pk 11195 has been researched along with Necrosis in 2 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The possibility that sleep deprivation may result in functional deficits, or that structural changes may emerge after repeated episodes of sleep deprivation, remains to be addressed." | 1.31 | Sleep deprivation does not affect indices of necrosis or apoptosis in rat brain. ( D'Almeida, V; Hipólide, DC; Nobrega, JN; Raymond, R; Tufik, S, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hipólide, DC | 1 |
| D'Almeida, V | 1 |
| Raymond, R | 1 |
| Tufik, S | 1 |
| Nobrega, JN | 1 |
| Muscarella, DE | 1 |
| O'Brien, KA | 1 |
| Lemley, AT | 1 |
| Bloom, SE | 1 |
2 other studies available for pk 11195 and Necrosis
| Article | Year |
|---|---|
Sleep deprivation does not affect indices of necrosis or apoptosis in rat brain.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Brain; Genes, bcl-2; Hypothalamus; In Situ Nick-End | 2002 |
Reversal of Bcl-2-mediated resistance of the EW36 human B-cell lymphoma cell line to arsenite- and pesticide-induced apoptosis by PK11195, a ligand of the mitochondrial benzodiazepine receptor.
Topics: Antineoplastic Agents; Apoptosis; Arsenites; Benzimidazoles; Cell Line, Tumor; Drug Resistance, Neop | 2003 |