pk 11195 has been researched along with Sciatica in 1 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
Sciatica: A condition characterized by pain radiating from the back into the buttock and posterior/lateral aspects of the leg. Sciatica may be a manifestation of SCIATIC NEUROPATHY; RADICULOPATHY (involving the SPINAL NERVE ROOTS; L4, L5, S1, or S2, often associated with INTERVERTEBRAL DISK DISPLACEMENT); or lesions of the CAUDA EQUINA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "0 mm) alleviated the mechanical allodynia in neuropathic pain, while the TSPO inhibitor PK 11195 exacerbated it." | 3.83 | Elevated Neurosteroids in the Lateral Thalamus Relieve Neuropathic Pain in Rats with Spared Nerve Injury. ( Hou, Y; Li, YF; Liu, FY; Liu, J; Wan, Y; Wu, H; Yi, M; Yin, Y; Zhang, M; Zheng, L; Zhou, MM, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, M | 1 |
| Liu, J | 1 |
| Zhou, MM | 1 |
| Wu, H | 1 |
| Hou, Y | 1 |
| Li, YF | 1 |
| Yin, Y | 1 |
| Zheng, L | 1 |
| Liu, FY | 1 |
| Yi, M | 1 |
| Wan, Y | 1 |
1 other study available for pk 11195 and Sciatica
| Article | Year |
|---|---|
Elevated Neurosteroids in the Lateral Thalamus Relieve Neuropathic Pain in Rats with Spared Nerve Injury.
Topics: Animals; Antineoplastic Agents; Bicuculline; Calcium-Binding Proteins; Carrier Proteins; Disease Mod | 2016 |