pk 11195 has been researched along with Parkinsonian Disorders in 4 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
Parkinsonian Disorders: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cumming, P | 2 |
| Pedersen, MD | 1 |
| Minuzzi, L | 1 |
| Mezzomo, K | 1 |
| Danielsen, EH | 2 |
| Iversen, P | 1 |
| Aagaard, D | 1 |
| Keiding, S | 1 |
| Munk, OL | 1 |
| Finsen, B | 1 |
| Bartels, AL | 1 |
| Leenders, KL | 1 |
| Chen, MK | 1 |
| Kuwabara, H | 1 |
| Zhou, Y | 1 |
| Adams, RJ | 1 |
| Brasić, JR | 1 |
| McGlothan, JL | 1 |
| Verina, T | 1 |
| Burton, NC | 1 |
| Alexander, M | 1 |
| Kumar, A | 1 |
| Wong, DF | 1 |
| Guilarte, TR | 1 |
| Vafaee, M | 1 |
| Falborg, L | 1 |
| Steffensen, E | 1 |
| Sørensen, JC | 1 |
| Gillings, N | 1 |
| Bender, D | 1 |
| Marthi, K | 1 |
| Andersen, F | 1 |
| Munk, O | 1 |
| Smith, D | 1 |
| Møller, A | 1 |
| Gjedde, A | 1 |
1 review available for pk 11195 and Parkinsonian Disorders
| Article | Year |
|---|---|
Neuroinflammation in the pathophysiology of Parkinson's disease: evidence from animal models to human in vivo studies with [11C]-PK11195 PET.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cyclooxygenase 2; Cytokines; Disease Models | 2007 |
3 other studies available for pk 11195 and Parkinsonian Disorders
| Article | Year |
|---|---|
Distribution of PK11195 binding sites in porcine brain studied by autoradiography in vitro and by positron emission tomography.
Topics: Animals; Autoradiography; Binding Sites; Brain; Carbon Radioisotopes; Female; In Vitro Techniques; I | 2006 |
VMAT2 and dopamine neuron loss in a primate model of Parkinson's disease.
Topics: Animals; Autoradiography; Brain; Carbon Isotopes; Carrier Proteins; Cocaine; Disease Models, Animal; | 2008 |
Normalization of markers for dopamine innervation in striatum of MPTP-lesioned miniature pigs with intrastriatal grafts.
Topics: Animals; Antineoplastic Agents; Dihydroxyphenylalanine; Dopamine; Graft Survival; Isoquinolines; Par | 2001 |