pk 11195 has been researched along with Obsessive-Compulsive Disorder in 5 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
Obsessive-Compulsive Disorder: An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of the present study was to investigate whether platelet MBR are altered in untreated obsessive-compulsive disorder (OCD) patients and whether chronic treatment with clomipramine (CMI) regulates these receptors." | 3.68 | The platelet benzodiazepine receptor is unaltered in obsessive-compulsive disorder. ( Dar, DE; Gavish, M; Hermesh, H; Karp, L; Munitz, H; Weizman, R, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kumar, A | 1 |
| Williams, MT | 1 |
| Chugani, HT | 1 |
| Marazziti, D | 1 |
| Rotondo, A | 1 |
| Martini, C | 1 |
| Giannaccini, G | 1 |
| Lucacchini, A | 1 |
| Pancioli-Guadagnucci, ML | 1 |
| Diamond, BI | 1 |
| Borison, R | 1 |
| Cassano, GB | 1 |
| Weizman, R | 1 |
| Hermesh, H | 1 |
| Karp, L | 1 |
| Dar, DE | 1 |
| Munitz, H | 1 |
| Gavish, M | 1 |
| Rocca, P | 2 |
| Beoni, AM | 1 |
| Eva, C | 1 |
| Ferrero, P | 2 |
| Maina, G | 2 |
| Bogetto, F | 1 |
| Ravizza, L | 2 |
| Gualerzi, A | 1 |
| Zanalda, E | 1 |
| Bergamasco, B | 1 |
5 other studies available for pk 11195 and Obsessive-Compulsive Disorder
| Article | Year |
|---|---|
Evaluation of basal ganglia and thalamic inflammation in children with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection and tourette syndrome: a positron emission tomographic (PET) study using 11C-[R]-PK11195.
Topics: Adolescent; Adult; Aging; Autoimmune Diseases; Basal Ganglia; Carbon Radioisotopes; Child; Humans; I | 2015 |
Changes in peripheral benzodiazepine receptors in patients with panic disorder and obsessive-compulsive disorder.
Topics: Adolescent; Adult; Biomarkers; Blood Platelets; Cell Membrane; Female; Humans; In Vitro Techniques; | 1994 |
The platelet benzodiazepine receptor is unaltered in obsessive-compulsive disorder.
Topics: Adult; Blood Platelets; Clomipramine; Female; Humans; Isoquinolines; Male; Middle Aged; Mitochondria | 1993 |
Lymphocyte peripheral benzodiazepine receptor mRNA decreases in obsessive-compulsive disorder.
Topics: Adult; Analysis of Variance; Female; Humans; Isoquinolines; Lymphocytes; Male; Obsessive-Compulsive | 2000 |
Peripheral-type benzodiazepine receptors in anxiety disorders.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Humans; Isoquinolines; Long-Term Care; Lymphocytes; N-Methyl | 1991 |