Page last updated: 2024-08-22

platinum and Hepatocellular Carcinoma

platinum has been researched along with Hepatocellular Carcinoma in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19903 (10.34)18.7374
1990's1 (3.45)18.2507
2000's4 (13.79)29.6817
2010's11 (37.93)24.3611
2020's10 (34.48)2.80

Authors

AuthorsStudies
Chan, MH; Chang, YC; Chen, CL; Chung, YL; Hsiao, M; Li, CH; Lu, CN; Wei, DH1
Bian, M; Chen, Y; Fan, R; Liu, W; Lu, Y; Xu, Z; Yang, Z1
Li, P; Li, S; Li, T; Li, X; Wu, W; Xiao, H; Xie, P; Yang, J; Yu, Y; Zhang, L; Zhang, Y; Zhao, L; Zhao, Z1
Chen, J; Chen, P; Pan, Y; Qin, P; Wang, Y; Xiao, X; Zhou, D1
Chen, SC; Lai, YH; Tung, KC1
Bilewicz, A; Chajduk, E; Majkowska-Pilip, A; Szwed, M; Wawrowicz, K; Żelechowska-Matysiak, K1
Atabi, F; Jassem, RM; Mohammadi, R; Sabokrouh, A1
Abe, K; Fujita, M; Hayashi, M; Ohira, H; Okai, K; Takahashi, A1
Gao, S; Gou, J; He, H; Tang, X; Wang, Y; Wu, R; Xue, Y; Yin, T; Zhang, Y1
Bilewicz, A; Chajduk, E; Gaweł, D; Majkowska-Pilip, A; Pieńkowski, T; Wawrowicz, K1
El-Sonbaty, S; Kandil, E; Mahmoud, M; Mansour, S; Medhat, A1
Dong, K; Huang, Y; Kang, L; Liu, C; Qu, X; Ren, J; Wang, F; Wang, Z; Zhang, Y1
Cabrera, T; Roberge, D; Valentine, K1
Aoyagi, Y; Igarashi, M; Kamimura, K; Kawai, H; Osaki, A; Suda, T; Takamura, M; Tamura, Y; Tsuchiya, A; Yamagiwa, S1
Chen, ZF; Li, YL; Liang, H; Liu, YC; Qin, QP1
Chen, X; Jiang, D; Li, Y; Liu, C; Liu, F; Liu, L; Luo, F; Pu, X; Xiang, G; Zhang, L1
Cabral, H; Kaida, S; Kataoka, K; Morikawa, S; Murayama, H; Naka, S; Tani, T; Vinh, NQ1
Du, XJ; Li, HJ; Liu, Y; Shen, S; Sun, CY; Wang, J; Xia, JX; Zhu, YH1
Bian, ZX; Cheng, GY; Chui, CH; Feng, YH; Gambari, R; Ho, CL; Lam, KH; Lam, PL; Lo, YH; Wang, QW; Wong, RS; Wong, WY1
Du, G; Fu, ZH; Jin, B; Li, J; Meng, XX; Wang, W; Zhang, SZ; Zhou, BH1
Dong, K; Dong, R; Zheng, S1
Fujiyama, S; Maeda, S; Noumaru, S; Sato, K; Shibata, J; Tanaka, M; Tomita, K1
Au-Yeung, SC; Ho, YP; Li, KK; Pang, SK; Yu, CW1
Gottesman, MM; Hamilton, TC; Johnson, SW; Pastan, I; Shen, D1
Fukushima, S; Kishimoto, S; Miyazawa, K; Takeuchi, Y1
Criado, JM; de La Fuente, A; Dominguez, MF; Izco-Basurko, I; Macias, RI; Marin, JJ; Monte, MJ; Pascual, MJ; Yajeya, J1
Dehand, J; Jordanov, J1
Fujiyama, S; Fukushima, S; Kishimoto, S; Nakano, M; Sato, T; Shibata, J1
Fujiyama, S; Fukushima, S; Hayashi, Y; Kishimoto, S; Nakano, M; Sato, T; Shibata, J1

Reviews

1 review(s) available for platinum and Hepatocellular Carcinoma

ArticleYear
Platinum-based chemotherapy in combination with PD-1/PD-L1 inhibitors: preclinical and clinical studies and mechanism of action.
    Expert opinion on drug delivery, 2021, Volume: 18, Issue:2

    Topics: Adult; Animals; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Humans; Immune Checkpoint Inhibitors; Liver Neoplasms; Lung Neoplasms; Mice; Nasopharyngeal Neoplasms; Phosphatidylinositol 3-Kinases; Platinum; Programmed Cell Death 1 Receptor; Tumor Microenvironment

2021

Trials

2 trial(s) available for platinum and Hepatocellular Carcinoma

ArticleYear
A safe and effective dose of cisplatin in hepatic arterial infusion chemotherapy for hepatocellular carcinoma.
    Cancer medicine, 2013, Volume: 2, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Hepatocellular; Cisplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Platinum; Tomography, X-Ray Computed; Treatment Outcome

2013
Phase I clinical study of a novel lipophilic platinum complex (SM-11355) in patients with hepatocellular carcinoma refractory to cisplatin/lipiodol.
    British journal of cancer, 2003, Nov-03, Volume: 89, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Hepatocellular; Contrast Media; Dose-Response Relationship, Drug; Humans; Infusions, Intra-Arterial; Iodized Oil; Liver Neoplasms; Middle Aged; Organoplatinum Compounds; Platinum

2003

Other Studies

26 other study(ies) available for platinum and Hepatocellular Carcinoma

ArticleYear
Magnetically guided theranostics: montmorillonite-based iron/platinum nanoparticles for enhancing in situ MRI contrast and hepatocellular carcinoma treatment.
    Journal of nanobiotechnology, 2021, Oct-09, Volume: 19, Issue:1

    Topics: Animals; Bentonite; Carcinoma, Hepatocellular; Cell Line, Tumor; Contrast Media; Drug Carriers; Humans; Liver Neoplasms; Magnetic Resonance Imaging; Magnetite Nanoparticles; Male; Mice; Platinum; Theranostic Nanomedicine

2021
Pt(II)-NHC Complex Induces ROS-ERS-Related DAMP Balance to Harness Immunogenic Cell Death in Hepatocellular Carcinoma.
    Journal of medicinal chemistry, 2022, 02-10, Volume: 65, Issue:3

    Topics: Animals; Antineoplastic Agents; Calreticulin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Coordination Complexes; Dendritic Cells; Endoplasmic Reticulum Stress; Humans; Imidazoles; Immunity; Immunogenic Cell Death; Liver Neoplasms; Male; Mice, Inbred C57BL; Platinum; Reactive Oxygen Species; T-Lymphocytes

2022
Abplatin
    Journal of nanobiotechnology, 2022, Jun-03, Volume: 20, Issue:1

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cisplatin; Humans; Liver Neoplasms; Platinum; Prodrugs

2022
Self-targeting platinum(IV) amphiphilic prodrug nano-assembly as radiosensitizer for synergistic and safe chemoradiotherapy of hepatocellular carcinoma.
    Biomaterials, 2022, Volume: 289

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Checkpoint Kinase 1; Chemoradiotherapy; Cisplatin; DNA; Humans; Lactose; Liver Neoplasms; Platinum; Prodrugs; Radiation-Sensitizing Agents; Reactive Oxygen Species

2022
Durable response to olaparib combined low-dose cisplatin in advanced hepatocellular carcinoma with FANCA mutation: A case report.
    Medicine, 2022, Sep-30, Volume: 101, Issue:39

    Topics: Adenosine Diphosphate Ribose; Adult; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cisplatin; Fanconi Anemia Complementation Group A Protein; Female; Humans; Liver Neoplasms; Male; Mutation; Phthalazines; Piperazines; Platinum; Poly(ADP-ribose) Polymerase Inhibitors

2022
Oxidative Status as an Attribute for Selective Antitumor Activity of Platinum-Containing Nanoparticles against Hepatocellular Carcinoma.
    International journal of molecular sciences, 2022, Nov-25, Volume: 23, Issue:23

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Metal Nanoparticles; Nanoparticles; Platinum; Reactive Oxygen Species

2022
The Anticancer Efficacy of Platinum Azidothymidin on Hepatocellular Carcinoma Via Affecting the Telomerase and the BcL-2 Genes Expression.
    Journal of gastrointestinal cancer, 2020, Volume: 51, Issue:3

    Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Hepatocellular; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Liver; Liver Neoplasms, Experimental; Male; Platinum; Proto-Oncogene Proteins c-bcl-2; Rats; Telomerase; Zidovudine

2020
Acute kidney injury after platinum-based transcatheter arterial chemoembolization and transarterial infusion chemotherapy in patients with hepatocellular carcinoma.
    Japanese journal of clinical oncology, 2020, Jan-24, Volume: 50, Issue:1

    Topics: Acute Kidney Injury; Aged; Antibiotics, Antineoplastic; Ascites; Bilirubin; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Chemotherapy, Cancer, Regional Perfusion; Diabetes Mellitus; Female; Glomerular Filtration Rate; Humans; Incidence; Liver Neoplasms; Male; Platinum; Prognosis; Retrospective Studies; Risk Factors; Serum Albumin, Human; Survival Rate; Treatment Outcome

2020
Au@Pt Core-Shell Nanoparticle Bioconjugates for the Therapy of HER2+ Breast Cancer and Hepatocellular Carcinoma. Model Studies on the Applicability of
    Molecules (Basel, Switzerland), 2021, Apr-03, Volume: 26, Issue:7

    Topics: Breast Neoplasms; Carcinoma, Hepatocellular; Cell Line, Tumor; Electrons; Female; Gold; Humans; Hydrodynamics; Imaging, Three-Dimensional; Liver Neoplasms; Metal Nanoparticles; Particle Size; Platinum; Polyethylene Glycols; Radioisotopes; Receptor, ErbB-2; Static Electricity; Trastuzumab

2021
Evaluation of the antitumor activity of platinum nanoparticles in the treatment of hepatocellular carcinoma induced in rats.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2017, Volume: 39, Issue:7

    Topics: Animals; Antioxidants; Carcinoma, Hepatocellular; Diethylnitrosamine; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Matrix Metalloproteinase 9; Metal Nanoparticles; Oxidative Stress; Platinum; Proto-Oncogene Proteins c-bcl-2; Rats; Tumor Suppressor Protein p53

2017
Nanozyme Decorated Metal-Organic Frameworks for Enhanced Photodynamic Therapy.
    ACS nano, 2018, 01-23, Volume: 12, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Catalase; Cell Line, Tumor; Female; HeLa Cells; Humans; Liver Neoplasms; Metal Nanoparticles; Metal-Organic Frameworks; Mice; Neoplasms; Photochemotherapy; Photosensitizing Agents; Platinum; Singlet Oxygen; Tumor Hypoxia

2018
Implanting metal fiducials to guide stereotactic liver radiation: McGill experience and review of current devices, techniques and complications.
    Technology in cancer research & treatment, 2014, Volume: 13, Issue:3

    Topics: Carcinoma, Hepatocellular; Cholangiocarcinoma; Female; Fiducial Markers; Gold; Humans; Liver; Liver Neoplasms; Male; Platinum; Radiography; Radiosurgery; Radiotherapy, Image-Guided; Retrospective Studies; Treatment Outcome

2014
A platinum(II) complex of liriodenine from traditional Chinese medicine (TCM): Cell cycle arrest, cell apoptosis induction and telomerase inhibition activity via G-quadruplex DNA stabilization.
    Journal of inorganic biochemistry, 2014, Volume: 137

    Topics: Apoptosis; Aporphines; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Line, Tumor; Coordination Complexes; G-Quadruplexes; Humans; Liver Neoplasms; Medicine, Chinese Traditional; Platinum; Platinum Compounds; Telomerase

2014
Ultrasensitive strategy based on PtPd nanodendrite/nano-flower-like@GO signal amplification for the detection of long non-coding RNA.
    Biosensors & bioelectronics, 2015, Dec-15, Volume: 74

    Topics: Biosensing Techniques; Carcinoma, Hepatocellular; Electrochemical Techniques; Graphite; Humans; Limit of Detection; Liver Neoplasms; Nanostructures; Palladium; Platinum; Reproducibility of Results; RNA, Long Noncoding

2015
MRI-detectable polymeric micelles incorporating platinum anticancer drugs enhance survival in an advanced hepatocellular carcinoma model.
    International journal of nanomedicine, 2015, Volume: 10

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Liver Neoplasms, Experimental; Magnetic Resonance Imaging; Micelles; Platinum; Rats

2015
Co-delivery of platinum drug and siNotch1 with micelleplex for enhanced hepatocellular carcinoma therapy.
    Biomaterials, 2015, Volume: 70

    Topics: AC133 Antigen; Animals; Antigens, CD; Carcinoma, Hepatocellular; Cell Death; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Drug Delivery Systems; Glycoproteins; Humans; Liver Neoplasms; Mice, Inbred NOD; Mice, SCID; Micelles; Nanoparticles; Neoplastic Stem Cells; Peptides; Platinum; Receptor, Notch1; RNA, Small Interfering; Xenograft Model Antitumor Assays

2015
Synthesis of platinum(II) and palladium(II) complexes with 9,9-dihexyl-4,5-diazafluorene and their in vivo antitumour activity against Hep3B xenografted mice.
    European journal of medicinal chemistry, 2016, Nov-29, Volume: 124

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Coordination Complexes; Disease Models, Animal; Enzyme Activation; Heterografts; Humans; Liver; Liver Neoplasms; Mice; Organoplatinum Compounds; Palladium; Platinum

2016
Let-7 inhibits self-renewal of hepatocellular cancer stem-like cells through regulating the epithelial-mesenchymal transition and the Wnt signaling pathway.
    BMC cancer, 2016, 11-08, Volume: 16, Issue:1

    Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Self Renewal; Cell Transformation, Neoplastic; Disease Progression; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; MicroRNAs; Neoplastic Stem Cells; Platinum; RNA Interference; Wnt Signaling Pathway; Wnt1 Protein

2016
Distinguishing Among Pediatric Hepatoblastomas, Transitional Liver Cell Tumors, and Hepatocellular Carcinomas and Using Appropriate Chemotherapy Regimens.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Volume: 35, Issue:1

    Topics: Carcinoma, Hepatocellular; Child; Doxorubicin; Hepatoblastoma; Humans; Liver Neoplasms; Platinum

2017
Anticancer activity of a series of platinum complexes integrating demethylcantharidin with isomers of 1,2-diaminocyclohexane.
    Bioorganic & medicinal chemistry letters, 2006, Mar-15, Volume: 16, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Cantharidin; Carboplatin; Carcinoma, Hepatocellular; Cell Cycle; Cisplatin; Colorectal Neoplasms; Cyclohexylamines; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Isomerism; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Platinum; Tumor Cells, Cultured

2006
Cross-resistance, cisplatin accumulation, and platinum-DNA adduct formation and removal in cisplatin-sensitive and -resistant human hepatoma cell lines.
    Experimental cell research, 1996, Jul-10, Volume: 226, Issue:1

    Topics: Carcinoma, Hepatocellular; Cisplatin; Cross-Linking Reagents; DNA; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Liver Neoplasms; Platinum; Tumor Cells, Cultured

1996
In vitro antitumor activity, intracellular accumulation, and DNA adduct formation of cis-[((1R,2R)-1,2-cyclohexanediamine-N,N')bis(myristato)] platinum (II) suspended in lipiodol.
    Japanese journal of cancer research : Gann, 2000, Volume: 91, Issue:1

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Division; Cisplatin; DNA Adducts; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Iodized Oil; Organoplatinum Compounds; Platinum; Rats; Solvents; Time Factors; Tumor Cells, Cultured

2000
Low in vivo toxicity of a novel cisplatin-ursodeoxycholic derivative (Bamet-UD2) with enhanced cytostatic activity versus liver tumors.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:3

    Topics: Animals; Antineoplastic Agents; Bone Marrow; Carcinoma, Hepatocellular; Cisplatin; Disease Models, Animal; Drug Evaluation, Preclinical; Injections, Intraperitoneal; Kidney; Kidney Function Tests; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Nude; Myocardium; Neoplasm Transplantation; Neural Conduction; Organoplatinum Compounds; Platinum; Rats; Rats, Wistar; Sciatic Nerve; Survival Rate; Tissue Distribution; Tumor Cells, Cultured; Ursodeoxycholic Acid

2001
Anti-tumour activity of heavy transition metal complexes against hepatoma cells.
    Chemico-biological interactions, 1975, Volume: 11, Issue:6

    Topics: Animals; Carcinoma, Hepatocellular; Liver Neoplasms; Neoplasms, Experimental; Organometallic Compounds; Palladium; Platinum; Rats; Rhodium; Structure-Activity Relationship; Sulfhydryl Compounds

1975
Hepatic arterial injection chemotherapy with cisplatin suspended in an oily lymphographic agent for hepatocellular carcinoma.
    Cancer, 1989, Oct-15, Volume: 64, Issue:8

    Topics: Adult; Aged; alpha-Fetoproteins; Carcinoma, Hepatocellular; Cause of Death; Cisplatin; Female; Follow-Up Studies; Hepatic Artery; Humans; Injections, Intra-Arterial; Iodized Oil; Liver Neoplasms; Male; Middle Aged; Platinum; Suspensions

1989
[Intra-arterial injection of cisplatin suspension in Lipiodol (LPS) in the treatment of hepatocellular carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:8 Pt 2

    Topics: Animals; Carcinoma, Hepatocellular; Cisplatin; Gastric Mucosa; Humans; Injections, Intra-Arterial; Iodized Oil; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Platinum; Rabbits; Remission Induction; Suspensions; Tissue Distribution

1989