2002
Pharmacokinetics of oxaliplatin (NSC 266046) alone and in combination with paclitaxel in cancer patients.
    Cancer chemotherapy and pharmacology, 2002, Volume: 49, Issue:5

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Area Under Curve; DNA Adducts; Dose-Response Relationship, Drug; Drug Interactions; Head and Neck Neoplasms; Humans; Leukocytes; Mass Spectrometry; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Platinum; Reproducibility of Results

2002
Platinum-DNA damage in leukocyte DNA of patients receiving carboplatin and cisplatin chemotherapy, measured by atomic absorption spectrometry.
    Carcinogenesis, 1991, Volume: 12, Issue:7

    Topics: Carboplatin; Cisplatin; DNA; DNA Damage; Double-Blind Method; Drug Administration Schedule; Female; Humans; Leukocytes; Male; Neoplasms; Platinum; Prospective Studies; Spectrophotometry, Atomic

1991
Phase I trial of 5-day continuous venous infusion of oxaliplatin at circadian rhythm-modulated rate compared with constant rate.
    Journal of the National Cancer Institute, 1990, Jun-20, Volume: 82, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents; Circadian Rhythm; Drug Administration Schedule; Drug Evaluation; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Platinum

1990

Other Studies

341 other study(ies) available for platinum and Neoplasms

ArticleYear
Linear-Dendritic Polymer-Platinum Complexes Forming Well-Defined Nanocapsules for Acid-Responsive Drug Delivery.
    ACS applied materials & interfaces, 2021, Sep-22, Volume: 13, Issue:37

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cisplatin; Coordination Complexes; Dendrimers; Drug Carriers; Drug Liberation; Humans; Mice, Inbred BALB C; Nanocapsules; Neoplasms; Platinum; Polyethylene Glycols; Polylysine; Xenograft Model Antitumor Assays

2021
In vitro and in vivoactivity of series of cationic dinuclearPt(II) complexes.
    Journal of inorganic biochemistry, 2021, Volume: 225

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Coordination Complexes; Drug Screening Assays, Antitumor; G2 Phase Cell Cycle Checkpoints; Ligands; Male; Mice, Inbred BALB C; Molecular Structure; Neoplasm Metastasis; Neoplasms; Platinum

2021
Biomimetic Platform Based on Mesoporous Platinum for Multisynergistic Cancer Therapy.
    ACS biomaterials science & engineering, 2021, 11-08, Volume: 7, Issue:11

    Topics: Antineoplastic Agents; Biomimetics; Humans; Metal Nanoparticles; Neoplasms; Platinum

2021
Distinct mechanism of action for antitumoral neutral cyclometalated Pt(II)-complexes bearing antifungal imidazolyl-based drugs.
    Journal of inorganic biochemistry, 2022, Volume: 226

    Topics: A549 Cells; Antifungal Agents; Antineoplastic Agents; Apoptosis; Coordination Complexes; G1 Phase; Humans; Neoplasms; Platinum; Resting Phase, Cell Cycle

2022
ERCC1 19007 Polymorphism in Greek Patients with Advanced Urothelial Cancer Treated with Platinum-Based Chemotherapy: Effect of the Changing Treatment Paradigm: A Cohort Study by the Hellenic GU Cancer Group.
    Current oncology (Toronto, Ont.), 2021, 11-05, Volume: 28, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; DNA-Binding Proteins; Endonucleases; Female; Greece; Humans; Neoplasms; Platinum

2021
Platinum(IV) complexes as inhibitors of CD47-SIRPα axis for chemoimmunotherapy of cancer.
    European journal of medicinal chemistry, 2022, Feb-05, Volume: 229

    Topics: Animals; Antigens, Differentiation; Antineoplastic Agents; CD47 Antigen; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Coordination Complexes; Drug Screening Assays, Antitumor; Humans; Immune Checkpoint Inhibitors; Leukocytes, Mononuclear; Mice; Mice, Inbred ICR; Neoplasms; Phagocytosis; Platinum; Reactive Oxygen Species; Receptors, Immunologic

2022
Influence of ligand lipophilicity in Pt(II) complexes on their antiproliferative and apoptotic activities in tumour cell lines.
    Journal of inorganic biochemistry, 2022, Volume: 227

    Topics: Antineoplastic Agents; Cell Proliferation; Coordination Complexes; Drug Screening Assays, Antitumor; HeLa Cells; HL-60 Cells; Humans; Neoplasms; Platinum; U937 Cells

2022
A Nonenzymatic Hydrogen Peroxide Electrochemical Sensing and Application in Cancer Diagnosis.
    Small methods, 2021, Volume: 5, Issue:5

    Topics: Biomarkers, Tumor; Electrochemical Techniques; Graphite; Humans; Hydrogen Peroxide; Limit of Detection; Nanocomposites; Neoplasms; Nickel; Nitrogen; Platinum

2021
KCl-CaCO
    Biomaterials science, 2022, Jan-18, Volume: 10, Issue:2

    Topics: Calcium Carbonate; Humans; Metal Nanoparticles; Nanoparticles; Neoplasms; Platinum; Potassium Chloride

2022
Ultra-Small Platinum Nanoparticle-Enabled Catalysis and Corrosion Susceptibility Reverse Tumor Hypoxia for Cancer Chemoimmunotherapy.
    ACS applied bio materials, 2021, 08-16, Volume: 4, Issue:8

    Topics: Catalysis; Corrosion; Humans; Hypoxia; Immune Checkpoint Proteins; Immunotherapy; Metal Nanoparticles; Neoplasms; Oxygen; Platinum; Reactive Oxygen Species; Tumor Hypoxia

2021
Epigenetic Platinum Complexes Breaking the "Eat Me/Don't Eat Me" Balance for Enhanced Cancer Chemoimmunotherapy.
    Bioconjugate chemistry, 2022, 02-16, Volume: 33, Issue:2

    Topics: Epigenesis, Genetic; Humans; Neoplasms; Nitric Oxide; Phagocytosis; Platinum; Tumor Microenvironment

2022
A multifunctional platinum(IV) and cyanine dye-based polyprodrug for trimodal imaging-guided chemo-phototherapy.
    Journal of materials chemistry. B, 2022, 02-16, Volume: 10, Issue:7

    Topics: Animals; Coloring Agents; Drug Delivery Systems; Mice; Neoplasms; Phototherapy; Platinum; Prodrugs

2022
ROS-Activated nanoscale coordination polymers for enhanced ultrasound-mediated therapy for the treatment of cancer.
    Acta biomaterialia, 2022, 04-15, Volume: 143

    Topics: Cell Line, Tumor; Doxorubicin; Humans; Nanoparticles; Neoplasms; Platinum; Polymers; Porphyrins; Reactive Oxygen Species

2022
Metal-Organic Framework-Based Nanoheater with Photo-Triggered Cascade Effects for On-Demand Suppression of Cellular Thermoresistance and Synergistic Cancer Therapy.
    Advanced healthcare materials, 2022, Volume: 11, Issue:13

    Topics: Hyperthermia, Induced; Metal Nanoparticles; Metal-Organic Frameworks; Nanoparticles; Neoplasms; Phototherapy; Platinum; Theranostic Nanomedicine

2022
Enhancing Circulation and Tumor Accumulation of Carboplatin via an Erythrocyte-Anchored Prodrug Strategy.
    Angewandte Chemie (International ed. in English), 2022, 06-20, Volume: 61, Issue:25

    Topics: Animals; Antineoplastic Agents; Carboplatin; Cell Line, Tumor; Cisplatin; Erythrocytes; Mice; Neoplasms; Platinum; Prodrugs

2022
Metal-based Complexes as Potential Anti-cancer Agents.
    Anti-cancer agents in medicinal chemistry, 2022, 08-04, Volume: 22, Issue:15

    Topics: Antineoplastic Agents; Cisplatin; Coordination Complexes; Humans; Neoplasms; Platinum; Ruthenium

2022
Iodine Conjugated Pt(IV) Nanoparticles for Precise Chemotherapy with Iodine-Pt Guided Computed Tomography Imaging and Biotin-Mediated Tumor-Targeting.
    ACS nano, 2022, 04-26, Volume: 16, Issue:4

    Topics: Antineoplastic Agents; Biotin; Cell Line, Tumor; Cisplatin; Humans; Iodine; Nanoparticles; Neoplasms; Platinum; Theranostic Nanomedicine; Tissue Distribution; Tomography, X-Ray Computed

2022
Similarities in the Neuropathy Phenotype of Cancer Survivors Who Received Different Classes of Chemotherapy Drugs.
    The journal of pain, 2022, Volume: 23, Issue:9

    Topics: Antineoplastic Agents; Cancer Survivors; Humans; Neoplasms; Pain; Peripheral Nervous System Diseases; Phenotype; Platinum; Quality of Life; Taxoids

2022
Nanosized Janus AuNR-Pt Motor for Enhancing NIR-II Photoacoustic Imaging of Deep Tumor and Pt
    ACS nano, 2022, 05-24, Volume: 16, Issue:5

    Topics: Gold; Humans; Hydrogen Peroxide; Neoplasms; Photoacoustic Techniques; Platinum

2022
Self-assembled Pt(II) metallacycles enable precise cancer combination chemotherapy.
    Proceedings of the National Academy of Sciences of the United States of America, 2022, 05-17, Volume: 119, Issue:20

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Liberation; Drug Synergism; Folic Acid; Humans; Mice; Nanoparticles; Neoplasms; Platinum; Polymers; Stilbenes; Tumor Microenvironment

2022
A platinum nanourchin-based multi-enzymatic platform to disrupt mitochondrial function assisted by modulating the intracellular H
    Biomaterials, 2022, Volume: 286

    Topics: Cell Line, Tumor; Glucose; Glucose Oxidase; Homeostasis; Humans; Hydrogen Peroxide; Manganese; Mitochondria; Neoplasms; Platinum; Reactive Oxygen Species; Tumor Microenvironment

2022
Platinum-Based Two-Photon Photosensitizer Responsive to NIR Light in Tumor Hypoxia Microenvironment.
    Journal of medicinal chemistry, 2022, 06-09, Volume: 65, Issue:11

    Topics: Animals; Cell Line, Tumor; Hypoxia; Mice; Naphthalimides; Neoplasms; Photochemotherapy; Photosensitizing Agents; Platinum; Reactive Oxygen Species; Tumor Hypoxia; Tumor Microenvironment

2022
A phenolic based tumor-permeated nano-framework for immunogenic cell death induction combined with PD-L1 immune checkpoint blockade.
    Biomaterials science, 2022, Jul-12, Volume: 10, Issue:14

    Topics: Antineoplastic Agents; B7-H1 Antigen; Cell Line, Tumor; Humans; Immune Checkpoint Inhibitors; Immunogenic Cell Death; Immunotherapy; Metal Nanoparticles; Neoplasms; Platinum; Programmed Cell Death 1 Receptor

2022
Severity of hearing loss after platinum chemotherapy in childhood cancer survivors.
    Pediatric blood & cancer, 2022, Volume: 69, Issue:9

    Topics: Antineoplastic Agents; Cancer Survivors; Carboplatin; Child; Cisplatin; Hearing Loss; Humans; Neoplasms; Platinum

2022
Poly(β-cyclodextrin)/platinum prodrug supramolecular nano system for enhanced cancer therapy: Synthesis and in vivo study.
    Carbohydrate polymers, 2022, Sep-15, Volume: 292

    Topics: Animals; Antineoplastic Agents; beta-Cyclodextrins; Cell Line, Tumor; Cisplatin; Mice; Neoplasms; Platinum; Prodrugs; Propylene Glycols

2022
Natural Polyphenols-Platinum Nanocomplexes Stimulate Immune System for Combination Cancer Therapy.
    Nano letters, 2022, 07-13, Volume: 22, Issue:13

    Topics: Cell Line, Tumor; Humans; Immunotherapy; Neoplasms; Platinum; Polyphenols; Reproducibility of Results; T-Lymphocytes, Cytotoxic; Tumor Microenvironment

2022
Tumor microenvironment-activated single-atom platinum nanozyme with H
    Theranostics, 2022, Volume: 12, Issue:11

    Topics: Catalysis; Cell Line, Tumor; Chemoradiotherapy; Glutathione; Humans; Hydrogen Peroxide; Neoplasms; Oxygen; Platinum; Reactive Oxygen Species; Tumor Microenvironment

2022
A Porous Bimetallic Au@Pt Core-Shell Oxygen Generator to Enhance Hypoxia-Dampened Tumor Chemotherapy Synergized with NIR-II Photothermal Therapy.
    ACS nano, 2022, 07-26, Volume: 16, Issue:7

    Topics: Cell Line, Tumor; Doxorubicin; Gold; Humans; Hydrogen Peroxide; Hypoxia; Neoplasms; Oxygen; Photothermal Therapy; Platinum; Porosity

2022
Genetically Engineered Nanoparticles of Asymmetric Triblock Polypeptide with a Platinum(IV) Cargo Outperforms a Platinum(II) Analog and Free Drug in a Murine Cancer Model.
    Nano letters, 2022, 07-27, Volume: 22, Issue:14

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Mice; Nanoparticles; Neoplasms; Peptides; Platinum; Prodrugs

2022
Phenylthiol-BODIPY-based supramolecular metallacycles for synergistic tumor chemo-photodynamic therapy.
    Proceedings of the National Academy of Sciences of the United States of America, 2022, 07-19, Volume: 119, Issue:29

    Topics: Boron Compounds; Cell Line, Tumor; Coordination Complexes; Drug Synergism; Humans; Neoplasms; Photochemotherapy; Platinum; Porphobilinogen

2022
Potential Anticancer Activities and Catalytic Oxidation Efficiency of Platinum(IV) Complex.
    Molecules (Basel, Switzerland), 2022, Jul-09, Volume: 27, Issue:14

    Topics: Antineoplastic Agents; Crystallography, X-Ray; Humans; Ligands; Neoplasms; Platinum; Spectroscopy, Fourier Transform Infrared

2022
Cancer survivors and neurotoxic chemotherapy: hearing loss and tinnitus.
    BMJ supportive & palliative care, 2023, Volume: 13, Issue:3

    Topics: Cancer Survivors; Hearing Loss; Humans; Neoplasms; Nutrition Surveys; Platinum; Taxoids; Tinnitus; United States

2023
Sensitization of cancer cells towards Cisplatin and Carboplatin by protein kinase D inhibitors through modulation of ATP7A/B (copper transport ATPases).
    Cancer treatment and research communications, 2022, Volume: 32

    Topics: Adenosine Triphosphatases; Antineoplastic Agents; Carboplatin; Cation Transport Proteins; Cisplatin; Copper; Copper-Transporting ATPases; Drug Resistance, Neoplasm; Humans; Neoplasms; Peptide Fragments; Platinum; Protein Kinase C; Protein Kinase Inhibitors

2022
Ruthenium(II) Polypyridyl Complexes Containing Simple Dioxo Ligands: a Structure-Activity Relationship Study Shows the Importance of the Charge.
    Chembiochem : a European journal of chemical biology, 2022, 10-06, Volume: 23, Issue:19

    Topics: Antineoplastic Agents; Carboplatin; Cisplatin; Coordination Complexes; Humans; Ligands; Malonates; Neoplasms; Oxalates; Platinum; Ruthenium; Structure-Activity Relationship

2022
Platinum-based nanocomposites loaded with MTH1 inhibitor amplify oxidative damage for cancer therapy.
    Colloids and surfaces. B, Biointerfaces, 2022, Volume: 218

    Topics: Arginine; Aspartic Acid; Catalase; Cell Line, Tumor; Glycine; Humans; Hydrogen Peroxide; Liposomes; Metal Nanoparticles; Nanocomposites; Nanoparticles; Neoplasms; Nucleotides; Oligopeptides; Oxidative Stress; Oxygen; Photochemotherapy; Photosensitizing Agents; Platinum; Reactive Oxygen Species; Silicon Dioxide; Singlet Oxygen

2022
Simultaneous Photoactivation of cGAS-STING Pathway and Pyroptosis by Platinum(II) Triphenylamine Complexes for Cancer Immunotherapy.
    Angewandte Chemie (International ed. in English), 2022, Oct-24, Volume: 61, Issue:43

    Topics: Antiviral Agents; DNA; Immunotherapy; Interferons; Membrane Proteins; Neoplasms; Nucleotidyltransferases; Platinum; Pyroptosis; Signal Transduction

2022
Amlexanox-modified platinum(IV) complex triggers apoptotic and autophagic bimodal death of cancer cells.
    European journal of medicinal chemistry, 2022, Nov-15, Volume: 242

    Topics: Aminopyridines; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; bcl-2-Associated X Protein; Cell Line, Tumor; Cisplatin; Cytochromes c; DNA; Humans; Microtubule-Associated Proteins; Neoplasms; Platinum; Prodrugs

2022
Pharmacokinetics derived from PET imaging of inspiring radio-enhancer platinum nanoparticles.
    Nanomedicine : nanotechnology, biology, and medicine, 2022, Volume: 46

    Topics: Humans; Metal Nanoparticles; Nanoparticles; Neoplasms; Platinum; Positron-Emission Tomography; Tissue Distribution

2022
2D Copper(II) Metalated Metal-Organic Framework Nanocomplexes for Dual-enhanced Photodynamic Therapy and Amplified Antitumor Immunity.
    ACS applied materials & interfaces, 2022, Oct-05, Volume: 14, Issue:39

    Topics: Catalase; Cell Line, Tumor; Copper; Folic Acid; Humans; Hydrogen Peroxide; Metal Nanoparticles; Metal-Organic Frameworks; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Platinum; Reactive Oxygen Species; Tumor Microenvironment

2022
Trans-[bis(benzimidazol-2-ylidene)dichlorido]platinum(II) complexes with peculiar modes of action and activity against cisplatin-resistant cancer cells.
    Journal of inorganic biochemistry, 2023, Volume: 238

    Topics: Antineoplastic Agents; Cell Cycle; Cisplatin; Humans; Neoplasms; Platinum

2023
Albumin-templated platinum (II) sulfide nanodots for size-dependent cancer theranostics.
    Acta biomaterialia, 2023, 01-01, Volume: 155

    Topics: Albumins; Cell Line, Tumor; Humans; Nanoparticles; Neoplasms; Photoacoustic Techniques; Phototherapy; Platinum; Precision Medicine; Sulfides; Theranostic Nanomedicine

2023
Platinum-Coordinated Dual-Responsive Nanogels for Universal Drug Delivery and Combination Cancer Therapy.
    Small (Weinheim an der Bergstrasse, Germany), 2022, Volume: 18, Issue:46

    Topics: Cisplatin; Drug Delivery Systems; Nanogels; Neoplasms; Platinum; Polyethylene Glycols; Polyethyleneimine

2022
Exosomes loaded with ultrasmall Pt nanoparticles: a novel low-toxicity alternative to cisplatin.
    Journal of nanobiotechnology, 2022, Nov-05, Volume: 20, Issue:1

    Topics: Cell Line, Tumor; Cisplatin; Exosomes; Humans; Metal Nanoparticles; Nanoparticles; Neoplasms; Platinum

2022
Platinum-induced ototoxicity in pediatric cancer survivors: GSTP1 c.313A>G variant association.
    Medicine, 2022, Nov-11, Volume: 101, Issue:45

    Topics: Cancer Survivors; Carboplatin; Child; Cisplatin; Cross-Sectional Studies; Deafness; Glutathione S-Transferase pi; Hearing Loss; Humans; Neoplasms; Ototoxicity; Platinum

2022
A nuclease-mimetic platinum nanozyme induces concurrent DNA platination and oxidative cleavage to overcome cancer drug resistance.
    Nature communications, 2022, 11-30, Volume: 13, Issue:1

    Topics: Cisplatin; DNA; DNA Adducts; Drug Resistance, Neoplasm; Endonucleases; Neoplasms; Nucleotides; Oxidative Stress; Platinum

2022
Multi-specific niflumic acid platinum(IV) complexes displaying potent antitumor activities by improving immunity and suppressing angiogenesis besides causing DNA damage.
    Dalton transactions (Cambridge, England : 2003), 2022, Dec-20, Volume: 52, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cisplatin; DNA Damage; Humans; Inflammation; Neoplasms; Niflumic Acid; Organoplatinum Compounds; Platinum

2022
Rational Design of Platinum-Bismuth Sulfide Schottky Heterostructure for Sonocatalysis-Mediated Hydrogen Therapy.
    Advanced materials (Deerfield Beach, Fla.), 2023, Volume: 35, Issue:10

    Topics: Cell Line, Tumor; Glutathione; Humans; Hydrogen Peroxide; Nanoparticles; Neoplasms; Oxygen; Platinum; Tumor Microenvironment

2023
Hydrogen Bonding Nanoarchitectonics of Organic Pigment-Based Janus Microrobots with Entering Capability into Cancer Cells.
    ACS nano, 2023, 01-10, Volume: 17, Issue:1

    Topics: Animals; Coloring Agents; Hydrogen Bonding; Indigo Carmine; Mice; Neoplasms; Platinum

2023
    Journal of medicinal chemistry, 2023, 01-12, Volume: 66, Issue:1

    Topics: B7-H1 Antigen; Cell Cycle Proteins; Cell Line, Tumor; Cytoplasm; Drug-Related Side Effects and Adverse Reactions; Humans; Immunotherapy; Neoplasms; Nuclear Proteins; Platinum; Prodrugs; Transcription Factors; Tumor Microenvironment

2023
Copy number footprints of platinum-based anticancer therapies.
    PLoS genetics, 2023, Volume: 19, Issue:2

    Topics: Antineoplastic Agents; Chromosome Aberrations; DNA Copy Number Variations; Humans; Mutation; Neoplasms; Platinum

2023
A Bio-Liposome Activating Natural Killer Cell by Illuminating Tumor Homogenization Antigen Properties.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:12

    Topics: Animals; Antigens, Neoplasm; Cell Line, Tumor; Humans; Killer Cells, Natural; Liposomes; Mice; Neoplasms; Platinum

2023
BRCA1/ATF1-Mediated Transactivation is Involved in Resistance to PARP Inhibitors and Cisplatin.
    Cancer research communications, 2021, Volume: 1, Issue:2

    Topics: Activating Transcription Factor 1; BRCA1 Protein; Cisplatin; Drug Resistance, Neoplasm; Genes, BRCA1; Humans; Neoplasms; Platinum; Poly(ADP-ribose) Polymerase Inhibitors; Transcriptional Activation

2021
Reduction of Platinum(IV) Prodrug Hemoglobin Nanoparticles with Deeply Penetrating Ultrasound Radiation for Tumor-Targeted Therapeutically Enhanced Anticancer Therapy.
    Angewandte Chemie (International ed. in English), 2023, 05-22, Volume: 62, Issue:22

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Mice; Nanoparticles; Neoplasms; Platinum; Prodrugs; Tumor Microenvironment

2023
Platinum-Coordinated Engineered Nanoreactors with O
    ACS applied materials & interfaces, 2023, Apr-12, Volume: 15, Issue:14

    Topics: Antineoplastic Agents; Cell Line, Tumor; Humans; Hydrogen Peroxide; Hypoxia; Nanoparticles; Nanotechnology; Neoplasms; Photochemotherapy; Photosensitizing Agents; Platinum; Tumor Microenvironment

2023
Pt nanozyme-bridged covalent organic framework-aptamer nanoplatform for tumor targeted self-strengthening photocatalytic therapy.
    Biomaterials, 2023, Volume: 297

    Topics: Animals; Catalase; Cell Line, Tumor; Hydrogen Peroxide; Metal Nanoparticles; Metal-Organic Frameworks; Mice; Nanoparticles; Neoplasms; Photochemotherapy; Platinum; Tumor Microenvironment

2023
Synthesis of single-walled carbon nanotubes functionalized with platinum nanoparticles to sense breast cancer cells in 4T1 model to X-ray radiation.
    Mikrochimica acta, 2023, 04-18, Volume: 190, Issue:5

    Topics: Animals; Cell Line; Metal Nanoparticles; Mice; Nanotubes, Carbon; Neoplasms; Platinum; Serum Albumin, Bovine; X-Rays

2023
Developing an Anticancer Platinum(II) Compound Based on the Uniqueness of Human Serum Albumin.
    Journal of medicinal chemistry, 2023, 04-27, Volume: 66, Issue:8

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Delivery Systems; Humans; Neoplasms; Platinum; Serum Albumin, Human

2023
Chemodynamic/Photothermal Synergistic Cancer Immunotherapy Based on Yeast Microcapsule-Derived Au/Pt Nanoparticles.
    ACS applied materials & interfaces, 2023, May-24, Volume: 15, Issue:20

    Topics: Animals; Capsules; Cell Line, Tumor; Gold; Immunotherapy; Metal Nanoparticles; Mice; Nanoparticles; Neoplasms; Phototherapy; Platinum; Saccharomyces cerevisiae; Tumor Microenvironment

2023
Synthesis and Characterisation of Fluorescent Novel Pt(II) Cyclometallated Complexes with Anticancer Activity.
    International journal of molecular sciences, 2023, Apr-28, Volume: 24, Issue:9

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Coordination Complexes; DNA; Humans; Neoplasms; Platinum

2023
Oxali(IV)Fluors: Fluorescence Responsive Oxaliplatin(IV) Complexes Identify a Hypoxia-Dependent Reduction in Cancer Cells.
    Journal of the American Chemical Society, 2023, 06-21, Volume: 145, Issue:24

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Fluorescence; Neoplasms; Oxalidaceae; Oxaliplatin; Platinum; Prodrugs

2023
Platinum(IV) Derivatives of [Pt(1
    Journal of medicinal chemistry, 2023, 06-22, Volume: 66, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Line, Tumor; Diclofenac; Ligands; Neoplasms; Organoplatinum Compounds; Platinum; Prodrugs

2023
The Power of Kinetic Inertness in Improving Platinum Anticancer Therapy by Circumventing Resistance and Ameliorating Nephrotoxicity.
    Angewandte Chemie (International ed. in English), 2023, 09-18, Volume: 62, Issue:38

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Humans; Kinetics; Neoplasms; Platinum

2023
An ultrasound-activatable platinum prodrug for sono-sensitized chemotherapy.
    Science advances, 2023, 06-23, Volume: 9, Issue:25

    Topics: Antineoplastic Agents; Cell Line, Tumor; Humans; Neoplasms; Platinum; Prodrugs

2023
Near-infrared-activated anticancer platinum(IV) complexes directly photooxidize biomolecules in an oxygen-independent manner.
    Nature chemistry, 2023, Volume: 15, Issue:7

    Topics: Antineoplastic Agents; Cell Line, Tumor; Humans; Light; Neoplasms; Oxygen; Platinum

2023
Pulsed sonodynamic therapy of melanoma cancer cells using nanoparticles of and mesoporous platinum.
    Ultrasound in medicine & biology, 2023, Volume: 49, Issue:9

    Topics: Cell Line, Tumor; Humans; Melanoma; Metal Nanoparticles; Nanoparticles; Nanostructures; Neoplasms; Platinum; Reactive Oxygen Species; Ultrasonic Therapy

2023
Mitochondria-Targeting Upconversion Nanoparticles@MOF for Multiple-Enhanced Photodynamic Therapy in Hypoxic Tumor.
    ACS applied materials & interfaces, 2023, Aug-02, Volume: 15, Issue:30

    Topics: Cell Line, Tumor; Humans; Hydrogen Peroxide; Metal Nanoparticles; Metal-Organic Frameworks; Mitochondria; Nanoparticles; Neoplasms; Oxygen; Photochemotherapy; Photosensitizing Agents; Platinum; Reactive Oxygen Species

2023
Dual Synergistic Tumor-Specific Polymeric Nanoparticles for Efficient Chemo-Immunotherapy.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:29

    Topics: B7-H1 Antigen; Humans; Immunotherapy; Nanoparticles; Neoplasms; Platinum; Polymers

2023
The mechanism of antiproliferative activity of the oxaliplatin pyrophosphate derivative involves its binding to nuclear DNA in cancer cells.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2023, Volume: 28, Issue:7

    Topics: Antineoplastic Agents; Cisplatin; Diphosphates; DNA; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Platinum

2023
Drug-Primed Self-Assembly of Platinum-Single-Atom Nanozyme to Regulate Cellular Redox Homeostasis Against Cancer.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:30

    Topics: Glutathione; Homeostasis; Humans; Neoplasms; Oxidation-Reduction; Oxygen; Platinum; Tumor Microenvironment

2023
Insertion of (Bioactive) Equatorial Ligands into Platinum(IV) Complexes.
    Angewandte Chemie (International ed. in English), 2023, 11-13, Volume: 62, Issue:46

    Topics: Antineoplastic Agents; Cell Line, Tumor; Humans; Ligands; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Platinum; Prodrugs

2023
A Golgi-Targeted Platinum Complex Plays a Dual Role in Autophagy Regulation for Highly Efficient Cancer Therapy.
    Angewandte Chemie (International ed. in English), 2023, 10-26, Volume: 62, Issue:44

    Topics: Antineoplastic Agents; Autophagy; Cisplatin; Golgi Apparatus; Neoplasms; Platinum

2023
Defect-rich platinum-zinc oxide heterojunction as a potent ROS amplifier for synergistic sono-catalytic therapy.
    Acta biomaterialia, 2023, Volume: 171

    Topics: Catalase; Cell Line, Tumor; Glutathione; Humans; Hydrogen Peroxide; Neoplasms; Oxygen; Platinum; Reactive Oxygen Species; Singlet Oxygen; Ultrasonic Therapy; Zinc; Zinc Oxide

2023
Development of Prodrug-Payloads for Targeted Therapeutic Applications of Platinum-Acridine Anticancer Agents.
    Bioconjugate chemistry, 2023, 10-18, Volume: 34, Issue:10

    Topics: Acridines; Antineoplastic Agents; Humans; Neoplasms; Platinum; Prodrugs

2023
Study of anticancer effects of platinum levetiracetam and levetiracetam via cancer biomarkers genes expression on HepG2 cell line.
    Molecular biology reports, 2023, Volume: 50, Issue:11

    Topics: Anticonvulsants; Biomarkers, Tumor; Hep G2 Cells; Humans; Levetiracetam; MicroRNAs; Neoplasms; Platinum; Proto-Oncogene Proteins c-bcl-2; Telomerase

2023
H-Dot Mediated Nanotherapeutics Mitigate Systemic Toxicity of Platinum-Based Anticancer Drugs.
    International journal of molecular sciences, 2023, Oct-23, Volume: 24, Issue:20

    Topics: Animals; Antineoplastic Agents; Carboplatin; Cardiotoxicity; Cisplatin; Neoplasms; Platinum

2023
Analysis of platinum-based anticancer injections cisplatin and carboplatin in blood serum and urine of cancer patients by photometry, fluorometry, liquid chromatography using a Schiff-base as derivatizing reagent.
    Journal of pharmaceutical and biomedical analysis, 2024, Jan-20, Volume: 238

    Topics: Carboplatin; Chromatography, High Pressure Liquid; Cisplatin; Fluorometry; Humans; Indicators and Reagents; Ligands; Neoplasms; Platinum; Serum

2024
Platinum nanoparticle-anchored metal-organic complex nanospheres by a coordination-crystallization approach for enhanced sonodynamic therapy of tumors.
    Journal of materials chemistry. B, 2023, Dec-06, Volume: 11, Issue:47

    Topics: Coordination Complexes; Crystallization; Humans; Ions; Nanospheres; Neoplasms; Platinum

2023
CRISPR-Cas12a Coupled with Platinum Nanoreporter for Visual Quantification of SNVs on a Volumetric Bar-Chart Chip.
    Analytical chemistry, 2019, 10-01, Volume: 91, Issue:19

    Topics: CRISPR-Cas Systems; DNA, Single-Stranded; Feasibility Studies; Magnets; Metal Nanoparticles; Microspheres; Nanotechnology; Neoplasms; Platinum; Polymorphism, Single Nucleotide

2019
Cytotoxic activity of copper(ii), nickel(ii) and platinum(ii) thiosemicarbazone derivatives: interaction with DNA and the H2A histone peptide.
    Metallomics : integrated biometal science, 2019, 10-16, Volume: 11, Issue:10

    Topics: Antineoplastic Agents; Cell Line, Tumor; Coordination Complexes; Copper; DNA; Histones; Humans; Neoplasms; Nickel; Platinum; Thiosemicarbazones

2019
Monolithic chromatography on conjoint liquid chromatography columns for speciation of platinum-based chemotherapeutics in serum of cancer patients.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2020, Volume: 57

    Topics: Chromatography, Liquid; Humans; Immunoglobulin G; Neoplasms; Platinum; Reproducibility of Results; Serum Albumin

2020
First Attempts of the Use of
    Molecules (Basel, Switzerland), 2019, Nov-02, Volume: 24, Issue:21

    Topics: Coordination Complexes; Crystallography, X-Ray; Humans; Ligands; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Models, Molecular; Neoplasms; Oxidation-Reduction; Platinum; Thiazoles; Water

2019
New Platinum(II) Triazole Thiosemicarbazone Complexes: Analysis of Their Reactivity and Potential Antitumoral Action.
    Chembiochem : a European journal of chemical biology, 2020, 04-17, Volume: 21, Issue:8

    Topics: Antineoplastic Agents; Coordination Complexes; Hep G2 Cells; Humans; MCF-7 Cells; Neoplasms; Platinum; Thiosemicarbazones; Triazoles

2020
Integrating in situ formation of nanozymes with mesoporous polydopamine for combined chemo, photothermal and hypoxia-overcoming photodynamic therapy.
    Chemical communications (Cambridge, England), 2019, Dec-05, Volume: 55, Issue:98

    Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Chlorophyllides; Doxorubicin; Humans; Hydrogen Peroxide; Indoles; Lasers; Metal Nanoparticles; Mice; Neoplasms; Photochemotherapy; Platinum; Polymers; Porosity; Porphyrins; Serum Albumin, Bovine

2019
Sensitive measurement of tumor markers somatostatin receptors using an octreotide-directed Pt nano-flakes driven electrochemical sensor.
    Talanta, 2020, Feb-01, Volume: 208

    Topics: Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Biosensing Techniques; Electrochemical Techniques; Electrodes; Gold; HeLa Cells; Humans; Metal Nanoparticles; Neoplasms; Octreotide; Platinum; Receptors, Somatostatin

2020
The assembly and antitumor activity of lycium barbarum polysaccharide-platinum-based conjugates.
    Journal of inorganic biochemistry, 2020, Volume: 205

    Topics: A549 Cells; Antineoplastic Agents; DNA Damage; DNA, Neoplasm; Drugs, Chinese Herbal; G2 Phase Cell Cycle Checkpoints; Humans; MCF-7 Cells; Neoplasms; Platinum

2020
Novel nickel(II), palladium(II), and platinum(II) complexes having a pyrrolyl-iminophosphine (PNN) pincer: Synthesis, crystal structures, and cytotoxic activity.
    Journal of inorganic biochemistry, 2020, Volume: 205

    Topics: A549 Cells; Antineoplastic Agents; Coordination Complexes; Crystallography, X-Ray; Cytotoxins; Endoplasmic Reticulum Chaperone BiP; Heterocyclic Compounds; Humans; Molecular Docking Simulation; Molecular Structure; Neoplasms; Nickel; Palladium; Platinum

2020
A novel platinum-based chemotherapeutic inducing immunogenic cell death.
    Oncoimmunology, 2020, Volume: 9, Issue:1

    Topics: Antineoplastic Agents; Humans; Immunogenic Cell Death; Neoplasms; Platinum

2020
A Facile One-Pot Synthesis of Versatile PEGylated Platinum Nanoflowers and Their Application in Radiation Therapy.
    International journal of molecular sciences, 2020, Feb-27, Volume: 21, Issue:5

    Topics: Cell Death; Cytoplasm; HeLa Cells; Humans; Metal Nanoparticles; Microscopy, Electron, Transmission; Neoplasms; Particle Size; Platinum; Polyethylene Glycols; Polymers; Radiation-Sensitizing Agents; Water

2020
Polypeptide-Based Theranostics with Tumor-Microenvironment-Activatable Cascade Reaction for Chemo-ferroptosis Combination Therapy.
    ACS applied materials & interfaces, 2020, May-06, Volume: 12, Issue:18

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cisplatin; Coordination Complexes; Ferroptosis; Humans; Hydroxyl Radical; Magnetic Resonance Imaging; Magnetite Nanoparticles; Mice, Inbred BALB C; Neoplasms; Peptides; Platinum; Polyglutamic Acid; Polylysine; Precision Medicine; Prodrugs; Tumor Microenvironment; Xenograft Model Antitumor Assays

2020
Tetraphenylethene-Based Supramolecular Coordination Frameworks with Aggregation-Induced Emission for an Artificial Light-Harvesting System.
    ACS applied materials & interfaces, 2020, May-20, Volume: 12, Issue:20

    Topics: Benzylidene Compounds; Coordination Complexes; Fluorescent Dyes; HeLa Cells; Humans; Ligands; Light; Metal-Organic Frameworks; Microscopy, Confocal; Microscopy, Fluorescence; Neoplasms; Oxazines; Platinum; Rhodamines

2020
Anticancer Melatplatin Prodrugs: High Effect and Low Toxicity, MT1-ER-Target and Immune Response
    Journal of medicinal chemistry, 2020, 06-11, Volume: 63, Issue:11

    Topics: Animals; Antineoplastic Agents; Apoptosis; Binding Sites; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; DNA Damage; Humans; Immune System; Mice; Mice, Nude; Molecular Docking Simulation; Neoplasms; NF-kappa B; Platinum; Prodrugs; Protein Structure, Tertiary; Receptor, Melatonin, MT1; Receptors, Estrogen

2020
Platinum-carbon-integrated nanozymes for enhanced tumor photodynamic and photothermal therapy.
    Nanoscale, 2020, Jul-02, Volume: 12, Issue:25

    Topics: Carbon; Humans; Neoplasms; Photochemotherapy; Photothermal Therapy; Platinum

2020
CAIXplatins: Highly Potent Platinum(IV) Prodrugs Selective Against Carbonic Anhydrase IX for the Treatment of Hypoxic Tumors.
    Angewandte Chemie (International ed. in English), 2020, 10-12, Volume: 59, Issue:42

    Topics: Animals; Carbonic Anhydrase IX; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cisplatin; Cluster Analysis; Coordination Complexes; Drug Screening Assays, Antitumor; Humans; Larva; Mice; Mice, Nude; Neoplasms; Platinum; Prodrugs; Proteome; Proteomics; Zebrafish

2020
Biotinylated platinum(ii) metallacage towards targeted cancer theranostics.
    Chemical communications (Cambridge, England), 2020, Jul-28, Volume: 56, Issue:60

    Topics: Biotin; Cell Line, Tumor; Cell Survival; Coordination Complexes; Fluorescent Dyes; Humans; Microscopy, Confocal; Neoplasms; Platinum; Theranostic Nanomedicine

2020
Oxygen Vacancy Defect-Induced Activity Enhancement of Gd Doping Magnetic Nanocluster for Oxygen Supplying Cancer Theranostics.
    ACS applied materials & interfaces, 2020, Aug-19, Volume: 12, Issue:33

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Contrast Media; Gadolinium; Humans; Magnetic Resonance Imaging; Magnetite Nanoparticles; Neoplasms; Oxygen; Platinum; Prodrugs; Reactive Oxygen Species; Surface Properties; Theranostic Nanomedicine

2020
Dual-Emissive Platinum(II) Metallacage with a Sensitive Oxygen Response for Imaging of Hypoxia and Imaging-Guided Chemotherapy.
    Angewandte Chemie (International ed. in English), 2020, 11-02, Volume: 59, Issue:45

    Topics: Antineoplastic Agents; Cell Hypoxia; Fluorescence Resonance Energy Transfer; Humans; Neoplasms; Oxygen; Platinum; Precision Medicine; Spectrophotometry, Ultraviolet

2020
Ultrasmall Peptide-Coated Platinum Nanoparticles for Precise NIR-II Photothermal Therapy by Mitochondrial Targeting.
    ACS applied materials & interfaces, 2020, Sep-02, Volume: 12, Issue:35

    Topics: Animals; Carbocyanines; Cell Survival; Hep G2 Cells; Humans; Infrared Rays; Metal Nanoparticles; Mice; Mice, Nude; Microscopy, Confocal; Mitochondria; Neoplasms; Peptides; Photothermal Therapy; Platinum; Transplantation, Heterologous

2020
Enhanced cellular uptake of platinum by a tetracationic Pt(II) nanocapsule and its implications to cancer treatment.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2020, Dec-01, Volume: 155

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Humans; Nanocapsules; Neoplasms; Platinum

2020
Near Infrared-Activatable Platinum-Decorated Gold Nanostars for Synergistic Photothermal/Ferroptotic Therapy in Combating Cancer Drug Resistance.
    Advanced healthcare materials, 2020, Volume: 9, Issue:20

    Topics: Cell Line, Tumor; Drug Resistance, Neoplasm; Ferroptosis; Gold; Neoplasms; Platinum

2020
Soft salts based on platinum(II) complexes with high emission quantum efficiencies in the near infrared region for
    Chemical communications (Cambridge, England), 2020, Oct-01, Volume: 56, Issue:78

    Topics: Animals; Anions; Cations; Coordination Complexes; HeLa Cells; Humans; Mice; Mice, Nude; Molecular Conformation; Neoplasms; Optical Imaging; Platinum; Quantum Theory; Static Electricity; Transplantation, Heterologous

2020
Macrocyclic NHC complexes of group 10 elements with enlarged aromaticity for biological studies.
    Dalton transactions (Cambridge, England : 2003), 2020, Oct-20, Volume: 49, Issue:40

    Topics: Antineoplastic Agents; Apoptosis; Benzimidazoles; Cell Line, Tumor; Cisplatin; Coordination Complexes; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Fluorescent Dyes; Humans; Imidazoles; Ligands; Macrocyclic Compounds; Neoplasms; Nickel; Optical Imaging; Palladium; Platinum; Structure-Activity Relationship

2020
Nanoporous platinum needle for cancer tumor destruction by EChT and impedance-based intra-therapeutic monitoring.
    Nanoscale, 2020, Nov-12, Volume: 12, Issue:43

    Topics: Electric Impedance; Electric Stimulation Therapy; Electrochemistry; Electrodes; Humans; Nanopores; Neoplasms; Platinum

2020
Fluorogenic Pt complexes distinguish the quantity and folding behavior of RNA G-quadruplexes between live cancerous and healthy cells.
    Chemical communications (Cambridge, England), 2020, Nov-19, Volume: 56, Issue:92

    Topics: Animals; Biomarkers, Tumor; Biosensing Techniques; Cattle; CHO Cells; Coordination Complexes; Cricetulus; DNA; Fluorescent Dyes; G-Quadruplexes; HeLa Cells; Humans; Kinetics; Liver; Molecular Docking Simulation; Neoplasms; Nucleic Acid Conformation; Optical Imaging; Platinum; RNA

2020
Pd@Pt-GOx/HA as a Novel Enzymatic Cascade Nanoreactor for High-Efficiency Starving-Enhanced Chemodynamic Cancer Therapy.
    ACS applied materials & interfaces, 2020, Nov-18, Volume: 12, Issue:46

    Topics: Animals; Apoptosis; Biocatalysis; Biocompatible Materials; Cell Line, Tumor; Glucose; Glucose Oxidase; Hyaluronic Acid; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Nanostructures; Neoplasms; Oxygen; Palladium; Platinum; Reactive Oxygen Species; Tissue Distribution; Transplantation, Homologous

2020
An Efficient Conjugation Approach for Coupling Drugs to Native Antibodies via the Pt
    Angewandte Chemie (International ed. in English), 2021, 02-08, Volume: 60, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Cell Line, Tumor; Coordination Complexes; Deferoxamine; Humans; Immunoconjugates; Mice; Neoplasms; Platinum; Receptor, ErbB-2; Sodium Iodide; Tissue Distribution; Transplantation, Heterologous; Trastuzumab

2021
Core-shell FePt-cube@covalent organic polymer nanocomposites: a multifunctional nanocatalytic agent for primary and metastatic tumor treatment.
    Journal of materials chemistry. B, 2020, 12-23, Volume: 8, Issue:48

    Topics: Animals; Antineoplastic Agents; Catalysis; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Ferric Compounds; Humans; MCF-7 Cells; Mice; Nanocomposites; Neoplasms; Photothermal Therapy; Platinum; Polymers; Tumor Microenvironment; Xenograft Model Antitumor Assays

2020
Combined chemotherapy of platinum and fluorouracil promotes T cell-mediated antitumor immunity.
    Acta biochimica et biophysica Sinica, 2021, Jan-12, Volume: 53, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Disease Models, Animal; Drug Therapy, Combination; Fluorouracil; Humans; Melanoma; Mice, Inbred C57BL; Neoplasms; NF-kappa B p50 Subunit; Oxaliplatin; Platinum; Stomach Neoplasms; T-Lymphocyte Subsets; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Helper-Inducer

2021
Carrier-Free Platinum Nanomedicine for Targeted Cancer Therapy.
    Small (Weinheim an der Bergstrasse, Germany), 2020, Volume: 16, Issue:49

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Delivery Systems; Drug Liberation; Humans; Nanomedicine; Nanoparticles; Neoplasms; Platinum

2020
GDF-15 Neutralization Alleviates Platinum-Based Chemotherapy-Induced Emesis, Anorexia, and Weight Loss in Mice and Nonhuman Primates.
    Cell metabolism, 2020, 12-01, Volume: 32, Issue:6

    Topics: Animals; Anorexia; Antineoplastic Agents; Female; Growth Differentiation Factor 15; Humans; Macaca fascicularis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, SCID; Neoplasms; Platinum; Vomiting; Weight Loss

2020
Pt@polydopamine nanoparticles as nanozymes for enhanced photodynamic and photothermal therapy.
    Chemical communications (Cambridge, England), 2021, Jan-07, Volume: 57, Issue:2

    Topics: Animals; Cell Line, Tumor; Humans; Indoles; Infrared Rays; Mice; Mice, Nude; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Photothermal Therapy; Platinum; Polymers; Xenograft Model Antitumor Assays

2021
Implantable Cisplatin Synthesis Microdevice for Regional Chemotherapy.
    Advanced healthcare materials, 2021, Volume: 10, Issue:3

    Topics: Animals; Antineoplastic Agents; Cisplatin; Drug Delivery Systems; Mice; Neoplasms; Platinum

2021
Self-Assembled Platinum Supramolecular Metallacycles Based on a Novel TADF Photosensitizer for Efficient Cancer Photochemotherapy.
    Molecular pharmaceutics, 2021, 03-01, Volume: 18, Issue:3

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Fluorescence; HeLa Cells; Humans; Mitochondria; Neoplasms; Photochemotherapy; Photosensitizing Agents; Platinum

2021
Au-Pt Nanoparticle Formulation as a Radiosensitizer for Radiotherapy with Dual Effects.
    International journal of nanomedicine, 2021, Volume: 16

    Topics: Animals; Catalysis; Cell Line, Tumor; Cell Survival; Female; Gold; Human Umbilical Vein Endothelial Cells; Humans; Metal Nanoparticles; Mice; Mice, Inbred BALB C; Neoplasms; Platinum; Radiation-Sensitizing Agents; Tissue Distribution; Tumor Microenvironment

2021
Fluorescent palladium(II) and platinum(II) NHC/1,2,3-triazole complexes: antiproliferative activity and selectivity against cancer cells.
    Dalton transactions (Cambridge, England : 2003), 2021, Feb-16, Volume: 50, Issue:6

    Topics: Antineoplastic Agents; Cell Line; Cell Proliferation; Cell Survival; Coordination Complexes; Coumarins; Fluorescence; Humans; Microscopy, Fluorescence; Neoplasms; Organometallic Compounds; Palladium; Platinum; Triazoles

2021
Evaluation of Efficacy and Safety of Nab-Paclitaxel vs Paclitaxel in Platinum-Refractory Metastatic Urothelial Cancer-Reply.
    JAMA oncology, 2021, 04-01, Volume: 7, Issue:4

    Topics: Albumins; Humans; Neoplasms; Paclitaxel; Platinum

2021
A Versatile Fluorescent Sensor Array for Platinum Anticancer Drug Detection in Biological Fluids.
    ACS sensors, 2021, 03-26, Volume: 6, Issue:3

    Topics: Antineoplastic Agents; Cisplatin; Humans; Neoplasms; Platinum

2021
Association of Urine Platinum With Acute Kidney Injury in Children Treated With Cisplatin for Cancer.
    Journal of clinical pharmacology, 2021, Volume: 61, Issue:7

    Topics: Acute Kidney Injury; Antineoplastic Agents; Biomarkers; Child; Child, Preschool; Cisplatin; Dose-Response Relationship, Drug; Electrolytes; Female; Hepatitis A Virus Cellular Receptor 1; Humans; Kidney Function Tests; Lipocalin-2; Male; Neoplasms; Platinum

2021
Rapid Capture and Photocatalytic Inactivation of Target Cells from Whole Blood by Rotating Janus Nanotubes.
    ACS applied materials & interfaces, 2021, Mar-24, Volume: 13, Issue:11

    Topics: Catalysis; Cell Line, Tumor; Cell Separation; Human Umbilical Vein Endothelial Cells; Humans; Magnetic Iron Oxide Nanoparticles; Metal Nanoparticles; Nanotubes; Neoplasms; Neoplastic Cells, Circulating; Photochemical Processes; Platinum; Titanium

2021
Platinum-Doped Prussian Blue Nanozymes for Multiwavelength Bioimaging Guided Photothermal Therapy of Tumor and Anti-Inflammation.
    ACS nano, 2021, 03-23, Volume: 15, Issue:3

    Topics: Ferrocyanides; Humans; Neoplasms; Phototherapy; Photothermal Therapy; Platinum

2021
Overcoming Radiation Resistance by Iron-Platinum Metal Alloy Nanoparticles in Human Copper Transport 1-Overexpressing Cancer Cells via Mitochondrial Disturbance.
    International journal of nanomedicine, 2021, Volume: 16

    Topics: Aerobiosis; Alloys; Animals; Cell Line, Tumor; Cell Respiration; Copper Transporter 1; Glutathione; Humans; Iron; Metal Nanoparticles; Mice, SCID; Mitochondria; Models, Biological; Neoplasms; Platinum; Radiation Tolerance; Reactive Oxygen Species; Treatment Outcome; X-Rays

2021
Effect of the aniline fragment in Pt(II) and Pt(IV) complexes as anti-proliferative agents. Standard reduction potential as a more reliable parameter for Pt(IV) compounds than peak reduction potential.
    Journal of inorganic biochemistry, 2021, Volume: 218

    Topics: A549 Cells; Aniline Compounds; Antineoplastic Agents; Apoptosis; Cell Proliferation; HCT116 Cells; Humans; MCF-7 Cells; Neoplasms; Organoplatinum Compounds; Platinum; Prodrugs

2021
Toll-like receptor 4 is activated by platinum and contributes to cisplatin-induced ototoxicity.
    EMBO reports, 2021, 05-05, Volume: 22, Issue:5

    Topics: Antineoplastic Agents; Cisplatin; Humans; Neoplasms; Ototoxicity; Platinum; Toll-Like Receptor 4

2021
Magneto-Electrically Enhanced Intracellular Catalysis of FePt-FeC Heterostructures for Chemodynamic Therapy.
    Advanced materials (Deerfield Beach, Fla.), 2021, Volume: 33, Issue:17

    Topics: Catalysis; Hydrogen Peroxide; Intracellular Space; Iron; Magnetic Phenomena; Nanoparticles; Neoplasms; Platinum

2021
3D CoPt nanostructures hybridized with iridium complexes for multimodal imaging and combined photothermal-chemotherapy.
    Journal of inorganic biochemistry, 2021, Volume: 219

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cobalt; Combined Modality Therapy; Coordination Complexes; Drug Delivery Systems; Drug Therapy, Combination; Humans; Iridium; Mice; Multimodal Imaging; Nanoparticles; Neoplasms; Photoacoustic Techniques; Photothermal Therapy; Platinum; Povidone; Theranostic Nanomedicine

2021
    Journal of applied social psychology, 2021, Volume: 51, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Antigens, Surface; Antineoplastic Agents; Antioxidants; Antiviral Agents; Aporphines; Atherosclerosis; Benzoyl Peroxide; beta Catenin; Biofilms; Biomarkers; Brain; Cannabis; Carcinoma, Squamous Cell; Case-Control Studies; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Child; China; Chlorides; Chlorophyll; Cholesterol, LDL; Coinfection; Corylus; Cross-Sectional Studies; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Developmental Disabilities; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Electroencephalography; Environmental Exposure; Enzyme Inhibitors; Epilepsy, Generalized; Ethnicity; Female; Fertilization in Vitro; Fluorescent Dyes; Follow-Up Studies; Forecasting; Glutamate Carboxypeptidase II; Glycine; Half-Life; Head and Neck Neoplasms; Health Communication; Heart Ventricles; Hepacivirus; Hepatitis C; Heterosexuality; HIV Infections; Humans; Hypercholesterolemia; Immunoassay; Inhalation Exposure; Isocitrate Dehydrogenase; Laryngeal Neoplasms; Ligands; Light; Lipopolysaccharide Receptors; Liver Cirrhosis; Lung; Lung Neoplasms; Magnetic Resonance Imaging, Cine; Male; Maternal Age; Mechanical Phenomena; Mice; Mice, Nude; Mice, SCID; Microglia; MicroRNAs; Microscopy, Fluorescence; Microsomes, Liver; Middle Aged; Minority Groups; Mitochondrial Membrane Transport Proteins; Models, Biological; Molecular Structure; Molecular Weight; Monte Carlo Method; Muscle Hypotonia; Mutagenesis, Site-Directed; Mutation, Missense; Natriuretic Peptide, Brain; Neoplasms; Nickel; Nitric Oxide; Optical Imaging; Oxides; Particle Size; Particulate Matter; PCSK9 Inhibitors; Peptide Fragments; Phenotype; Photochemotherapy; Photosensitizing Agents; Phytochemicals; Piper; Placenta Growth Factor; Plant Extracts; Plant Leaves; Plant Stems; Platinum; Point-of-Care Testing; Population Surveillance; Postpartum Period; Pregnancy; Pregnancy, Twin; Prevalence; Prospective Studies; Prostatic Neoplasms; Pseudomonas aeruginosa; Pyridines; Pyridones; Racial Groups; Rats; Respiratory Physiological Phenomena; Retrospective Studies; Risk Factors; RNA, Long Noncoding; Semiconductors; Sexual and Gender Minorities; Sexual Behavior; Social Media; Sodium; Solubility; Stereoisomerism; Stochastic Processes; Structure-Activity Relationship; Substance-Related Disorders; Sustained Virologic Response; Sweat; Temperature; Time Factors; Tissue Distribution; Titanium; Transplantation, Heterologous; Tumor Cells, Cultured; Tungsten; Tyramine; United States; Up-Regulation; Ventricular Dysfunction, Left; Ventricular Function, Left; Veterans; Xenograft Model Antitumor Assays; Young Adult

2021
Complementary atomic flame/molecular colorimetry dual-mode assay for sensitive and wide-range detection of cancer cells.
    Chemical communications (Cambridge, England), 2021, Apr-07, Volume: 57, Issue:27

    Topics: Colorimetry; Humans; Hydrogen Peroxide; Nanoparticles; Neoplasms; Platinum; Strontium

2021
Erythrocyte Membrane-Camouflaged PCN-224 Nanocarriers Integrated with Platinum Nanoparticles and Glucose Oxidase for Enhanced Tumor Sonodynamic Therapy and Synergistic Starvation Therapy.
    ACS applied materials & interfaces, 2021, Jun-02, Volume: 13, Issue:21

    Topics: Animals; Combined Modality Therapy; Drug Carriers; Erythrocyte Membrane; Glucose Oxidase; Metal Nanoparticles; Mice; Mice, Inbred ICR; Neoplasms; Platinum; Tumor Hypoxia; Ultrasonic Therapy; Xenograft Model Antitumor Assays

2021
Supramolecular Polymerization-Induced Nanoassemblies for Self-Augmented Cascade Chemotherapy and Chemodynamic Therapy of Tumor.
    Angewandte Chemie (International ed. in English), 2021, 08-02, Volume: 60, Issue:32

    Topics: Animals; Antineoplastic Agents; beta-Cyclodextrins; Cell Line, Tumor; Coordination Complexes; Drug Carriers; Drug Liberation; Female; Ferrous Compounds; Hydrogen Peroxide; Hydroxyl Radical; Metallocenes; Mice, Inbred BALB C; Nanomedicine; Nanoparticles; Neoplasms; Platinum; Polymerization; Polymers; Prodrugs

2021
Red-light-responsive coordination polymers nanorods: New strategy for ultrasensitive photothermal detection of targeted cancer cells.
    Biosensors & bioelectronics, 2021, Oct-15, Volume: 190

    Topics: Biosensing Techniques; Folic Acid; Nanotubes; Neoplasms; Platinum; Polymers

2021
Shuttle-Shape Carrier-Free Platinum-Coordinated Nanoreactors with O
    ACS applied materials & interfaces, 2021, Jul-21, Volume: 13, Issue:28

    Topics: Animals; Antineoplastic Agents; Camptothecin; Catalysis; Cell Line, Tumor; Drug Carriers; Drug Liberation; Female; Humans; Hydrogen Peroxide; Light; Methylene Blue; Mice, Inbred BALB C; Nanostructures; Neoplasms; Oxygen; Photosensitizing Agents; Photothermal Therapy; Platinum; Polymers; Porosity; Singlet Oxygen; Theranostic Nanomedicine; Tumor Hypoxia

2021
Fe
    Journal of nanobiotechnology, 2021, Jul-10, Volume: 19, Issue:1

    Topics: Animals; Antineoplastic Agents; Catalysis; Cell Line, Tumor; Cell Survival; Combined Modality Therapy; Female; Ferric Compounds; Glutathione; Hydrogen Peroxide; Kinetics; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasms; Platinum; Reactive Oxygen Species; Tumor Microenvironment

2021
Ultrathin Two-Dimensional Plasmonic PtAg Nanosheets for Broadband Phototheranostics in Both NIR-I and NIR-II Biowindows.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021, Volume: 8, Issue:17

    Topics: Animals; Biosensing Techniques; Cell Line, Tumor; Disease Models, Animal; Infrared Rays; Mice; Nanoparticles; Neoplasms; Photoacoustic Techniques; Photothermal Therapy; Platinum; Silver; Theranostic Nanomedicine

2021
Early phago-/endosomal escape of platinum drugs via ROS-responsive micelles for dual cancer chemo/immunotherapy.
    Biomaterials, 2021, Volume: 276

    Topics: Cell Line, Tumor; Immunotherapy; Micelles; Neoplasms; Platinum; Reactive Oxygen Species

2021
A Robust Narrow Bandgap Vanadium Tetrasulfide Sonosensitizer Optimized by Charge Separation Engineering for Enhanced Sonodynamic Cancer Therapy.
    Advanced materials (Deerfield Beach, Fla.), 2021, Volume: 33, Issue:36

    Topics: Animals; Catalysis; Cell Line, Tumor; Free Radicals; Glutathione; Humans; Metal Nanoparticles; Mice; Neoplasms; Oxidative Stress; Platinum; Reactive Oxygen Species; Signal Transduction; Sulfides; Tumor Hypoxia; Tumor Microenvironment; Ultrasonic Therapy; Vanadium Compounds

2021
The design and fabrication of nanoengineered platinum needles with laser welded carbon nanotubes (CNTs) for the electrochemical biosensing of cancer lymph nodes.
    Biomaterials science, 2021, Sep-14, Volume: 9, Issue:18

    Topics: Animals; Biosensing Techniques; Electrochemical Techniques; Electrodes; Lasers; Lymph Nodes; Nanotubes, Carbon; Needles; Neoplasms; Platinum; Rabbits

2021
Recent Progresses in Conjugation with Bioactive Ligands to Improve the Anticancer Activity of Platinum Compounds.
    Current medicinal chemistry, 2022, Volume: 29, Issue:15

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Cisplatin; Humans; Ligands; Neoplasms; Platinum; Platinum Compounds; Radiation-Sensitizing Agents

2022
Structure-Activity Relationships of Triple-Action Platinum(IV) Prodrugs with Albumin-Binding Properties and Immunomodulating Ligands.
    Journal of medicinal chemistry, 2021, 08-26, Volume: 64, Issue:16

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Coordination Complexes; Drug Screening Assays, Antitumor; Female; Humans; Immunologic Factors; Indoleamine-Pyrrole 2,3,-Dioxygenase; Male; Maleimides; Mice, Inbred BALB C; Mice, SCID; Molecular Structure; Neoplasms; Platinum; Prodrugs; Structure-Activity Relationship; Succinimides

2021
Electrokinetic device design and constraints for use in high conductance solutions.
    Electrophoresis, 2017, Volume: 38, Issue:11

    Topics: Animals; Antibodies, Monoclonal; Biomarkers; Computer Simulation; DNA; Electric Conductivity; Equipment Design; Exosomes; Fluorescent Dyes; Humans; Kinetics; Lab-On-A-Chip Devices; Mice; Microelectrodes; Models, Theoretical; Neoplasms; Platinum; Polytetrafluoroethylene; Solutions

2017
Platinum covalent shell cross-linked micelles designed to deliver doxorubicin for synergistic combination cancer therapy.
    International journal of nanomedicine, 2017, Volume: 12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Death; Cross-Linking Reagents; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Liberation; HeLa Cells; Humans; Micelles; Microscopy, Electron, Transmission; Nanoparticles; Neoplasms; Platinum; Polymers; Prodrugs; Spectroscopy, Fourier Transform Infrared

2017
Platinum(IV) complexes conjugated with phenstatin analogue as inhibitors of microtubule polymerization and reverser of multidrug resistance.
    Bioorganic & medicinal chemistry, 2017, 09-01, Volume: 25, Issue:17

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzophenones; Binding Sites; Cell Line, Tumor; Cisplatin; Coordination Complexes; Drug Design; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; G2 Phase Cell Cycle Checkpoints; Humans; M Phase Cell Cycle Checkpoints; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Molecular Dynamics Simulation; Neoplasms; Platinum; Protein Structure, Tertiary; Rats; Reactive Oxygen Species; Transplantation, Heterologous; Tubulin; Tubulin Modulators

2017
Platinum Binds Proteins in the Endoplasmic Reticulum of S. cerevisiae and Induces Endoplasmic Reticulum Stress.
    ACS chemical biology, 2017, 11-17, Volume: 12, Issue:11

    Topics: Antineoplastic Agents; Endoplasmic Reticulum Stress; Humans; Neoplasms; Platinum; Protein Binding; Proteomics; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2017
Biotinylated platinum(IV) complexes designed to target cancer cells.
    Journal of inorganic biochemistry, 2017, Volume: 176

    Topics: Antineoplastic Agents; Biotin; Biotinylation; Coordination Complexes; Drug Delivery Systems; Hep G2 Cells; Humans; MCF-7 Cells; Molecular Docking Simulation; Neoplasms; Platinum

2017
Au@Pt nanoparticles as catalase mimics to attenuate tumor hypoxia and enhance immune cell-mediated cytotoxicity.
    Nanotechnology, 2017, Nov-17, Volume: 28, Issue:46

    Topics: Biomimetic Materials; Catalase; Cell Hypoxia; Cell Line, Tumor; Gold; Humans; Immunity, Cellular; Immunotherapy; Metal Nanoparticles; Neoplasms; Platinum

2017
Mitochondrial-targeted multifunctional mesoporous Au@Pt nanoparticles for dual-mode photodynamic and photothermal therapy of cancers.
    Nanoscale, 2017, Oct-26, Volume: 9, Issue:41

    Topics: A549 Cells; Gold; Hot Temperature; Humans; MCF-7 Cells; Metal Nanoparticles; Mitochondria; Neoplasms; Photochemotherapy; Photosensitizing Agents; Platinum; Reactive Oxygen Species

2017
A biomimetic theranostic O
    Biomaterials, 2018, Volume: 151

    Topics: Animals; Antineoplastic Agents; Biological Transport; Biomimetics; Cell Line, Tumor; Coordination Complexes; Fluorescence; Haplorhini; Humans; Light; Metal-Organic Frameworks; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasms; Optical Imaging; Oxygen; Particle Size; Photochemotherapy; Photosensitizing Agents; Platinum; Porphyrins; Surface Properties; Theranostic Nanomedicine

2018
Albumin-coordinated assembly of clearable platinum nanodots for photo-induced cancer theranostics.
    Biomaterials, 2018, Volume: 154

    Topics: Albumins; Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Proliferation; Endocytosis; Fluorescence; Humans; Kinetics; Mice, Inbred BALB C; Mice, Nude; Multimodal Imaging; Nanostructures; Neoplasms; Photoacoustic Techniques; Phototherapy; Platinum; Theranostic Nanomedicine; Tissue Distribution; Tomography, X-Ray Computed

2018
Porous Au@Pt Nanoparticles: Therapeutic Platform for Tumor Chemo-Photothermal Co-Therapy and Alleviating Doxorubicin-Induced Oxidative Damage.
    ACS applied materials & interfaces, 2018, Jan-10, Volume: 10, Issue:1

    Topics: Cell Line, Tumor; Doxorubicin; Drug Delivery Systems; Gold; Humans; Metal Nanoparticles; Neoplasms; Oxidative Stress; Platinum; Porosity

2018
Nanozyme Decorated Metal-Organic Frameworks for Enhanced Photodynamic Therapy.
    ACS nano, 2018, 01-23, Volume: 12, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Catalase; Cell Line, Tumor; Female; HeLa Cells; Humans; Liver Neoplasms; Metal Nanoparticles; Metal-Organic Frameworks; Mice; Neoplasms; Photochemotherapy; Photosensitizing Agents; Platinum; Singlet Oxygen; Tumor Hypoxia

2018
Tobacco Mosaic Virus with Peroxidase-Like Activity for Cancer Cell Detection through Colorimetric Assay.
    Molecular pharmaceutics, 2018, 08-06, Volume: 15, Issue:8

    Topics: Biological Assay; Cell Line, Tumor; Chemistry, Pharmaceutical; Click Chemistry; Colorimetry; Enzyme-Linked Immunosorbent Assay; Humans; Metal Nanoparticles; Neoplasms; Peroxidases; Platinum; Tobacco Mosaic Virus

2018
Anticancer metallodrugs: where is the next cisplatin?
    Future medicinal chemistry, 2018, 03-01, Volume: 10, Issue:6

    Topics: Antineoplastic Agents; Cisplatin; Coordination Complexes; Endoplasmic Reticulum Stress; Humans; Neoplasms; Platinum; Prodrugs; Ruthenium

2018
Development of a carboplatin derivative conjugated with a collagen-like triple-helical peptide.
    Future medicinal chemistry, 2018, 03-01, Volume: 10, Issue:6

    Topics: Animals; Carboplatin; Cell Line, Tumor; Cell Survival; Cell-Penetrating Peptides; Collagen; Drug Design; Drug Stability; Half-Life; Humans; Male; Malonates; Mice; Mice, Inbred ICR; Neoplasms; Platinum; Prodrugs; Protein Structure, Secondary; Survival Rate; Transplantation, Heterologous

2018
One-Pot Facile Synthesis of Pt Nanoparticles Using Cultural Filtrate of Microgravity Simulated Grown
    Journal of nanoscience and nanotechnology, 2018, May-01, Volume: 18, Issue:5

    Topics: Bacteria; Bacterial Infections; Cell Survival; Metal Nanoparticles; Neoplasms; Platinum; Weightlessness

2018
Long term platinum-induced ototoxicity in pediatric patients.
    International journal of pediatric otorhinolaryngology, 2018, Volume: 107

    Topics: Adolescent; Antineoplastic Agents; Audiometry; Child; Child, Preschool; Cohort Studies; Disease Progression; Female; Hearing Loss; Humans; Incidence; Infant; Male; Neoplasms; Platinum; Prospective Studies; Surveys and Questionnaires

2018
Capturing platinum in cisplatin: kinetic reactions with recombinant human apo-metallothionein 1a.
    Metallomics : integrated biometal science, 2018, 05-23, Volume: 10, Issue:5

    Topics: Antineoplastic Agents; Apoproteins; Cisplatin; Humans; Kinetics; Metallothionein; Metals; Neoplasms; Platinum; Recombinant Proteins

2018
Platinum nanoparticles: a non-toxic, effective and thermally stable alternative plasmonic material for cancer therapy and bioengineering.
    Nanoscale, 2018, May-17, Volume: 10, Issue:19

    Topics: Cell Line, Tumor; Hot Temperature; Humans; Infrared Rays; Metal Nanoparticles; Neoplasms; Phototherapy; Platinum

2018
Oxygen and Pt(II) self-generating conjugate for synergistic photo-chemo therapy of hypoxic tumor.
    Nature communications, 2018, 05-24, Volume: 9, Issue:1

    Topics: Animals; Cell Line, Tumor; Chlorophyllides; Female; Humans; Hypoxia; Male; Mice; Mice, Nude; Nanoparticles; Neoplasms; Oxygen; Photochemotherapy; Photosensitizing Agents; Platinum; Porphyrins; Prodrugs; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2018
Multifunctional GQDs-Concanavalin A@Fe
    Analytica chimica acta, 2018, Oct-16, Volume: 1027

    Topics: Cell Survival; Concanavalin A; Doxorubicin; Drug Delivery Systems; Electrodes; Endothelial Cells; Ferrosoferric Oxide; Graphite; HeLa Cells; Humans; Limit of Detection; Nanocomposites; Neoplasms; Platinum; Quantum Dots

2018
Simulation of spatial diffusion of platinum from carboplatin-impregnated calcium sulfate hemihydrate beads by use of an agarose gelatin tissue phantom.
    American journal of veterinary research, 2018, Volume: 79, Issue:6

    Topics: Animals; Calcium Sulfate; Carboplatin; Dogs; Drug Screening Assays, Antitumor; Gelatin; Inhibitory Concentration 50; Mass Spectrometry; Microspheres; Neoplasms; Phantoms, Imaging; Platinum; Sepharose; Time Factors

2018
Uptake-release by MSCs of a cationic platinum(II) complex active in vitro on human malignant cancer cell lines.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 108

    Topics: Adipose Tissue; Adult; Antineoplastic Agents; Cations; Cell Cycle; Cell Line, Tumor; Cisplatin; Humans; Mesenchymal Stem Cells; Neoplasms; Neovascularization, Physiologic; Platinum; Temperature

2018
Shape-Controlled Synthesis of Luminescent Hemoglobin Capped Hollow Porous Platinum Nanoclusters and their Application to Catalytic Oxygen Reduction and Cancer Imaging.
    Scientific reports, 2018, 09-28, Volume: 8, Issue:1

    Topics: Catalysis; Cell Survival; Crystallization; Equipment Design; HeLa Cells; Hemoglobins; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Luminescence; Microscopy, Electron; Microscopy, Fluorescence; Nanostructures; Neoplasms; Oxidation-Reduction; Oxygen; Platinum; Porosity

2018
Integrating in situ formation of nanozymes with three-dimensional dendritic mesoporous silica nanospheres for hypoxia-overcoming photodynamic therapy.
    Nanoscale, 2018, Dec-13, Volume: 10, Issue:48

    Topics: A549 Cells; Chlorophyllides; Drug Delivery Systems; Humans; Metal Nanoparticles; Mitochondria; Nanospheres; Neoplasms; Photochemotherapy; Platinum; Porosity; Porphyrins; Silicon Dioxide; Tumor Hypoxia

2018
The interactions of novel mononuclear platinum-based complexes with DNA.
    BMC cancer, 2018, Dec-22, Volume: 18, Issue:1

    Topics: Cisplatin; Cross-Linking Reagents; DNA; DNA Adducts; DNA Damage; HeLa Cells; Humans; Neoplasms; Nucleic Acid Conformation; Organoplatinum Compounds; Platinum; Stereoisomerism

2018
A photoacoustic shockwave triggers the size shrinkage of nanoparticles to obviously improve tumor penetration and therapeutic efficacy.
    Nanoscale, 2019, Jan-17, Volume: 11, Issue:3

    Topics: Animals; Apoptosis; Carbocyanines; Cell Line, Tumor; Coordination Complexes; Dendrimers; Fluorocarbons; Humans; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Microwaves; Nanoparticles; Neoplasms; Photoacoustic Techniques; Platinum; Prodrugs; Tissue Distribution; Transplantation, Heterologous

2019
Porous platinum nanoparticles as a high-Z and oxygen generating nanozyme for enhanced radiotherapy in vivo.
    Biomaterials, 2019, Volume: 197

    Topics: Animals; Cell Line, Tumor; Humans; Hydrogen Peroxide; Male; Metal Nanoparticles; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Oxygen; Platinum; Porosity

2019
Emerging platinum(iv) prodrugs to combat cisplatin resistance: from isolated cancer cells to tumor microenvironment.
    Dalton transactions (Cambridge, England : 2003), 2019, Feb-19, Volume: 48, Issue:8

    Topics: Antineoplastic Agents; Cell Hypoxia; Cisplatin; Coordination Complexes; Drug Carriers; Drug Resistance, Neoplasm; Humans; Nanoparticles; Neoplasms; Platinum; Prodrugs; Tumor Microenvironment

2019
Tetrathiomolybdate induces dimerization of the metal-binding domain of ATPase and inhibits platination of the protein.
    Nature communications, 2019, 01-14, Volume: 10, Issue:1

    Topics: Antineoplastic Agents; Chelating Agents; Cisplatin; Copper; Copper-Transporting ATPases; Cross-Linking Reagents; Crystallography, X-Ray; Cysteine; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Inhibitors; Humans; Molybdenum; Neoplasms; Platinum; Protein Interaction Domains and Motifs; Protein Multimerization; Protein Structure, Secondary

2019
One-pot synthesized Cu/Au/Pt trimetallic nanoparticles with enhanced catalytic and plasmonic properties as a universal platform for biosensing and cancer theranostics.
    Chemical communications (Cambridge, England), 2019, Feb-19, Volume: 55, Issue:16

    Topics: Aptamers, Nucleotide; Biosensing Techniques; Catalysis; Cell Line, Tumor; Copper; Glucose; Gold; Humans; Metal Nanoparticles; Neoplasms; Platinum; Theranostic Nanomedicine

2019
A comparison of the Muenster, SIOP Boston, Brock, Chang and CTCAEv4.03 ototoxicity grading scales applied to 3,799 audiograms of childhood cancer patients treated with platinum-based chemotherapy.
    PloS one, 2019, Volume: 14, Issue:2

    Topics: Antineoplastic Agents; Audiometry; Carboplatin; Child; Cisplatin; Female; Hearing Loss; Humans; Male; Neoplasms; Platinum

2019
Synthesis, Spectroscopic Properties, Crystal Structure And Biological Evaluation of New Platinum Complexes with 5-methyl-5-(2-thiomethyl)ethyl Hydantoin.
    Anti-cancer agents in medicinal chemistry, 2019, Volume: 19, Issue:10

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Coordination Complexes; Female; Humans; Hydantoins; Mice; Molecular Conformation; Neoplasms; Platinum

2019
Age-related differences in patient-reported and objective measures of chemotherapy-induced peripheral neuropathy among cancer survivors.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019, Volume: 27, Issue:10

    Topics: Aged; Antineoplastic Agents; Bridged-Ring Compounds; Cancer Survivors; Female; Humans; Induction Chemotherapy; Male; Middle Aged; Neoplasms; Pain; Patient Reported Outcome Measures; Peripheral Nervous System Diseases; Platinum; Self Report; Surveys and Questionnaires; Taxoids

2019
New Platinum(IV) and Palladium(II) Transition Metal Complexes of s-Triazine Derivative: Synthesis, Spectral, and Anticancer Agents Studies.
    BioMed research international, 2019, Volume: 2019

    Topics: Anti-Infective Agents; Antineoplastic Agents; Aspergillus flavus; Candida albicans; Cell Line, Tumor; Coordination Complexes; Escherichia coli; Humans; Neoplasms; Palladium; Platinum; Staphylococcus aureus; Triazines

2019
Recoverable Bismuth-Based Microrobots: Capture, Transport, and On-Demand Release of Heavy Metals and an Anticancer Drug in Confined Spaces.
    ACS applied materials & interfaces, 2019, Apr-10, Volume: 11, Issue:14

    Topics: Antineoplastic Agents; Bismuth; Chromium; Confined Spaces; Doxorubicin; Drug Liberation; Humans; Metals, Heavy; Nanotechnology; Neoplasms; Platinum

2019
Polynuclear ruthenium organometallic compounds induce DNA damage in human cells identified by the nucleotide excision repair factor XPC.
    Bioscience reports, 2019, 07-31, Volume: 39, Issue:7

    Topics: Cell Line, Tumor; Cell Proliferation; Chromatin; DNA Damage; DNA Repair; DNA-Binding Proteins; Humans; Neoplasms; Organometallic Compounds; Platinum; Ruthenium

2019
Glyconanoparticles for Targeted Tumor Therapy of Platinum Anticancer Drug.
    Biomacromolecules, 2019, 08-12, Volume: 20, Issue:8

    Topics: Antineoplastic Agents; Cell Proliferation; Drug Carriers; Drug Delivery Systems; Glycosides; Humans; Nanoparticles; Neoplasms; Platinum; Polymers; Tumor Cells, Cultured

2019
Nanozymes-Engineered Metal-Organic Frameworks for Catalytic Cascades-Enhanced Synergistic Cancer Therapy.
    Nano letters, 2019, 08-14, Volume: 19, Issue:8

    Topics: Animals; Cell Line, Tumor; Gold; Humans; Metal Nanoparticles; Metal-Organic Frameworks; Mice; Neoplasms; Photochemotherapy; Platinum; Porphyrins

2019
In vivo monitoring the process of tumor growth, metastasis and bacterial infection expressing GFP via real-time optical imaging.
    Journal of biomedical nanotechnology, 2013, Volume: 9, Issue:2

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Computer Systems; Escherichia coli Infections; Fluorescence; Green Fluorescent Proteins; Humans; Kanamycin; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Neoplasms; Optical Imaging; Peritoneal Neoplasms; Platinum; Rats; Subcutaneous Tissue

2013
Inductively coupled plasma mass-spectrometric determination of platinum in excretion products of client-owned pet dogs.
    Veterinary and comparative oncology, 2015, Volume: 13, Issue:2

    Topics: Animals; Antineoplastic Agents; Carboplatin; Cerumen; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Feces; Neoplasms; Platinum; Saliva; Sebum; Spectrophotometry, Atomic

2015
Transporting and shielding photosensitisers by using water-soluble organometallic cages: a new strategy in drug delivery and photodynamic therapy.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2013, Jun-24, Volume: 19, Issue:26

    Topics: Antineoplastic Agents; Apoptosis; Cisplatin; Coordination Complexes; Drug Carriers; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; Light; Neoplasms; Photochemotherapy; Photosensitizing Agents; Platinum; Ruthenium; Water

2013
Modulation of OATP1B-type transporter function alters cellular uptake and disposition of platinum chemotherapeutics.
    Molecular cancer therapeutics, 2013, Volume: 12, Issue:8

    Topics: Animals; Antineoplastic Agents; Biological Transport; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression; Humans; Liver-Specific Organic Anion Transporter 1; Male; Mice; Neoplasms; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Platinum; Solute Carrier Organic Anion Transporter Family Member 1B3

2013
cis-[Pt(II) (1R,2R-DACH)(3-acetoxy-1,1-cyclobutanedicarboxylato)], a water-soluble, oxalate-free and stable analogue of oxaliplatin: synthesis, characterization, and biological evaluations.
    ChemMedChem, 2013, Volume: 8, Issue:9

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Coordination Complexes; Crystallography, X-Ray; Cyclohexylamines; HT29 Cells; Humans; Isomerism; MCF-7 Cells; Molecular Conformation; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Platinum; Water

2013
Caged Pt nanoclusters exhibiting corrodibility to exert tumor-inside activation for anticancer chemotherapeutics.
    Advanced materials (Deerfield Beach, Fla.), 2013, Sep-25, Volume: 25, Issue:36

    Topics: Animals; Antineoplastic Agents; Carboplatin; Cell Line, Tumor; Cell Survival; Cisplatin; Dendrimers; Drug Carriers; Humans; Magnetic Resonance Imaging; Mice; Mice, Nude; Nanostructures; Neoplasms; Platinum; Radiography; Transplantation, Heterologous

2013
Internal heavy atom effect of Au(III) and Pt(IV) on hypocrellin A for enhanced in vitro photodynamic therapy of cancer.
    Bioorganic & medicinal chemistry letters, 2013, Oct-01, Volume: 23, Issue:19

    Topics: Cell Survival; Coordination Complexes; Gold; HeLa Cells; Humans; Metals, Heavy; Microscopy, Fluorescence; Models, Biological; Molecular Structure; Neoplasms; Perylene; Phenol; Photosensitizing Agents; Platinum; Quinones; Solubility; Spectroscopy, Fourier Transform Infrared

2013
Chemical and cellular investigations of trans-ammine-pyridine-dichlorido-platinum(II), the likely metabolite of the antitumor active cis-diammine-pyridine-chorido-platinum(II).
    Journal of inorganic biochemistry, 2013, Volume: 129

    Topics: Antineoplastic Agents; Cell Line, Tumor; DNA Adducts; DNA, Neoplasm; HMGB1 Protein; Humans; Neoplasm Proteins; Neoplasms; Platinum; Pyridines

2013
"Turn off-on" fluorescent sensor for platinum drugs-DNA interactions based on quantum dots.
    Biosensors & bioelectronics, 2014, Feb-15, Volume: 52

    Topics: Antineoplastic Agents; Biosensing Techniques; DNA; Fluorescence; Neoplasms; Platinum; Quantum Dots

2014
Robust structure and reactivity of aqueous arsenous acid-platinum(II) anticancer complexes.
    Angewandte Chemie (International ed. in English), 2013, Oct-04, Volume: 52, Issue:41

    Topics: Antineoplastic Agents; Arsenites; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Neoplasms; Organoplatinum Compounds; Platinum; Water

2013
Synthesis and in vitro pharmacological behavior of platinum(II) complexes containing 1,2-diamino-1-(4-fluorophenyl)-2-alkanol ligands.
    Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Drug Resistance, Neoplasm; Humans; Ligands; Models, Chemical; Molecular Structure; Neoplasms; Organoplatinum Compounds; Platinum; U937 Cells

2013
Combination studies of platinum(II)-based metallointercalators with buthionine-S,R-sulfoximine, 3-bromopyruvate, cisplatin or carboplatin.
    Metallomics : integrated biometal science, 2014, Volume: 6, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Carboplatin; Cell Line; Cell Line, Tumor; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Humans; Inhibitory Concentration 50; Molecular Structure; Neoplasms; Organoplatinum Compounds; Platinum; Pyruvates

2014
Imino-phosphine palladium(II) and platinum(II) complexes: synthesis, molecular structures and evaluation as antitumor agents.
    Journal of inorganic biochemistry, 2013, Volume: 129

    Topics: Antineoplastic Agents; Cell Line, Tumor; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Neoplasms; Palladium; Phosphines; Platinum

2013
Platinum porous nanoparticles hybrid with metal ions as probes for simultaneous detection of multiplex cancer biomarkers.
    Biosensors & bioelectronics, 2014, Mar-15, Volume: 53

    Topics: alpha-Fetoproteins; Antibodies; Biomarkers, Tumor; Biosensing Techniques; Enzyme-Linked Immunosorbent Assay; Gold; Graphite; Humans; Limit of Detection; Metal Nanoparticles; Neoplasms; Platinum

2014
In vivo multimodality imaging and cancer therapy by near-infrared light-triggered trans-platinum pro-drug-conjugated upconverison nanoparticles.
    Journal of the American Chemical Society, 2013, Dec-18, Volume: 135, Issue:50

    Topics: Humans; Magnetic Resonance Imaging; Microscopy, Electron, Transmission; Multimodal Imaging; Nanoparticles; Neoplasms; Platinum; Prodrugs; Spectrophotometry, Ultraviolet; Tomography, X-Ray Computed

2013
A single subexcitation-energy electron can induce a double-strand break in DNA modified by platinum chemotherapeutic drugs.
    ChemMedChem, 2014, Volume: 9, Issue:6

    Topics: Antineoplastic Agents; Coordination Complexes; DNA; DNA Breaks, Double-Stranded; Electrons; Humans; Neoplasms; Plasmids; Platinum; Radiation, Ionizing

2014
Guanidine platinum(II) complexes: synthesis, in vitro antitumor activity, and DNA interactions.
    Journal of inorganic biochemistry, 2014, Volume: 133

    Topics: Antineoplastic Agents; Cell Line, Tumor; DNA; Guanidine; Humans; Ligands; Molecular Structure; Neoplasms; Organoplatinum Compounds; Platinum; Stereoisomerism; Structure-Activity Relationship

2014
Platinum compounds for high-resolution in vivo cancer imaging.
    ChemMedChem, 2014, Volume: 9, Issue:6

    Topics: Animals; Antineoplastic Agents; Boron Compounds; Cell Line, Tumor; Coordination Complexes; DNA Damage; Fluorescent Antibody Technique; Fluorescent Dyes; Humans; Mice; Mice, Nude; Neoplasms; Platinum; Radiography; Transplantation, Heterologous

2014
Au@Pt nanostructures: a novel photothermal conversion agent for cancer therapy.
    Nanoscale, 2014, Apr-07, Volume: 6, Issue:7

    Topics: Animals; Cell Line, Tumor; Cell Survival; Gold; Humans; Lasers; Low-Level Light Therapy; Mice; Mice, Inbred BALB C; Mice, Nude; Nanostructures; Nanotubes; Neoplasms; Platinum; Surface Plasmon Resonance; Temperature; Transplantation, Heterologous

2014
Platinum porous nanoparticles for the detection of cancer biomarkers: what are the advantages over existing techniques?
    Bioanalysis, 2014, Volume: 6, Issue:7

    Topics: Biomarkers, Tumor; Electrochemical Techniques; Enzyme-Linked Immunosorbent Assay; Humans; Metal Nanoparticles; Neoplasms; Platinum

2014
Raman spectroscopic evaluation of DNA adducts of a platinum containing anticancer drug.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014, Sep-15, Volume: 130

    Topics: Adenine; Animals; Antineoplastic Agents; Carboplatin; Cattle; Cisplatin; Cross-Linking Reagents; DNA; DNA Adducts; Guanine; Humans; Neoplasms; Nucleic Acid Conformation; Platinum; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Thymus Gland

2014
Selenium-platinum coordination compounds as novel anticancer drugs: selectively killing cancer cells via a reactive oxygen species (ROS)-mediated apoptosis route.
    Chemistry, an Asian journal, 2014, Volume: 9, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Humans; Neoplasms; Platinum; Reactive Oxygen Species; Selenium; Spectrum Analysis

2014
Novel combination of mitochondrial division inhibitor 1 (mdivi-1) and platinum agents produces synergistic pro-apoptotic effect in drug resistant tumor cells.
    Oncotarget, 2014, Jun-30, Volume: 5, Issue:12

    Topics: Apoptosis; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Drug Synergism; Humans; Mitochondrial Dynamics; Neoplasms; Platinum; Quinazolinones

2014
Biological properties of benzopyran-based platinum (II) complexes.
    Polski przeglad chirurgiczny, 2014, Volume: 86, Issue:4

    Topics: Adult; Aged; Antioxidants; Benzopyrans; Catalase; Female; Glutathione; Glutathione Peroxidase; Healthy Volunteers; Humans; Lipid Peroxidation; Male; Middle Aged; Neoplasms; Platinum; Poland; Reactive Oxygen Species; Superoxide Dismutase

2014
Integration of platinum nanoparticles with a volumetric bar-chart chip for biomarker assays.
    Angewandte Chemie (International ed. in English), 2014, Nov-10, Volume: 53, Issue:46

    Topics: Biomarkers, Tumor; Cell Line, Tumor; Equipment Design; Humans; Hydrogen Peroxide; Metal Nanoparticles; Microfluidic Analytical Techniques; Neoplasms; Platinum

2014
Synthesis, in-vitro cytotoxic activity and DNA interactions of new dicarboxylatoplatinum(II) complexes with 2-hydroxymethylbenzimidazole as carrier ligands.
    The Journal of pharmacy and pharmacology, 2014, Volume: 66, Issue:11

    Topics: Antineoplastic Agents; Benzimidazoles; Carboplatin; Cisplatin; DNA; Drug Screening Assays, Antitumor; Estrogens; HeLa Cells; Humans; In Vitro Techniques; Ligands; MCF-7 Cells; Neoplasms; Plasmids; Platinum; Progesterone; Progestins; Restriction Mapping

2014
Platinum(II)-gadolinium(III) complexes as potential single-molecular theranostic agents for cancer treatment.
    Angewandte Chemie (International ed. in English), 2014, Nov-24, Volume: 53, Issue:48

    Topics: Animals; Antineoplastic Agents; Gadolinium; Humans; Mice; Models, Molecular; Neoplasms; Platinum

2014
A feasibility study of the use of saliva as an alternative to leukocytes as a source of DNA for the study of Pt-DNA adducts in cancer patients receiving platinum-based chemotherapy.
    Analytical and bioanalytical chemistry, 2014, Volume: 406, Issue:30

    Topics: Antineoplastic Agents; Cisplatin; DNA Adducts; Humans; Leukocytes; Mass Spectrometry; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Platinum; Saliva

2014
A monofunctional platinum(II)-based anticancer agent from a salicylanilide derivative: Synthesis, antiproliferative activity, and transcription inhibition.
    Journal of inorganic biochemistry, 2015, Volume: 142

    Topics: A549 Cells; Antineoplastic Agents; Cell Proliferation; Coordination Complexes; Drug Screening Assays, Antitumor; HeLa Cells; Humans; MCF-7 Cells; Neoplasms; Platinum; Salicylanilides; Transcription, Genetic

2015
Trifolium-like Platinum Nanoparticle-Mediated Photothermal Therapy Inhibits Tumor Growth and Osteolysis in a Bone Metastasis Model.
    Small (Weinheim an der Bergstrasse, Germany), 2015, May-06, Volume: 11, Issue:17

    Topics: Animals; Biocompatible Materials; Body Weight; Bone Neoplasms; Cell Line; Cell Line, Tumor; HeLa Cells; Humans; Imaging, Three-Dimensional; Infrared Rays; Metal Nanoparticles; Mice; Mice, Nude; Microscopy, Electron, Transmission; Neoplasm Metastasis; Neoplasms; NIH 3T3 Cells; Osteolysis; Photochemistry; Phototherapy; Platinum; Platinum Compounds; Povidone; Tomography, X-Ray Computed; Trifolium; X-Ray Microtomography

2015
Polymeric biomaterials for the delivery of platinum-based anticancer drugs.
    Biomaterials science, 2015, Volume: 3, Issue:7

    Topics: Antineoplastic Agents; Biocompatible Materials; Cisplatin; Drug Delivery Systems; Humans; Nanoparticles; Neoplasms; Platinum; Polymers

2015
In Situ Biosynthesis of Fluorescent Platinum Nanoclusters: Toward Self-Bioimaging-Guided Cancer Theranostics.
    ACS applied materials & interfaces, 2015, Aug-19, Volume: 7, Issue:32

    Topics: Animals; Cell Line; Fluorescent Dyes; HCT116 Cells; HeLa Cells; Hep G2 Cells; Humans; Infrared Rays; Metal Nanoparticles; Mice; Mice, Nude; Microscopy, Confocal; Neoplasms; Phototherapy; Platinum; Platinum Compounds; Porphyrins; Reactive Oxygen Species; Theranostic Nanomedicine; Transplantation, Heterologous

2015
Hepatotoxicity and pharmacokinetics of cisplatin in combination therapy with a traditional Chinese medicine compound of Zengmian Yiliu granules in ICR mice and SKOV-3-bearing nude mice.
    BMC complementary and alternative medicine, 2015, Aug-18, Volume: 15

    Topics: Administration, Oral; Alanine Transaminase; Animals; Antineoplastic Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cisplatin; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Glutathione; Glutathione Transferase; Liver; Male; Medicine, Chinese Traditional; Mice, Inbred ICR; Mice, Nude; Neoplasms; Plants, Medicinal; Platinum; Spleen

2015
Multipronged Design of Light-Triggered Nanoparticles To Overcome Cisplatin Resistance for Efficient Ablation of Resistant Tumor.
    ACS nano, 2015, Oct-27, Volume: 9, Issue:10

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Delayed-Action Preparations; Drug Resistance, Neoplasm; Female; Fluorescent Dyes; Humans; Indoles; Light; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Nanoparticles; Neoplasms; Platinum; Prodrugs; Propionates

2015
Synthesis, luminescence, and anti-tumor properties of MgSiO3:Eu-DOX-DPP-RGD hollow microspheres.
    Dalton transactions (Cambridge, England : 2003), 2015, Nov-14, Volume: 44, Issue:42

    Topics: Animals; Antineoplastic Agents; Cell Survival; Doxorubicin; Drug Carriers; Endocytosis; Erythrocytes; Europium; HeLa Cells; Hemolysis; Humans; Light; Mice; Microspheres; Neoplasms; Oligopeptides; Platinum; Porosity; Prodrugs; Silicon Dioxide; Transplantation, Heterologous

2015
Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug.
    Nature communications, 2015, Oct-27, Volume: 6

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Delivery Systems; Female; Humans; Macrophages; Mice; Mice, Inbred C57BL; Mice, Nude; Nanoparticles; Neoplasms; Platinum; Prodrugs

2015
WO3/Pt nanoparticles are NADPH oxidase biomimetics that mimic effector cells in vitro and in vivo.
    Nanotechnology, 2016, Feb-12, Volume: 27, Issue:6

    Topics: Animals; Apoptosis; Biomimetics; Catalysis; Cell Line; Cell Line, Tumor; Female; Hydroxyl Radical; Light; Mice; Mice, Inbred BALB C; NADPH Oxidases; Nanoparticles; Neoplasms; Oxidation-Reduction; Oxides; Photochemotherapy; Photosensitizing Agents; Platinum; Tungsten

2016
A Potent Glucose-Platinum Conjugate Exploits Glucose Transporters and Preferentially Accumulates in Cancer Cells.
    Angewandte Chemie (International ed. in English), 2016, Feb-12, Volume: 55, Issue:7

    Topics: Cell Line, Tumor; Glucose; Humans; Monosaccharide Transport Proteins; Neoplasms; Platinum

2016
WO3/Pt nanoparticles promote light-induced lipid peroxidation and lysosomal instability within tumor cells.
    Nanotechnology, 2016, Feb-19, Volume: 27, Issue:7

    Topics: Antineoplastic Agents; Cell Line, Tumor; Humans; Light; Lipid Peroxidation; Lysosomes; Nanoparticles; Neoplasms; Oxides; Platinum; Reactive Oxygen Species; Tungsten

2016
Luminescent platinum(II) complexes with functionalized N-heterocyclic carbene or diphosphine selectively probe mismatched and abasic DNA.
    Nature communications, 2016, Feb-17, Volume: 7

    Topics: Base Pair Mismatch; Biosensing Techniques; DNA; Humans; Luminescence; Methane; Neoplasms; Platinum

2016
Platinum(IV) prodrug conjugated Pd@Au nanoplates for chemotherapy and photothermal therapy.
    Nanoscale, 2016, Mar-14, Volume: 8, Issue:10

    Topics: Animals; Antineoplastic Agents; Ascorbic Acid; Cell Line; Cisplatin; Drug Carriers; Drug Delivery Systems; Drug Therapy; Female; Glutathione; Gold; HeLa Cells; Humans; Metal Nanoparticles; Mice; Mice, Inbred BALB C; Microscopy, Electron, Transmission; Nanocomposites; Nanotechnology; Neoplasms; Phototherapy; Platinum; Prodrugs; Spectroscopy, Near-Infrared

2016
Platinum anti-cancer drugs: Free radical mechanism of Pt-DNA adduct formation and anti-neoplastic effect.
    Free radical biology & medicine, 2016, Volume: 95

    Topics: Anions; Antineoplastic Agents; Cisplatin; DNA Adducts; DNA Damage; Electron Transport; Free Radicals; Humans; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Platinum

2016
Improving proton therapy by metal-containing nanoparticles: nanoscale insights.
    International journal of nanomedicine, 2016, Volume: 11

    Topics: DNA; Gadolinium; Humans; Metal Nanoparticles; Molecular Probes; Neoplasms; Plasmids; Platinum; Proton Therapy; Protons

2016
Synthesis and Characterization of Novel Cu(II), Pd(II) and Pt(II) Complexes with 8-Ethyl-2-hydroxytricyclo(7.3.1.0(2,7))tridecan-13-one-thiosemicarbazone: Antimicrobial and in Vitro Antiproliferative Activity.
    Molecules (Basel, Switzerland), 2016, May-21, Volume: 21, Issue:5

    Topics: Cell Proliferation; Coordination Complexes; Copper; Escherichia coli; HL-60 Cells; Humans; Infections; MCF-7 Cells; Neoplasms; Palladium; Platinum; Staphylococcus aureus

2016
Safety and feasibility of fasting in combination with platinum-based chemotherapy.
    BMC cancer, 2016, 06-10, Volume: 16

    Topics: Adult; Aged; Biomarkers; Fasting; Feasibility Studies; Female; Humans; Insulin-Like Growth Factor I; Male; Middle Aged; Neoplasms; Oxidative Stress; Platinum; Treatment Outcome

2016
Could nanoparticles that mimic the NADPH oxidase be used to kill tumor cells?
    Nanomedicine (London, England), 2016, Volume: 11, Issue:13

    Topics: Animals; Humans; Metal Nanoparticles; Molecular Mimicry; NADPH Oxidases; Nanomedicine; Nanotechnology; Neoplasms; Oxides; Photochemotherapy; Platinum; Reactive Oxygen Species; Tungsten

2016
Self-Assembly of Amphiphilic Drug-Dye Conjugates into Nanoparticles for Imaging and Chemotherapy.
    Chemistry, an Asian journal, 2016, Nov-22, Volume: 11, Issue:22

    Topics: A549 Cells; Antineoplastic Agents, Phytogenic; Cell Survival; Coloring Agents; Coordination Complexes; Humans; MCF-7 Cells; Microscopy, Confocal; Nanoparticles; Neoplasms; Paclitaxel; Particle Size; Platinum; Spectrophotometry, Ultraviolet

2016
Bifunctional Platinated Nanoparticles for Photoinduced Tumor Ablation.
    Advanced materials (Deerfield Beach, Fla.), 2016, Volume: 28, Issue:46

    Topics: Animals; Cell Line, Tumor; Hyperthermia, Induced; Metal Nanoparticles; Mice; Nanomedicine; Neoplasms; Photochemotherapy; Platinum; Singlet Oxygen

2016
A Platinum(IV) Anticancer Prodrug Targeting Nucleotide Excision Repair To Overcome Cisplatin Resistance.
    Angewandte Chemie (International ed. in English), 2016, 12-12, Volume: 55, Issue:50

    Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cisplatin; DNA Repair; Drug Discovery; Drug Resistance, Neoplasm; Humans; Neoplasms; Platinum; Prodrugs

2016
Microdose-Induced Drug-DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice.
    Molecular cancer therapeutics, 2017, Volume: 16, Issue:2

    Topics: Animals; Antineoplastic Agents; Biomarkers; Carboplatin; Cell Line, Tumor; Deoxycytidine; Disease Models, Animal; DNA Adducts; DNA Repair; Drug Resistance, Neoplasm; Drug Synergism; Female; Gemcitabine; Humans; Mass Spectrometry; Mice; Mutation; Neoplasms; Platinum; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays

2017
Photoactive platinum diimine complexes showing induced cancer cell death by apoptosis.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2017, Volume: 30, Issue:1

    Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Coordination Complexes; Humans; Light; Neoplasms; Photosensitizing Agents; Platinum; Platinum Compounds

2017
Cytotoxicity and cellular response mechanisms of water-soluble platinum(II) complexes of lidocaine and phenylcyanamide derivatives.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2017, Volume: 30, Issue:1

    Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Cell Proliferation; Cisplatin; Cyanamide; DNA; Hep G2 Cells; Humans; Lidocaine; Neoplasms; Organoplatinum Compounds; Platinum; Solubility; Water

2017
Evaluation of cell lysis methods for platinum metallomic studies of human malignant cells.
    Analytical biochemistry, 2010, Jan-01, Volume: 396, Issue:1

    Topics: Cell Death; Cell Extracts; Cell Fractionation; Cell Line, Tumor; Cell Separation; Chromatography, Liquid; Cisplatin; Freezing; Humans; Metabolomics; Neoplasm Proteins; Neoplasms; Osmosis; Platinum; Reproducibility of Results; Spectrophotometry, Atomic

2010
FePt nanoparticles as an Fe reservoir for controlled Fe release and tumor inhibition.
    Journal of the American Chemical Society, 2009, Oct-28, Volume: 131, Issue:42

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Gonadotropin-Releasing Hormone; Humans; Iron; Metal Nanoparticles; Microscopy, Electron, Transmission; Neoplasms; Platinum

2009
Geant4 estimation model of high Z atom concentration for tumor vessel ablation.
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2009, Volume: 2009

    Topics: Algorithms; Apoptosis; Computer Simulation; Endothelial Cells; Gadolinium; Gold; Humans; Monte Carlo Method; Neoplasms; Photons; Platinum; Radiation Dosage; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Software; Uranium

2009
The Midas touch in cancer chemotherapy: from platinum- to gold-dithiocarbamato complexes.
    Dalton transactions (Cambridge, England : 2003), 2009, Dec-28, Issue:48

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Coordination Complexes; Drug Screening Assays, Antitumor; Gold; Humans; Mice; Neoplasms; Platinum; Ruthenium; Thiocarbamates

2009
Platinum nanoparticles: a promising material for future cancer therapy?
    Nanotechnology, 2010, Feb-26, Volume: 21, Issue:8

    Topics: DNA Damage; DNA, Superhelical; Metal Nanoparticles; Neoplasms; Organoplatinum Compounds; Platinum; Radiation-Sensitizing Agents; Radiation, Ionizing

2010
New platinum-oxicam complexes as anti-cancer drugs. Synthesis, characterization, release studies from smart hydrogels, evaluation of reactivity with selected proteins and cytotoxic activity in vitro.
    Journal of inorganic biochemistry, 2010, Volume: 104, Issue:8

    Topics: Antineoplastic Agents; Cell Proliferation; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Hydrogels; Meloxicam; Neoplasm Proteins; Neoplasms; Platinum; Thiazines; Thiazoles

2010
The status of platinum anticancer drugs in the clinic and in clinical trials.
    Dalton transactions (Cambridge, England : 2003), 2010, Sep-21, Volume: 39, Issue:35

    Topics: Antineoplastic Agents; Clinical Trials as Topic; Coordination Complexes; Humans; Neoplasms; Platinum

2010
Harnessing structure-activity relationship to engineer a cisplatin nanoparticle for enhanced antitumor efficacy.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Jul-13, Volume: 107, Issue:28

    Topics: Animals; Carboplatin; Cisplatin; Inhibitory Concentration 50; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nanoparticles; Nanotechnology; Neoplasms; Platinum; Polyenes; Polymers; Raloxifene Hydrochloride; Structure-Activity Relationship; Tissue Distribution

2010
Interrogation of nucleotide excision repair capacity: impact on platinum-based cancer therapy.
    Antioxidants & redox signaling, 2011, Jun-15, Volume: 14, Issue:12

    Topics: Antineoplastic Agents; Cisplatin; DNA Damage; DNA Repair; DNA-Binding Proteins; Enzyme-Linked Immunosorbent Assay; HeLa Cells; Humans; Neoplasms; Platinum; Replication Protein A; Xeroderma Pigmentosum Group A Protein

2011
Antitumor effects of nano-bubble hydrogen-dissolved water are enhanced by coexistent platinum colloid and the combined hyperthermia with apoptosis-like cell death.
    Oncology reports, 2010, Volume: 24, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Death; Cells, Cultured; Colloids; Combined Modality Therapy; Drug Synergism; Gases; Humans; Hydrogen; Hyperthermia, Induced; Models, Biological; Nanoparticles; Neoplasms; Platinum; Solubility; Water

2010
Platinum resistant cancer cells conserve sensitivity to BH3 domains and obatoclax induced mitochondrial apoptosis.
    Apoptosis : an international journal on programmed cell death, 2011, Volume: 16, Issue:3

    Topics: Adenosine Triphosphate; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Blotting, Western; Cell Line, Tumor; Cell Survival; Cisplatin; DNA Damage; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Indoles; Mitochondria; Neoplasms; Peptides; Platinum; Protein Structure, Tertiary; Protein Transport; Pyrroles

2011
NMR studies of models having the Pt(d(GpG)) 17-membered macrocyclic ring formed in DNA by platinum anticancer drugs: Pt complexes with bulky chiral diamine ligands.
    Inorganic chemistry, 2011, May-16, Volume: 50, Issue:10

    Topics: Antineoplastic Agents; Circular Dichroism; Cisplatin; Dinucleoside Phosphates; DNA; DNA Adducts; Guanine; Macrocyclic Compounds; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Motion; Neoplasms; Platinum; Putrescine; Stereoisomerism

2011
Development of highly effective three-component cytoprotective adjuncts for cisplatin cancer treatment: synthesis and in vivo evaluation in S180-bearing mice.
    Metallomics : integrated biometal science, 2011, Volume: 3, Issue:11

    Topics: Amino Acids; Animals; Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Cytoprotection; Humans; Mice; Molecular Structure; Neoplasms; Neoplasms, Experimental; Platinum; Thiocarbamates; Tissue Distribution

2011
Monofunctional platinum complexes containing a 4-nitrobenzo-2-oxa-1,3-diazole fluorophore: distribution in tumour cells.
    Dalton transactions (Cambridge, England : 2003), 2011, Oct-28, Volume: 40, Issue:40

    Topics: Antineoplastic Agents; Cell Line, Tumor; Coordination Complexes; Crystallography, X-Ray; Humans; Isomerism; Microscopy, Confocal; Molecular Conformation; Neoplasms; Oxadiazoles; Platinum; Spectrometry, Fluorescence

2011
Studies of glutathione transferase P1-1 bound to a platinum(IV)-based anticancer compound reveal the molecular basis of its activation.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2011, Jul-04, Volume: 17, Issue:28

    Topics: Animals; Antineoplastic Agents; Cisplatin; Crystallography, X-Ray; Dimerization; Enzyme Inhibitors; Ethacrynic Acid; Glutathione S-Transferase pi; Humans; Models, Molecular; Molecular Dynamics Simulation; Molecular Sequence Data; Molecular Structure; Neoplasms; Platinum; Protein Binding; Protein Conformation; Recombinant Proteins

2011
Systolic and diastolic dysfunction in long-term adult survivors of childhood cancer.
    European journal of cancer (Oxford, England : 1990), 2011, Volume: 47, Issue:16

    Topics: Adolescent; Adult; Anthracyclines; Baroreflex; Biomarkers; Cohort Studies; Diastole; Electrocardiography; Female; Humans; Logistic Models; Male; Middle Aged; Myocardial Contraction; Natriuretic Peptide, Brain; Neoplasms; Peptide Fragments; Platinum; Radiotherapy; Survivors; Systole; Ventricular Dysfunction, Left; Young Adult

2011
Synthesis, characterization, and cytotoxic activity of novel potentially pH-sensitive nonclassical platinum(II) complexes featuring 1,3-dihydroxyacetone oxime ligands.
    Inorganic chemistry, 2011, 11-07, Volume: 50, Issue:21

    Topics: Antineoplastic Agents; Cell Line, Tumor; Chelating Agents; Crystallography, X-Ray; Dihydroxyacetone; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Models, Molecular; Neoplasms; Organoplatinum Compounds; Oximes; Platinum; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship

2011
Synthesis, cytotoxicity and structure-activity relationships between ester and amide functionalities in novel acridine-based platinum(II) complexes.
    Journal of inorganic biochemistry, 2012, Volume: 110

    Topics: Acridines; Antineoplastic Agents; Cell Line, Tumor; Cytotoxins; Humans; Neoplasms; Platinum

2012
Platinum(IV)-chlorotoxin (CTX) conjugates for targeting cancer cells.
    Journal of inorganic biochemistry, 2012, Volume: 110

    Topics: Antineoplastic Agents; Drug Delivery Systems; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Neoplasms; Platinum; Scorpion Venoms

2012
Carbon nanospheres-promoted electrochemical immunoassay coupled with hollow platinum nanolabels for sensitivity enhancement.
    Biosensors & bioelectronics, 2012, May-15, Volume: 35, Issue:1

    Topics: Biosensing Techniques; Carcinoembryonic Antigen; Electrochemical Techniques; Graphite; Horseradish Peroxidase; Humans; Immunoassay; Nanoshells; Nanospheres; Nanotechnology; Nanotubes, Carbon; Neoplasms; Platinum; Sensitivity and Specificity

2012
Interaction between serotonin reuptake inhibitors, 5-HT3 antagonists, and NK1 antagonists in cancer patients receiving highly emetogenic chemotherapy: a case-control study.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2012, Volume: 20, Issue:9

    Topics: Adult; Aged; Antiemetics; Antineoplastic Agents, Phytogenic; Aprepitant; Case-Control Studies; Drug Interactions; Drug Therapy, Combination; Etoposide; Female; Humans; Male; Middle Aged; Morpholines; Nausea; Neoplasms; Platinum; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Vomiting

2012
Structural and anticancer properties of hydrogen bonded diphenyl phosphate adducts of Pt(IV) complexes: the importance of pKa matching.
    Journal of inorganic biochemistry, 2012, Volume: 115

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Crystallography, X-Ray; Dose-Response Relationship, Drug; Female; Humans; Hydrogen Bonding; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Organophosphonates; Platinum; Xenograft Model Antitumor Assays

2012
Dinuclear Pt(II)-bisphosphonate complexes: a scaffold for multinuclear or different oxidation state platinum drugs.
    Dalton transactions (Cambridge, England : 2003), 2012, Aug-28, Volume: 41, Issue:32

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Coordination Complexes; Crystallography, X-Ray; Diphosphonates; Humans; Neoplasms; Oxidation-Reduction; Platinum; Rats

2012
Characterization of metalloanticancer capacity of an agglutinin from wheat.
    Molecular bioSystems, 2012, Volume: 8, Issue:10

    Topics: Anilino Naphthalenesulfonates; Antineoplastic Agents, Phytogenic; Binding Sites; Cisplatin; Drug Carriers; Fluorescent Dyes; Gold; Humans; Kinetics; Metalloporphyrins; Neoplasms; Platinum; Protein Binding; Solutions; Spectrometry, Fluorescence; Wheat Germ Agglutinins

2012
Pt(II) squares as selective and effective human telomeric G-quadruplex binders and potential cancer therapeutics.
    Dalton transactions (Cambridge, England : 2003), 2012, Oct-14, Volume: 41, Issue:38

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Circular Dichroism; Coordination Complexes; G-Quadruplexes; Humans; Neoplasms; Organoplatinum Compounds; Platinum; Telomerase; Thermodynamics

2012
The prevalence of metal-based drugs as therapeutic or diagnostic agents: beyond platinum.
    Dalton transactions (Cambridge, England : 2003), 2012, Nov-21, Volume: 41, Issue:43

    Topics: Anti-Arrhythmia Agents; Anti-Infective Agents; Antineoplastic Agents; Antiprotozoal Agents; Bacteria; Contrast Media; Coordination Complexes; Fungi; Humans; Leishmania; Magnetic Resonance Imaging; Metals; Neoplasms; Oncogene Proteins, Fusion; Platinum; Positron-Emission Tomography; Protein Binding; Radiography; Radiopharmaceuticals

2012
Syntheses, characterization, and antitumor activities of platinum(II) and palladium(II) complexes with sugar-conjugated triazole ligands.
    Chemistry & biodiversity, 2012, Volume: 9, Issue:9

    Topics: Antineoplastic Agents; Carbohydrates; Cisplatin; Coordination Complexes; Crystallography, X-Ray; HeLa Cells; Humans; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Neoplasms; Palladium; Platinum; Triazoles

2012
External heavy-atomic construction of photosensitizer nanoparticles for enhanced in vitro photodynamic therapy of cancer.
    The journal of physical chemistry. B, 2012, Oct-25, Volume: 116, Issue:42

    Topics: Antineoplastic Agents; Cell Death; Cell Survival; Drug Delivery Systems; Gold; HeLa Cells; Humans; Nanoparticles; Neoplasms; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Platinum; Quinones; Silicon Dioxide; Singlet Oxygen; Structure-Activity Relationship; Tumor Cells, Cultured

2012
Prevention and handling of acute allergic and infusion reactions in oncology.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23 Suppl 10

    Topics: Anaphylaxis; Antibodies, Monoclonal; Asparaginase; Drug Hypersensitivity; Humans; Immunoglobulin E; Neoplasms; Platinum; Podophyllotoxin; Procarbazine; Taxoids

2012
Nanoparticles: the future for platinum drugs or a research red herring?
    Nanomedicine (London, England), 2012, Volume: 7, Issue:9

    Topics: Antineoplastic Agents; Drug Delivery Systems; Humans; Nanoparticles; Neoplasms; Organoplatinum Compounds; Platinum

2012
Using a build-and-click approach for producing structural and functional diversity in DNA-targeted hybrid anticancer agents.
    Journal of medicinal chemistry, 2012, Nov-26, Volume: 55, Issue:22

    Topics: Acridines; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; DNA; Drug Design; Drug Screening Assays, Antitumor; Humans; Neoplasms; Platinum; Small Molecule Libraries; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship

2012
Antimicrobial and antitumor activity of platinum and palladium complexes of novel spherical aramides nanoparticles containing flexibilizing linkages: structure-property relationship.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2013, Feb-15, Volume: 103

    Topics: Anti-Infective Agents; Antineoplastic Agents; Bacteria; Bacterial Infections; Cell Line, Tumor; Coordination Complexes; Fungi; Humans; Mycoses; Nanoparticles; Neoplasms; Nylons; Palladium; Platinum

2013
Platinum folate nanoparticles toxicity: cancer vs. normal cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2013, Volume: 27, Issue:2

    Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Cells, Cultured; Folic Acid; Humans; Keratinocytes; Metal Nanoparticles; Microscopy, Electron, Transmission; Necrosis; Neoplasms; Platinum

2013
[Surfacant sensitizing kinetic spectrophotometric determination of trace platinum].
    Guang pu xue yu guang pu fen xi = Guang pu, 2000, Volume: 20, Issue:3

    Topics: Antineoplastic Agents; Cisplatin; Humans; Kinetics; Neoplasms; Platinum; Spectrophotometry; Surface-Active Agents

2000
Tautomeric equilibrium in nitro-9[(alkylamino)amino]acridines: the role of metal ions and hydrogen bond acceptors.
    Oftalmologia (Bucharest, Romania : 1990), 2003, Volume: 57, Issue:2

    Topics: Aminoacridines; Antineoplastic Agents; Humans; Hydrogen Bonding; Isomerism; Ligands; Molecular Conformation; Neoplasms; Nitracrine; Platinum

2003
[Bioelectrostatic hypotheses for new methods in the therapeutic use of peteosthor in cancer and tuberculosis].
    Therapie der Gegenwart, 1950, Volume: 89, Issue:9

    Topics: Neoplasms; Platinum; Thorium; Tuberculosis

1950
Effect of glomerular filtration rate on clearance and myelotoxicity of carboplatin in cats with tumors.
    American journal of veterinary research, 2004, Volume: 65, Issue:11

    Topics: Animals; Area Under Curve; Blood Cell Count; Blood Platelets; Carboplatin; Cat Diseases; Cats; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Neoplasms; Neutrophils; Platinum; Regression Analysis; Spectrophotometry, Atomic; Technetium Tc 99m Pentetate

2004
Small interfering RNA-induced suppression of ERCC1 enhances sensitivity of human cancer cells to cisplatin.
    Biochemical and biophysical research communications, 2005, Feb-04, Volume: 327, Issue:1

    Topics: Cell Line, Tumor; Cell Proliferation; Cisplatin; DNA Repair; DNA-Binding Proteins; Down-Regulation; Endonucleases; Humans; Neoplasms; Platinum; RNA Interference; RNA, Small Interfering

2005
A novel platinum compound inhibits constitutive Stat3 signaling and induces cell cycle arrest and apoptosis of malignant cells.
    The Journal of biological chemistry, 2005, Sep-23, Volume: 280, Issue:38

    Topics: Agar; Animals; Apoptosis; Blotting, Western; Bromodeoxyuridine; Cell Cycle; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cyclin D1; Cytosol; DNA; Fibroblasts; Flow Cytometry; G1 Phase; Gene Expression Regulation; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Ki-67 Antigen; Kinetics; Luciferases; Mice; Neoplasms; NIH 3T3 Cells; Oligonucleotides; Oncogene Protein pp60(v-src); Piperazines; Plasmids; Platinum; Platinum Compounds; Protein Binding; Resting Phase, Cell Cycle; Signal Transduction; Time Factors

2005
High performance liquid chromatographic determination of platinum in blood and urine samples of cancer patients after administration of cisplatin drug using solvent extraction and N,N'-bis(salicylidene)-1,2-propanediamine as complexation reagent.
    Journal of pharmaceutical and biomedical analysis, 2006, Mar-03, Volume: 40, Issue:4

    Topics: Antineoplastic Agents; Chelating Agents; Chromatography, High Pressure Liquid; Cisplatin; Diamines; Humans; Indicators and Reagents; Neoplasms; Platinum; Schiff Bases; Spectrophotometry, Ultraviolet

2006
Light-activated destruction of cancer cell nuclei by platinum diazide complexes.
    Chemistry & biology, 2006, Volume: 13, Issue:1

    Topics: Antineoplastic Agents; Azides; Cell Line, Tumor; Cell Nucleus; DNA; Humans; Inhibitory Concentration 50; Light; Molecular Structure; Neoplasms; Photosensitizing Agents; Platinum; Spectrum Analysis; Temperature

2006
Gamma camera scintigraphy of tumours using (195m)Pt-cisplatin.
    Physics in medicine and biology, 2006, Mar-07, Volume: 51, Issue:5

    Topics: Antineoplastic Agents; Cisplatin; Feasibility Studies; Gamma Cameras; Gold Radioisotopes; Humans; Iridium Radioisotopes; Neoplasms; Phantoms, Imaging; Platinum; Radioisotopes; Tomography, Emission-Computed, Single-Photon

2006
Molecular aspects of antitumor effects of a new platinum(IV) drug.
    Molecular pharmacology, 2006, Volume: 70, Issue:5

    Topics: Adamantane; Animals; Antineoplastic Agents; Ascorbic Acid; Base Sequence; Cell Line, Tumor; Cell-Free System; Cross-Linking Reagents; DNA; DNA Adducts; DNA Repair; DNA-Directed RNA Polymerases; HeLa Cells; High Mobility Group Proteins; HIV-1; Humans; Molecular Sequence Data; Neoplasms; Organoplatinum Compounds; Plasmids; Platinum; Rats; RNA-Directed DNA Polymerase; Sulfur Compounds; Viral Proteins

2006
Evaluation of carboplatin pharmacokinetics in pediatric oncology by means of inductively coupled plasma mass spectrometry.
    Annali dell'Istituto superiore di sanita, 2006, Volume: 42, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Agents; Area Under Curve; Brain Neoplasms; Carboplatin; Child; Child, Preschool; Female; Humans; Male; Mass Spectrometry; Myosarcoma; Neoplasms; Neoplasms, Muscle Tissue; Platinum; Rhabdomyosarcoma

2006
Evaluation of corrosion behaviors and surface profiles of platinum-coated electrodes by electrochemistry and complementary microscopy: biomedical implications for anticancer therapy.
    Micron (Oxford, England : 1993), 2007, Volume: 38, Issue:7

    Topics: Animals; Corrosion; Electrochemistry; Electrochemotherapy; Electrodes; Female; Mice; Mice, Nude; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Neoplasms; Platinum

2007
Optimization of (1,2-diamino-cyclohexane)platinum(II)-loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity.
    Journal of controlled release : official journal of the Controlled Release Society, 2007, Aug-28, Volume: 121, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Female; HeLa Cells; Humans; Mice; Mice, SCID; Micelles; Neoplasms; Organoplatinum Compounds; Platinum; Polymers; Xenograft Model Antitumor Assays

2007
Oxaliplatin pharmacokinetics and pharmacodynamics in adult cancer patients with impaired renal function.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Aug-15, Volume: 13, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Creatinine; Dose-Response Relationship, Drug; Female; Humans; Kidney Diseases; Male; Middle Aged; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Platinum

2007
Conjugated platinum(IV)-peptide complexes for targeting angiogenic tumor vasculature.
    Bioconjugate chemistry, 2008, Volume: 19, Issue:1

    Topics: Amino Acid Motifs; Animals; Cattle; CD13 Antigens; Cell Line, Tumor; Cell Proliferation; Cisplatin; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Inhibitory Concentration 50; Integrin alphaV; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Organometallic Compounds; Peptides; Platinum

2008
[Predictive markers for platinum-based chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:2

    Topics: Apoptosis; Biomarkers, Tumor; DNA Repair; Drug Resistance; Humans; Neoplasms; Platinum; Prognosis

2008
[Development of antitumor platinum complexes].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:12

    Topics: Animals; Antineoplastic Agents; Carboplatin; Cisplatin; Cyclohexylamines; Humans; Kidney; Neoplasms; Neoplasms, Experimental; Organoplatinum Compounds; Platinum; Structure-Activity Relationship

1983
Pharmacokinetics of cis-diammine-1,1-cyclobutane dicarboxylate platinum(II) in patients with normal and impaired renal function.
    Cancer research, 1984, Volume: 44, Issue:4

    Topics: Antineoplastic Agents; Carboplatin; Drug Evaluation; Humans; Kidney; Kinetics; Neoplasms; Organoplatinum Compounds; Platinum

1984
Phase I clinical and pharmacologic trial of carboplatin daily for 5 days.
    Cancer treatment reports, 1984, Volume: 68, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents; Carboplatin; Drug Evaluation; Female; Humans; Kinetics; Male; Middle Aged; Neoplasms; Organoplatinum Compounds; Platinum; Pleural Effusion; Thrombocytopenia

1984
Pharmacokinetics of free and total platinum species after short-term infusion of cisplatin.
    Cancer treatment reports, 1984, Volume: 68, Issue:3

    Topics: Adult; Aged; Blood Proteins; Cisplatin; Enterohepatic Circulation; Erythrocytes; Female; Half-Life; Humans; Kinetics; Male; Middle Aged; Neoplasms; Platinum; Protein Binding

1984
Plasma platinum levels: relationship to cisplatin dose and nephrotoxicity.
    Cancer treatment reports, 1983, Volume: 67, Issue:2

    Topics: Cisplatin; Creatinine; Dose-Response Relationship, Drug; Female; Humans; Infusions, Parenteral; Kidney; Male; Middle Aged; Neoplasms; Platinum; Time Factors

1983
Renal failure and platinum pharmacokinetics in three patients treated with cis-diamminedichloroplatinum(II) and whole-body hyperthermia.
    Cancer chemotherapy and pharmacology, 1983, Volume: 11, Issue:3

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Cisplatin; Creatinine; Humans; Hyperthermia, Induced; Kinetics; Male; Neoplasms; Platinum

1983
Platinum-complexed antitumor immunoglobulins that specifically inhibit DNA synthesis of mouse tumor cells.
    Journal of the National Cancer Institute, 1982, Volume: 69, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigen-Antibody Complex; Cytotoxicity, Immunologic; DNA Replication; Goats; Immunoglobulins; Leukemia, Experimental; Male; Mice; Mice, Inbred Strains; Neoplasms; Platinum

1982
Blood clearance of three radioactively labelled platinum complexes: cis-dichlorodiammine platinum II, cis, trans-dichlorodihydroxy-bis-(isopropylamine) platinum IV, and cis-dichloro-bis-cyclopropylamine platinum II, in patients with malignant disease.
    Cancer chemotherapy and pharmacology, 1982, Volume: 9, Issue:1

    Topics: Aged; Cisplatin; Female; Half-Life; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Organoplatinum Compounds; Platinum; Radioisotopes; Solubility; Time Factors

1982
Pharmacokinetic study of Cis-dichlorodiammine platinum II, in children after rapid infusion.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1981, Volume: 34, Issue:3

    Topics: Adolescent; Child; Cisplatin; Female; Half-Life; Humans; Infant; Kinetics; Male; Mathematics; Neoplasms; Platinum

1981
Renal excretion of magnesium and trace elements during cisplatin treatment.
    Clinical nephrology, 1982, Volume: 17, Issue:5

    Topics: Cisplatin; Copper; Humans; Kidney; Magnesium; Neoplasms; Platinum; Trace Elements; Zinc

1982
Circadian time dependence of cisplatin urinary kinetics.
    Clinical pharmacology and therapeutics, 1982, Volume: 32, Issue:3

    Topics: Adult; Aged; Animals; Body Temperature; Circadian Rhythm; Cisplatin; Female; Humans; Kinetics; Male; Mice; Middle Aged; Neoplasms; Platinum; Urination

1982
Absence of whole body hyperthermia effect on cisplatin distribution in spontaneous canine tumors.
    International journal of radiation oncology, biology, physics, 1995, Jul-15, Volume: 32, Issue:4

    Topics: Animals; Cisplatin; Combined Modality Therapy; Dogs; Hyperthermia, Induced; Neoplasms; Platinum

1995
Modeling analysis of platinum-195m for targeting individual blood-borne cells in adjuvant radioimmunotherapy.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1995, Volume: 36, Issue:2

    Topics: Blood Cells; Bone Marrow; Bone Marrow Cells; Humans; Isotopes; Neoplasms; Platinum; Radiation Dosage; Radiation Tolerance; Radioimmunotherapy; Radionuclide Imaging; Tumor Cells, Cultured

1995
Current sample handling methods for measurement of platinum-DNA adducts in leucocytes in man lead to discrepant results in DNA adduct levels and DNA repair.
    British journal of cancer, 1995, Volume: 71, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Specimen Collection; Carboplatin; Cisplatin; DNA Adducts; DNA Repair; DNA, Neoplasm; Etoposide; Humans; Kinetics; Leukocytes; Neoplasms; Platinum

1995
Factors affecting platinum concentrations in human surgical tumour specimens after cisplatin.
    British journal of cancer, 1995, Volume: 71, Issue:3

    Topics: Blood-Brain Barrier; Brain Neoplasms; Cerebellar Neoplasms; Cisplatin; Combined Modality Therapy; Dose-Response Relationship, Drug; Female; Humans; Lymphoma; Male; Medulloblastoma; Meningioma; Middle Aged; Neoplasms; Platinum

1995
Radiotoxicity of platinum-195m-labeled trans-platinum (II) in mammalian cells.
    Radiation research, 1994, Volume: 140, Issue:1

    Topics: Animals; Cell Survival; Cells, Cultured; Cisplatin; Combined Modality Therapy; Cricetinae; Neoplasms; Platinum; Radiation Dosage; Radioisotopes; Relative Biological Effectiveness

1994
Urinary platinum in hospital personnel occupationally exposed to platinum-containing antineoplastic drugs.
    International archives of occupational and environmental health, 1994, Volume: 65, Issue:5

    Topics: Adult; Antineoplastic Agents; Dose-Response Relationship, Drug; Environmental Monitoring; Female; Humans; Male; Middle Aged; Neoplasms; Occupational Exposure; Organoplatinum Compounds; Patient Care Team; Platinum; Risk Factors

1994
Drug-induced DNA modification in buccal cells of cancer patients receiving carboplatin and cisplatin combination chemotherapy, as determined by an immunocytochemical method: interindividual variation and correlation with disease response.
    Cancer research, 1993, Dec-01, Volume: 53, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; DNA; Dose-Response Relationship, Drug; Female; Humans; Immunohistochemistry; Male; Middle Aged; Mouth Mucosa; Neoplasms; Pilot Projects; Platinum

1993
Noninvasive follow-up of platinum pharmacokinetics in the skin of patients on cisplatin chemotherapy.
    Cancer, 1993, Jul-15, Volume: 72, Issue:2

    Topics: Cisplatin; Dose-Response Relationship, Drug; Humans; Male; Mathematics; Neoplasms; Platinum; Skin; Spectrometry, X-Ray Emission; Spectrophotometry, Atomic

1993
A pilot study using 99mTc to measure lead and platinum in the human kidney.
    Nuclear medicine and biology, 1993, Volume: 20, Issue:5

    Topics: Cisplatin; Female; Humans; Kidney; Lead; Male; Neoplasms; Pilot Projects; Platinum; Radionuclide Imaging; Spectrometry, X-Ray Emission; Technetium

1993
Response to Dr. Dewhirst.
    International journal of radiation oncology, biology, physics, 1993, Mar-15, Volume: 25, Issue:4

    Topics: Antineoplastic Agents; Hot Temperature; Humans; Hyperthermia, Induced; Neoplasms; Platinum; Tumor Cells, Cultured

1993
A Bayesian dosing method for carboplatin given by continuous infusion for 120 h.
    Cancer chemotherapy and pharmacology, 1997, Volume: 40, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Carboplatin; Drug Administration Schedule; Drug Tolerance; Female; Humans; Infusions, Parenteral; Male; Middle Aged; Neoplasms; Platinum

1997
High-performance liquid chromatographic determination of cisplatin as platinum(II) in a pharmaceutical preparation and blood samples of cancer patients.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, May-23, Volume: 693, Issue:1

    Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Cisplatin; Dosage Forms; Humans; Indicators and Reagents; Neoplasms; Organoplatinum Compounds; Platinum; Spectrophotometry, Ultraviolet

1997
Association of cisplatin nephrotoxicity with patient characteristics and cisplatin administration methods.
    Cancer chemotherapy and pharmacology, 1997, Volume: 40, Issue:4

    Topics: Antineoplastic Agents; Cisplatin; Creatinine; Female; Humans; Kidney; Kidney Diseases; Logistic Models; Male; Neoplasms; Platinum; Retrospective Studies; Risk Factors

1997
Cisplatin pharmacokinetics in children with cancer.
    European journal of cancer (Oxford, England : 1990), 1997, Volume: 33, Issue:11

    Topics: Adolescent; Adult; Antineoplastic Agents; Child; Child, Preschool; Cisplatin; Dose-Response Relationship, Drug; Female; Humans; Infant; Male; Neoplasms; Platinum

1997
Gamma camera imaging of platinum in tumours and tissues of patients after administration of 191Pt-cisplatin.
    Acta oncologica (Stockholm, Sweden), 1999, Volume: 38, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Cisplatin; Female; Gamma Cameras; Humans; Male; Middle Aged; Neoplasms; Platinum; Radiation-Sensitizing Agents; Radioisotopes; Radionuclide Imaging; Radiopharmaceuticals

1999
[Pharmacologic markers predictive of neutropenia chemically induced by cisplatin (CDDP)].
    Journal de la Societe de biologie, 1999, Volume: 193, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Choriocarcinoma; Cisplatin; DNA Adducts; Drug Monitoring; Female; Fluorouracil; Humans; Lymphocytes; Male; Middle Aged; Neoplasms; Neutropenia; Ovarian Neoplasms; Platinum; Predictive Value of Tests; Saliva

1999
In vivo measurement of platinum in the kidneys using X-ray fluorescence.
    Annals of the New York Academy of Sciences, 2000, Volume: 904

    Topics: Antineoplastic Agents; Carboplatin; Cisplatin; Humans; Kidney; Neoplasms; Organoplatinum Compounds; Photons; Platinum; Scattering, Radiation; Sensitivity and Specificity; Spectrometry, X-Ray Emission

2000
Mathematical modelling of physicochemical reactions and transport processes occurring around a platinum cathode during the electrochemical treatment of tumours.
    Bioelectrochemistry (Amsterdam, Netherlands), 2001, Volume: 53, Issue:2

    Topics: Animals; Bicarbonates; Buffers; Electrochemistry; Models, Theoretical; Neoplasms; Platinum; Rats; Sodium Chloride

2001
Population pharmacokinetic analysis of cisplatin and its metabolites in cancer patients: possible misinterpretation of covariates for pharmacokinetic parameters calculated from the concentrations of unchanged cisplatin, ultrafiltered platinum and total pl
    Japanese journal of clinical oncology, 2001, Volume: 31, Issue:5

    Topics: Aged; Antineoplastic Agents; Cisplatin; Demography; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Models, Biological; Neoplasms; Platinum; Ultrafiltration

2001
A christmas carol.
    Genome biology, 2002, Volume: 3, Issue:1

    Topics: Antineoplastic Agents; Cisplatin; Escherichia coli; History, 20th Century; Humans; Neoplasms; Platinum; United States

2002
Synthesis and selective tumor targeting properties of water soluble porphyrin-Pt(II) conjugates.
    Journal of inorganic biochemistry, 2002, Apr-10, Volume: 89, Issue:1-2

    Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Mice; Neoplasm Transplantation; Neoplasms; Organ Specificity; Platinum; Porphyrins; Substrate Specificity; Tissue Distribution; Tumor Cells, Cultured

2002
Overview of early and investigational chemotherapeutic agents in solid tumors.
    Medical and pediatric oncology, 1976, Volume: 2, Issue:4

    Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Aziridines; Azo Compounds; Camptothecin; Cycloleucine; Etoposide; Floxuridine; Humans; Neoplasms; Nitrogen Mustard Compounds; Picolinic Acids; Platinum; Porfiromycin; Streptonigrin; Teniposide; Thiotepa; Tubercidin

1976
Potential carcinostatic activity of metal complexes.
    Advances in experimental medicine and biology, 1977, Volume: 91

    Topics: Animals; Antineoplastic Agents; Cytological Techniques; Evaluation Studies as Topic; Female; Ligands; Metals; Mice; Neoplasms; Platinum; Radioisotopes; Stereoisomerism; Structure-Activity Relationship

1977
Timely appraisal: ectopic (exocellular) nucleic acid as a drug target, especially in rheumatoid arthritis and certain cancers(?).
    Agents and actions, 1975, Volume: 5, Issue:5

    Topics: Arthritis, Rheumatoid; Cell Fractionation; Cyclophosphamide; Microscopy, Electron; Neoplasms; Nucleic Acids; Platinum

1975
Clinical experiences with platinum and etoposide therapy in lung cancer.
    Oncology, 1992, Volume: 49 Suppl 1

    Topics: Etoposide; Humans; Neoplasms; Platinum

1992
Workshop report from the Division of Research Grants, National Institutes of Health. Metal carcinogenesis--a Chemical Pathology Study Section Workshop.
    Cancer research, 1992, Jul-15, Volume: 52, Issue:14

    Topics: Animals; Cadmium; Chromium; Copper; DNA; DNA Damage; Humans; Massachusetts; Mutagenesis; National Institutes of Health (U.S.); Neoplasms; Nickel; Platinum; United States

1992
Characteristics of five human tumor cell lines and sublines resistant to cis-diamminedichloroplatinum(II).
    International journal of cancer, 1991, Jan-21, Volume: 47, Issue:2

    Topics: Adenocarcinoma; Breast Neoplasms; Carboplatin; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Survival; Cisplatin; DNA; Drug Resistance; Glutathione Transferase; Humans; Lung Neoplasms; Melanoma; Neoplasms; Organoplatinum Compounds; Platinum; Sulfhydryl Compounds; Tumor Cells, Cultured

1991
Continuous infusion carboplatin on a 21-day schedule: a phase I and pharmacokinetic study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1991, Volume: 9, Issue:1

    Topics: Adult; Aged; Carboplatin; DNA, Neoplasm; Drug Administration Schedule; Drug Evaluation; Female; Glomerular Filtration Rate; Humans; Infusions, Intravenous; Kidney; Leukopenia; Male; Middle Aged; Neoplasms; Platinum; Regional Blood Flow; Remission Induction

1991
Trace element analysis in body fluids by glow discharge mass spectrometry: a study of lead mobilization by the drug cis-platin.
    Biological mass spectrometry, 1991, Volume: 20, Issue:3

    Topics: Cisplatin; Humans; Lead; Mass Spectrometry; Neoplasms; Platinum; Trace Elements

1991
[Current status and prospects of the clinical chemotherapy of tumorous diseases].
    Vestnik Akademii meditsinskikh nauk SSSR, 1986, Issue:5

    Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Humans; Immunotherapy; Male; Naphthacenes; Neoplasms; Organoplatinum Compounds; Palliative Care; Platinum

1986
[Platinum and catalysts--possible effects on the environment].
    Schriftenreihe des Vereins fur Wasser-, Boden- und Lufthygiene, 1987, Volume: 74

    Topics: Air Pollutants; Catalysis; Germany, West; Humans; Maximum Allowable Concentration; Neoplasms; Platinum; Risk Factors; Vehicle Emissions

1987
Pharmacokinetics of platinum in cancer patients treated with carboplatin in combination with high-dose methotrexate.
    Pharmaceutical research, 1989, Volume: 6, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Creatinine; Female; Humans; Male; Methotrexate; Middle Aged; Neoplasms; Organoplatinum Compounds; Platinum; Spectrophotometry, Atomic; Ultrafiltration

1989
[Cisplatin (platidiam) and the prospects for using complex platinum compounds in the clinical chemotherapy of malignant tumors].
    Voprosy onkologii, 1989, Volume: 35, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Evaluation; Female; Humans; Male; Neoplasms; Organoplatinum Compounds; Platinum; Remission Induction

1989
Pharmacokinetics of cisplatin in patients receiving interleukin-2-containing treatment regimens.
    Cancer chemotherapy and pharmacology, 1989, Volume: 24, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Creatinine; Fluorouracil; Humans; Interleukin-2; Metabolic Clearance Rate; Neoplasms; Platinum

1989
Determination of cis-diamminedichloroplatinum (II) in plasma proteins and hemoglobin of cancer patients.
    Archives of toxicology, 1989, Volume: 63, Issue:5

    Topics: Adolescent; Adult; Aged; Blood Proteins; Cisplatin; Female; Hemoglobins; Humans; Male; Middle Aged; Neoplasms; Platinum

1989
Noninvasive monitoring of drug biodistribution and metabolism: studies with intraarterial Pt-195m-cisplatin in humans.
    Cancer research, 1989, Apr-01, Volume: 49, Issue:7

    Topics: Cisplatin; Female; Humans; Injections, Intra-Arterial; Male; Models, Biological; Monitoring, Physiologic; Neoplasms; Platinum; Radioisotopes; Tissue Distribution

1989
[Plasma, renal and tumor determination of total platinum during predictive tests of chemosensitivity of human tumor implants in the renal capsule in syngeneic mice].
    Pathologie-biologie, 1988, Volume: 36, Issue:10

    Topics: Animals; Cisplatin; Drug Implants; Humans; Kidney; Mice; Neoplasm Transplantation; Neoplasms; Platinum; Subrenal Capsule Assay; Tissue Distribution; Transplantation, Isogeneic

1988
A method for in vivo analysis of platinum after chemotherapy with cisplatin.
    Physics in medicine and biology, 1988, Volume: 33, Issue:7

    Topics: Cisplatin; Humans; Kidney; Male; Neoplasms; Platinum; Spectrometry, X-Ray Emission; Testicular Neoplasms

1988
Platinum concentrations in human autopsy tumor samples.
    American journal of clinical oncology, 1988, Volume: 11, Issue:2

    Topics: Autopsy; Brain Neoplasms; Cisplatin; Female; Humans; Liver Neoplasms; Male; Neoplasms; Platinum; Spectrophotometry, Atomic

1988
Pharmacokinetics of free and total platinum species after rapid and prolonged infusions of aqua (1,1-bis(aminomethyl)cyclohexane) sulfatoplatinum (II) (spiroplatin) during a phase I trial.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Cisplatin; Drug Evaluation; Female; Half-Life; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Organoplatinum Compounds; Platinum; Time Factors

1988
Methodology for the rational development of methotrexate analogs in the clinic.
    NCI monographs : a publication of the National Cancer Institute, 1987, Issue:5

    Topics: Antibiotics, Antineoplastic; Drug Evaluation; Folic Acid Antagonists; Humans; Methotrexate; Naphthacenes; Neoplasms; Platinum

1987
Kinetics of platinum in cancer patients treated with cisplatin at different doses.
    Drugs under experimental and clinical research, 1987, Volume: 13, Issue:6

    Topics: Adult; Aged; Cisplatin; Female; Half-Life; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Platinum; Protein Binding

1987
Reduced ability to clear ultrafilterable platinum with repeated courses of cisplatin.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:9

    Topics: Adult; Aged; Cisplatin; Female; Humans; Kidney Function Tests; Kinetics; Lung Neoplasms; Male; Middle Aged; Neoplasms; Platinum; Teratoma; Ultrafiltration

1986
Rapid determination of platinum by flameless atomic absorption spectrophotometry following the administration of cisplatin to cancer patients.
    Therapeutic drug monitoring, 1986, Volume: 8, Issue:3

    Topics: Cisplatin; Female; Humans; Middle Aged; Neoplasms; Platinum; Spectrophotometry, Atomic

1986
Phase I study and pharmacokinetics of intraperitoneal carboplatin.
    Cancer treatment reviews, 1985, Volume: 12 Suppl A

    Topics: Antineoplastic Agents; Carboplatin; Drug Evaluation; Humans; Kinetics; Neoplasms; Organoplatinum Compounds; Platinum

1985
Pharmacokinetics of free and total platinum species after rapid and prolonged infusions of cisplatin.
    Clinical pharmacology and therapeutics, 1986, Volume: 39, Issue:2

    Topics: Adult; Aged; Cisplatin; Drug Administration Schedule; Drug Therapy, Combination; Erythrocytes; Half-Life; Humans; Infusions, Parenteral; Kidney; Kinetics; Liver; Middle Aged; Neoplasms; Platinum; Pleural Effusion

1986
Nonlinear renal clearance of ultrafilterable platinum in patients treated with cis-dichlorodiammineplatinum (II).
    Cancer chemotherapy and pharmacology, 1985, Volume: 15, Issue:3

    Topics: Adult; Aged; Cisplatin; Female; Humans; Kidney; Kinetics; Male; Middle Aged; Neoplasms; Platinum; Ultrafiltration

1985
Trace elements that act to inhibit neoplastic growth.
    Annals of the New York Academy of Sciences, 1972, Jun-28, Volume: 199

    Topics: Animals; Arsenic; Copper; Environmental Health; Geological Phenomena; Geology; Humans; Iodine; Neoplasms; Neoplasms, Experimental; Platinum; Rats; Selenium; Trace Elements; Zinc

1972
Solid geometry versus plane geometry for 252 Cf sources.
    Physics in medicine and biology, 1972, Volume: 17, Issue:6

    Topics: Californium; Iridium; Mathematics; Neoplasms; Platinum; Radiotherapy Dosage

1972
Preliminary clinical experience with cis-diamminedichloroplatinum (II) (NSC 119875, CACP).
    Cancer, 1972, Volume: 30, Issue:6

    Topics: Amines; Anemia; Antineoplastic Agents; Audiometry; Blood Urea Nitrogen; Bone Marrow; Bone Marrow Cells; Chlorides; Dose-Response Relationship, Drug; Hearing Disorders; Humans; Kidney; Leukopenia; Neoplasm Metastasis; Neoplasms; Platinum; Thrombocytopenia; Time Factors; Uric Acid; Vomiting

1972
Some preliminary observations during the phase I clinical testing of cis-dichlorodiammineplatinum. II.
    Neoplasma, 1973, Volume: 20, Issue:2

    Topics: Adult; Amines; Breast Neoplasms; Carcinoma, Bronchogenic; Chlorides; Evaluation Studies as Topic; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasms; Platinum; Stomach Neoplasms

1973
[Other new antineoplastic chemotherapeutic agents].
    Casopis lekaru ceskych, 1972, Nov-03, Volume: 111, Issue:45

    Topics: Antineoplastic Agents; Biological Products; Cyclophosphamide; Humans; Neoplasms; Platinum

1972
[Preventive effect of platinum colloid (Sunhirai) on radiation injuries].
    Rinsho hoshasen. Clinical radiography, 1969, Volume: 14, Issue:2

    Topics: Adult; Aged; Animals; Cobalt Isotopes; Colloids; Female; Humans; Male; Mice; Middle Aged; Neoplasms; Palladium; Platinum; Radiation Injuries; Radiation-Protective Agents

1969
[Dosimetry in intratissular administration of Au-198 in granules with platinum covering].
    Meditsinskaia radiologiia, 1969, Volume: 14, Issue:9

    Topics: Drug Packaging; Gold Isotopes; Methods; Neoplasms; Platinum; Radiometry

1969