pk 11195 has been researched along with Stress Disorders, Post-Traumatic in 4 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
Stress Disorders, Post-Traumatic: A class of traumatic stress disorders with symptoms that last more than one month.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In combat-related PTSD, the 18 kDa mitochondrial translocator protein (TSPO), essential for steroid synthesis, was found to be decreased." | 1.36 | Lifetime manic-hypomanic symptoms in post-traumatic stress disorder: relationship with the 18 kDa mitochondrial translocator protein density. ( Carmassi, C; Ciapparelli, A; Da Pozzo, E; Dell'Osso, L; Martini, C; Trincavelli, ML, 2010) |
| "[3H]PK 11195 was used to label platelet PBR." | 1.29 | Altered platelet peripheral-type benzodiazepine receptor in posttraumatic stress disorder. ( Bidder, M; Fisher, D; Fonia, O; Gavish, M; Karp, L; Laor, N; Muller, U; Reiss, A; Weizman, R; Wolmer, L, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, LM | 2 |
| Qiu, ZK | 2 |
| Zhao, N | 2 |
| Chen, HX | 2 |
| Liu, YQ | 1 |
| Xu, JP | 1 |
| Zhang, YZ | 2 |
| Yang, RF | 2 |
| Li, YF | 2 |
| Chen, XF | 1 |
| Xue, R | 1 |
| Dell'Osso, L | 1 |
| Da Pozzo, E | 1 |
| Carmassi, C | 1 |
| Trincavelli, ML | 1 |
| Ciapparelli, A | 1 |
| Martini, C | 1 |
| Gavish, M | 1 |
| Laor, N | 1 |
| Bidder, M | 1 |
| Fisher, D | 1 |
| Fonia, O | 1 |
| Muller, U | 1 |
| Reiss, A | 1 |
| Wolmer, L | 1 |
| Karp, L | 1 |
| Weizman, R | 1 |
4 other studies available for pk 11195 and Stress Disorders, Post-Traumatic
| Article | Year |
|---|---|
Anxiolytic-like effects of YL-IPA08, a potent ligand for the translocator protein (18 kDa) in animal models of post-traumatic stress disorder.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Disease Models, Animal; Dose-Response Relationsh | 2014 |
Involvement of allopregnanolone in the anti-PTSD-like effects of AC-5216.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Disease Models, Animal; Fear; Hippocampus; Isoquinolines; Mal | 2016 |
Lifetime manic-hypomanic symptoms in post-traumatic stress disorder: relationship with the 18 kDa mitochondrial translocator protein density.
Topics: Adult; Antineoplastic Agents; Bipolar Disorder; Female; Humans; Isoquinolines; Life Change Events; L | 2010 |
Altered platelet peripheral-type benzodiazepine receptor in posttraumatic stress disorder.
Topics: Adult; Aged; Binding, Competitive; Down-Regulation; Female; Humans; Isoquinolines; Male; Middle Aged | 1996 |