platinum has been researched along with Carcinoma, Non-Small Cell Lung in 394 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (1.02) | 18.7374 |
| 1990's | 10 (2.54) | 18.2507 |
| 2000's | 37 (9.39) | 29.6817 |
| 2010's | 187 (47.46) | 24.3611 |
| 2020's | 156 (39.59) | 2.80 |
| Authors | Studies |
|---|---|
| Avancini, A; Belluomini, L; Casali, M; Dionisi, V; Mazzarotto, R; Menis, J; Milella, M; Palmerio, S; Pilotto, S; Riva, ST; Vincenzi, S | 1 |
| Bunn, V; Felip, E; Garcia Campelo, MR; Griffin, C; Jänne, PA; Jin, S; Kim, SW; Kim, TM; Lin, HM; Lin, J; Mehta, M; Mekhail, T; Nguyen, D; Ramalingam, SS; Riely, GJ; Vincent, S; Yang, JC; Zhou, C | 1 |
| Jin, H; Kim, EH; Lee, JY; Park, SB; Yoon, JH; Yoon, SW | 1 |
| Fujishita, T; Ito, K; Matsubara, T; Okamoto, T; Seto, T; Takamori, S; Toyozawa, R; Yamaguchi, M | 1 |
| Kim, HJ; Kim, JS; Lee, M; Lim, JH; Park, MH; Ryu, JS; Ryu, WK | 1 |
| Chen, J; Cheng, Y; Gao, B; Li, X; Liu, D; Liu, X; Zhang, M; Zhou, H | 1 |
| Bajor, DL; Biswas, T; Bruno, DS; Cao, S; Dowlati, A; Fu, P; Gerson, SL; Kunos, CA; Machtay, M; Malik, S; Oleinick, NL; Patel, M; Pink, JJ | 1 |
| Amano, Y; Hamaguchi, M; Hamaguchi, S; Hata, K; Hotta, T; Isobe, T; Kurimoto, N; Mitarai, Y; Nagao, T; Nakao, M; Nakashima, K; Okimoto, T; Okuno, T; Tanaka, S; Tanino, A; Tsubata, Y | 1 |
| Fukuda, N; Hara, Y; Horita, N; Kaneko, A; Kaneko, T; Kobayashi, N; Namkoong, H; Somekawa, K; Tagami, Y; Watanabe, K | 1 |
| Blais, N; Bradbury, PA; Dancey, J; Ding, K; Goss, GD; Hiltz, A; Hughes, BGM; Hwang, DM; Joubert, P; Joy, AA; Kulkarni, S; Laurie, SA; Lee, C; Leighl, NB; Mates, M; Rana, P; Stockler, M; Tsao, MS; Underhill, C; Vera-Badillo, F; Yadav, SK | 1 |
| Ando, M; Hakozaki, T; Horinouchi, H; Kataoka, T; Miura, S; Nomura, S; Ohe, Y; Okamoto, I; Sekino, Y; Shiraishi, Y; Tanaka, K | 1 |
| But-Hadzic, J; Ciric, E; Jelercic, S; Stanic, K; Vodusek, AL; Vrankar, M | 1 |
| Garon, EB; Kim, JS; Peterson, P; Rizzo, MT | 1 |
| Chen, Y; Liu, J; Lv, J; Pan, C; Pan, G; Yang, Y; Zhang, C | 1 |
| Chen, TT; Cunanan, K; Das, M; Gardner, RM; Neal, JW; Padda, SK; Piotrowska, Z; Piper-Vallillo, AJ; Ramchandran, K; Sequist, LV; Wakelee, HA; White, MN | 1 |
| Enomoto, N; Fujisawa, T; Furuhashi, K; Hozumi, H; Inoue, Y; Inui, N; Karayama, M; Nakamura, Y; Suda, T; Suzuki, Y; Yasui, H | 1 |
| Ainsworth, B; Ammar, A; Ellis, PA; Pakozdi, T; Ramathal, CY; Riley-Gillis, B; Stolzenburg, LR; Wilsbacher, JL | 1 |
| Bar, J; Daher, S; Dudnik, E; Holtzman, L; Keren, S; Moskovitz, M; Nechushtan, H; Reinhorn, D; Rottenberg, Y; Rovitzky, Y; Shochat, T; Urban, D; Wollner, M | 1 |
| Aggarwal, C; Ciunci, C; Cohen, RB; Hwang, WT; Langer, CJ; Mamtani, R; Marmarelis, ME; Singh, A; Yang, YX | 1 |
| Akinboro, O; Beaver, JA; Bi, Y; Bulatao, I; Cheng, J; Chuk, MK; Cohen, R; Donoghue, M; Fiero, MH; Fourie Zirkelbach, J; Fu, W; Gong, Y; He, K; Helms, WS; Herz, J; Jafri, S; Kalavar, S; Larkins, E; Li, H; Liu, J; Mathieu, LN; Mishra-Kalyani, PS; Osborn, BL; Pai-Scherf, LH; Pazdur, R; Ren, Y; Sickafuse, S; Singh, H; Wang, M; Xu, Y; Zhao, H | 1 |
| Almeida, SB; Domingues, TD; Fernandes, G; Honório, M; Santos, CLD; Silva, S; Simões, P; Spencer, AS | 1 |
| Cai, L; Chen, C; Deng, H; Li, S; Lin, X; Liu, M; Qin, Y; Qiu, G; Xie, X; Xie, Z; Yang, Y; Zhou, C | 1 |
| Ge, M; Li, Q; Liang, X; Qi, H; Shi, X; Wang, T; Wang, Y; Zhan, Q; Zhang, L; Zhang, W; Zhong, M | 1 |
| Chang, JH; Chang, TH; Chen, WT; Chien, LN; Chou, YT; Chung, CL; Hong, SY; Hsiao, SH; Lin, SE | 1 |
| Tian, H; Tian, Y; Yu, J; Zhai, X; Zhu, H | 1 |
| Chen, J; Hong, WX; Liu, JS; Liu, ZQ; Mo, JL; Xiao, Q; Yin, JY | 1 |
| Guo, D; Huang, X; Li, H; Liu, T; Miao, S; Shen, M; Wang, M; Wang, Q; Wu, J; Xiao, Z; Zhao, L | 1 |
| Date, H; Inoue, A; Kawaguchi, T; Kenmotsu, H; Kiura, K; Miyaoka, E; Miyawaki, E; Okamoto, I; Sekine, I; Shintani, Y; Shukuya, T; Takahashi, K; Takayama, K; Yamamoto, N; Yoshino, I | 1 |
| An, T; Chen, H; Chi, Y; Huang, D; Jia, B; Li, J; Lin, G; Wang, J; Wang, Y; Wang, Z; Wu, M; Yang, X; Zhai, X; Zhao, J; Zhuo, M | 1 |
| Huang, Z; Xiong, G | 1 |
| Cheong, TF; Chiang, KY; Ho, JCM; Ip, MSM; Kwok, WC; Lam, DCL; Tam, TCC | 1 |
| Abu-Hejleh, T; Allen, BG; Bellizzi, AM; Bodeker, KL; Bossler, AD; Buatti, JM; Buettner, GR; Byrne, MM; Cullen, JJ; Fath, MA; Furqan, M; Hartwig, SM; Henrich, JB; Houtman, JC; Ivanovic, M; Mani, H; Monga, V; Mott, SL; Petronek, M; Pulliam, CF; Smith, BJ; Spitz, DR; Stephens, LM; Varga, SM; Wagner, BA; Zeitler, W; Zhang, J | 1 |
| Bai, KJ; Chang, JH; Chen, HY; Chu, CY; Hsu, YC; Huang, SH; Kuo, LN; Liu, EH; Wang, SY; Yu, MC | 1 |
| Chin, V; Daneshvar, D; Karikios, D; Lim, J; McCloy, R; Murphy, A; Nagrial, A; O'Toole, S; Steinmann, AM; Wong, S | 1 |
| Backenroth, D; Bauml, JM; Bazhenova, L; Bhattacharya, A; Gadgeel, SM; Girard, N; Li, T; Mahadevia, P; Minchom, A; Ou, SI; Trigo, J; Viteri, S | 1 |
| Bozorgmehr, F; Brueckl, WM; Budczies, J; Christopoulos, P; Dintner, S; Eichhorn, F; Faehling, M; Falkenstern-Ge, RF; Frost, N; Griesinger, F; Grohé, C; Hackanson, B; Hong, JL; Janning, M; Kauffmann-Guerrero, D; Kazdal, D; Kirchner, M; Kluck, K; Kollmeier, J; Kuon, J; Kurz, S; Lin, HM; Loges, S; Lüders, H; Misch, D; Reck, M; Roeper, J; Saalfeld, FC; Schulz, C; Shah, R; Stenzinger, A; Sticht, F; Szewczyk, M; Thomas, M; Tufman, A; Wermke, M; Wesseler, C | 1 |
| Gu, X; Lou, G; Shao, L; Shi, Z; Song, Z; Wang, W; Zhang, Y | 1 |
| Ali, WA; Fang, WF; Gan, JD; Huang, YH; Liao, J; Lv, Y; Pang, LL; Zhang, L | 1 |
| Aa, L; Gao, J; Jiang, W; Li, W; Liang, J; Sun, W; Wang, H; Wang, L; Zhou, W | 1 |
| Gu, Q; Li, S | 1 |
| Chen, Z; Ke, Y; Lin, Z; Lu, Z; Rao, D; Sun, T; Wu, S; Ye, M; Zhang, D; Zhang, X | 1 |
| Carlisle, J; Chen, Z; Dhodapkar, M; Leal, T; Liu, Y; Osta, BE; Owonikoko, T; Pakkala, S; Ramalingam, S; Steuer, C | 1 |
| Rodriguez, E; Santos, ES | 1 |
| Fathallah, H; Karim, NA; Morris, JC; Pathrose, P; Perry, A; Starnes, SL; Ullah, A; Wang, J | 1 |
| Cang, S; Chen, G; Fang, J; Han, B; Lin, Y; Mei, X; Stefaniak, V; Sun, L; Wang, S; Wang, Z; Yang, Y; Yang, Z; Yu, Q; Zhang, L; Zhang, W | 1 |
| Bessho, A; Furuya, N; Goto, Y; Harada, T; Kawashima, Y; Misumi, T; Miura, S; Nakahara, Y; Nakamura, Y; Naoki, K; Okamoto, H; Seike, M; Shimokawa, T; Shiraishi, Y; Takiguchi, Y; Tanaka, H; Taniguchi, Y; Tokito, T; Uchiyama, A | 1 |
| Dvorkin, M; Gao, B; Gessner, C; Giorgadze, D; Gogishvili, M; Gullo, G; Kalinka, E; Kaul, M; Laktionov, K; Li, S; Lowy, I; Makharadze, T; McGuire, K; Melkadze, T; Moreno-Jaime, B; Nechaeva, M; Nemsadze, G; Paccaly, A; Passalacqua, R; Penkov, K; Quek, RGW; Rietschel, P; Rozhkova, I; Seebach, F; Weinreich, DM; Yancopoulos, GD | 1 |
| Deng, W; Deng, Y; Duan, Z; Liao, R; Luo, J | 1 |
| Cao, L; Fan, Y; Fang, J; He, J; Hu, J; Liu, W; Liu, Y; Lu, S; Shi, J; Wang, Z; Xia, J; Yi, J; Zhou, J | 1 |
| Cui, S; Li, L; Lu, X; Xiao, M; Xue, P; Yu, T; Zhang, G; Zhang, H; Zhang, L | 1 |
| Liu, X; Shi, Y; Xu, J; Yang, S | 1 |
| Luo, T; Ma, H; Ren, X; Yu, S; Zhou, M | 1 |
| Choi, CM; Choi, J; Jang, TW; Kim, EY; Lee, JE; Lee, KY; Lee, SH; Lee, SY; Oh, IJ; Park, DW; Park, SH | 1 |
| Abbie, E; Boyne, DJ; Brenner, DR; Cheung, WY; Eaton, K; Elia-Pacitti, J; Ewara, EM; Gogna, P; Hu, LXY; Jarada, TN; O'Sullivan, DE; Pabani, A; Rose, JB; Yusuf, A | 1 |
| Bondarenko, I; Brady, KJS; Chen, CI; Cicin, I; Gogishvili, M; Gullo, G; Gümüş, M; Harnett, J; Ivanescu, C; Kilickap, S; Konidaris, G; Li, S; Mastey, V; Naumann, U; Özgüroğlu, M; Reaney, M; Rietschel, P; Sasane, M; Sezer, A; Turk, HM | 1 |
| Gao, Y; Li, B; Liu, Y; Wang, Y; Zhang, T; Zhang, Z; Zhao, C | 1 |
| Bruns, CJ; Hekmat, K | 1 |
| Hou, H; Jiang, M; Li, T; Sun, D; Wang, Y; Zhang, C; Zhang, X; Zhou, N; Zhu, J | 1 |
| Hua, X; Liu, H; Lv, T; Song, Y; Wu, X; Xu, K; Zhan, P; Zhang, F | 1 |
| Baglivo, S; Bellezza, G; Bonaiti, A; Colafigli, C; Di Girolamo, B; Ludovini, V; Mandarano, M; Matocci, R; Metelli, N; Metro, G; Roila, F | 1 |
| Chen, C; Chen, N; Chen, R; Chen, X; Cong, X; Cui, G; Cui, J; Jia, L; Li, W; Liu, Z; Lu, J; Ma, K; Niu, C; Song, W; Wang, N; Wang, X; Xu, Y; Yang, L; Zhao, Y | 1 |
| Aggarwal, H; Muehlenbein, CE; Ndirangu, K; Thom, H; Tongbram, V; Winfree, KB; Zhu, E | 1 |
| Brouwer, J; de Jong, C; Deneer, VHM; Egberts, TCG; Herder, GJM; Ten Heuvel, A; van der Meer, FS; van Haarlem, SWA; van Lindert, ASR | 1 |
| Bennouna, J; Bodot, L; Boudoussier, A; Chatellier, T; Curcio, H; Demontrond, P; Dumenil, C; Gourraud, PA; Guardiolle, V; Hiret, S; Hulo, P; Mayenga, M; Mazieres, J; Pons-Tostivint, E; Porte, M; Rabeau, A; Veillon, R | 1 |
| Azuma, K; Fujimoto, D; Hasegawa, K; Hayakawa, D; Hayashi, H; Iwama, E; Kato, T; Nakagawa, K; Nakamura, A; Nosaki, K; Oki, M; Shimokawa, M; Tachihara, M; Takahashi, T; Takeda, M; Tanaka, H; Watanabe, Y; Yamaguchi, K; Yamamoto, N; Yamamoto, S | 1 |
| Frances, N; Geiger, K; Hartung, N; Henrich, A; Holdenrieder, S; Huisinga, W; Joerger, M; Kloft, C; Nassar, YM; Ojara, FW | 1 |
| Bigay-Game, L; Bylicki, O; Castera, M; Chouaid, C; Clarisse, B; Daniel, C; Decroisette, C; Doubre, H; Geier, M; Greillier, L; Grellard, JM; Guisier, F; Martins-Lavinas, PH; Monnet, I; Moreau, D; Peloni, JM; Radj, G; Ricordel, C; Subtil, F; Swalduz, A; Toffart, AC; Tomasini, P | 1 |
| Aldea, M; Boudier, B | 1 |
| Batista de Carvalho, ALM; Batista de Carvalho, LAE; Laginha, RC; Marques, J; Marques, MPM; Martins, CB; Santos, IP; Silva, JD | 1 |
| Balbach, ML; Bestvina, C; Camidge, DR; Hsu, R; Iams, WT; Kim, C; Leal, T; Marmarelis, ME; Mehta, K; Nieva, J; Patil, T; Phillips, S; Robinson, MA; Sacher, A; Sackstein, PE; Sethakorn, N; Velcheti, V; Wang, X | 1 |
| Carbone, DP; Furuya, N; He, K | 1 |
| Arai, D; Ito, K; Kaira, K; Kajiwara, T; Kobayashi, K; Kodama, H; Miura, K; Miyanaga, A; Mizutani, H; Mori, K; Nakamura, A; Ninomiya, T; Oba, T; Tamiya, M; Yamaguchi, O; Yanagitani, N | 1 |
| Bu, X; Cao, ZR; Duan, YF; Huang, W; Li, L; Liu, RY; Liu, TY; Luo, C; Yang, MJ; Yuan, XX; Yue, X | 1 |
| Beaver, JA; Ghosh, S; Goldberg, KB; Jafri, S; Kalavar, S; Larkins, E; Mathieu, LN; Mishra-Kalyani, PS; Pazdur, R; Singh, H; Sinha, AK | 1 |
| Chen, X; Cui, JW; Ding, X; Han, FJ; He, H; Li, FQ; Li, WQ; Li, ZZ; Niu, C; Qian, L; Tian, HM; Wang, HY; Xu, JT | 1 |
| Atagi, S; Endo, T; Fujita, Y; Kanazu, M; Kita, T; Mizuki, F; Mori, M; Motegi, M; Okano, Y; Saito, R; Shimokawa, M; Sukoh, N; Takata, S; Takenoyama, M; Tamura, A | 1 |
| Hong, JL; Jin, S; Lin, HM; Lin, J; Mehta, M; Neal, JW; Nguyen, D; Ou, SI; Yin, Y; Zhang, P | 1 |
| Akinboro, O; Amatya, A; Beaver, JA; Bi, Y; Drezner, N; Fourie-Zirkelbach, J; Korsah, K; Larkins, E; Mixter, B; Pazdur, R; Runyan, J; Singh, H; Tang, S; Zhao, M | 1 |
| Dvorkin, M; Gessner, C; Giorgadze, D; Gogishvili, M; Gullo, G; Ivanescu, C; Kalinka, E; Konidaris, G; Laktionov, K; Makharadze, T; Melkadze, T; Moreno-Jaime, B; Nechaeva, M; Nemsadze, G; Passalacqua, R; Penkov, K; Quek, RGW; Rietschel, P; Rozhkova, I | 1 |
| Bleckmann, A; Frost, N; Griesinger, F; Grohé, C; Janning, M; Kollmeier, J; Reck, M; Reinmuth, N; Sebastian, M; Thomas, M | 1 |
| Beebe, KD; Conroy, JM; Davison, JM; Eisner, JR; Farhangfar, C; Farhangfar, F; Guo, Y; Hayes, DN; Mayhew, GM; Milburn, MV; Mileham, KF; Shibata, Y; Uronis, JM | 1 |
| Chen, J; Deng, C; Deng, X; Huang, X; Li, H; Miao, S; Mu, L; Wang, Q; Wu, J; Xiao, Z; Yang, S | 1 |
| Chao, HS; Chen, YM; Chiang, CL; Hsiao, TH; Huang, HC; Liao, YT; Luo, YH; Shen, CI; Sun, RL; Tseng, YH; Wang, LC; Yeh, YC | 1 |
| Atsumi, K; Hirose, T; Hisakane, K; Nishijima, N; Okano, T; Seike, M; Takahashi, S; Taniuchi, N; Tozuka, T | 1 |
| Fan, Y; Fang, J; Kang, M; Li, W; Li, X; Liu, Q; Ma, Z; Wang, J; Wang, N; Xie, Q; Xiong, A; Xu, M; Xu, T; Zhi, L; Zhou, C; Zhuang, W | 1 |
| Biggane, AM; Califano, R; Cappuzzo, F; Connors, M; Cortinovis, D; Han, B; Höglander, E; Hu, Y; Huang, D; Kowalski, D; Le, AT; Lee, SM; Liu, G; Mak, MP; Morris, S; Palmero, R; Peters, S; Prabhash, K; Reck, M; Reyes Contreras, J; Rittmeyer, A; Schulz, C; Szczesna, A; Talbot, T; Vicente, D; Vollan, HK | 1 |
| O'Sullivan, H; Popat, S | 1 |
| Fujita, A; Fushimi, K; Iwai, C; Jo, T; Konishi, T; Matsui, H; Michihata, N; Yasunaga, H | 1 |
| Hayashi, H; Kasahara-Kiritani, M; Nishio, M; Takahashi, M; Tsuchiya, H | 1 |
| Goto, Y; Gyotoku, H; Harada, D; Kogure, Y; Murakami, S; Ninomiya, K; Nomura, S; Okamoto, H; Okishio, K; Okuma, Y | 1 |
| Alessi, JV; Arbour, KC; Arcila, ME; Awad, MM; Baine, MK; Egger, JV; Elkrief, A; Fei, T; Hellmann, MD; Kalvin, HL; Kris, MG; Ladanyi, M; Lamberti, G; Lito, P; Plodkowski, A; Riccuiti, B; Riely, GJ; Rizvi, H; Rudin, CM; Schoenfeld, AJ; Thummalapalli, R | 1 |
| Chang, Y; Chen, C; Hu, F; Huang, C; Huang, H; Jin, H; Jin, R; Jin, Z; Ma, Y; Wu, S; Xie, Q; Xue, Z; Zhao, L; Zheng, M | 1 |
| Akamatsu, H; Hida, T; Inui, N; Kang, JH; Kim, HR; Lee, JS; Lee, KH; Nakagawa, K; Nishio, M; Ohe, Y; Sugawara, S; Takahashi, S; Tamura, T; Tanaka, H; Yamamoto, N; Yang, CT; Yoshida, T; Yu, CJ | 1 |
| Besse, B; Bironzo, P; Chih-Hsin Yang, J; Dong, Q; Fan, PD; Felip, E; Goto, Y; Hayashi, H; Jänne, PA; John, T; Johnson, ML; Kao, S; Kim, DW; Kozuki, T; Lee, SH; Massarelli, E; Patel, J; Patel, P; Paz-Ares, L; Reck, M; Reckamp, KL; Sellami, D; Shrestha, P; Smit, E; Sporchia, A; Sternberg, DW; Wu, YL; Yoh, K; Yu, HA | 1 |
| Choi, CM; Ji, W; Kim, J; Lee, JC | 1 |
| Aiba, T; Domeki, Y; Kawana, S; Kawashima, Y; Kimura, Y; Nakamura, A; Sugawara, S; Sugisaka, J; Toi, Y; Yamanda, S | 1 |
| Patel, JD; Patel, S | 1 |
| Jiang, Y; Li, J; Tang, W; Xi, J; Zhao, M; Zheng, X | 1 |
| Botticelli, A; Brambilla, M; Cappuzzo, F; Cecere, FL; Ciliberto, G; Cortesi, E; Di Civita, MA; Facciolo, F; Forde, PM; Gallina, FT; Gelibter, AJ; Giusti, R; Landi, L; Liu, SV; Marinelli, D; Melis, E; Nisticò, P; Novello, S; Occhipinti, M; Pannunzio, S; Porciello, N; Roberto, M; Santini, D; Tajè, R; Torchia, A; Verrico, M | 1 |
| Chisaki, Y; Minamide, J; Nakano, H; Yano, Y | 1 |
| Gu, W; He, M; Li, Z; Zhuang, M; Zhuang, W | 1 |
| Cho, BC; Girard, N; Kim, TM; Kleinman, NJ; Lim, CTK; Low, GKM; Murota, M; Yang, Y; Yu, DY; Zhuo, J | 1 |
| García-Pardo, M; Mezquita, L | 1 |
| Ben, XS; Dong, S; Jiang, BY; Li, HR; Liao, RQ; Lin, JT; Liu, K; Liu, SM; Liu, SY; Nie, Q; Qiao, GB; Tu, HY; Wang, BC; Wang, Q; Wu, W; Wu, YL; Yan, HH; Yan, LX; Yang, JJ; Yang, XN; Zhong, WZ; Zhou, Q | 1 |
| Edwards, A; Falk, S; Hackshaw, A; Hatton, M; Jones, R; Lal, R; Lee, SM; Lewanski, C; Ngai, Y; Rudd, R; Skailes, G; Toy, E; Upadhyay, S; Woll, PJ | 1 |
| Chang, MC; Chiu, CH; Chou, PH; Lin, HH; Liu, CL; Ma, HL; Wang, JP; Wang, ST | 1 |
| Hamburger, T; Kadouri, L; Lipson, D; Nechushtan, H; Peretz, T; Rottenberg, Y; Zick, A | 1 |
| Chen, C; Chen, T; Fu, S; He, LN; Hong, S; Li, H; Lin, Z; Wang, Y; Zhang, L; Zhang, X; Zhou, Y | 1 |
| Ma, F; Peng, L; Peng, Y; Tan, C; Wan, X; Yi, L; Zeng, X | 1 |
| Ilonen, I; Järvinen, T; Koli, K; Lauri, H; Lemström, K; Myllärniemi, M; Ollila, H; Paajanen, J; Räsänen, J; Ritvos, O; Rouvinen, E; Sutinen, E | 1 |
| He, Z; Li, Y; Liu, Y; Niu, Y; Shi, H; Xu, M; Xu, Q; Zhang, Y; Zhu, J | 1 |
| Arriola, E; Bellosillo, B; Carcereny, E; Chaib, I; Clavé, S; Dalmases, A; Gibert, J; Hardy-Werbin, M; Longarón, R; Morán, T; Piquer, G; Rocha, P; Salido, M; Taus, Á | 1 |
| Feng, FC; Gu, C; Han, D; He, HL; Peng, WP; Wang, ZC; Xu, Y; Zhou, XM | 1 |
| Ishiki, H; Kiuchi, D; Kubo, E; Satomi, E; Shimizu, M; Tanaka, T; Yokota, S | 1 |
| Chen, CY; Chen, KY; Shih, JY; Yu, CJ | 1 |
| Bradford, DS; Crane, J; Deal, AM; Irvin, W; Lee, C; Morgensztern, D; Muss, HB; Pecot, C; Pennell, N; Socinski, M; Stevenson, JP; Stinchcombe, T; Villaruz, LC; Weiss, JM; West, HJ | 1 |
| Alexandris, E; Brustugun, OT; Cuyun Carter, G; Gans, S; Garon, EB; Gautschi, O; Iglesias Docampo, L; Kalofonos, H; Kim, JH; Lee, P; Orlov, SV; Oton, AB; Pérol, M; Reck, M; Scagliotti, GV; Socinski, MA; Stefaniak, VJ; Thomas, M; Wolff, K; Zimmermann, AH | 1 |
| Chang, GC; Chen, YM; Chih-Hsin Yang, J; Chiu, CH; Chong, IW; Ho, CC; Hsia, TC; Hung, JY; Lin, MC; Su, WC; Wang, CC; Wu, SY; Yang, TY; Yu, CJ | 1 |
| Bas, T; Bischoff, HG; Boyer, M; Cheng, SY; Clingan, P; Dómine, M; Esteban, E; Felip, E; Gadgeel, S; Garassino, MC; Garon, EB; Gray, JE; Grossi, F; Hochmair, MJ; Hui, R; Jennens, RR; Kurata, T; Novello, S; Peled, N; Pietanza, MC; Powell, SF; Reck, M; Rodríguez-Abreu, D; Rubio-Viqueira, B; Speranza, G; Yang, J | 1 |
| Arriola, E; Cui, ZL; Garon, EB; Levy, B; Mekhail, T; Molife, C; Pérol, M; Winfree, KB | 1 |
| Bai, W; Bepler, G; Caruso, JA; Chen, W; Heyza, J; Hu, C; Hu, CL; Jang, H; Lou, Z; Malysa, A; Moses, N; Patrick, S; Polin, L; Stemmer, P; Wang, C; Xiang, S; Zhang, M; Zhang, XM | 1 |
| Liu, L; Liu, Y; Mi, X; Shao, M; Wang, J | 1 |
| Chu, TQ; Han, BH; Lou, YQ; Xu, JL; Zhong, H; Zhong, RB | 1 |
| Gao, RK; Hou, W; Li, HZ; Li, J; Zhang, Y; Zhu, GH | 1 |
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| Chen, X; Gong, Y; He, J; Xia, J; Zhu, N | 1 |
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| Alexandris, E; Arrieta, O; Bidoli, P; Cappuzzo, F; Ciuleanu, TE; Czyzewicz, G; Dakhil, S; Gans, S; Garon, EB; Goksel, T; Gorbunova, V; Grigorescu, A; Karaseva, N; Kim, JH; Kowalyszyn, RD; Lewanski, CR; Orlov, SV; Park, K; Pérol, M; Pikiel, J; Prabhash, K; Reck, M; Sashegyi, A; Syrigos, KN; Thomas, M; Yurasov, S | 1 |
| Li, L; Wan, C; Wen, FQ | 1 |
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| Mellema, WW; Postmus, PE; Smit, EF; van der Hoek, D | 1 |
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| Georgoulias, V; Giagkas, G; Ioannidis, G; Koutsopoulos, A; Lagoudaki, E; Mavroudis, D; Papadaki, C; Sfakianaki, M; Souglakos, J; Trypaki, M; Tsakalaki, E; Voutsina, A | 1 |
| Choi, CM; Chung, JH; Hwang, YI; Jang, SH; Jo, J; Kim, CH; Kim, HR; Kim, SS; Kim, WS; Koh, JS; Lee, JC; Park, TS; Yoon, HI | 1 |
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| Altinok, T; Aribas, O; Artac, M; Boruban, MC; Bozcuk, H; Dede, I; Demirkazik, A; Geredeli, C; Guler, T; Inal, A; Karaagac, M; Koral, L; Yildirim, S; Zamani, AG | 1 |
| Agelaki, S; Georgoulias, V; Kalikaki, A; Kotsakis, A; Koutsopoulos, A; Mavroudis, D; Papadaki, C; Sfakianaki, M; Souglakos, J; Voutsina, A; Xyrafas, A; Yachnakis, E | 1 |
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| Liu, Y; Wang, L; Yang, P; Zhou, Y | 1 |
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| Ahn, MJ; Cho, BC; Jang, JS; Jung, I; Kim, DW; Kim, HR; Kim, JH; Kim, SW; Lee, DH; Lee, KH; Sun, JM | 1 |
| Chen, L; Ding, J; Li, J; Li, N; Ma, H; Sun, Y; Wang, C; Xiao, Z; Yao, X | 1 |
| Postel-Vinay, S; Soria, JC | 1 |
| Ahn, M-J; Akamatsu, H; Garassino, MC; Ghiorghiu, S; He, Y; Kim, HR; Lee, CK; Mann, H; Marotti, M; Mok, TS; Papadimitrakopoulou, VA; Ramalingam, SS; Sebastian, M; Shepherd, FA; Templeton, A; Theelen, WS; Wu, Y-L | 1 |
| Broggini, M; Caiola, E; Ceppi, L; Damia, G; Ganzinelli, M; Garassino, MC; Guffanti, F; Marabese, M; Piva, S; Rulli, E | 1 |
| Li, B; Li, W; Ma, K; Su, K; Wang, C; Xu, W | 1 |
| Berghmans, T; Biesma, B; Chittazhathu Kurian Kuruvilla, Y; Ciardiello, F; Coate, L; Cobo Dols, M; Collado Martin, R; Cuffe, S; Curioni-Fontecedro, A; Dafni, U; de Hosson, S; Garde Noguera, J; Gasca-Ruchti, A; Gautschi, O; Gregorc, V; Groen, HJM; Horgan, A; Insa, A; Juan Vidal, Ó; Kassapian, M; Láng, I; López Martín, A; Mark, MT; Massutí, B; Meldgaard, P; Novello, S; Palmero Sanchez, R; Peralta, S; Peters, S; Pieterman, R; Ponce Aix, S; Rauch, D; Smit, EF; Stahel, RA; Summers, Y; Torri, V; Tsourti, Z; van den Berg, PM; van Heemst, R; van Henten, AMJ; Villa Guzmán, JC; Zielinski, CC | 1 |
| Hutchinson, L | 1 |
| Barsanti-Innes, B; Hey, SP; Kimmelman, J | 1 |
| Antonio, BS; Bunn, PA; Ciuleanu, T; Denne, J; Iturria, N; John, W; Paz-Ares, LG; Scagliotti, GV; Zimmermann, A | 1 |
| Zhang, J; Zhang, Y | 1 |
| Cho, JH; Jang, TW; Kim, CS; Kim, HJ; Kim, HT; Kim, SK; Kim, YH; Kwak, SM; Lee, JE; Ryu, JS; Shin, ES; Yoo, YK; Yun, MH | 1 |
| Dickgreber, NJ; Fink, TH; Hossain, AM; Latz, JE; Musib, LC; Thomas, M | 1 |
| Chu, Z; Gao, G; Huang, R; Jiang, J; Liang, X; Zhan, Q; Zhou, X | 1 |
| Choi, JH; Choi, YW; Han, JH; Hwang, SC; Jeong, SH; Jung, JH; Kang, SY; Kim, JH; Lee, HW; Oh, YT; Park, KJ; Sheen, SS | 1 |
| Altug, S; Chu, DT; Cok, G; Damyanov, D; Hall, B; Hsu, HK; Kim, SW; Patil, S; Roubec, J; West, T | 1 |
| Crysandt, M; Esser, A; Jost, E; Osieka, R; von Hobe, S; Wilop, S | 1 |
| Hu, WJ; Liu, BR; Liu, XZ; Qian, XP; Shi, MQ; Wei, J; Zou, ZY | 1 |
| Lu, S; Yu, YF; Zhang, YF | 1 |
| Chen, ZW; Lu, S; Zhang, YF | 1 |
| Gupta, A; Mittal, B; Natu, SM; Negi, MP; Prasad, R; Srivastava, AN; Srivastava, S | 1 |
| Cao, Y; Chen, B; Cheng, H; Cheng, L; Feng, J; Li, F; Sun, N; Sun, X | 1 |
| Agelaki, S; Agelidou, A; Chandrinos, V; Georgoulias, V; Gioulbasanis, I; Hatzidaki, D; Karampeazis, A; Kotsakis, A; Lerikou, M; Papakotoulas, P; Polyzos, A; Tsiafaki, X; Ziras, N | 1 |
| Gou, Y; Guo, H; Jiang, L; Tian, J; Yang, K; Yang, Q; Zhang, L; Zhang, R | 1 |
| Endo, M; Naito, T; Takahashi, T; Tamiya, A; Yamamoto, N | 1 |
| Eguchi, K; Ichinose, Y; Kishi, K; Minato, K; Nishikawa, M; Nogami, N; Okamoto, H; Seki, N; Seto, T; Shinkai, T; Takiguchi, Y; Watanabe, K | 1 |
| Berard, H; Bota, S; Chouaid, C; Corre, R; Crequit, J; Dujon, C; Paillotin, D; Robinet, G; Thomas, P; Vergnenegre, A | 1 |
| Jiang, J; Li, L; Lin, Q; Tian, J; Wang, Q; Wang, X | 1 |
| Fan, Y; Huang, ZY; Luo, LH; Yu, HF | 1 |
| Heijmen, BJ; Hoogeman, MS; Levendag, PC; Nuyttens, JJ; van de Water, S; van der Holt, B; van der Voort van Zyp, NC | 1 |
| Murphy, M; Stordal, B | 1 |
| Baas, P; Beijnen, JH; Burgers, JA; Burylo, A; deJong, D; Huitema, AD; Joerger, M; Schellens, JH | 1 |
| Aakre, JA; Aubry, MC; Croghan, GA; Cunningham, JM; Johnson, C; Li, Y; Molina, J; Pankratz, VS; Sun, Z; Wampfler, JA; Wang, L; Wu, D; Yang, P | 1 |
| Bennouna, J; de Castro, J; Dingemans, AM; Gridelli, C; Griesinger, F; Grossi, F; Langer, C; Rossi, A; Thatcher, N; Wong, EK | 1 |
| Bégueret, H; Jougon, J; Le Morvan, V; Mathiaux, J; Pulido, M; Robert, J | 1 |
| Saijo, N | 1 |
| Douillard, JY; Jiang, GL; Kim, ES; Li, LY; Liao, ML; Milenkova, T; Sun, Y; Wu, YL | 1 |
| Bagust, A; Blundell, M; Boland, A; Davis, H; Dickson, R; Dundar, Y; Hockenhull, J; Martin Saborido, C; Oyee, J; Ramani, VS | 1 |
| Georgoulias, V; Pallis, AG | 1 |
| Jiang, T; Liang, J; Lv, H; Yao, R; Yu, Z; Zhou, F | 1 |
| Li, L; Wang, X; Xu, C; Zhang, Y | 1 |
| Alberola, V; Alfaro, V; Camps, C; Cobo, M; Dómine, M; Gutiérrez-Calderón, V; Isla, D; Lardelli, P; Massuti, B; Nieto, A; Provencio, M; Rosell, R; Tarón, M; Viñolas, N | 1 |
| Argiris, A; Ballas, MS; Belani, CP; Davies, A; Edelman, M; Gandara, DR; Gitlitz, BJ; Groshen, S; Hoffman, P; Koczywas, M; Liu, SV; Ramalingam, S; Tsao-Wei, DD; Vokes, EE | 1 |
| Du, X; Li, M; Liu, L; Lu, C; Shi, J; Sun, T; Tang, X; Xiao, L; Yang, M; Yu, D; Yuan, Q; Zhang, X; Zhang, Z | 1 |
| Li, LF; Li, W; Liu, XM; Qian, ZZ; Qiu, LH; Wang, HQ; Zhang, HL | 1 |
| Chen, Y; Han, L; Li, H; Shao, H; Zhang, X | 1 |
| Jaśkiewicz, P; Kowalski, DM; Krawczyk, P; Krzakowski, M; Kucharczyk, T; Milanowski, J; Mlak, R; Winiarczyk, K; Wojas-Krawczyk, K | 1 |
| Cao, DD; Chen, Y; Ge, W; Jie, FF; Wang, HM; Zheng, YF | 1 |
| Chen, H; Fan, W; Gao, Z; Gu, S; Han, B; Jin, L; Lu, D; Qian, J; Tan, X; Wang, H; Wang, J; Wei, Q; Wu, Q; Wu, W; Zhang, W; Zhao, X | 1 |
| An, TT; Bai, H; Duan, JC; Liu, XH; Wang, J; Wang, SH; Wang, YY; Wang, ZJ; Wu, MN; Yang, L; Zhao, J; Zhuo, ML | 1 |
| Bian, B; Hu, N; Li, Y; Wu, F; Xu, G; Zheng, Y | 1 |
| Albert, I; Azzoli, CG; Bodkin, D; Iannotti, NO; Jiang, PY; Juhász, E; Kelly, K; Koutsoukos, T; Patel, JD; Pereira, JR; Weems, G; Zatloukal, P | 1 |
| Chang, GC; Chen, YM; Cheng, YK; Liao, WY; Shih, JY; Yang, JC; Yu, CJ | 1 |
| Bennis, R; Bruce, RH; Das, M; Frankel, P; Hsieh, HB; Liu, X; Ly, JC; Nieva, JJ; Riess, JW; Schwartz, E; Wakelee, HA; Zhou, L | 1 |
| Guo, S; Hu, J; Jin, L; Li, Q; Liu, J; Lu, D; Wang, JC; Wang, L; Wu, J; Ying, J; Zhao, N; Zhou, Y; Zou, H | 1 |
| Huang, Q; Liu, ZQ; Yin, JY; Zhao, YC; Zhou, HH | 1 |
| Chen, H; Chen, W; Fan, W; Gu, S; Han, B; Jin, L; Lu, D; Qian, J; Qu, HQ; Tan, X; Wang, H; Wang, J; Wang, Q; Wei, Q; Wu, J; Wu, Q; Wu, W; Yang, L; Yin, M; Zhao, X | 1 |
| He, J; Li, H; Lu, J; Ma, P; Qin, Y; Wang, J; Wei, L; Xu, J; Zhang, X | 1 |
| Chow, CW; Fujimoto, J; He, G; Kalhor, N; Kim, ES; Lee, JJ; Siddik, ZH; Stewart, DJ; Swisher, SG; Wistuba, II | 1 |
| Fandzloch, M; Muzioł, T; Sitkowski, J; Wietrzyk, J; Łakomska, I | 1 |
| Hu, J; Lu, FF; Shang, LH; Wei, HB; Wei, M; Yu, Y; Zhang, YY | 1 |
| Baldotto, C; Bennouna, J; Ciuleanu, TE; Goksel, T; Gorbunova, V; Le-Guennec, S; Miller, V; Novello, S; Ozguroglu, M; Ramlau, R; Rey, A; Scagliotti, G; Shepherd, FA; Thatcher, N | 1 |
| Hashemi-Sadraei, N; Pennell, NA | 1 |
| Cohen, J; Halm, EA; Mandeli, J; Mhango, G; Sigel, K; Strauss, G; Wisnivesky, J | 1 |
| Gao, G; Li, A; Li, X; Ren, S; Xu, J; Zhang, J; Zhang, L; Zhou, C | 1 |
| Hwang, YI; Jang, SH; Jung, KS; Kim, DG; Kim, JH; Kim, SY; Park, S | 1 |
| Guan, ZZ; Guo, Y; Huang, H; Jiang, WQ; Li, S; Liao, H; Yang, XQ; Zhan, J; Zou, BY | 1 |
| Duan, Z; He, C; Li, P; Xu, Q; Yuan, Y | 1 |
| Chu, Z; Huang, R; Jiang, J; Liang, X; Zhan, Q; Zhou, X | 1 |
| Burgers, SA; Dingemans, AM; Groen, HJ; Heideman, DA; Kunst, PW; Mellema, WW; Smit, EF; Thunnissen, E; van Wijk, A | 1 |
| Correa, AM; Erasmus, JJ; Gold, KA; Heymach, J; Kalhor, N; Kim, ES; Lee, JJ; Munden, R; Papadimitrakopoulou, V; Pataer, A; Rice, DC; Swisher, SG; William, WN; Wistuba, II | 1 |
| Ji, L; Pei, Y | 1 |
| Delauter, BJ; Egorin, MJ; Eiseman, JL; Gervais, AC; Grim, A; Hamburger, DR; Joseph, E; Pluim, D; Potter, DM; Schellens, JH; Zamboni, WC; Zuhowski, EG | 1 |
| Andre, F; Fandi, A; Fossella, F; Herbst, RS; Le Chevalier, T; Lee, JJ; Liu, DD; Massarelli, E; Ochs, J; Wolf, M | 1 |
| Blay, P; Buesa, JM; Esteban, E; Estrada, E; Fernández, Y; Fra, J; Lacave, AJ; Mareque, B; Muñiz, I; Palacio, I; Sánchez, R; Uña, E; Vieitez, JM; Villanueva, N | 1 |
| Kim, CH; Kim, HT; Lee, JC; Park, YH; Ryoo, BY | 1 |
| Christiani, DC; Gurubhagavatula, S; Liu, G; Lynch, TJ; Neuberg, DS; Park, S; Su, L; Wain, JC; Zhou, W | 1 |
| Bak, JY; Bang, YJ; Choi, IS; Heo, DS; Kim, DW; Kim, JH; Kim, NK; Kim, SI; Kim, TY; Kim, YT; Kim, YW; Kwon, JH; Oh, DY; Park, CI; Park, SR; Sung, SW; You, CK | 1 |
| Lin, DX; Miao, XP; Sun, Y; Tan, W; Wang, ZH; Xu, BH; Yuan, P; Zhang, XM | 1 |
| Baas, P; Beijnen, JH; Crul, M; Pluim, D; Rademaker-Lakhai, JM; Schellens, JH; Sparidans, RW; van Zandwijk, N | 1 |
| Brunetti, C; Cassano, G; Colucci, G; Galetta, D; Gebbia, V; Germano, D; Giampaglia, M; Guida, M; Izzi, G; Lorusso, V; Nettis, G; Silvestris, N; Spada, M | 1 |
| Ballas, MS; Dennis, PA | 1 |
| Kunitoh, H; Nokihara, H; Ohe, Y; Saijo, N; Sekine, I; Tamura, T; Yamamoto, N | 1 |
| Belani, CP; Fidias, P; Fossella, F; Gorbounova, V; Kaukel, E; Mattson, KV; Millward, M; Pereira, JR; Pluzanska, A; Ramlau, R; Szczesna, A; von Pawel, J | 1 |
| Hotta, K; Kiura, K | 1 |
| Ahn, JS; Ahn, YC; Choi, YS; Kim, H; Kim, J; Kim, K; Park, BB; Park, JO; Park, K; Shim, YM | 1 |
| Horai, T; Kasahara, K; Nishio, M; Ohyanagi, F; Shibata, K; Shirosaki, H; Taguchi, F; Takeda, Y | 1 |
| Anderson, H; Lorigan, P; Margison, GP; Margison, JM; Martin, F; Ranson, M; Thatcher, N; White, SC | 1 |
| Lester, JF; Macbeth, FR | 1 |
| Gadgeel, SM; Heath, EI; Heilbrun, LK; Ruckdeschel, JC; Venkatramanamoorthy, R; Wozniak, A | 1 |
| Mountzios, G; Olaussen, KA; Soria, JC | 1 |
| Edelman, MJ; Lustberg, MB | 1 |
| Jett, JR; Keith, RL; Kesler, KA; Schild, SE | 1 |
| Duarte, RL; Luiz, RR; Paschoal, ME | 1 |
| Belani, C; Ramalingam, S | 1 |
| Barlési, F; Breen, D | 1 |
| Lee, R; Leighl, NB; Loreto, M; Ng, R | 1 |
| Bernard, JP; Fournel, P; Jorda, M; Laennec, E; Piperno, D; Rebattu, P; Souquet, PJ; Trillet, V | 1 |
| Kimbara, K; Kunitoh, H; Nagatomo, A; Okamoto, H; Watanabe, K | 1 |
| Asoh, H; Fukuyama, Y; Ichinose, Y; Kuninaka, S; Miyagi, J; Terazaki, Y; Yano, T; Yokoyama, H | 1 |
| De Ruysscher, D; Demedts, M; Spaas, P; Specenier, P; Van den Brande, P; Vansteenkiste, J | 1 |
| Bergman, AM; Kuiper, CM; Peters, GJ; Pinedo, HM; van der Vijgh, WJ; van Moorsel, CJ; Veerman, G; Vermorken, JB | 1 |
| Coosemans, W; De Leyn, P; Deneffe, G; Lerut, T; Van Raemdonck, D; Vansteenkiste, J | 1 |
| Genvresse, I; Harder, H; Lange, C; Possinger, K; Schanz, J; Schweigert, M; Späth-Schwalbe, E | 1 |
| Kalofonos, HP; Kosmas, C; Koutras, A; Malamos, N; Onyenadum, A; Polyzos, A; Rokana, S; Stavroyianni, N; Tsavaris, N; Vadiaka, M | 1 |
| Bernareggi, A; Castoldi, D; Cimino, G; Colombi, L; Fracasso, ME; Leone, R; Monzani, V; Soresi, E; Tedeschi, M; Usari, T | 1 |
| Elliott, WL; Farrell, NP; Hoeschele, JD; Kraker, AJ; Sercel, AD; Showalter, HD | 1 |
| Eguchi, K; Ohe, Y; Ohmori, T; Saijo, N; Sasaki, Y; Shinkai, T; Tamura, T | 1 |
| Bres, J; Cupissol, D; Gestin-Boyer, C; Michel, FB; Pujol, JL; Serrou, B | 1 |
| Hayashibara, K; Hirosawa, A; Niitani, H; Tsuboi, E | 1 |
| Murakami, M | 1 |
| DeGregorio, MW; Deisseroth, AB; Gandara, DR; George, CB; Kohler, M; Lawrence, HJ; Wilbur, BJ; Wold, H | 1 |
| Abad-Esteve, A; Fernandez, C; Monras, P; Moreno, I; Morera, J; Ribas-Mundo, M; Rosell, R; Ruiz, J | 1 |
50 review(s) available for platinum and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Traditional herbal medicine combined with first-line platinum-based chemotherapy for advanced non-small-cell lung cancer: A PRISMA-compliant systematic review and meta-analysis.
Topics: Carcinoma, Non-Small-Cell Lung; Drug Therapy; Humans; Medicine, Traditional; Platinum; Progression-Free Survival; Survival Analysis | 2021 |
Best regimens for treating chemo-naïve incurable squamous non-small cell lung cancer with a programmed death-ligand 1 tumor proportion score of 1%-49%: A network meta-analysis.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Humans; Immune Checkpoint Inhibitors; Ipilimumab; Lung Neoplasms; Nivolumab; Platinum; Progression-Free Survival; Randomized Controlled Trials as Topic | 2022 |
Overall Survival and Safety With Pemetrexed/Platinum ± Anti-VEGF Followed by Pemetrexed ± Anti-VEGF Maintenance in Advanced Nonsquamous Non-Small-Cell Lung Cancer: A Pooled Analysis of 4 Randomized Studies.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Pemetrexed; Platinum | 2022 |
BRCA1 expression associated with the prognostic value of platinum-based chemotherapy for stage II-IV non-small cell lung cancer: A meta-analysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; BRCA1 Protein; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Platinum; Prognosis | 2022 |
Investigation of the optimal platinum-based regimen in the postoperative adjuvant chemotherapy setting for early-stage resected non-small lung cancer: a Bayesian network meta-analysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Cisplatin; Humans; Lung Neoplasms; Neoplasm Recurrence, Local; Network Meta-Analysis; Platinum; Vinorelbine | 2022 |
Treatment Considerations for Patients With Advanced Squamous Cell Carcinoma of the Lung.
Topics: Afatinib; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Docetaxel; Humans; Lung; Lung Neoplasms; Platinum | 2022 |
A network meta-analysis of immunotherapy-based treatments for advanced nonsquamous non-small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Carcinoma, Non-Small-Cell Lung; Docetaxel; Humans; Immunotherapy; Lung Neoplasms; Network Meta-Analysis; Pemetrexed; Platinum | 2023 |
Continuation of osimertinib in EGFR-mutant non-small-cell lung cancer patients bearing CNS metastasis (EPONA study).
Topics: Aniline Compounds; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; ErbB Receptors; Humans; Lung Neoplasms; Mutation; Pemetrexed; Platinum; Protein Kinase Inhibitors | 2023 |
Surgical and survival outcomes with perioperative or neoadjuvant immune-checkpoint inhibitors combined with platinum-based chemotherapy in resectable NSCLC: A systematic review and meta-analysis of randomised clinical trials.
Topics: B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Humans; Immune Checkpoint Inhibitors; Lung Neoplasms; Neoadjuvant Therapy; Platinum; Randomized Controlled Trials as Topic | 2023 |
Efficacy and safety of Kanglaite injection combined with first-line platinum-based chemotherapy in patients with advanced NSCLC: a systematic review and meta-analysis of 32 RCTs.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Drugs, Chinese Herbal; Humans; Lung Neoplasms; Platinum | 2020 |
Necitumumab plus platinum-based chemotherapy versus chemotherapy alone as first-line treatment for stage IV non-small cell lung cancer: a meta-analysis based on randomized controlled trials.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Platinum; Randomized Controlled Trials as Topic | 2021 |
Platinum-based chemotherapy in combination with PD-1/PD-L1 inhibitors: preclinical and clinical studies and mechanism of action.
Topics: Adult; Animals; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Humans; Immune Checkpoint Inhibitors; Liver Neoplasms; Lung Neoplasms; Mice; Nasopharyngeal Neoplasms; Phosphatidylinositol 3-Kinases; Platinum; Programmed Cell Death 1 Receptor; Tumor Microenvironment | 2021 |
The impacts of race and regimens on the efficacy and safety of paclitaxel and platinum combination treatment for patients with advanced non-small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asian People; Carcinoma, Non-Small-Cell Lung; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Lung Neoplasms; Monte Carlo Method; Neoplasm Staging; Paclitaxel; Platinum; Survival Analysis | 2021 |
Evaluation of Prediction of Polymorphisms of DNA Repair Genes on the Efficacy of Platinum-Based Chemotherapy in Patients With Non-Small Cell Lung Cancer: A Network Meta-Analysis.
Topics: Carcinoma, Non-Small-Cell Lung; DNA Repair; Humans; Lung Neoplasms; Neoplasm Proteins; Platinum; Polymorphism, Genetic | 2017 |
Genetic Polymorphisms and Platinum-based Chemotherapy Treatment Outcomes in Patients with Non-Small Cell Lung Cancer: A Genetic Epidemiology Study Based Meta-analysis.
Topics: Antineoplastic Agents; Asian People; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; China; Humans; Lung Neoplasms; Molecular Epidemiology; Pharmacogenetics; Platinum; Polymorphism, Single Nucleotide; Treatment Outcome | 2017 |
The best platinum regimens for chemo-naive incurable non-small cell lung cancer: network meta-analysis.
Topics: Antineoplastic Agents; Bevacizumab; Carcinoma, Non-Small-Cell Lung; Cisplatin; Deoxycytidine; Docetaxel; Gemcitabine; Humans; Lung Neoplasms; Network Meta-Analysis; Paclitaxel; Platinum | 2017 |
Anticancer drug treatment for advanced lung cancer with interstitial lung disease.
Topics: Albumins; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Disease Progression; Etoposide; Follow-Up Studies; Humans; Lung Diseases, Interstitial; Lung Neoplasms; Paclitaxel; Platinum; Retrospective Studies; Risk Assessment; Risk Factors | 2018 |
Interstitial lung disease associated with gefitinib in Japanese patients with EGFR-mutated non-small-cell lung cancer: combined analysis of two Phase III trials (NEJ 002 and WJTOG 3405).
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase III as Topic; ErbB Receptors; Female; Gefitinib; Humans; Lung Diseases, Interstitial; Lung Neoplasms; Male; Middle Aged; Mutation; Platinum; Protein Kinase Inhibitors; Quinazolines; Smoking | 2013 |
Association of ERCC1-C118T and -C8092A polymorphisms with lung cancer risk and survival of advanced-stage non-small cell lung cancer patients receiving platinum-based chemotherapy: a pooled analysis based on 39 reports.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Case-Control Studies; DNA-Binding Proteins; Endonucleases; Humans; Lung Neoplasms; Neoplasm Staging; Odds Ratio; Platinum; Polymorphism, Single Nucleotide; Publication Bias; Risk; Treatment Outcome | 2013 |
Platinum rechallenge in patients with advanced NSCLC: a pooled analysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Neoplasm Staging; Odds Ratio; Platinum; Publication Bias; Retreatment; Treatment Outcome | 2013 |
XRCC3 Thr241Met polymorphism and clinical outcomes of NSCLC patients receiving platinum-based chemotherapy: a systematic review and meta-analysis.
Topics: Alleles; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Humans; Lung Neoplasms; Platinum; Polymorphism, Genetic; Treatment Outcome | 2013 |
XRCC3 Thr241Met is associated with response to platinum-based chemotherapy but not survival in advanced non-small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Female; Humans; Lung; Lung Neoplasms; Male; Middle Aged; Platinum; Polymorphism, Single Nucleotide; Prognosis; Treatment Outcome | 2013 |
Influence of methylenetetrahydrofolate reductase C677T polymorphism on the risk of lung cancer and the clinical response to platinum-based chemotherapy for advanced non-small cell lung cancer: an updated meta-analysis.
Topics: Carcinoma, Non-Small-Cell Lung; Genetic Predisposition to Disease; Humans; Lung Neoplasms; Methylenetetrahydrofolate Reductase (NADPH2); Platinum; Polymorphism, Genetic | 2013 |
The association between the ERCC1/2 polymorphisms and the clinical outcomes of the platinum-based chemotherapy in non-small cell lung cancer (NSCLC): a systematic review and meta-analysis.
Topics: Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; DNA-Binding Proteins; Endonucleases; Humans; Lung Neoplasms; Platinum; Polymorphism, Single Nucleotide; Treatment Outcome; Xeroderma Pigmentosum Group D Protein | 2014 |
The association between the GSTP1 A313G and GSTM1 null/present polymorphisms and the treatment response of the platinum-based chemotherapy in non-small cell lung cancer (NSCLC) patients: a meta-analysis.
Topics: Asian People; Biomarkers, Pharmacological; Carcinoma, Non-Small-Cell Lung; Genetic Predisposition to Disease; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Platinum; Polymorphism, Single Nucleotide | 2014 |
[A meta-analysis of platinum plus docetaxel or vinorelbine in the first-line treatment of advanced non-small cell lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Docetaxel; Humans; Lung Neoplasms; Platinum; Randomized Controlled Trials as Topic; Taxoids; Vinblastine; Vinorelbine | 2014 |
Polymorphisms in the XRCC1 gene are associated with treatment response to platinum chemotherapy in advanced non-small cell lung cancer patients based on meta-analysis.
Topics: Alleles; Carcinoma, Non-Small-Cell Lung; China; DNA-Binding Proteins; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Neoplasm Staging; Platinum; Polymorphism, Single Nucleotide; Treatment Outcome; X-ray Repair Cross Complementing Protein 1 | 2014 |
What can platinum offer yet in the treatment of PS2 NSCLC patients? A systematic review and meta-analysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Platinum; Randomized Controlled Trials as Topic; Survival Rate | 2015 |
Pemetrexed With Platinum Combination as a Backbone for Targeted Therapy in Non-Small-Cell Lung Cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Humans; Lung Neoplasms; Molecular Targeted Therapy; Pemetrexed; Platinum | 2016 |
Pharmacogenomics of platinum-based chemotherapy response in NSCLC: a genotyping study and a pooled analysis.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; DNA Repair; DNA-Binding Proteins; Female; Genotype; Humans; Lung Neoplasms; Male; Middle Aged; Pharmacogenetics; Platinum; Polymorphism, Single Nucleotide; X-ray Repair Cross Complementing Protein 1 | 2016 |
Chemotherapy for Advanced Non-Small-Cell Lung Cancer in Elderly Patients.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Humans; Neoplasm Staging; Platinum; Randomized Controlled Trials as Topic | 2016 |
Can Aidi injection restore cellular immunity and improve clinical efficacy in non-small-cell lung cancer patients treated with platinum-based chemotherapy? A meta-analysis of 17 randomized controlled trials following the PRISMA guidelines.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drugs, Chinese Herbal; Humans; Immunity, Cellular; Injections; Lung Neoplasms; Phytotherapy; Platinum; Randomized Controlled Trials as Topic; Treatment Outcome | 2016 |
Meta-analysis examining impact of age on overall survival with pemetrexed for the treatment of advanced non-squamous non-small cell lung cancer.
Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Clinical Trials, Phase III as Topic; Disease-Free Survival; Humans; Lung Neoplasms; Pemetrexed; Platinum; Retrospective Studies; Treatment Outcome | 2017 |
Research Advances in Resistance to Platinum-based Chemotherapy in Lung Cancer.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; Platinum; Prognosis | 2017 |
A meta-analysis of platinum plus gemcitabine or vinorelbine in the treatment of advanced non-small-cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Databases, Bibliographic; Deoxycytidine; Disease Progression; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Middle Aged; Odds Ratio; Platinum; Vinblastine; Vinorelbine | 2009 |
[A meta analysis of gemcitabine plus platinum chemotherapy compared with single-agent chemotherapy in the treatment of non-small cell lung cancer].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Gemcitabine; Humans; Lung Neoplasms; Platinum; Treatment Outcome | 2010 |
[A meta-analysis of pemetrexed plus platinum chemotherapy versus gemcitabine plus platinum chemotherapy for advanced non-small cell lung cancer].
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Drug Therapy, Combination; Gemcitabine; Glutamates; Guanine; Humans; Lung Neoplasms; Pemetrexed; Platinum; Randomized Controlled Trials as Topic; Survival Rate; Treatment Outcome | 2011 |
Erlotinib or gefitinib for the treatment of relapsed platinum pretreated non-small cell lung cancer and ovarian cancer: a systematic review.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Drug Resistance, Multiple; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Female; Gefitinib; Gene Dosage; Gene Expression; Humans; Lung Neoplasms; Mutation; Ovarian Neoplasms; Platinum; Protein Kinase Inhibitors; Quinazolines; Recurrence; Survival Rate; Treatment Outcome | 2011 |
Problems involved in the clinical trials for non-small cell lung carcinoma.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Glutamates; Guanine; Humans; Lung Neoplasms; Maintenance Chemotherapy; Mutation; Patient Selection; Pemetrexed; Platinum; Quinazolines | 2012 |
Is there a standard regimen for first-line treatment of advanced/metastatic Non-Small-Cell Lung Cancer? What has meta-analyses contributed to today's standard of care.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cisplatin; Humans; Lung Neoplasms; Meta-Analysis as Topic; Platinum; Standard of Care | 2012 |
Pharmacogenetic role of ERCC1 genetic variants in treatment response of platinum-based chemotherapy among advanced non-small cell lung cancer patients.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Endonucleases; Genetic Heterogeneity; Genetic Variation; Humans; Lung Neoplasms; Neoplasm Staging; Platinum; Polymorphism, Single Nucleotide; Prognosis; Publication Bias; Treatment Outcome | 2012 |
Endostar combined with chemotherapy versus chemotherapy alone for advanced NSCLCs: a meta-analysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Endostatins; Humans; Leukopenia; Lung Neoplasms; Nausea; Platinum; Randomized Controlled Trials as Topic; Recombinant Proteins; Thrombocytopenia; Treatment Outcome; Vomiting | 2011 |
Predictive value of XRCC1 gene polymorphisms on platinum-based chemotherapy in advanced non-small cell lung cancer patients: a systematic review and meta-analysis.
Topics: Alleles; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Lung Neoplasms; Neoplasm Staging; Platinum; Polymorphism, Genetic; Prognosis; Treatment Outcome; X-ray Repair Cross Complementing Protein 1 | 2012 |
Meta-analysis on pharmacogenetics of platinum-based chemotherapy in non small cell lung cancer (NSCLC) patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Pharmacogenetics; Platinum; Polymorphism, Single Nucleotide; Prognosis | 2012 |
Pemetrexed plus platinum or gemcitabine plus platinum for advanced non-small cell lung cancer: final survival analysis from a multicentre randomized phase II trial in the East Asia region and a meta-analysis.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asia; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Female; Gemcitabine; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Middle Aged; Pemetrexed; Platinum; Survival Analysis; Treatment Outcome | 2013 |
A meta-analytic review of ERCC1/MDR1 polymorphism and chemosensitivity to platinum in patients with advanced non-small cell lung cancer.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Endonucleases; Humans; Lung Neoplasms; Platinum; Polymorphism, Genetic | 2012 |
ERCC1 as a risk stratifier in platinum-based chemotherapy for nonsmall-cell lung cancer.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cisplatin; DNA-Binding Proteins; Endonucleases; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Platinum; Prognosis; Risk Factors; RNA, Neoplasm | 2007 |
Optimal duration of chemotherapy in advanced non-small cell lung cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Drug Administration Schedule; ErbB Receptors; Humans; Lung Neoplasms; Medical Oncology; Neoplasm Staging; Platinum; Quality of Life; Time Factors; Treatment Outcome | 2007 |
Systemic chemotherapy for advanced non-small cell lung cancer: recent advances and future directions.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Erlotinib Hydrochloride; Gemcitabine; Glutamates; Guanine; Humans; Lung Neoplasms; Neoplasm Staging; Pemetrexed; Platinum; Protein Kinase Inhibitors; Quality of Life; Quinazolines; Survival Rate; Taxoids; Treatment Outcome | 2008 |
The place of excision repair cross complementation 1 (ERCC1) in surgically treated non-small cell lung cancer.
Topics: Antineoplastic Agents; Biomarkers; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; DNA Repair; DNA-Binding Proteins; Endonucleases; Humans; Lung Neoplasms; Platinum; Predictive Value of Tests; Survival Rate | 2008 |
95 trial(s) available for platinum and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Study Design and Rationale for Espera Trial: A Multicentre, Randomized, Phase II Clinical Trial Evaluating the Potential Efficacy of Adding SBRT to Pembrolizumab-Pemetrexed Maintenance in Responsive or Stable Advanced Non-Squamous NSCLC After Chemo-Immuno
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Humans; Immunotherapy; Lung Neoplasms; Pemetrexed; Platinum; Radiosurgery; Tumor Microenvironment | 2022 |
Treatment Outcomes and Safety of Mobocertinib in Platinum-Pretreated Patients With EGFR Exon 20 Insertion-Positive Metastatic Non-Small Cell Lung Cancer: A Phase 1/2 Open-label Nonrandomized Clinical Trial.
Topics: Aniline Compounds; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Exons; Female; Humans; Indoles; Lung Neoplasms; Platinum; Protein Kinase Inhibitors; Pyrimidines; Treatment Outcome | 2021 |
Adding Base-Excision Repair Inhibitor TRC102 to Standard Pemetrexed-Platinum-Radiation in Patients with Advanced Nonsquamous Non-Small Cell Lung Cancer: Results of a Phase I Trial.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; DNA Repair; Glutamates; Guanine; Humans; Lung Neoplasms; Pemetrexed; Platinum | 2022 |
CCTG BR34: A Randomized Phase 2 Trial of Durvalumab and Tremelimumab With or Without Platinum-Based Chemotherapy in Patients With Metastatic NSCLC.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Platinum | 2022 |
A Multicenter, Randomized Phase III Study Comparing Platinum Combination Chemotherapy Plus Pembrolizumab With Platinum Combination Chemotherapy Plus Nivolumab and Ipilimumab for Treatment-Naive Advanced Non-Small Cell Lung Cancer Without Driver Gene Alter
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Humans; Ipilimumab; Lung Neoplasms; Nivolumab; Platinum; Programmed Cell Death 1 Receptor | 2022 |
Pharmacological ascorbate improves the response to platinum-based chemotherapy in advanced stage non-small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Humans; Leukocytes, Mononuclear; Lung Neoplasms; Paclitaxel; Platinum | 2022 |
A Phase 2 Study of Docetaxel, Ramucirumab, and Pembrolizumab for Patients With Metastatic or Recurrent Non-Small-Cell Lung Cancer (NSCLC) who Progressed on Platinum-Doublet and PD-1/PD-L1 Blockade.
Topics: Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Docetaxel; Humans; Immune Checkpoint Inhibitors; Lung Neoplasms; Neoplasm Recurrence, Local; Platinum; Programmed Cell Death 1 Receptor; Ramucirumab | 2022 |
Final overall survival data of sintilimab plus pemetrexed and platinum as First-Line treatment for locally advanced or metastatic nonsquamous NSCLC in the Phase 3 ORIENT-11 study.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Humans; Lung Neoplasms; Pemetrexed; Platinum; Receptor Protein-Tyrosine Kinases | 2022 |
A Randomized Comparison of Nivolumab versus Nivolumab + Docetaxel for Previously Treated Advanced or Recurrent ICI-Naïve Non-Small Cell Lung Cancer: TORG1630.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Docetaxel; Humans; Immune Checkpoint Inhibitors; Lung Neoplasms; Neoplasm Recurrence, Local; Nivolumab; Platinum | 2022 |
Cemiplimab plus chemotherapy versus chemotherapy alone in non-small cell lung cancer: a randomized, controlled, double-blind phase 3 trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Double-Blind Method; Humans; Lung Neoplasms; Platinum; Protein-Tyrosine Kinases; Proto-Oncogene Proteins | 2022 |
Results from the IMpower132 China cohort: Atezolizumab plus platinum-based chemotherapy in advanced non-small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cisplatin; Disease-Free Survival; Humans; Lung Neoplasms; Pemetrexed; Platinum | 2023 |
A phase II, multicenter study of lazertinib as consolidation therapy in patients with locally advanced, unresectable, EGFR mutation-positive non-small cell lung cancer (stage III) who have not progressed following definitive, platinum-based, chemoradiatio
Topics: Carcinoma, Non-Small-Cell Lung; Chemoradiotherapy; Consolidation Chemotherapy; ErbB Receptors; Humans; Lung Neoplasms; Mutation; Platinum; Prospective Studies; Protein Kinase Inhibitors | 2022 |
Patient-reported outcomes with cemiplimab monotherapy for first-line treatment of advanced non-small cell lung cancer with PD-L1 of ≥50%: The EMPOWER-Lung 1 study.
Topics: Adult; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Humans; Lung; Lung Neoplasms; Pain; Patient Reported Outcome Measures; Platinum; Quality of Life | 2023 |
Neoadjuvant toripalimab plus platinum-paclitaxel chemotherapy in stage II-III non-small cell lung cancer: a single-center, single-arm, phase I study in China.
Topics: Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Neoadjuvant Therapy; Paclitaxel; Platinum | 2023 |
Sintilimab plus autologous NK cells as second-line treatment for advanced non-small-cell lung cancer previous treated with platinum-containing chemotherapy.
Topics: Carcinoma, Non-Small-Cell Lung; Humans; Killer Cells, Natural; Lung Neoplasms; Pilot Projects; Platinum | 2022 |
A phase II study (WJOG12819L) to assess the efficacy of osimertinib in patients with EGFR mutation-positive NSCLC in whom systemic disease (T790M-negative) progressed after treatment with first- or second-generation EGFR TKIs and platinum-based chemothera
Topics: Aniline Compounds; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Genes, erbB-1; Humans; Lung Neoplasms; Mutation; Platinum; Protein Kinase Inhibitors | 2023 |
Atezolizumab with or without bevacizumab and platinum-pemetrexed in patients with stage IIIB/IV non-squamous non-small cell lung cancer with EGFR mutation, ALK rearrangement or ROS1 fusion progressing after targeted therapies: A multicentre phase II open-
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Female; Humans; Lung Neoplasms; Middle Aged; Mutation; Pemetrexed; Platinum; Protein-Tyrosine Kinases; Proto-Oncogene Proteins | 2023 |
Patients' voice and passion lead to successful clinical trial, KISEKI study; Comments on "A phase II study (WJOG12819L) to assess the efficacy of osimertinib in patients with EGFR mutation-positive NSCLC in whom systemic disease (T790M-negative) progresse
Topics: Aniline Compounds; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Humans; Lung Neoplasms; Mutation; Platinum; Protein Kinase Inhibitors | 2023 |
FDA Approval Summary: Atezolizumab as Adjuvant Treatment following Surgical Resection and Platinum-Based Chemotherapy for Stage II to IIIA NSCLC.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Platinum | 2023 |
Quality of life with cemiplimab plus chemotherapy for first-line treatment of advanced non-small cell lung cancer: Patient-reported outcomes from phase 3 EMPOWER-Lung 3.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Female; Humans; Lung; Lung Neoplasms; Male; Middle Aged; Pain; Patient Reported Outcome Measures; Platinum; Quality of Life | 2023 |
Rationale and Design of the Phase II ANTELOPE Study of Atezolizumab, Carboplatin and nab-Paclitaxel vs. Pembrolizumab, Platinum and Pemetrexed in TTF-1 Negative, Metastatic Lung Adenocarcinoma (AIO-TRK-0122).
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Pemetrexed; Platinum; Retrospective Studies; Thyroid Nuclear Factor 1 | 2023 |
Efficacy and safety of KN046, a novel bispecific antibody against PD-L1 and CTLA-4, in patients with non-small cell lung cancer who failed platinum-based chemotherapy: a phase II study.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; CTLA-4 Antigen; Humans; Lung Neoplasms; Platinum | 2023 |
First-line atezolizumab monotherapy versus single-agent chemotherapy in patients with non-small-cell lung cancer ineligible for treatment with a platinum-containing regimen (IPSOS): a phase 3, global, multicentre, open-label, randomised controlled study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Platinum; Quality of Life | 2023 |
First-line nivolumab, paclitaxel, carboplatin, and bevacizumab for advanced non-squamous non-small cell lung cancer: Updated survival analysis of the ONO-4538-52/TASUKI-52 randomized controlled trial.
Topics: Bevacizumab; Carboplatin; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Humans; Lung Neoplasms; Neoplasm Recurrence, Local; Nivolumab; Paclitaxel; Platinum; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Survival Analysis | 2023 |
HERTHENA-Lung01, a Phase II Trial of Patritumab Deruxtecan (HER3-DXd) in Epidermal Growth Factor Receptor-Mutated Non-Small-Cell Lung Cancer After Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy and Platinum-Based Chemotherapy.
Topics: Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Humans; Lung Neoplasms; Mutation; Platinum; Protein Kinase Inhibitors | 2023 |
Nivolumab as maintenance therapy following platinum-based chemotherapy in EGFR-mutant lung cancer patients after tyrosine kinase inhibitor failure: A single-arm, open-label, phase 2 trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Humans; Lung Neoplasms; Mutation; Nivolumab; Platinum; Prospective Studies; Protein Kinase Inhibitors; Tyrosine Kinase Inhibitors | 2023 |
Neoadjuvant nivolumab with or without platinum-doublet chemotherapy based on PD-L1 expression in resectable NSCLC (CTONG1804): a multicenter open-label phase II study.
Topics: B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Neoadjuvant Therapy; Nivolumab; Platinum; Prospective Studies | 2023 |
The clinical role of VeriStrat testing in patients with advanced non-small cell lung cancer considered unfit for first-line platinum-based chemotherapy.
Topics: Adenocarcinoma of Lung; Aged; Aged, 80 and over; Biomarkers, Tumor; Blood Proteins; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Double-Blind Method; Erlotinib Hydrochloride; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Predictive Value of Tests; Protein Kinase Inhibitors; Proteomics; Survival Rate | 2019 |
Nab-paclitaxel in older patients with non-small cell lung cancer who have developed disease progression after platinum-based doublet chemotherapy.
Topics: Adenocarcinoma of Lung; Aged; Aged, 80 and over; Albumins; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Paclitaxel; Platinum; Prognosis; Retrospective Studies; Salvage Therapy; Survival Rate | 2020 |
Exploratory analysis of front-line therapies in REVEL: a randomised phase 3 study of ramucirumab plus docetaxel versus docetaxel for the treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Disease Progression; Docetaxel; Female; Humans; Lung Neoplasms; Neoplasm Staging; Platinum; Ramucirumab | 2020 |
Nivolumab safety and efficacy in advanced, platinum-resistant, non-small cell lung cancer, radical radiotherapy-ineligible patients: A phase II study in Taiwan.
Topics: Carcinoma, Non-Small-Cell Lung; Chemoradiotherapy; Drug Resistance, Neoplasm; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Nivolumab; Platinum; Taiwan | 2020 |
Updated Analysis From KEYNOTE-189: Pembrolizumab or Placebo Plus Pemetrexed and Platinum for Previously Untreated Metastatic Nonsquamous Non-Small-Cell Lung Cancer.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pemetrexed; Platinum | 2020 |
A Phase 2 Study of Tislelizumab in Combination With Platinum-Based Chemotherapy as First-line Treatment for Advanced Lung Cancer in Chinese Patients.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; China; Humans; Lung Neoplasms; Pemetrexed; Platinum | 2020 |
Osimertinib versus platinum-pemetrexed for patients with EGFR T790M advanced NSCLC and progression on a prior EGFR-tyrosine kinase inhibitor: AURA3 overall survival analysis.
Topics: Acrylamides; Adult; Aniline Compounds; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Humans; Lung Neoplasms; Mutation; Pemetrexed; Platinum; Protein Kinase Inhibitors; Survival Analysis | 2020 |
Targeted Natural Killer Cell-Based Adoptive Immunotherapy for the Treatment of Patients with NSCLC after Radiochemotherapy: A Randomized Phase II Clinical Trial.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Chemoradiotherapy; Combined Modality Therapy; Female; HSP70 Heat-Shock Proteins; Humans; Immunotherapy, Adoptive; Killer Cells, Natural; Male; Middle Aged; Neoplasm Staging; Platinum; Progression-Free Survival | 2020 |
A Phase II Study of Osimertinib Combined With Platinum Plus Pemetrexed in Patients With EGFR-Mutated Advanced Non-Small-cell Lung Cancer: The OPAL Study (NEJ032C/LOGIK1801).
Topics: Acrylamides; Aniline Compounds; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Humans; Lung Neoplasms; Mutation; Pemetrexed; Platinum; Progression-Free Survival; Safety; Treatment Outcome | 2021 |
C-reactive protein reduction post treatment is associated with improved survival in atezolizumab (anti-PD-L1) treated non-small cell lung cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; C-Reactive Protein; Carcinoma, Non-Small-Cell Lung; Female; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; ROC Curve | 2021 |
Metronomic oral vinorelbine in previously untreated advanced non-small-cell lung cancer patients unfit for platinum-based chemotherapy: results of the randomized phase II Tempo Lung trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Humans; Lung; Lung Neoplasms; Platinum; Prospective Studies; Quality of Life; Vinorelbine | 2021 |
Safety of pemetrexed plus platinum in combination with pembrolizumab for metastatic nonsquamous non-small cell lung cancer: A post hoc analysis of KEYNOTE-189.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Pemetrexed; Platinum | 2021 |
[Detection of Serum Peptides in Patients with Lung Squamous Cell Carcinoma by MALDI-TOF-MS and Analysis of Their Correlation with Chemotherapy Efficacy].
Topics: Adult; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Drug Monitoring; Female; Humans; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Peptides; Platinum; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Treatment Outcome; Young Adult | 2017 |
FDA Benefit-Risk Assessment of Osimertinib for the Treatment of Metastatic Non-Small Cell Lung Cancer Harboring Epidermal Growth Factor Receptor T790M Mutation.
Topics: Acrylamides; Adult; Aged; Aged, 80 and over; Aniline Compounds; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; ErbB Receptors; Female; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Neoplasm Metastasis; Platinum; Protein Kinase Inhibitors; Remission Induction; Risk Assessment; United States; United States Food and Drug Administration; Young Adult | 2018 |
Adjusted Indirect Comparison Using Propensity Score Matching of Osimertinib to Platinum-Based Doublet Chemotherapy in Patients with EGFRm T790M NSCLC Who Have Progressed after EGFR-TKI.
Topics: Acrylamides; Adult; Aged; Aged, 80 and over; Aniline Compounds; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; ErbB Receptors; Female; Humans; Lung Neoplasms; Male; Meta-Analysis as Topic; Middle Aged; Mutation; Piperazines; Platinum; Propensity Score; Protein Kinase Inhibitors | 2018 |
Osimertinib in Japanese patients with EGFR T790M mutation-positive advanced non-small-cell lung cancer: AURA3 trial.
Topics: Acrylamides; Adult; Aged; Aged, 80 and over; Anemia; Aniline Compounds; Antineoplastic Combined Chemotherapy Protocols; Asian People; Carcinoma, Non-Small-Cell Lung; Diarrhea; Disease-Free Survival; ErbB Receptors; Female; Humans; Japan; Lung Neoplasms; Male; Middle Aged; Mutation; Pemetrexed; Piperazines; Platinum; Protein Kinase Inhibitors; Young Adult | 2018 |
Phase 1B Study of Momelotinib Combined With Trametinib in Metastatic, Kirsten Rat Sarcoma Viral Oncogene Homolog-Mutated Non-Small-Cell Lung Cancer After Platinum-Based Chemotherapy Treatment Failure.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Carcinoma, Non-Small-Cell Lung; Female; Humans; Janus Kinases; Lung Neoplasms; Male; MAP Kinase Kinase 1; Middle Aged; Mutation; Neoplasm Metastasis; Platinum; Proto-Oncogene Proteins p21(ras); Pyridones; Pyrimidines; Pyrimidinones; Treatment Failure | 2018 |
EGFR mutation analysis for prospective patient selection in AURA3 phase III trial of osimertinib versus platinum-pemetrexed in patients with EGFR T790M-positive advanced non-small-cell lung cancer.
Topics: Acrylamides; Aniline Compounds; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Female; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Patient Selection; Pemetrexed; Platinum; Progression-Free Survival; Prospective Studies; Retrospective Studies | 2018 |
Second-line erlotinib after failure of pemetrexed-containing chemotherapy in advanced non-small cell lung cancer (NSCLC): Real-world effectiveness, safety and tolerability.
Topics: Adenocarcinoma of Lung; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Erlotinib Hydrochloride; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Pemetrexed; Platinum; Prognosis; Prospective Studies; Salvage Therapy; Survival Rate | 2019 |
AVAiLABLE NIS - AVASTIN® in lung cancer treatment in routine oncology practice in Germany.
Topics: Aged; Antineoplastic Agents, Immunological; Bevacizumab; Carcinoma, Non-Small-Cell Lung; Female; Germany; Humans; Lung Neoplasms; Maintenance Chemotherapy; Male; Middle Aged; Neoplasm Staging; Platinum; Standard of Care; Survival Analysis; Treatment Outcome | 2019 |
A pooled analysis of two phase II trials evaluating metformin plus platinum-based chemotherapy in advanced non-small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Female; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Metformin; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Platinum; Prognosis; Treatment Outcome | 2019 |
The association between COX-2 polymorphisms and hematologic toxicity in patients with advanced non-small-cell lung cancer treated with platinum-based chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cyclooxygenase 2; Female; Gene Frequency; Genetic Association Studies; Haplotypes; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Grading; Neoplasm Staging; Platinum; Polymorphism, Single Nucleotide; Treatment Outcome | 2013 |
Phase II study on Javanica oil emulsion injection (Yadanzi®) combined with chemotherapy in treating patients with advanced lung adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brucea; Carcinoma, Non-Small-Cell Lung; Case-Control Studies; Emulsions; Female; Follow-Up Studies; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Pemetrexed; Phytotherapy; Plant Oils; Platinum; Prognosis | 2013 |
Effect of Platinum-Based Chemoradiotherapy on Cellular Proliferation in Bone Marrow and Spleen, Estimated by (18)F-FLT PET/CT in Patients with Locally Advanced Non-Small Cell Lung Cancer.
Topics: Adult; Aged; Aged, 80 and over; Bone Marrow Cells; Carcinoma, Non-Small-Cell Lung; Cell Count; Cell Proliferation; Chemoradiotherapy; Dideoxynucleosides; Female; Fluorodeoxyglucose F18; Glucose; Humans; Lung Neoplasms; Male; Middle Aged; Neutrophils; Organ Specificity; Platinum; Positron-Emission Tomography; Spleen; Tomography, X-Ray Computed | 2014 |
DISRUPT: a randomised phase 2 trial of ombrabulin (AVE8062) plus a taxane-platinum regimen as first-line therapy for metastatic non-small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Carcinoma, Non-Small-Cell Lung; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Platinum; Serine; Taxoids; Treatment Outcome | 2014 |
Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): a multicentre, double-blind, randomised phase 3 trial.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Disease Progression; Docetaxel; Double-Blind Method; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Placebos; Platinum; Quality of Life; Ramucirumab; Survival Rate; Taxoids | 2014 |
Association of POLK polymorphisms with platinum-based chemotherapy response and severe toxicity in non-small cell lung cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; DNA-Directed DNA Polymerase; Female; Genotyping Techniques; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Polymorphism, Single Nucleotide; Treatment Outcome | 2014 |
A randomized phase II study of bevacizumab in combination with docetaxel or S-1 in patients with non-squamous non-small-cell lung cancer previously treated with platinum based chemotherapy (HANSHIN Oncology Group 0110).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Non-Small-Cell Lung; Docetaxel; Drug Combinations; Female; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Oxonic Acid; Platinum; Retreatment; Taxoids; Tegafur; Treatment Outcome | 2015 |
KRAS mutations affect prognosis of non-small-cell lung cancer patients treated with first-line platinum containing chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; DNA Mutational Analysis; ErbB Receptors; Female; Genotype; Humans; Italy; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Mutation; Platinum; Prognosis; Proto-Oncogene Proteins p21(ras); Treatment Outcome | 2015 |
Quality of life results from the phase 3 REVEL randomized clinical trial of ramucirumab-plus-docetaxel versus placebo-plus-docetaxel in advanced/metastatic non-small cell lung cancer patients with progression after platinum-based chemotherapy.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Docetaxel; Female; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Neoplasm Metastasis; Neoplasm Staging; Platinum; Proportional Hazards Models; Quality of Life; Ramucirumab; Retreatment; Taxoids; Treatment Outcome | 2016 |
Tumor marker analyses from the phase III, placebo-controlled, FASTACT-2 study of intercalated erlotinib with gemcitabine/platinum in the first-line treatment of advanced non-small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Erlotinib Hydrochloride; Female; Gemcitabine; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Neoplasm Staging; Platinum; Treatment Outcome | 2016 |
DNA repair gene polymorphisms in non-small-cell lung cancer patients treated with first-line platinum-containing chemotherapy.
Topics: Adult; Aged; Alleles; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; DNA Repair; Female; Gene Frequency; Genes, erbB-1; Genes, ras; Genetic Predisposition to Disease; Genotype; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Mutation; Neoplasm Staging; Platinum; Polymorphism, Single Nucleotide; Prognosis; Risk Factors | 2016 |
A randomized, double-blind, phase II study of ramucirumab plus docetaxel vs placebo plus docetaxel in Japanese patients with stage IV non-small cell lung cancer after disease progression on platinum-based therapy.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Disease Progression; Docetaxel; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Ramucirumab; Retreatment; Risk Factors; Taxoids; Treatment Outcome | 2016 |
A randomized, phase II study of gefitinib alone versus nimotuzumab plus gefitinib after platinum-based chemotherapy in advanced non-small cell lung cancer (KCSG LU12-01).
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Female; Gefitinib; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Quinazolines | 2017 |
Osimertinib or Platinum-Pemetrexed in EGFR T790M-Positive Lung Cancer.
Topics: Acrylamides; Adult; Aged; Aged, 80 and over; Aniline Compounds; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; ErbB Receptors; Female; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Pemetrexed; Piperazines; Platinum; Young Adult | 2017 |
Randomized Phase III Trial of Erlotinib versus Docetaxel in Patients with Advanced Squamous Cell Non-Small Cell Lung Cancer Failing First-Line Platinum-Based Doublet Chemotherapy Stratified by VeriStrat Good versus VeriStrat Poor. The European Thoracic On
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cohort Studies; Docetaxel; Erlotinib Hydrochloride; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Neoplasm Staging; Platinum; Prognosis; Survival Rate; Taxoids | 2017 |
Phase I and pharmacokinetic study of pemetrexed plus cisplatin in chemonaive patients with locally advanced or metastatic malignant pleural mesothelioma or non-small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Dietary Supplements; Drug Administration Schedule; Female; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Mesothelioma; Middle Aged; Pemetrexed; Platinum; Pleural Neoplasms; Vitamins | 2009 |
Polymorphisms in hMSH2 and hMLH1 and response to platinum-based chemotherapy in advanced non-small-cell lung cancer patients.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Antineoplastic Agents; Asian People; Carcinoma, Non-Small-Cell Lung; Cisplatin; Combined Modality Therapy; Drug Resistance, Neoplasm; Female; Genetic Predisposition to Disease; Humans; Lung Neoplasms; Male; Middle Aged; MutL Protein Homolog 1; MutS Homolog 2 Protein; Neoplasm Staging; Nuclear Proteins; Platinum; Polymorphism, Genetic; Polymorphism, Single Nucleotide | 2010 |
Non-platinum-based first-line followed by platinum-based second-line chemotherapy or the reverse sequence in patients with advanced non-small cell lung cancer: a retrospective analysis by the lung cancer group of the Hellenic Oncology Research Group.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Cohort Studies; Disease Progression; Female; Greece; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Retrospective Studies; Treatment Outcome | 2010 |
Long-term administration of second-line chemotherapy with S-1 and gemcitabine for platinum-resistant non-small cell lung cancer: a phase II study.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Deoxycytidine; Drug Combinations; Drug Resistance, Neoplasm; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Oxonic Acid; Platinum; Salvage Therapy; Survival Rate; Tegafur; Time Factors; Treatment Outcome | 2011 |
Cost-effectiveness of second-line chemotherapy for non-small cell lung cancer: an economic, randomized, prospective, multicenter phase III trial comparing docetaxel and pemetrexed: the GFPC 05-06 study.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Docetaxel; Female; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Pemetrexed; Platinum; Prospective Studies; Salvage Therapy; Survival Rate; Taxoids; Treatment Outcome | 2011 |
[Efficacy of salvage chemotherapy in the advanced non-small cell lung cancer patients who failed the treatment of chemotherapy and EGFR-TKI].
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Docetaxel; ErbB Receptors; Erlotinib Hydrochloride; Female; Follow-Up Studies; Gefitinib; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Neutropenia; Pemetrexed; Platinum; Protein Kinase Inhibitors; Quinazolines; Remission Induction; Salvage Therapy; Taxoids; Treatment Failure | 2010 |
Randomized phase IIIb trial evaluating the continuation of bevacizumab beyond disease progression in patients with advanced non-squamous non-small-cell lung cancer after first-line treatment with bevacizumab plus platinum-based chemotherapy: treatment rat
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Non-Small-Cell Lung; Docetaxel; Erlotinib Hydrochloride; Female; Follow-Up Studies; Glutamates; Guanine; Humans; International Agencies; Lung Neoplasms; Maintenance Chemotherapy; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Pemetrexed; Platinum; Quality of Life; Quinazolines; Survival Rate; Taxoids; Treatment Outcome; Young Adult | 2011 |
Erlotinib monotherapy for the maintenance treatment of non-small cell lung cancer after previous platinum-containing chemotherapy: a NICE single technology appraisal.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cost-Benefit Analysis; Erlotinib Hydrochloride; Guidelines as Topic; Health Care Costs; Humans; Lung Neoplasms; Models, Economic; Platinum; Quinazolines; Randomized Controlled Trials as Topic; Treatment Outcome; United Kingdom | 2011 |
[Effect of the XRCC1 and XRCC3 genetic polymorphisms on the efficacy of platinum-based chemotherapy in patients with advanced non-small cell lung cancer].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Female; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Treatment Outcome; X-ray Repair Cross Complementing Protein 1 | 2011 |
Trabectedin in patients with advanced non-small-cell lung cancer (NSCLC) with XPG and/or ERCC1 overexpression and BRCA1 underexpression and pretreated with platinum.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; BRCA1 Protein; Carcinoma, Non-Small-Cell Lung; Dioxoles; DNA-Binding Proteins; Endonucleases; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Nuclear Proteins; Platinum; Tetrahydroisoquinolines; Trabectedin; Transcription Factors; Treatment Outcome | 2012 |
A phase II study of halichondrin B analog eribulin mesylate (E7389) in patients with advanced non-small cell lung cancer previously treated with a taxane: a California cancer consortium trial.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Ethers, Cyclic; Female; Follow-Up Studies; Furans; Humans; Ketones; Lung Neoplasms; Macrolides; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Platinum; Salvage Therapy; Survival Rate; Taxoids; Treatment Outcome | 2012 |
Randomized phase 2b study of pralatrexate versus erlotinib in patients with stage IIIB/IV non-small-cell lung cancer (NSCLC) after failure of prior platinum-based therapy.
Topics: Adult; Aged; Aged, 80 and over; Aminopterin; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Dose-Response Relationship, Drug; ErbB Receptors; Erlotinib Hydrochloride; Female; Folic Acid Antagonists; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Protein Kinase Inhibitors; Quinazolines; Retrospective Studies; Survival Rate; Treatment Failure; United States | 2012 |
Pemetrexed plus platinum or gemcitabine plus platinum for advanced non-small cell lung cancer: final survival analysis from a multicentre randomized phase II trial in the East Asia region and a meta-analysis.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asia; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Female; Gemcitabine; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Middle Aged; Pemetrexed; Platinum; Survival Analysis; Treatment Outcome | 2013 |
Aflibercept and Docetaxel versus Docetaxel alone after platinum failure in patients with advanced or metastatic non-small-cell lung cancer: a randomized, controlled phase III trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Confidence Intervals; Disease-Free Survival; Docetaxel; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Maximum Tolerated Dose; Neoplasm Invasiveness; Neoplasm Staging; Platinum; Prognosis; Proportional Hazards Models; Prospective Studies; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Risk Assessment; Survival Analysis; Taxoids; Treatment Outcome | 2012 |
Phase I clinical trial of the novel platin complex dicycloplatin: clinical and pharmacokinetic results.
Topics: Adult; Aged; Anemia; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; China; Cyclobutanes; Dicarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Nausea; Neoplasms; Neutropenia; Platinum; Thrombocytopenia; Vomiting | 2013 |
Role of ERCC5 promoter polymorphisms in response to platinum-based chemotherapy in patients with advanced non-small-cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cisplatin; Confidence Intervals; DNA-Binding Proteins; Endonucleases; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nuclear Proteins; Platinum; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Transcription Factors; Transcription Initiation Site; Treatment Outcome; Young Adult | 2013 |
A phase II study of sorafenib in patients with platinum-pretreated, advanced (Stage IIIb or IV) non-small cell lung cancer with a KRAS mutation.
Topics: Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Female; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Platinum; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Sorafenib; Treatment Outcome | 2013 |
[Prospective study on surface-enhanced laser desorption/ionization protein fingerprinting for diagnosing gene polymorphism leading to drug resistance drift: sequential therapy with a platinum-based regimen and gefitinib for non-small cell lung cancer].
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Gefitinib; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Polymorphism, Genetic; Prospective Studies; Proteomics; Quinazolines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Treatment Outcome | 2013 |
Gemcitabine and vinorelbine as second-line therapy for non-small cell lung cancer after treatment with paclitaxel plus platinum.
Topics: Adult; Aftercare; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Drug Administration Schedule; Feasibility Studies; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Middle Aged; Nervous System Diseases; Neutropenia; Paclitaxel; Platinum; Survival Rate; Vinblastine; Vinorelbine | 2004 |
Phase I clinical and pharmacologic study of a 2-weekly administration of cisplatin and gemcitabine in patients with advanced non-small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carcinoma, Non-Small-Cell Lung; Cisplatin; Deoxycytidine; DNA Adducts; Dose-Response Relationship, Drug; Floxuridine; Gemcitabine; Humans; Leukocytes; Male; Middle Aged; Platinum; Treatment Outcome | 2005 |
Topotecan plus ifosfamide in patients with platinum refractory advanced/metastatic non-small cell lung cancer: a phase II trial.
Topics: Adult; Aged; Alopecia; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Drug Resistance, Neoplasm; Female; Humans; Ifosfamide; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Neutropenia; Platinum; Thrombocytopenia; Topotecan; Treatment Outcome | 2005 |
Effect of chemotherapy for advanced non-small cell lung cancer on patients' quality of life. A randomized controlled trial.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carcinoma, Non-Small-Cell Lung; Cisplatin; Docetaxel; Female; Humans; Lung Neoplasms; Male; Middle Aged; Pain; Patient Compliance; Platinum; Prospective Studies; Psychomotor Performance; Quality of Life; Sickness Impact Profile; Taxoids; Treatment Outcome; Vinblastine; Vinorelbine | 2006 |
Phase II study of combination chemotherapy with gemcitabine and irinotecan in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens.
Topics: Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Drug Administration Schedule; Female; Gemcitabine; Humans; Irinotecan; Leukopenia; Lung Neoplasms; Male; Middle Aged; Nausea; Platinum; Survival Rate | 2006 |
Phase II study of SPI-77 (sterically stabilised liposomal cisplatin) in advanced non-small-cell lung cancer.
Topics: Aged; Area Under Curve; Carcinoma, Non-Small-Cell Lung; Cisplatin; DNA Adducts; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Leukocytes; Lung Neoplasms; Male; Metabolic Clearance Rate; Middle Aged; Neoplasm Staging; Platinum; Survival Analysis; Treatment Outcome | 2006 |
Phase II study of gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), and celecoxib, a cyclooxygenase-2 (COX-2) inhibitor, in patients with platinum refractory non-small cell lung cancer (NSCLC).
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Celecoxib; Confidence Intervals; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Neoplasm; ErbB Receptors; Female; Follow-Up Studies; Gefitinib; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Platinum; Probability; Pyrazoles; Quinazolines; Risk Assessment; Sulfonamides; Survival Analysis | 2007 |
[Results of a combination of platinum-vindesin-ametycin-bleomycin (CEMB) in the treatment of stage IV non-small-cell lung cancers].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Female; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Mitomycin; Platinum; Vindesine | 1993 |
Sequential treatment with vindesine-ifosfamide-platinum (VIP) chemotherapy followed by platinum sensitized radiotherapy in stage IIIB non-small cell lung cancer: a phase II trial.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Drug Administration Schedule; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Middle Aged; Platinum; Prospective Studies; Radiation-Sensitizing Agents; Radiotherapy, Adjuvant; Survival Analysis; Treatment Outcome; Vindesine | 1998 |
Result of induction chemotherapy followed by surgery in patients with stage IIIA N2 NSCLC: importance of pre-treatment mediastinoscopy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Disease-Free Survival; Female; Humans; Ifosfamide; Lung Neoplasms; Lymphatic Metastasis; Male; Mediastinoscopy; Middle Aged; Neoplasm Staging; Platinum; Pneumonectomy; Prognosis; Prospective Studies; Remission Induction; Survival Analysis; Survival Rate; Vindesine | 1999 |
Gemcitabine and docetaxel as second-line chemotherapy for patients with nonsmall cell lung carcinoma who fail prior paclitaxel plus platinum-based regimens.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Docetaxel; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Paclitaxel; Patient Compliance; Platinum; Survival Analysis; Taxoids; Treatment Outcome | 2001 |
Influence of glutathione administration on the disposition of free and total platinum in patients after administration of cisplatin.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Drug Interactions; Drug Therapy, Combination; Etoposide; Glutathione; Half-Life; Humans; Lung Neoplasms; Mesothelioma; Platinum; Pleural Neoplasms; Time Factors | 1992 |
Effects of sodium thiosulfate in combination therapy of cis-dichlorodiammineplatinum and vindesine.
Topics: Adenocarcinoma; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Humans; Kidney; Lung Neoplasms; Platinum; Random Allocation; Thiosulfates; Time Factors; Vindesine | 1989 |
A randomized study comparing platinum, doxorubicin, and VP-16 with platinum, 4'-epidoxorubicin, and VP-16 in patients with non-small-cell lung cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Clinical Trials as Topic; Doxorubicin; Epirubicin; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Platinum; Podophyllotoxin; Random Allocation | 1987 |
250 other study(ies) available for platinum and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Successful treatment of locally advanced lung cancer using late concurrent chemoradiation therapy administered after immune checkpoint inhibitor plus platinum chemotherapy.
Topics: Carcinoma, Non-Small-Cell Lung; Chemoradiotherapy; Female; Humans; Immune Checkpoint Inhibitors; Lung Neoplasms; Male; Middle Aged; Platinum; Small Cell Lung Carcinoma | 2021 |
Heterogeneous radiological response to chemotherapy is associated with poor prognosis in advanced non-small-cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Female; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Positron Emission Tomography Computed Tomography; Prognosis; Progression-Free Survival | 2021 |
Intestinal flora characteristics of advanced non-small cell lung cancer in China and their role in chemotherapy based on metagenomics: A prospective exploratory cohort study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; China; Cohort Studies; Female; Gastrointestinal Microbiome; High-Throughput Nucleotide Sequencing; Humans; Lung Neoplasms; Male; Metagenomics; Middle Aged; Platinum; Prospective Studies | 2021 |
Ability of the Glasgow Prognostic Score to predict the tolerability and efficacy of platinum-combination chemotherapy among elderly patients with advanced non-small cell lung cancer.
Topics: Aged; Carcinoma, Non-Small-Cell Lung; Drug Therapy, Combination; Humans; Lung Neoplasms; Platinum; Prognosis; Retrospective Studies | 2021 |
Clinical outcomes in stage III non-small cell lung cancer patients treated with durvalumab after sequential or concurrent platinum-based chemoradiotherapy - single institute experience.
Topics: Antibodies, Monoclonal; Carcinoma, Non-Small-Cell Lung; Chemoradiotherapy; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Retrospective Studies; Treatment Outcome | 2021 |
Effects of Shenmai injection combined with platinum-containing first-line chemotherapy on quality of life, immune function and prognosis of patients with nonsmall cell lung cancer: A protocol for systematic review and meta-analysis.
Topics: Carcinoma, Non-Small-Cell Lung; Drug Combinations; Drugs, Chinese Herbal; Humans; Immunity; Lung Neoplasms; Meta-Analysis as Topic; Platinum; Prognosis; Quality of Life; Research Design; Systematic Reviews as Topic | 2021 |
Chemotherapy Plus Immunotherapy Versus Chemotherapy Plus Bevacizumab Versus Chemotherapy Alone in EGFR-Mutant NSCLC After Progression on Osimertinib.
Topics: Acrylamides; Aniline Compounds; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Humans; Immunotherapy; Lung Neoplasms; Mutation; Platinum; Retrospective Studies | 2022 |
Association of the Geriatric Nutritional Risk Index with the survival of patients with non-small-cell lung cancer after platinum-based chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Albumins; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cisplatin; Female; Geriatric Assessment; Humans; Japan; Lung Neoplasms; Male; Middle Aged; Nutrition Assessment; Platinum; Retrospective Studies; Risk Factors; Survival Rate | 2021 |
Transcriptomics reveals
Topics: Adenosine Diphosphate; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cholesterol; Cisplatin; Humans; Integrins; Lung Neoplasms; Platinum; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Ribose; Transcriptome; Transforming Growth Factor beta | 2022 |
dNLR-Based Score Predicting Overall Survival Benefit for The Addition of Platinum-Based Chemotherapy to Pembrolizumab in Advanced NSCLC With PD-L1 Tumor Proportion Score ≥50.
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Disease Progression; Female; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Retrospective Studies; Treatment Outcome | 2022 |
Platinum Re-Exposure as a Non-Small Cell Lung Cancer (NSCLC) Treatment Strategy in the Age of Immunotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Humans; Immunotherapy; Lung Neoplasms; Platinum; Retrospective Studies | 2022 |
FDA Approval Summary: Pembrolizumab, Atezolizumab, and Cemiplimab-rwlc as Single Agents for First-Line Treatment of Advanced/Metastatic PD-L1-High NSCLC.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Platinum; United States | 2022 |
Switch to EGFR-TKI after upfront platinum doublet induction therapy in non-small cell lung cancer (NSCLC) patients with EGFR (Epidermal Growth Factor Receptor) mutation: A multicentre retrospective study.
Topics: Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Humans; Induction Chemotherapy; Lung Neoplasms; Mutation; Platinum; Protein Kinase Inhibitors; Retrospective Studies | 2022 |
Sintilimab with chemotherapy as first-line treatment for locally advanced or metastatic squamous non-small-cell lung cancer: a real-world data study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Gemcitabine; Humans; Lung Neoplasms; Paclitaxel; Platinum; Prospective Studies; Retrospective Studies | 2023 |
VEGF single nucleotide polymorphisms predict improved outcome in advanced non-small cell lung cancer patients treated with platinum-based chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Genotype; Humans; Lung Neoplasms; Platinum; Polymorphism, Single Nucleotide; Vascular Endothelial Growth Factor A | 2023 |
Comparative survival analysis of platinum-based adjuvant chemotherapy for early-stage squamous cell carcinoma and adenocarcinoma of the lung.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Humans; Lung; Lung Neoplasms; Neoplasm Staging; Platinum; Survival Analysis | 2022 |
Bevacizumab in combination with pemetrexed and platinum for elderly patients with advanced non-squamous non-small-cell lung cancer: a retrospective analysis.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Pemetrexed; Platinum; Retrospective Studies; Treatment Outcome | 2022 |
Association of variations in the Fanconi anemia complementation group and prognosis in Non-small cell lung cancer patients with Platinum-based chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Fanconi Anemia; Female; Genotype; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Polymorphism, Single Nucleotide | 2022 |
The endocytosis of nano-Pt into non-small cell lung cancer H1299 cells and intravital therapeutic effect in vivo.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Endocytosis; Humans; Lung Neoplasms; Mice; Platinum | 2022 |
Efficacy of platinum agents for stage III non-small-cell lung cancer following platinum-based chemoradiotherapy: a retrospective study.
Topics: Carcinoma, Non-Small-Cell Lung; Chemoradiotherapy; Female; Humans; Lung Neoplasms; Neoplasm Recurrence, Local; Platinum; Retrospective Studies | 2022 |
The prevalence and real-world therapeutic analysis of Chinese patients with KRAS-Mutant Non-Small Cell lung cancer.
Topics: Bevacizumab; Carcinoma, Non-Small-Cell Lung; China; ErbB Receptors; Humans; Immune Checkpoint Inhibitors; Kelch-Like ECH-Associated Protein 1; Lung Neoplasms; Mutation; NF-E2-Related Factor 2; Pemetrexed; Platinum; Prevalence; Proto-Oncogene Proteins p21(ras); Retrospective Studies; Taxoids | 2022 |
Clinical efficacy and safety of pemetrexed with or without either Bevacizumab or Pembrolizumab in patients with metastatic nonsquamous non-small cell carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carboplatin; Carcinoma; Carcinoma, Non-Small-Cell Lung; Cohort Studies; Humans; Lung Neoplasms; Pemetrexed; Platinum; Retrospective Studies; Treatment Outcome | 2023 |
How platinum-induced nephrotoxicity occurs? Machine learning prediction in non-small cell lung cancer patients.
Topics: Carcinoma, Non-Small-Cell Lung; Drug-Related Side Effects and Adverse Reactions; Humans; Lung Neoplasms; Machine Learning; Platinum | 2022 |
Activin-A, Growth Differentiation Factor-11 and Transforming Growth Factor-β as predictive biomarkers for platinum chemotherapy in advanced non-small cell lung cancer.
Topics: Activins; Adult; Biomarkers; Bone Morphogenetic Proteins; Carcinoma, Non-Small-Cell Lung; Growth Differentiation Factors; Humans; Lung Neoplasms; Organoplatinum Compounds; Platinum; Prospective Studies; Retrospective Studies; Transforming Growth Factor beta; Transforming Growth Factors | 2022 |
Amivantamab compared with real-world therapies in patients with advanced non-small cell lung cancer harboring EGFR exon 20 insertion mutations who progressed after platinum-based chemotherapy.
Topics: Antibodies, Bispecific; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Exons; Humans; Lung Neoplasms; Mutagenesis, Insertional; Mutation; Platinum; Protein Kinase Inhibitors | 2022 |
The impact of TP53 co-mutations and immunologic microenvironment on outcome of lung cancer with EGFR exon 20 insertions.
Topics: Antineoplastic Agents; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Exons; Humans; Lung Neoplasms; Mutation; Platinum; Protein Kinase Inhibitors; Retrospective Studies; Tumor Microenvironment; Tumor Suppressor Protein p53 | 2022 |
Efficacy and safety of maintenance immune checkpoint inhibitors with or without pemetrexed in advanced non-squamous non-small cell lung cancer: a retrospective study.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Humans; Immune Checkpoint Inhibitors; Lung Neoplasms; Pemetrexed; Platinum; Retrospective Studies | 2022 |
Real-world treatment pattern and comprehensive comparative effectiveness of Endostar plus different chemotherapy in advanced patients with non-small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Endostatins; Humans; Lung Neoplasms; Pemetrexed; Platinum; Recombinant Proteins | 2022 |
Computed Tomography Image under Artificial Intelligence Algorithm to Evaluate the Nursing and Treatment Effect of Pemetrexed Combined Platinum-Based Chemotherapy on Elderly Lung Cancer.
Topics: Aged; Antigens, Neoplasm; Artificial Intelligence; Carcinoma, Non-Small-Cell Lung; Cisplatin; Docetaxel; Humans; Keratin-19; Lung Neoplasms; Pemetrexed; Platinum; Tomography; Tomography, X-Ray Computed | 2022 |
Pembrolizumab for the better treatment of EGFR-mutant T790M-negative advanced lung adenocarcinoma patients than dual treatment of pemetrexed plus platinum after tyrosine kinase inhibitor treatment failure.
Topics: Adenocarcinoma of Lung; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Female; Humans; Lung Neoplasms; Mutation; Pemetrexed; Platinum; Prospective Studies; Protein Kinase Inhibitors; Treatment Failure | 2022 |
Does Molecular Profiling of
Topics: B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Pemetrexed; Platinum; Proto-Oncogene Proteins p21(ras) | 2022 |
Study on the Predictive Value of P53 Protein Expression in Brain Metastasis in NSCLC and the Mechanism of miR-424 Reversing Platinum Resistance in NSCLC.
Topics: Biomarkers, Tumor; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; MicroRNAs; Platinum; Retrospective Studies; Tumor Suppressor Protein p53 | 2022 |
A miR-15a related polymorphism affects NSCLC prognosis via altering ERCC1 repair to platinum-based chemotherapy.
Topics: 3' Untranslated Regions; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Endonucleases; Humans; Lung Neoplasms; MicroRNAs; Platinum; Polymorphism, Single Nucleotide | 2022 |
Efficacy, safety, and prognostic factors of apatinib plus platinum doublet chemotherapy in advanced non-small cell lung cancer.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Middle Aged; Platinum; Prognosis; Pyridines; Retrospective Studies; Vascular Endothelial Growth Factor Receptor-2 | 2022 |
Immunotherapy and Prognosis of Non-small Cell Lung Carcinoma by Monomethoxy polyethylene glycol-hyaluronic acid-platinum Combined with Immune CT4+ and CT8+ Detection.
Topics: Carcinoma, Non-Small-Cell Lung; Humans; Hyaluronic Acid; Immunotherapy; Lung Neoplasms; Platinum; Polyethylene Glycols | 2022 |
Prevalence, Treatment Patterns, and Outcomes of Individuals with
Topics: Afatinib; Alberta; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Erlotinib Hydrochloride; Exons; Gefitinib; Humans; Lung Neoplasms; Mutation; Platinum; Prevalence | 2022 |
A single center analysis of first-line treatment in advanced KRAS mutant non-small cell lung cancer: real-world practice.
Topics: Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Disease Progression; Humans; Lung Neoplasms; Pemetrexed; Platinum; Proto-Oncogene Proteins p21(ras) | 2022 |
[Neoadjuvant nivolumab in combination with platinum-based chemotherapy for operable lung cancer].
Topics: Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Neoadjuvant Therapy; Nivolumab; Platinum | 2023 |
Zebrafish patient-derived xenografts accurately and quickly reproduce treatment outcomes in non-small cell lung cancer patients.
Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Docetaxel; ErbB Receptors; Heterografts; Humans; Lung Neoplasms; Mutation; Platinum; Protein Kinase Inhibitors; Treatment Outcome; Zebrafish | 2023 |
Lorlatinib beyond progression plus platinum/pemetrexed for ALK-positive non-small cell lung cancer patients: report of two cases.
Topics: Anaplastic Lymphoma Kinase; Carcinoma, Non-Small-Cell Lung; Humans; Lactams, Macrocyclic; Lung Neoplasms; Pemetrexed; Platinum; Protein Kinase Inhibitors | 2023 |
Association between Genetic Variants and Peripheral Neuropathy in Patients with NSCLC Treated with First-Line Platinum-Based Therapy.
Topics: Carcinoma, Non-Small-Cell Lung; Follow-Up Studies; Humans; Lung Neoplasms; Peripheral Nervous System Diseases; Platinum; Prospective Studies | 2023 |
Real-world multicentre cohort of first-line pembrolizumab alone or in combination with platinum-based chemotherapy in non-small cell lung cancer PD-L1 ≥ 50.
Topics: Antineoplastic Agents, Immunological; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Male; Platinum; Retrospective Studies | 2023 |
A prognostic baseline blood biomarker and tumor growth kinetics integrated model in paclitaxel/platinum treated advanced non-small cell lung cancer patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Paclitaxel; Platinum; Prognosis | 2023 |
[Drug approval: ATEZOLIZUMAB as monotherapy in NSCLC PD-L1 ≥ 50%, without EGFR mutation or ALK rearrangement, for adjuvant treatment after complete surgery and platinum-based chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Drug Approval; ErbB Receptors; Humans; Lung Neoplasms; Mutation; Platinum; Receptor Protein-Tyrosine Kinases | 2023 |
A Non-Conventional Platinum Drug against a Non-Small Cell Lung Cancer Line.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Humans; Lung Neoplasms; Platinum | 2023 |
A Multicenter Retrospective Chart Review of Clinical Outcomes Among Patients With KRAS G12C Mutant Non-Small Cell Lung Cancer.
Topics: Carcinoma, Non-Small-Cell Lung; Docetaxel; Humans; Kelch-Like ECH-Associated Protein 1; Lung Neoplasms; Mutation; Neoplasm Recurrence, Local; NF-E2-Related Factor 2; Platinum; Proto-Oncogene Proteins p21(ras); Retrospective Studies; Taxoids | 2023 |
Multicentre real-world data of ramucirumab plus docetaxel after combined platinum-based chemotherapy with programmed death-1 blockade in advanced non-small cell lung cancer: NEJ051 (REACTIVE study).
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Docetaxel; Female; Humans; Lung Neoplasms; Male; Platinum; Ramucirumab; Retrospective Studies; Taxoids | 2023 |
Disulfiram enhances cisplatin cytotoxicity by forming a novel platinum chelate Pt(DDTC)
Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disulfiram; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; Mice; Platinum | 2023 |
Cellular immunotherapy combined with platinum-based chemotherapy prolongs survival for non-small cell lung cancer patients.
Topics: Carcinoma, Non-Small-Cell Lung; Humans; Immunotherapy; Lung Neoplasms; Platinum; Retrospective Studies | 2023 |
Clinical benefit of platinum doublet combination therapy in older adults with advanced non-small cell lung cancer: A prospective multicenter study by the National Hospital Organization in Japan.
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Hospitals; Humans; Japan; Lung Neoplasms; Platinum; Prospective Studies | 2023 |
Comparative effectiveness of mobocertinib and standard of care in patients with NSCLC with EGFR exon 20 insertion mutations: An indirect comparison.
Topics: Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Exons; Humans; Lung Neoplasms; Mutagenesis, Insertional; Mutation; Platinum; Protein Kinase Inhibitors; Standard of Care | 2023 |
US Food and Drug Administration Approval Summary: Nivolumab Plus Platinum-Doublet Chemotherapy for the Neoadjuvant Treatment of Patients With Resectable Non-Small-Cell Lung Cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Humans; Ipilimumab; Lung Neoplasms; Neoadjuvant Therapy; Nivolumab; Platinum; United States; United States Food and Drug Administration | 2023 |
Association of Antifolate Response Signature Status and Clinical Activity of Pemetrexed-Platinum Chemotherapy in Non-Small Cell Lung Cancer: The Piedmont Study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Folic Acid Antagonists; Humans; Lung Neoplasms; Pemetrexed; Platinum; Retrospective Studies | 2023 |
Nano-Pt induced mitochondria-dependent apoptosis and cytoprotective autophagy in human NSCLC cells.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Mitochondria; Platinum | 2023 |
Characteristics, treatment patterns, and clinical outcomes in patients with advanced non-small cell lung cancer harboring EGFR exon 20 insertions.
Topics: Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Exons; Humans; Lung Neoplasms; Male; Mutation; Neoplasm Recurrence, Local; Platinum; Protein Kinase Inhibitors; Retrospective Studies | 2023 |
Platinum-combination chemotherapy with or without immune-checkpoint inhibitor in patients with postoperative recurrent non-small cell lung cancer previously treated with adjuvant platinum-doublet chemotherapy: A multicenter retrospective study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Humans; Immune Checkpoint Inhibitors; Lung Neoplasms; Neoplasm Recurrence, Local; Platinum; Retrospective Studies | 2023 |
Atezolizumab in patients with advanced non-small-cell lung cancer who are platinum-doublet ineligible.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Platinum | 2023 |
Thrombotic risk of platinum combination chemotherapy with and without immune checkpoint inhibitors for advanced non-small cell lung cancer: a nationwide inpatient database study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Humans; Immune Checkpoint Inhibitors; Inpatients; Lung Neoplasms; Platinum; Retrospective Studies; Thrombosis; Venous Thromboembolism | 2023 |
Real-World Data About Treatment Outcomes for Patients with EGFR-Mutated NSCLC Resistance to Osimertinib and Platinum-Based Chemotherapy.
Topics: Carcinoma, Non-Small-Cell Lung; Docetaxel; ErbB Receptors; Genes, erbB-1; Humans; Lung Neoplasms; Middle Aged; Mutation; Platinum; Protein Kinase Inhibitors; Treatment Outcome | 2023 |
Outcomes of Combination Platinum-Doublet Chemotherapy and Anti-PD(L)-1 Blockade in KRASG12C-Mutant Non-Small Cell Lung Cancer.
Topics: Carcinoma, Non-Small-Cell Lung; Humans; Kelch-Like ECH-Associated Protein 1; Lung Neoplasms; NF-E2-Related Factor 2; Platinum; Protein Serine-Threonine Kinases | 2023 |
CRTAC1 enhances the chemosensitivity of non-small cell lung cancer to cisplatin by eliciting RyR-mediated calcium release and inhibiting Akt1 expression.
Topics: Animals; Calcium; Carcinoma, Non-Small-Cell Lung; Cisplatin; Humans; Lung Neoplasms; Mice; Platinum | 2023 |
Efficacy of paclitaxel-carboplatin with bevacizumab as a late-line therapy for patients with advanced nonsquamous non-small cell lung cancer: A platinum rechallenge.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carboplatin; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Paclitaxel; Platinum; Retrospective Studies | 2023 |
Current and Emerging Treatment Options for Patients with Metastatic EGFR-Mutated Non-small Cell Lung Cancer After Progression on Osimertinib and Platinum-Based Chemotherapy: A Podcast Discussion.
Topics: Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Humans; Lung Neoplasms; Mutation; Platinum; Protein Kinase Inhibitors | 2023 |
Cost-effectiveness analysis of atezolizumab in patients with non-small-cell lung cancer ineligible for treatment with a platinum-containing regimen: a United Kingdom health care perspective.
Topics: Carcinoma, Non-Small-Cell Lung; Cost-Benefit Analysis; Cost-Effectiveness Analysis; Delivery of Health Care; Humans; Lung Neoplasms; Platinum; Reproducibility of Results | 2023 |
Cost-Effectiveness Analysis of Atezolizumab versus Platinum-Based Chemotherapy as First-Line Treatment for Patients with Unresectable Advanced Non-small Cell Lung Cancer with PD-L1 Expression Status in Japan.
Topics: Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Cost-Benefit Analysis; Cost-Effectiveness Analysis; Humans; Japan; Lung Neoplasms; Platinum; Quality-Adjusted Life Years | 2023 |
DNA damage response and repair gene mutations are associated with tumor mutational burden and outcomes to platinum-based chemotherapy/immunotherapy in advanced NSCLC patients.
Topics: Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; DNA Damage; ErbB Receptors; Humans; Immunotherapy; Lung Neoplasms; Mutation; Platinum; Receptor Protein-Tyrosine Kinases | 2023 |
Amivantamab compared with real-world therapies in patients with advanced non-small cell lung cancer
Topics: Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Exons; Humans; Lung Neoplasms; Mutagenesis, Insertional; Mutation; Platinum; Protein Kinase Inhibitors | 2023 |
IPSOS trial: A "game changer" redefining first-line immunotherapy in platinum-ineligible NSCLC.
Topics: Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Humans; Immunotherapy; Lung Neoplasms; Platinum | 2023 |
Functional outcomes and survival after surgical stabilization for inoperable non-small-cell lung cancer with spinal metastasis of the thoracic and lumbar spines: a retrospective comparison between epidermal growth factor receptor-tyrosine kinase inhibitor
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; ErbB Receptors; Female; Humans; Lumbar Vertebrae; Lung Neoplasms; Male; Middle Aged; Orthopedic Procedures; Outcome Assessment, Health Care; Platinum; Protein Kinase Inhibitors; Retrospective Studies; Spinal Neoplasms; Thoracic Vertebrae | 2020 |
Homologous recombination in lung cancer, germline and somatic mutations, clinical and phenotype characterization.
Topics: Adenocarcinoma of Lung; Aged; Biomarkers, Tumor; BRCA1 Protein; BRCA2 Protein; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Fanconi Anemia Complementation Group N Protein; Female; Follow-Up Studies; Germ-Line Mutation; Homologous Recombination; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Platinum; Prognosis; Retrospective Studies; Survival Rate | 2019 |
First-line platinum-based chemotherapy and survival outcomes in locally advanced or metastatic pulmonary lymphoepithelioma-like carcinoma.
Topics: Adenocarcinoma of Lung; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemoradiotherapy; Deoxycytidine; Female; Follow-Up Studies; Gemcitabine; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Platinum; Prognosis; Retrospective Studies; Survival Rate; Taxoids | 2019 |
Model-Based Economic Evaluation of Ceritinib and Platinum-Based Chemotherapy as First-Line Treatments for Advanced Non-Small Cell Lung Cancer in China.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; China; Cost-Benefit Analysis; Disease-Free Survival; Humans; Lung Neoplasms; Models, Economic; Platinum; Pyrimidines; Quality-Adjusted Life Years; Sulfones | 2019 |
Elevated Circulating Activin A Levels in Patients With Malignant Pleural Mesothelioma Are Related to Cancer Cachexia and Reduced Response to Platinum-based Chemotherapy.
Topics: Activins; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cachexia; Carcinoma, Non-Small-Cell Lung; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Mesothelioma, Malignant; Middle Aged; Platinum; Pleural Neoplasms; Prognosis; Prospective Studies; Retrospective Studies; ROC Curve | 2020 |
Programmed co-delivery of platinum nanodrugs and gemcitabine by a clustered nanocarrier for precision chemotherapy for NSCLC tumors.
Topics: A549 Cells; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Drug Carriers; Drug Liberation; Gemcitabine; Humans; Lung Neoplasms; Metal Nanoparticles; Platinum | 2020 |
Concomitant genomic alterations in KRAS mutant advanced lung adenocarcinoma.
Topics: Adenocarcinoma of Lung; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Cohort Studies; Follow-Up Studies; Genomics; High-Throughput Nucleotide Sequencing; Humans; Lung Neoplasms; Mutation; Platinum; Prognosis; Proto-Oncogene Proteins p21(ras); Survival Rate | 2020 |
[Meta-analysis of Cinobufacini Injection combined with platinum-contained first-line chemotherapy in treatment of non-small cell lung cancer].
Topics: Amphibian Venoms; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Male; Platinum; Quality of Life | 2019 |
Is Gefitinib Combined With Platinum-Doublet Chemotherapy a Counterpart to Osimertinib Monotherapy in Advanced
Topics: Acrylamides; Aniline Compounds; Carboplatin; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Pemetrexed; Platinum | 2020 |
Clinical factors associated with treatment toxicity of pemetrexed plus platinum in elderly patients with non-small cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Pemetrexed; Platinum; Treatment Outcome | 2020 |
Healthcare resource utilization in advanced non-small-cell lung cancer: post hoc analysis of the randomized phase 3 REVEL study.
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase III as Topic; Disease Progression; Docetaxel; Female; Granulocyte Colony-Stimulating Factor; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Patient Acceptance of Health Care; Platinum; Ramucirumab; Taxoids | 2021 |
The USP10-HDAC6 axis confers cisplatin resistance in non-small cell lung cancer lacking wild-type p53.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histone Deacetylase 6; Humans; Lung Neoplasms; Mice, SCID; Mutation; Ovarian Neoplasms; Platinum; Protein Binding; Protein Stability; Signal Transduction; Substrate Specificity; Tumor Suppressor Protein p53; Ubiquitin Thiolesterase; Ubiquitination; Xenograft Model Antitumor Assays | 2020 |
The prognostic value of prognostic nutritional index (PNI) and neutrophil to lymphocyte ratio (NLR) for advanced non-small cell lung cancer treated with platinum-based chemotherapeutics.
Topics: Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Lymphocytes; Neutrophils; Nutrition Assessment; Platinum; Prognosis; Retrospective Studies | 2020 |
Anlotinib or platinum-pemetrexed as second-line therapy in EGFR T790M-negative lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Humans; Indoles; Lung Neoplasms; Mutation; Pemetrexed; Platinum; Protein Kinase Inhibitors; Quinolines; Retrospective Studies | 2020 |
Fibrosis or Necrosis in Resected Lymph Node Indicate Metastasis Before Chemoradiotherapy in Lung Cancer Patients.
Topics: Aged; Carcinoma, Non-Small-Cell Lung; Chemoradiotherapy; Female; Fibrosis; Humans; Lung Neoplasms; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Necrosis; Neoplasm Staging; Platinum; Tomography, X-Ray Computed | 2020 |
Cost-effectiveness analysis of pembrolizumab plus standard chemotherapy versus chemotherapy alone for first-line treatment of metastatic non-squamous non-small-cell lung cancer in China.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cost-Benefit Analysis; Humans; Lung Neoplasms; Pemetrexed; Platinum | 2022 |
The clinicopathological and prognostic implications of tyrosine phosphatase SHP2 and ankyrin Hook1 gene expression in non- small cell lung cancer patients treated with gemcitabine plus platinum as first-line chemotherapy.
Topics: Ankyrins; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Gemcitabine; Gene Expression; Humans; Lung Neoplasms; Neoplasm Staging; Platinum; Prognosis; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Small Cell Lung Carcinoma; Tyrosine | 2020 |
Discovery of a Chiral DNA-Targeted Platinum-Acridine Agent with Potent Enantioselective Anticancer Activity.
Topics: Acridines; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coordination Complexes; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Molecular Structure; Platinum; Stereoisomerism; Structure-Activity Relationship | 2020 |
Complete response with anti-PD-L1 antibody following progression on anti-PD-1 antibody in advanced non-small cell lung cancer.
Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Disease Progression; Humans; Lung Neoplasms; Male; Nivolumab; Platinum | 2020 |
Genetic polymorphisms of GSTP1, XRCC1, XPC and ERCC1: prediction of clinical outcome of platinum-based chemotherapy in advanced non-small cell lung cancer patients of Bangladesh.
Topics: Bangladesh; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Endonucleases; Female; Glutathione S-Transferase pi; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Proteins; Platinum; Polymorphism, Single Nucleotide; Predictive Value of Tests; X-ray Repair Cross Complementing Protein 1 | 2020 |
Circulating T-cell Immunosenescence in Patients with Advanced Non-small Cell Lung Cancer Treated with Single-agent PD-1/PD-L1 Inhibitors or Platinum-based Chemotherapy.
Topics: B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; CD8-Positive T-Lymphocytes; Humans; Immune Checkpoint Inhibitors; Immunosenescence; Immunotherapy; Lung Neoplasms; Platinum; Programmed Cell Death 1 Receptor | 2021 |
Genetic variants as predictors of toxicity and response in patients with non-small cell lung cancer undergoing first-line platinum-based chemotherapy: Design of the multicenter PGxLUNG study.
Topics: Carcinoma, Non-Small-Cell Lung; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Pharmacogenomic Variants; Platinum; Prospective Studies | 2020 |
Effect of Nano-Platinum on Proliferation and Apoptosis of Non-Small Cell Lung Cancer Cells via P53 Pathway.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; Nanoparticles; Platinum; Tumor Suppressor Protein p53 | 2021 |
Plasma levels of platinum-induced fatty acid [16:4n-3] do not affect response to platinum-based chemotherapy: A pilot study in non-small cell lung cancer patients.
Topics: Carcinoma, Non-Small-Cell Lung; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids; Humans; Lung Neoplasms; Pilot Projects; Platinum; Retrospective Studies; Tandem Mass Spectrometry | 2020 |
Real-World Effectiveness of Nivolumab Monotherapy After Prior Systemic Therapy in Advanced Non-Small-Cell Lung Cancer in the United States.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Nivolumab; Platinum; Prognosis; Retrospective Studies; Survival Rate; United States | 2021 |
Senescent T Cells as a Resistance Mechanism to Lung Cancer Immunotherapy.
Topics: Carcinoma, Non-Small-Cell Lung; Humans; Immune Checkpoint Inhibitors; Immunosenescence; Immunotherapy; Lung Neoplasms; Platinum; Programmed Cell Death 1 Receptor; T-Lymphocytes | 2021 |
RNA-Seq Analysis of Cisplatin and the Monofunctional Platinum(II) Complex, Phenanthriplatin, in A549 Non-Small Cell Lung Cancer and IMR90 Lung Fibroblast Cell Lines.
Topics: Activating Transcription Factor 3; Carcinoma, Non-Small-Cell Lung; Cell Line; Cisplatin; Coordination Complexes; Down-Regulation; Fibroblasts; Humans; Lung; Lung Neoplasms; Organoplatinum Compounds; Phenanthridines; Phosphofructokinase-2; Platinum; Sequence Analysis, RNA; Up-Regulation | 2020 |
Single-arm, open label prospective trial to assess prediction of the role of ERCC1/XPF complex in the response of advanced NSCLC patients to platinum-based chemotherapy.
Topics: Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Endonucleases; Humans; Lung Neoplasms; Platinum; Prospective Studies | 2021 |
Pembrolizumab as a monotherapy or in combination with platinum-based chemotherapy in advanced non-small cell lung cancer with PD-L1 tumor proportion score (TPS) ≥50%: real-world data.
Topics: Antibodies, Monoclonal, Humanized; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Female; Humans; In Situ Hybridization, Fluorescence; Lung Neoplasms; Platinum; Prospective Studies; Proto-Oncogene Mas; Proto-Oncogene Proteins | 2021 |
Cytidine deaminase 435C>T polymorphism relates to gemcitabine-platinum efficacy and hematological toxicity in Chinese non-small-cell lung cancer patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; China; Cytidine Deaminase; Deoxycytidine; Gemcitabine; Humans; Lung Neoplasms; Platinum; Polymorphism, Single Nucleotide | 2021 |
Neoadjuvant treatment of pembrolizumab plus platinum-doublet chemotherapy in stage IIIA squamous cell carcinoma of the lung: a case report.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Humans; Lung; Lung Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Platinum | 2021 |
Cost-effectiveness of Nivolumab-Ipilimumab Combination Therapy for the Treatment of Advanced Non-Small Cell Lung Cancer.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cost-Benefit Analysis; Drug Therapy, Combination; Female; Humans; Immune Checkpoint Inhibitors; Ipilimumab; Lung Neoplasms; Male; Nivolumab; Platinum; Quality-Adjusted Life Years; Treatment Outcome; United States | 2021 |
ERCC1 Is a Predictive Biomarker for Non-small Cell Lung Cancer But Is Antibody-dependent.
Topics: Aged; Aged, 80 and over; Antibodies, Anti-Idiotypic; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Endonucleases; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Platinum | 2021 |
Hollow PtCo alloy nanospheres as a high-
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Catalase; Cell Line, Tumor; Cobalt; Humans; Lung Neoplasms; Metal Nanoparticles; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Nanospheres; Oxygen; Platinum; Powder Diffraction; Xenograft Model Antitumor Assays | 2021 |
The role of angiotensin-(1-7) on acquired platinum resistance-induced angiogenesis in non-small cell lung cancer in vitro and in vivo.
Topics: Angiotensin I; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Peptide Fragments; Phosphatidylinositol 3-Kinases; Platinum; Vascular Endothelial Growth Factor A | 2021 |
Polymorphisms in
Topics: Aged; Carcinoma, Non-Small-Cell Lung; Chemoradiotherapy; Disease-Free Survival; ErbB Receptors; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Proteins; Platinum; Polymorphism, Single Nucleotide; Survival Rate | 2021 |
Effect of renin-angiotensin system inhibitors on pemetrexed plus platinum-induced hematological toxicities: a multicenter retrospective study using three propensity score analyses.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Pemetrexed; Platinum; Propensity Score; Renin-Angiotensin System; Retrospective Studies | 2021 |
Distinguishable Targeting of Non-Small Cell Lung Cancer Using Hyaluronan Functionalized Platinum Nanoclusters and Their Inhibition Behaviors of Proliferation, Invasion, Migration.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Hyaluronan Receptors; Hyaluronic Acid; Lung Neoplasms; Metal Nanoparticles; Platinum | 2021 |
EGFR exon 20 Insertion NSCLC and Response to Platinum-Based Chemotherapy.
Topics: Carcinoma, Non-Small-Cell Lung; Drug Resistance, Neoplasm; ErbB Receptors; Follow-Up Studies; Humans; Lung Neoplasms; Mutation; Neoplasm Staging; Platinum; Retrospective Studies; Treatment Outcome | 2022 |
More valuable than platinum: first-line pembrolizumab in advanced stage non-small-cell lung cancer.
Topics: Antibodies, Monoclonal, Humanized; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Platinum | 2017 |
Prognostic significance of nestin expression in patients with resected non-small cell lung cancer treated with platinum-based adjuvant chemotherapy; relationship between nestin expression and epithelial to mesenchymal transition related markers.
Topics: Adult; Aged; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Middle Aged; Neoplasm Staging; Nestin; Platinum; Prognosis | 2017 |
Post-Progression Survival Associated with Overall Survival in Patients with Advanced Non-Small-Cell Lung Cancer Receiving Docetaxel Monotherapy as Second-Line Chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free Survival; Docetaxel; Drug Therapy, Combination; Female; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Proportional Hazards Models; Taxoids | 2017 |
NOTCH1 Signaling Regulates Self-Renewal and Platinum Chemoresistance of Cancer Stem-like Cells in Human Non-Small Cell Lung Cancer.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Mice; Neoplastic Stem Cells; Platinum; Receptor, Notch1; Signal Transduction | 2017 |
Association between polymorphisms of autophagy pathway and responses in non-small cell lung cancer patients treated with platinum-based chemotherapy.
Topics: Adult; Aged; Autophagy; Autophagy-Related Protein-1 Homolog; Autophagy-Related Proteins; Carcinoma, Non-Small-Cell Lung; Female; Genotype; Humans; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Middle Aged; Platinum; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Ubiquitin-Conjugating Enzymes; Vesicular Transport Proteins | 2017 |
Effect of GSTP1 and ABCC2 Polymorphisms on Treatment Response in Patients with Advanced Non-Small Cell Lung Cancer Undergoing Platinum-Based Chemotherapy: A Study in a Chinese Uygur Population.
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; China; Cisplatin; Disease-Free Survival; Ethnicity; Female; Glutathione S-Transferase pi; Humans; Lung Neoplasms; Male; Middle Aged; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Platinum; Polymorphism, Single Nucleotide; Prognosis; Treatment Outcome | 2017 |
Confused reference in the article entitle: pharmacogenomics of platinum-based chemotherapy in non-small cell lung cancer-focusing on DNA repair systems.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; DNA Repair; Humans; Lung Neoplasms; Pharmacogenetics; Platinum; Polymorphism, Single Nucleotide | 2017 |
Impact of platinum/pemetrexed combination versus other platinum-based regimens on adjuvant chemotherapy in resected lung adenocarcinoma.
Topics: Adenocarcinoma of Lung; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Deoxycytidine; Disease-Free Survival; Female; Gemcitabine; Humans; Leukopenia; Male; Middle Aged; Neutropenia; Pemetrexed; Platinum; Retrospective Studies; Taxoids | 2017 |
Gene-gene and gene-environment interactions influence platinum-based chemotherapy response and toxicity in non-small cell lung cancer patients.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Doxorubicin; Epistasis, Genetic; Female; Gene-Environment Interaction; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Reproducibility of Results | 2017 |
Role of Various Metabolic Parameters Derived From Baseline 18F-FDG PET/CT as Prognostic Markers in Non-Small Cell Lung Cancer Patients Undergoing Platinum-Based Chemotherapy.
Topics: Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Female; Fluorodeoxyglucose F18; Glycolysis; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Positron Emission Tomography Computed Tomography; Prognosis; Retrospective Studies; Tumor Burden | 2018 |
Circulating metabolite profiles to predict overall survival in advanced non-small cell lung cancer patients receiving first-line chemotherapy.
Topics: Aged; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Female; Humans; Lung Neoplasms; Male; Metabolomics; Middle Aged; Neoplasm Staging; Platinum; Predictive Value of Tests; Prognosis | 2017 |
Feasibility Trial of Oral UFT after Platinum-based Adjuvant Chemotherapy in Patients with Resected Non-small Cell Lung Cancer.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Feasibility Studies; Female; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Tegafur; Uracil | 2017 |
Crizotinib in patients with anaplastic lymphoma kinase-positive advanced non-small cell lung cancer versus chemotherapy as a first-line treatment.
Topics: Adult; Aged; Anaplastic Lymphoma Kinase; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Crizotinib; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Pemetrexed; Platinum; Prognosis; Pyrazoles; Pyridines; Receptor Protein-Tyrosine Kinases; Survival Rate; Young Adult | 2018 |
FePt-Cys nanoparticles induce ROS-dependent cell toxicity, and enhance chemo-radiation sensitivity of NSCLC cells in vivo and in vitro.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Survival; Chemoradiotherapy; Cisplatin; Cysteine; Humans; Lung Neoplasms; Magnetite Nanoparticles; Platinum; Reactive Oxygen Species; Treatment Outcome | 2018 |
Geriatric assessment may help decision-making in elderly patients with inoperable, locally advanced non-small-cell lung cancer.
Topics: Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Chemoradiotherapy; Consensus; Decision Making; Female; Geriatric Assessment; Humans; Lung Neoplasms; Male; Palliative Care; Platinum; Prospective Studies; Spain; Survival Analysis; Treatment Outcome | 2018 |
Pharmacogenetics of platinum-based chemotherapy: impact of DNA repair and folate metabolism gene polymorphisms on prognosis of non-small cell lung cancer patients.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; DNA Repair; DNA-Binding Proteins; Endonucleases; Female; Folic Acid; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Pharmacogenetics; Platinum; Prognosis; Proportional Hazards Models; Proto-Oncogene Proteins c-mdm2; Reduced Folate Carrier Protein; Survival Analysis; X-ray Repair Cross Complementing Protein 1; Xeroderma Pigmentosum Group D Protein | 2019 |
Comparing first-line treatment patterns and clinical outcomes of patients with pan-negative advanced non-squamous non-small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Pemetrexed; Platinum; Retrospective Studies; Survival Analysis; Treatment Outcome; Vinorelbine | 2018 |
Topics: Adult; Aged; Alleles; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Copper-Transporting ATPases; Female; Gastrointestinal Tract; Genotype; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Pharmacogenomic Variants; Platinum; Polymorphism, Single Nucleotide; Proportional Hazards Models; Treatment Outcome; Young Adult | 2018 |
Comparative analysis between combination and single-agent chemotherapy for elderly patients with advanced non-small cell lung cancer: A nationwide population-based outcome study.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cohort Studies; Deoxycytidine; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Neoplasm Staging; Platinum; Republic of Korea; Survival Analysis; Treatment Outcome | 2018 |
Immunotherapy in patients who have NSCLC without EGFR or ALK mutations.
Topics: Anaplastic Lymphoma Kinase; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Drug Design; ErbB Receptors; Humans; Lung Neoplasms; Molecular Targeted Therapy; Multicenter Studies as Topic; Pemetrexed; Platinum; Randomized Controlled Trials as Topic; Receptor Protein-Tyrosine Kinases; Treatment Outcome | 2018 |
Genomic profiling in advanced stage non-small-cell lung cancer patients with platinum-based chemotherapy identifies germline variants with prognostic value in SMYD2.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Disease Progression; Female; Genetic Variation; Genome-Wide Association Study; Genotyping Techniques; Germ-Line Mutation; Histone-Lysine N-Methyltransferase; Humans; Lung Neoplasms; Male; Neoplasm Staging; Platinum; Prognosis; Spain | 2018 |
Avelumab in non-small-cell lung cancer.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Carcinoma, Non-Small-Cell Lung; Docetaxel; Humans; Lung Neoplasms; Platinum | 2018 |
Analysis of Relapse Events After Definitive Chemoradiotherapy in Locally Advanced Non-Small-Cell Lung Cancer Patients.
Topics: Carcinoma, Non-Small-Cell Lung; Chemoradiotherapy; Cohort Studies; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Platinum; Retrospective Studies; Survival Analysis; United States | 2019 |
Should chemotherapy plus immune checkpoint inhibition be the standard front-line therapy for patients with metastatic non-small cell lung cancer?
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Humans; Lung Neoplasms; Neoplasm Metastasis; Platinum; Standard of Care; Survival Analysis; Treatment Outcome | 2018 |
Effect of Platinum-Based Chemotherapy on PD-L1 Expression on Tumor Cells in Non-small Cell Lung Cancer.
Topics: Adult; Aged; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Platinum; Prognosis; Retrospective Studies; Survival Analysis; Treatment Outcome; Up-Regulation | 2019 |
Neutrophil-to-lymphocyte ratio is superior to platelet-to-lymphocyte ratio as a prognostic predictor in advanced non-small-cell lung cancer treated with first-line platinum-based chemotherapy.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Blood Platelets; Carcinoma, Non-Small-Cell Lung; Female; Humans; Kaplan-Meier Estimate; Leukocyte Count; Lung Neoplasms; Lymphocytes; Male; Middle Aged; Neoplasm Staging; Neutrophils; Platelet Count; Platinum; Prognosis; ROC Curve; Treatment Outcome | 2019 |
Effect of RIF1 on response of non-small-cell lung cancer patients to platinum-based chemotherapy by regulating MYC signaling pathway.
Topics: Animals; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Histone Deacetylase 1; Histone Deacetylase 2; Histone Deacetylases; Humans; Immunohistochemistry; Lung Neoplasms; Male; Mice; Mice, Nude; Platinum; Repressor Proteins; Signal Transduction; Telomere-Binding Proteins | 2018 |
Does Platinum-Based Chemotherapy Still Have a Role in First-Line Treatment of Advanced Non-Small-Cell Lung Cancer?
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Platinum | 2019 |
Platinum Combination Chemotherapy Is Poorly Tolerated in Malnourished Advanced Lung Cancer Patients with Poor Performance Status.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Male; Malnutrition; Middle Aged; Platinum; Retrospective Studies; Treatment Outcome | 2019 |
Fasting plasma glucose is an independent predictor of survival in patients with locally advanced non-small cell lung cancer treated with concurrent chemoradiotherapy.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Blood Glucose; Carboplatin; Carcinoma, Non-Small-Cell Lung; Chemoradiotherapy; Cohort Studies; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Predictive Value of Tests; Prognosis; Survival Analysis; Treatment Outcome | 2019 |
Real-world treatment patterns among patients with unresected stage III non-small-cell lung cancer.
Topics: Adult; Aged; Anaplastic Lymphoma Kinase; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Disease Progression; Disease-Free Survival; ErbB Receptors; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Staging; Platinum; Proto-Oncogene Proteins p21(ras) | 2019 |
Real-world comparison of immune checkpoint inhibitors in non-small cell lung cancer following platinum-based chemotherapy.
Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Female; Humans; Immunotherapy; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Nivolumab; Platinum; Retrospective Studies | 2020 |
Clinical outcomes to pemetrexed-based versus non-pemetrexed-based platinum doublets in patients with KRAS-mutant advanced non-squamous non-small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Female; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Pemetrexed; Platinum; Progression-Free Survival; Proto-Oncogene Proteins p21(ras); Retrospective Studies; Survival Rate; Young Adult | 2020 |
The predictive value of BRCA1 and RAP80 mRNA expression in advanced non-small-cell lung cancer patients treated with platinum-based chemotherapy.
Topics: BRCA1 Protein; Carcinoma, Non-Small-Cell Lung; Carrier Proteins; Clinical Trials as Topic; Disease-Free Survival; DNA-Binding Proteins; Drug Therapy; Gene Expression Regulation, Neoplastic; Histone Chaperones; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Nuclear Proteins; Platinum; RNA, Messenger | 2013 |
XBP1 promoter polymorphism modulates platinum-based chemotherapy gastrointestinal toxicity for advanced non-small cell lung cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; China; DNA-Binding Proteins; Drug-Related Side Effects and Adverse Reactions; Female; Gastrointestinal Tract; Genotype; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Polymorphism, Genetic; Promoter Regions, Genetic; Regulatory Factor X Transcription Factors; Transcription Factors; X-Box Binding Protein 1 | 2013 |
The impact of both platinum-based chemotherapy and EGFR-TKIs on overall survival of patients with advanced non-small cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase III as Topic; Disease-Free Survival; ErbB Receptors; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Protein Kinase Inhibitors; Randomized Controlled Trials as Topic; Survival Rate | 2014 |
Platinum-based doublet chemotherapy plus bevacizumab without bevacizumab maintenance in advanced non-small cell lung cancer (NSCLC).
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carboplatin; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Female; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Maintenance Chemotherapy; Male; Middle Aged; Neoplasm Staging; Platinum; Vinblastine; Vinorelbine | 2013 |
Formation and repair kinetics of Pt-(GpG) DNA adducts in extracted circulating tumour cells and response to platinum treatment.
Topics: Aged; Carcinoma, Non-Small-Cell Lung; Cisplatin; Dinucleoside Phosphates; DNA Adducts; Humans; Leukocyte Common Antigens; Leukocytes, Mononuclear; Lewis X Antigen; Lung Neoplasms; Middle Aged; Neoplastic Cells, Circulating; Platinum; Tumor Cells, Cultured | 2013 |
Cost effectiveness of first-line pemetrexed plus platinum compared with other regimens in the treatment of patients with nonsquamous non-small cell lung cancer in the US outpatient setting.
Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cost-Benefit Analysis; Disease-Free Survival; Female; Glutamates; Guanine; Humans; Induction Chemotherapy; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Observational Studies as Topic; Pemetrexed; Platinum; Proportional Hazards Models; Retrospective Studies; Treatment Outcome; United States | 2013 |
Predictive value of ERCC1 and RRM1 gene single-nucleotide polymorphisms for first-line platinum- and gemcitabine-based chemotherapy in non-small cell lung cancer patients.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; DNA-Binding Proteins; Endonucleases; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Polymorphism, Single Nucleotide; Prognosis; Ribonucleoside Diphosphate Reductase; Tumor Suppressor Proteins | 2013 |
Excision-repair-cross-complement-1 protein as a prognostic factor in patients with advanced non-small cell lung cancer treated with platinum-based first-line chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Endonucleases; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Prognosis; Retrospective Studies; Risk Factors; Treatment Outcome | 2013 |
[Comparison of platinum-containing doublet chemotherapy and liposome paclitaxel monotherapy for the treatment of elderly patients with advanced non-small cell lung cancer].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Female; Humans; Liposomes; Lung Neoplasms; Male; Paclitaxel; Platinum; Treatment Outcome | 2013 |
Clinical outcome with platinum-based chemotherapy in patients with advanced nonsquamous EGFR wild-type non-small-cell lung cancer segregated according to KRAS mutation status.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anaplastic Lymphoma Kinase; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cohort Studies; ErbB Receptors; Female; Follow-Up Studies; Gene Rearrangement; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Neoplasm Staging; Platinum; Prognosis; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Receptor Protein-Tyrosine Kinases; Survival Rate | 2014 |
Novel association between CD74 polymorphisms and hematologic toxicity in patients with NSCLC after platinum-based chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antigens, Differentiation, B-Lymphocyte; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Adenosquamous; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; DNA, Neoplasm; Female; Follow-Up Studies; Gastrointestinal Diseases; Genotype; Haplotypes; Hematologic Diseases; Histocompatibility Antigens Class II; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Polymorphism, Single Nucleotide; Prognosis | 2014 |
HIF1α genetic variants and protein expressions determine the response to platinum based chemotherapy and clinical outcome in patients with advanced NSCLC.
Topics: Aged; Alleles; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Coordination Complexes; Disease-Free Survival; Female; Genotype; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Polymorphism, Single Nucleotide | 2013 |
Thymidylate synthase polymorphisms are associated to therapeutic outcome of advanced non-small cell lung cancer patients treated with platinum-based chemotherapy.
Topics: Aged; Alleles; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Enhancer Elements, Genetic; Female; Genotype; Humans; Linkage Disequilibrium; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Risk Factors; Thymidylate Synthase | 2014 |
Genetic polymorphisms in XPG could predict clinical outcome of platinum-based chemotherapy for advanced non-small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Endonucleases; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nuclear Proteins; Platinum; Polymorphism, Single Nucleotide; Proportional Hazards Models; Transcription Factors; Treatment Outcome | 2014 |
Effects of polymorphisms in the XRCC1, XRCC3, and XPG genes on clinical outcomes of platinum-based chemotherapy for treatment of non-small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Alleles; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Endonucleases; Female; Follow-Up Studies; Genotype; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Nuclear Proteins; Platinum; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Prognosis; Risk Factors; Transcription Factors; Treatment Outcome; X-ray Repair Cross Complementing Protein 1 | 2014 |
[Efficacies and toxicities of different platinum-based combination chemotherapies for patients with advanced non-small cell lung cancer].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Female; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Retrospective Studies; Treatment Outcome | 2014 |
BMP-4 genetic variants and protein expression are associated with platinum-based chemotherapy response and prognosis in NSCLC.
Topics: Aged; Bone Morphogenetic Protein 4; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Neoplasm Staging; Platinum; Prognosis | 2014 |
Role of XRCC1 and ERCC5 polymorphisms on clinical outcomes in advanced non-small cell lung cancer.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; DNA Repair; DNA-Binding Proteins; Endonucleases; Female; Humans; Male; Middle Aged; Neoplasm Staging; Nuclear Proteins; Platinum; Polymorphism, Single Nucleotide; Transcription Factors; Treatment Outcome; X-ray Repair Cross Complementing Protein 1 | 2014 |
Expression of ERCC1 and BRCA1 predict the clinical outcome of non-small cell lung cancer in patients receiving platinum-based chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; BRCA1 Protein; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Endonucleases; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Neoplasm Staging; Platinum; Prognosis; Proportional Hazards Models | 2014 |
Polymorphisms in ERCC1 gene could predict clinical outcome of platinum-based chemotherapy for non-small cell lung cancer patients.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Endonucleases; Female; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Polymorphism, Genetic; Proportional Hazards Models | 2014 |
Circulating microRNA profiling in patients with advanced non-squamous NSCLC receiving bevacizumab/erlotinib followed by platinum-based chemotherapy at progression (SAKK 19/05).
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Disease Progression; Erlotinib Hydrochloride; Female; Gene Expression; Gene Expression Profiling; Humans; Lung Neoplasms; Male; MicroRNAs; Middle Aged; Neoplasm Staging; Platinum; Prognosis; Prospective Studies; Quinazolines; Reproducibility of Results; Risk Factors | 2014 |
Polymorphisms in TS, MTHFR and ERCC1 genes as predictive markers in first-line platinum and pemetrexed therapy in NSCLC patients.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Endonucleases; Female; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Pemetrexed; Platinum; Polymorphism, Single Nucleotide; Proportional Hazards Models; Retrospective Studies; Thymidylate Synthase | 2014 |
Retrospective evaluation of thromboembolic events in patients with non-small cell lung cancer treated with platinum-based chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Retrospective Studies; Risk Factors; Thromboembolism; Treatment Outcome; Young Adult | 2014 |
Decreased ERCC1 Expression After Platinum-Based Neoadjuvant Chemotherapy in non-Small Cell Lung Cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Biomarkers, Tumor; Biopsy; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Down-Regulation; Endonucleases; Female; Gene Expression Regulation, Neoplastic; Humans; Lung; Lung Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Platinum; Retrospective Studies; Sex Factors; Treatment Outcome | 2015 |
PKM2 as a biomarker for chemosensitivity to front-line platinum-based chemotherapy in patients with metastatic non-small-cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carrier Proteins; Deoxycytidine; Docetaxel; Female; Follow-Up Studies; Gemcitabine; Glutamates; Guanine; Humans; Immunoenzyme Techniques; Lung Neoplasms; Lymphatic Metastasis; Male; Membrane Proteins; Middle Aged; Neoplasm Staging; Pemetrexed; Platinum; Prognosis; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Taxoids; Thyroid Hormone-Binding Proteins; Thyroid Hormones | 2014 |
Heat shock protein 70 as a predictive marker for platinum-based adjuvant chemotherapy in patients with resected non-small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Female; Follow-Up Studies; HSP70 Heat-Shock Proteins; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Prognosis; Retrospective Studies; Treatment Outcome | 2014 |
Expression of the enhancer of zeste homolog 2 in biopsy specimen predicts chemoresistance and survival in advanced non-small cell lung cancer receiving first-line platinum-based chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Carcinoma, Non-Small-Cell Lung; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; Female; Follow-Up Studies; Gene Expression; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Grading; Neoplasm Staging; Platinum; Polycomb Repressive Complex 2; Prognosis; Treatment Outcome | 2014 |
The efficacy and safety of pemetrexed plus bevacizumab in previously treated patients with advanced non-squamous non-small cell lung cancer (ns-NSCLC).
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Bevacizumab; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Pemetrexed; Platinum; Vascular Endothelial Growth Factor A | 2015 |
Clinical effectiveness and clinical toxicity associated with platinum-based doublets in the first-line setting for advanced non-squamous non-small cell lung cancer in Chinese patients: a retrospective cohort study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; China; Cohort Studies; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Odds Ratio; Platinum; Registries; Retrospective Studies; Risk Factors; Treatment Failure; Treatment Outcome | 2014 |
The impact of common and rare EGFR mutations in response to EGFR tyrosine kinase inhibitors and platinum-based chemotherapy in patients with non-small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; DNA Mutational Analysis; ErbB Receptors; Exons; Female; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Neoplasm Grading; Neoplasm Staging; Platinum; Prospective Studies; Protein Kinase Inhibitors; Risk Factors; Treatment Outcome | 2015 |
Prognostic value of ERCC1, ERCC2, XRCC1, and TP53 single nucleotide polymorphisms in patients with early-stage non-small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; DNA-Binding Proteins; Endonucleases; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Platinum; Polymorphism, Single Nucleotide; Prognosis; Tumor Suppressor Protein p53; X-ray Repair Cross Complementing Protein 1; Xeroderma Pigmentosum Group D Protein | 2015 |
ERCC1 SNPs as Potential Predictive Biomarkers in Non-Small Cell Lung Cancer Patients Treated With Platinum-Based Chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Endonucleases; Female; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Polymorphism, Single Nucleotide; RNA, Messenger | 2015 |
Pemetrexed Singlet Versus Nonpemetrexed-Based Platinum Doublet as Second-Line Chemotherapy after First-Line Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor Failure in Non-small Cell Lung Cancer Patients with EGFR Mutations.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; ErbB Receptors; Female; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Pemetrexed; Platinum; Protein Kinase Inhibitors; Retrospective Studies; Treatment Failure | 2015 |
XPG polymorphisms are associated with prognosis of advanced non-small cell lung cancer treated with platinum-based doublet chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Demography; Disease-Free Survival; DNA-Binding Proteins; Endonucleases; Female; Genetic Association Studies; Humans; Lung Neoplasms; Male; Middle Aged; Nuclear Proteins; Platinum; Polymorphism, Single Nucleotide; Prognosis; Transcription Factors | 2015 |
The Efficacy and Safety of Platinum/Vinorelbine as More Than Second-Line Chemotherapy for Advanced Non-small Cell Lung Cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Female; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Retrospective Studies; Vinblastine; Vinorelbine | 2015 |
MMP-9/ANC score as a predictive biomarker for efficacy of bevacizumab plus platinum doublet chemotherapy in patients with advanced or recurrent non-squamous non-small cell lung cancer.
Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Blood Cell Count; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Female; Humans; Male; Matrix Metalloproteinase 9; Middle Aged; Neoplasm Recurrence, Local; Neovascularization, Pathologic; Neutrophils; Paclitaxel; Platinum; Vascular Endothelial Growth Factor A | 2015 |
Cyclooxygenase-2 expression is a prognostic biomarker for non-small cell lung cancer patients treated with adjuvant platinum-based chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cyclooxygenase 2; Female; Follow-Up Studies; Humans; Immunoenzyme Techniques; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Platinum; Prognosis; Retrospective Studies; Survival Rate; Tegafur | 2015 |
[Sequential Treatment of Advanced Squamous Lung Cancer:
First-line Gemcitabine +/- platinum Followed by Second-line Taxanes +/- platinum Versus Reverse Sequence].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Retrospective Studies; Taxoids | 2015 |
Genome-wide Association Study on Platinum-induced Hepatotoxicity in Non-Small Cell Lung Cancer Patients.
Topics: Asian People; Carcinoma, Non-Small-Cell Lung; Chemical and Drug Induced Liver Injury; Demography; Ethnicity; Female; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Polymorphism, Single Nucleotide; Risk Factors | 2015 |
The genotype of ribonucleotidereductase M1 -269C > A is associated with the response to platinum-based chemotherapy and as a prognostic biomarker in advanced nonsmall cell lung cancer.
Topics: Adult; Aged; Alleles; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Disease Progression; Female; Genotype; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Polymorphism, Single Nucleotide; Prognosis; Ribonucleoside Diphosphate Reductase; Risk Factors; Treatment Outcome; Tumor Burden; Tumor Suppressor Proteins | 2015 |
Health-related quality of life after first-line anti-cancer treatments for advanced non-small cell lung cancer in clinical practice.
Topics: Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Erlotinib Hydrochloride; Female; Gefitinib; Gemcitabine; Humans; Lung Neoplasms; Male; Middle Aged; Pemetrexed; Platinum; Prospective Studies; Quality of Life; Quinazolines; Sickness Impact Profile; Surveys and Questionnaires; World Health Organization | 2016 |
Lymphocyte to monocyte ratio is associated with response to first-line platinum-based chemotherapy and prognosis of early-stage non-small cell lung cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Female; Humans; Kaplan-Meier Estimate; Lymphocyte Count; Lymphocytes; Male; Middle Aged; Monocytes; Neoplasm Staging; Nomograms; Platinum; Prognosis; Proportional Hazards Models | 2016 |
Comparison of Single Agent Gemcitabine and Docetaxel in Second-Line Therapy for Advanced Stage Non-Small Cell Lung Cancer in a University Hospital in Turkey.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Disease Progression; Docetaxel; Female; Gemcitabine; Hospitals, University; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Retrospective Studies; Taxoids; Turkey | 2015 |
Polymorphisms of BCL2 and BAX Genes Associate with Outcomes in Advanced Non-small cell lung cancer Patients treated with platinum-based Chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Alleles; Antineoplastic Combined Chemotherapy Protocols; bcl-2-Associated X Protein; Carcinoma, Non-Small-Cell Lung; Female; Genotype; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Polymorphism, Single Nucleotide; Prognosis; Proto-Oncogene Proteins c-bcl-2 | 2015 |
Poor response to platinum-based chemotherapy is associated with KRAS mutation and concomitant low expression of BRAC1 and TYMS in NSCLC.
Topics: Adult; Aged; Aged, 80 and over; BRCA1 Protein; Carcinoma, Non-Small-Cell Lung; Demography; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Platinum; Proto-Oncogene Proteins p21(ras); RNA, Messenger; Thymidylate Synthase; Treatment Outcome | 2016 |
Non-small cell lung cancer patients with brain metastases treated with first-line platinum-doublet chemotherapy: Analysis from the European FRAME study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Europe; Female; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Platinum; Retreatment; Treatment Outcome | 2015 |
[Effect of polymorphisms of NF-κB and PXR on platinum-based chemotherapy for non-small cell lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Genotype; Humans; Lung Neoplasms; NF-kappa B; Platinum; Polymorphism, Genetic; Pregnane X Receptor; Receptors, Steroid; Transcription Factor RelA | 2016 |
Reactive Oxygen Species Modulator 1 (Romo1) Predicts Poor Outcomes in Advanced Non-small Cell Lung Cancer Patients Treated with Platinum-Based Chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Female; Gene Expression; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Lung Neoplasms; Male; Membrane Proteins; Middle Aged; Mitochondrial Proteins; Neoplasm Grading; Neoplasm Staging; Platinum; Prognosis; Treatment Outcome | 2017 |
[Evaluation of the Efficacy and Safety of Platinum Doublet Re-Challenge Chemotherapy in Patients with Recurrent Advanced Non-Small Cell Lung Cancer].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Recurrence; Retrospective Studies | 2016 |
Serum APE1 as a predictive marker for platinum-based chemotherapy of non-small cell lung cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; DNA-(Apurinic or Apyrimidinic Site) Lyase; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Prognosis; Proportional Hazards Models; ROC Curve; Treatment Outcome | 2016 |
ERCC1 as Predictor of Platinum Benefit in Non-Small-Cell Lung Cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Endonucleases; Humans; Lung Neoplasms; Platinum; Prospective Studies | 2017 |
The 5'UTR variant of ERCC5 fails to influence outcomes in ovarian and lung cancer patients undergoing treatment with platinum-based drugs.
Topics: 5' Untranslated Regions; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Ovarian Epithelial; DNA-Binding Proteins; Endonucleases; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasms, Glandular and Epithelial; Nuclear Proteins; Ovarian Neoplasms; Pharmacogenomic Variants; Platinum; Polymorphism, Genetic; Survival Analysis; Transcription Factors; Treatment Outcome | 2016 |
Vitamin D deficiency is associated with a poor prognosis in advanced non-small cell lung cancer patients treated with platinum-based first-line chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Prognosis; Survival Analysis; Vitamin D; Vitamin D Deficiency | 2017 |
Lung cancer: ET - platinum therapy comes home.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Humans; Lung Neoplasms; Platinum | 2017 |
The Challenges of Validating in Precision Medicine: The Case of Excision Repair Cross-Complement Group 1 Diagnostic Testing.
Topics: Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; DNA Repair; DNA-Binding Proteins; Endonucleases; Humans; Platinum; Precision Medicine | 2017 |
Effect of BRCA1 haplotype on survival of non-small-cell lung cancer patients treated with platinum-based chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Female; Gene Frequency; Genotype; Haplotypes; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Polymorphism, Genetic; Prognosis; Ubiquitin-Protein Ligases | 2008 |
Expression of excision repair cross-complementation group 1 protein predicts poor outcome in advanced non-small cell lung cancer patients treated with platinum-based doublet chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; bcl-2-Associated X Protein; Carcinoma, Non-Small-Cell Lung; Cisplatin; Deoxycytidine; Disease Progression; DNA-Binding Proteins; Drug Resistance, Neoplasm; Endonucleases; Female; Gemcitabine; Humans; Immunohistochemistry; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Pleural Effusion, Malignant; Prognosis; Proto-Oncogene Proteins c-bcl-2; Recurrence; Survival Analysis; Treatment Outcome; Tumor Suppressor Protein p53 | 2009 |
Patient attitudes towards chemotherapy and survival: a prospective observational study in advanced non-small cell lung cancer.
Topics: Aged; Antineoplastic Agents; Attitude to Health; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Drug Therapy; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Observation; Platinum; Prospective Studies | 2009 |
Impact of angiotensin I converting enzyme inhibitors and angiotensin II type 1 receptor blockers on survival in patients with advanced non-small-cell lung cancer undergoing first-line platinum-based chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Carcinoma, Adenosquamous; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Female; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Prognosis; Retrospective Studies; Survival Rate | 2009 |
[Prognostic significance of ERCC1 mRNA expression in patients with non-small cell lung cancer receiving platinum-based chemotherapy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cisplatin; Disease-Free Survival; DNA-Binding Proteins; Endonucleases; Female; Follow-Up Studies; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Paraffin Embedding; Platinum; Proportional Hazards Models; RNA, Messenger; Survival Rate | 2009 |
[Comparison of single-agent docetaxel versus docetaxel plus platinum combination agent in second-line treatment for advanced non-small cell lung cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Docetaxel; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Retrospective Studies; Taxoids; Treatment Outcome | 2009 |
Pemetrexed monotherapy versus pemetrexed plus platinum combination as second-line treatment for advanced non-small cell lung cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Female; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Middle Aged; Pemetrexed; Platinum; Retrospective Studies; Treatment Outcome | 2009 |
Smoking intensity, oxidative stress and chemotherapy in nonsmall cell lung cancer: a correlated prognostic study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Female; Humans; Lung Neoplasms; Male; Middle Aged; Oxidative Stress; Platinum; Prognosis; Smoking | 2009 |
[Comparison between single-agent and platinum-doublet chemotherapy in elderly patients with non-small cell lung cancer].
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Female; Humans; Lung Neoplasms; Male; Platinum; Retrospective Studies; Survival Rate | 2010 |
Stability of markers used for real-time tumor tracking after percutaneous intrapulmonary placement.
Topics: Carcinoma, Non-Small-Cell Lung; Exhalation; Female; Fiducial Markers; Foreign-Body Migration; Humans; Linear Models; Lung Neoplasms; Male; Platinum; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Tomography, X-Ray Computed; Tumor Burden | 2011 |
Tubulin, BRCA1, ERCC1, Abraxas, RAP80 mRNA expression, p53/p21 immunohistochemistry and clinical outcome in patients with advanced non small-cell lung cancer receiving first-line platinum-gemcitabine chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Pharmacological; BRCA1 Protein; Carcinoma, Non-Small-Cell Lung; Carrier Proteins; Cyclin-Dependent Kinase Inhibitor p21; Deoxycytidine; Disease Progression; DNA-Binding Proteins; Endonucleases; Female; Gemcitabine; Histone Chaperones; Humans; Immunohistochemistry; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Nuclear Proteins; Platinum; Predictive Value of Tests; RNA, Messenger; Treatment Outcome; Tubulin; Tumor Suppressor Protein p53 | 2011 |
Genetic variations in multiple drug action pathways and survival in advanced stage non-small cell lung cancer treated with chemotherapy.
Topics: Antineoplastic Agents; Bridged-Ring Compounds; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Deoxycytidine; DNA Repair; ErbB Receptors; Female; Gemcitabine; Glutathione; Glutathione Peroxidase; Humans; Lung Neoplasms; Male; Platinum; Polymorphism, Single Nucleotide; Prognosis; Proto-Oncogene Proteins c-raf; Taxoids | 2011 |
Role of DNA repair gene polymorphisms in the efficiency of platinum-based adjuvant chemotherapy for non-small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; DNA-Binding Proteins; Endonucleases; Female; Genotype; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Male; Middle Aged; Platinum; Polymorphism, Genetic | 2011 |
[Efficacy and safety of gefitinib or docetaxel in Chinese patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) who had failed previous platinum-based first-line chemotherapy].
Topics: Adult; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Diarrhea; Disease-Free Survival; Docetaxel; Exanthema; Female; Gefitinib; Humans; Lung Neoplasms; Male; Neoplasm Staging; Neutropenia; Platinum; Quality of Life; Quinazolines; Randomized Controlled Trials as Topic; Remission Induction; Retrospective Studies; Survival Rate; Taxoids | 2011 |
Genetic polymorphisms of GSTP1 and XRCC1: prediction of clinical outcome of platinum-based chemotherapy in advanced non-small cell lung cancer (NSCLC) patients.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; DNA Repair; DNA-Binding Proteins; Female; Gene Frequency; Genotype; Glutathione S-Transferase pi; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Platinum; Polymorphism, Single Nucleotide; Prognosis; X-ray Repair Cross Complementing Protein 1 | 2011 |
[Nimotuzumab in combination with chemotherapy in patients with advanced non-small cell lung cancer].
Topics: Adult; Aged; Agranulocytosis; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Exanthema; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Remission Induction; Retrospective Studies; Thrombocytopenia; Vomiting | 2011 |
[Relationship of insulin-like growth factor receptor single nucleotide polymorphism (SNP) with platinum-based chemotherapy outcomes in advanced non-small cell lung cancer].
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Female; Humans; Male; Middle Aged; Platinum; Polymorphism, Single Nucleotide; Receptor, IGF Type 1; Receptor, IGF Type 2; Receptors, Somatomedin; Treatment Outcome | 2012 |
The qualification of docetaxel or erlotinib for second-line therapy should be based on clinical and molecular predictive factors.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Docetaxel; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Mutation; Platinum; Predictive Value of Tests; Proportional Hazards Models; Quinazolines; Smoking; Taxoids; Tubulin | 2012 |
Association of CASP7 polymorphisms and survival of patients with non-small cell lung cancer with platinum-based chemotherapy treatment.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Caspase 7; Drug Therapy; Female; Genotype; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Pharmacogenetics; Platinum; Polymorphism, Single Nucleotide; Prognosis; Regression Analysis; Retrospective Studies; Survival Rate; Treatment Outcome | 2012 |
[Effect of pemetrexed plus platinum for chemotherapy-naive advanced non-small cell lung cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Female; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Middle Aged; Pemetrexed; Platinum; Retrospective Studies; Thymidylate Synthase; Treatment Outcome; Young Adult | 2012 |
Galectin-3 genetic variants are associated with platinum-based chemotherapy response and prognosis in patients with NSCLC.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Female; Galectin 3; Genetic Predisposition to Disease; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Polymorphism, Single Nucleotide; Prognosis; Proportional Hazards Models; Survival Analysis | 2012 |
Genetic polymorphism of XRCC1 Arg399Gln is associated with survival in non-small-cell lung cancer patients treated with gemcitabine/platinum.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; DNA-Binding Proteins; DNA, Neoplasm; Drug Therapy, Combination; Female; Follow-Up Studies; Gemcitabine; Genotype; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Polymerase Chain Reaction; Polymorphism, Genetic; Retrospective Studies; Ribonucleotide Reductases; Survival Rate; Taiwan; Treatment Outcome; X-ray Repair Cross Complementing Protein 1 | 2012 |
ERCC1 expression in circulating tumor cells (CTCs) using a novel detection platform correlates with progression-free survival (PFS) in patients with metastatic non-small-cell lung cancer (NSCLC) receiving platinum chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Endonucleases; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplastic Cells, Circulating; Platinum | 2012 |
Association between CASP8 and CASP10 polymorphisms and toxicity outcomes with platinum-based chemotherapy in Chinese patients with non-small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Asian People; Carcinoma, Non-Small-Cell Lung; Caspase 10; Caspase 8; Cisplatin; Female; Gene Frequency; Haplotypes; Humans; Logistic Models; Lung Neoplasms; Male; Middle Aged; Platinum; Polymorphism, Single Nucleotide | 2012 |
Tissue platinum concentration and tumor response in non-small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Agents; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cisplatin; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Humans; Lung Neoplasms; Male; Middle Aged; Multivariate Analysis; Neoadjuvant Therapy; Platinum; Survival Analysis | 2012 |
Structure-cytotoxicity relationship for different types of mononuclear platinum(II) complexes with 5,7-ditertbutyl-1,2,4-triazolo[1,5-a]pyrimidine.
Topics: Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cytotoxins; Female; Humans; Lung Neoplasms; Platinum; Pyrimidines; Structure-Activity Relationship; X-Ray Diffraction | 2012 |
Advanced non-small cell lung cancer (NSCLC): maintenance therapy for all?
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Erlotinib Hydrochloride; Glutamates; Guanine; Humans; Induction Chemotherapy; Lung Neoplasms; Neoplasm Staging; Pemetrexed; Platinum; Quinazolines | 2012 |
Outcomes after adjuvant platinum-based chemotherapy in elderly NSCLC patients with T4 disease.
Topics: Adenocarcinoma; Aged; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Neoplasm Recurrence, Local; Neoplasm Staging; Platinum; Prognosis; SEER Program; Survival Rate | 2013 |
Association between single nucleotide polymorphisms (SNPs) and toxicity of advanced non-small-cell lung cancer patients treated with chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; DNA Repair; Female; Genotype; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Polymorphism, Single Nucleotide; Retrospective Studies | 2012 |
Timing of chemotherapy-induced neutropenia is a prognostic factor in patients with metastatic non-small-cell lung cancer: a retrospective analysis in gemcitabine-plus-platinum-treated patients.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neutropenia; Platinum; Prognosis; Retrospective Studies; Survival Analysis; Time Factors; Treatment Outcome | 2013 |
Paclitaxel plus platinum or gemcitabine plus platinum in first-line treatment of advanced non-small-cell lung cancer: results from 6 randomized controlled trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Drug-Related Side Effects and Adverse Reactions; Gemcitabine; Humans; Neoplasm Staging; Paclitaxel; Platinum; Randomized Controlled Trials as Topic; Treatment Outcome | 2013 |
Computed tomography RECIST assessment of histopathologic response and prediction of survival in patients with resectable non-small-cell lung cancer after neoadjuvant chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Platinum; Prognosis; Retrospective Studies; Survival Rate; Taxoids; Tomography, X-Ray Computed | 2013 |
Inter- and intratumoral disposition of platinum in solid tumors after administration of cisplatin.
Topics: Animals; Antineoplastic Agents; Area Under Curve; Carcinoma, Non-Small-Cell Lung; Cisplatin; DNA Adducts; DNA, Neoplasm; Factor VIII; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, SCID; Microdialysis; Models, Biological; Neoplasm Proteins; Neovascularization, Pathologic; Platinum; Specific Pathogen-Free Organisms; Tissue Distribution; Xenograft Model Antitumor Assays | 2002 |
A retrospective analysis of the outcome of patients who have received two prior chemotherapy regimens including platinum and docetaxel for recurrent non-small-cell lung cancer.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Disease Progression; Docetaxel; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Paclitaxel; Platinum; Retrospective Studies; Survival Rate; Taxoids; Time Factors; Treatment Outcome | 2003 |
Activity of weekly irinotecan (CPT-11) in patients with advanced non-small cell lung cancer pretreated with platinum and taxanes.
Topics: Adult; Aged; Camptothecin; Carcinoma, Non-Small-Cell Lung; Confidence Intervals; Drug Administration Schedule; Female; Hematologic Diseases; Humans; Irinotecan; Karnofsky Performance Status; Lung Neoplasms; Male; Middle Aged; Platinum; Prospective Studies; Taxoids | 2003 |
Excision repair cross-complementation group 1 polymorphism predicts overall survival in advanced non-small cell lung cancer patients treated with platinum-based chemotherapy.
Topics: Adult; Aged; Alleles; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Codon; DNA Repair; DNA-Binding Proteins; Drug Resistance, Neoplasm; Endonucleases; Female; Genotype; Humans; Linkage Disequilibrium; Lung Neoplasms; Male; Middle Aged; Platinum; Polymorphism, Genetic; RNA, Messenger; Time Factors; Treatment Outcome | 2004 |
Paclitaxel/Platinum-based perioperative chemotherapy and surgery in stage IIIA non-small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Disease Progression; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Paclitaxel; Perioperative Care; Platinum; Pneumonectomy; Survival Rate; Treatment Outcome | 2005 |
[Polymorphisms in nucleotide excision repair genes XPC and XPD and clinical responses to platinum-based chemotherapy in advanced non-small cell lung cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; DNA Repair; DNA-Binding Proteins; Female; Genotype; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Polymorphism, Genetic; Prospective Studies; Xeroderma Pigmentosum Group D Protein | 2005 |
A slow disengagement from platinum-based chemotherapy for patients with advanced non-small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Non-Small-Cell Lung; Diarrhea; Drug Administration Schedule; Humans; Irinotecan; Lung Neoplasms; Maximum Tolerated Dose; Neutropenia; Paclitaxel; Platinum; Survival Rate; Time Factors | 2005 |
Common arm analysis: one approach to develop the basis for global standardization in clinical trials of non-small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Carcinoma, Non-Small-Cell Lung; Cisplatin; Clinical Trials, Phase III as Topic; Deoxycytidine; Europe; Gemcitabine; Humans; Japan; Lung Neoplasms; Platinum; Retrospective Studies; Survival Rate; Taxoids; United States; Vinblastine; Vinorelbine | 2006 |
Role of platinum-based radio-chemotherapy for locally advanced non-small-cell lung cancer: possible influence of type of platinum on survival data.
Topics: Antineoplastic Agents; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cisplatin; Combined Modality Therapy; Humans; Lung Neoplasms; Meta-Analysis as Topic; Neoplasm Staging; Platinum; Survival Analysis | 2006 |
Is trimodality approach better then bimodality in stage IIIA, N2 positive non-small cell lung cancer?
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Combined Modality Therapy; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Paclitaxel; Platinum; Radiotherapy; Treatment Outcome | 2006 |
Quality of life assessment in the TAX 326 study.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carcinoma, Non-Small-Cell Lung; Cisplatin; Docetaxel; Female; Humans; Lung Neoplasms; Male; Middle Aged; Pain; Patient Compliance; Platinum; Psychomotor Performance; Quality of Life; Sickness Impact Profile; Taxoids; Treatment Outcome; Vinblastine; Vinorelbine | 2007 |
Treatment of non-small cell lung cancer, stage IIIB: ACCP evidence-based clinical practice guidelines (2nd edition).
Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cytotoxins; Evidence-Based Medicine; Humans; Lung Neoplasms; Neoplasm Staging; Paclitaxel; Platinum; Quality of Life; Treatment Outcome | 2007 |
The cigarette burden (measured by the number of pack-years smoked) negatively impacts the response rate to platinum-based chemotherapy in lung cancer patients.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brazil; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Platinum; Prognosis; Retrospective Studies; Risk Factors; Smoking; Treatment Outcome | 2008 |
Brief report: retrospective review of efficacy of erlotinib or gefitinib compared to docetaxel as subsequent line therapy in advanced non-small cell lung cancer (NSCLC) following failure of platinum-based chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Disease Progression; Docetaxel; ErbB Receptors; Female; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Protein-Tyrosine Kinases; Retrospective Studies; Survival Analysis; Taxoids; Treatment Outcome | 2008 |
Concurrent daily carboplatin and accelerated hyperfractionated thoracic radiotherapy in locally advanced nonsmall cell lung cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Carboplatin; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Drug Administration Schedule; Esophagitis; Feasibility Studies; Female; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Radiotherapy Dosage; Survival Analysis | 1997 |
Intraoperative intrapleural hypotonic cisplatin treatment for carcinomatous pleuritis.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cisplatin; Female; Humans; Hypotonic Solutions; Intraoperative Care; Lung Neoplasms; Male; Middle Aged; Platinum; Pleural Effusion, Malignant; Pleurisy; Retrospective Studies; Survival Rate; Thoracotomy | 1997 |
Mechanisms of synergism between cisplatin and gemcitabine in ovarian and non-small-cell lung cancer cell lines.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Lewis Lung; Carcinoma, Non-Small-Cell Lung; Cell Division; Cisplatin; Deoxycytidine; DNA; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Drug Synergism; Female; Fluorometry; Gemcitabine; Humans; Intracellular Fluid; Lung Neoplasms; Mice; Ovarian Neoplasms; Platinum; RNA; Time Factors; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1999 |
Tolerability of the cytoprotective agent amifostine in elderly patients receiving chemotherapy: a comparative study.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Amifostine; Antihypertensive Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cyclophosphamide; Deoxycytidine; Doxorubicin; Epirubicin; Esophageal Neoplasms; Female; Fluorouracil; Gemcitabine; Humans; Hypertension; Hypocalcemia; Hypotension; Infusions, Intravenous; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Middle Aged; Nausea; Paclitaxel; Pancreatic Neoplasms; Platinum; Prednisone; Premedication; Retrospective Studies; Vincristine | 2001 |
Anticancer activity in murine and human tumor cell lines of bis(platinum) complexes incorporating straight-chain aliphatic diamine linker groups.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cisplatin; Colonic Neoplasms; Diamines; Drug Resistance; Humans; Leukemia L1210; Leukemia, Experimental; Lung Neoplasms; Malonates; Mammary Neoplasms, Experimental; Melanoma, Experimental; Mice; Mice, Nude; Molecular Structure; Platinum; Structure-Activity Relationship; Tumor Cells, Cultured | 1992 |
Prediction of the antitumor activity of new platinum analogs based on their ex vivo pharmacodynamics as determined by bioassay.
Topics: Antineoplastic Agents; Biological Assay; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Humans; Lung Neoplasms; Organoplatinum Compounds; Platinum; Tumor Cells, Cultured | 1991 |
Tumor-tissue and plasma concentrations of platinum during chemotherapy of non-small-cell lung cancer patients.
Topics: Adult; Aged; Biopsy; Bronchoscopy; Carcinoma, Non-Small-Cell Lung; Cisplatin; Diffusion; Drug Administration Schedule; Female; Fiber Optic Technology; Humans; Lung Neoplasms; Male; Middle Aged; Platinum; Prospective Studies; Spectrophotometry, Atomic | 1990 |
[Clinical studies of bronchial arterial infusion of CDDP for the treatment of lung cancer--research on the platinum concentration in the tumor and pulmonary parenchyma].
Topics: Aged; Bronchial Arteries; Carcinoma, Non-Small-Cell Lung; Cisplatin; Female; Humans; Infusions, Intra-Arterial; Lung; Lung Neoplasms; Male; Middle Aged; Platinum | 1989 |
High-dose cisplatin in hypertonic saline: reduced toxicity of a modified dose schedule and correlation with plasma pharmacokinetics. A Northern California Oncology Group Pilot Study in non-small-cell lung cancer.
Topics: Adult; Aged; California; Carcinoma, Non-Small-Cell Lung; Cisplatin; Drug Administration Schedule; Female; Humans; Kinetics; Lung Neoplasms; Male; Middle Aged; Peripheral Nervous System Diseases; Pilot Projects; Platinum; Saline Solution, Hypertonic | 1986 |