pk 11195 has been researched along with Multiple System Atrophy Syndrome in 2 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dodel, R | 1 |
| Spottke, A | 1 |
| Gerhard, A | 2 |
| Reuss, A | 1 |
| Reinecker, S | 1 |
| Schimke, N | 1 |
| Trenkwalder, C | 1 |
| Sixel-Döring, F | 1 |
| Herting, B | 1 |
| Kamm, C | 1 |
| Gasser, T | 1 |
| Sawires, M | 1 |
| Geser, F | 1 |
| Köllensperger, M | 1 |
| Seppi, K | 1 |
| Kloss, M | 1 |
| Krause, M | 1 |
| Daniels, C | 1 |
| Deuschl, G | 1 |
| Böttger, S | 1 |
| Naumann, M | 1 |
| Lipp, A | 1 |
| Gruber, D | 1 |
| Kupsch, A | 1 |
| Du, Y | 1 |
| Turkheimer, F | 2 |
| Brooks, DJ | 2 |
| Klockgether, T | 1 |
| Poewe, W | 1 |
| Wenning, G | 1 |
| Schade-Brittinger, C | 1 |
| Oertel, WH | 1 |
| Eggert, K | 1 |
| Banati, RB | 1 |
| Goerres, GB | 1 |
| Cagnin, A | 1 |
| Myers, R | 1 |
| Gunn, RN | 1 |
| Good, CD | 1 |
| Mathias, CJ | 1 |
| Quinn, N | 1 |
| Schwarz, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Double-blind, Randomised, Placebo-controlled Parallel Group Study to Investigate the Effect of EGCG Supplementation on Disease Progression of Patients With Multiple System Atrophy (MSA)[NCT02008721] | Phase 3 | 92 participants (Actual) | Interventional | 2014-01-31 | Completed | ||
| An Open Label, Single Site, 48 Week, Randomised Controlled Trial Evaluating the Safety and Efficacy of Exenatide Once-weekly in the Treatment of Patients With Multiple System Atrophy[NCT04431713] | Phase 2 | 50 participants (Anticipated) | Interventional | 2020-09-16 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for pk 11195 and Multiple System Atrophy Syndrome
| Article | Year |
|---|---|
Minocycline 1-year therapy in multiple-system-atrophy: effect on clinical symptoms and [(11)C] (R)-PK11195 PET (MEMSA-trial).
Topics: Adult; Aged; Double-Blind Method; Female; Follow-Up Studies; Humans; Isoquinolines; Magnetic Resonan | 2010 |
Minocycline 1-year therapy in multiple-system-atrophy: effect on clinical symptoms and [(11)C] (R)-PK11195 PET (MEMSA-trial).
Topics: Adult; Aged; Double-Blind Method; Female; Follow-Up Studies; Humans; Isoquinolines; Magnetic Resonan | 2010 |
Minocycline 1-year therapy in multiple-system-atrophy: effect on clinical symptoms and [(11)C] (R)-PK11195 PET (MEMSA-trial).
Topics: Adult; Aged; Double-Blind Method; Female; Follow-Up Studies; Humans; Isoquinolines; Magnetic Resonan | 2010 |
Minocycline 1-year therapy in multiple-system-atrophy: effect on clinical symptoms and [(11)C] (R)-PK11195 PET (MEMSA-trial).
Topics: Adult; Aged; Double-Blind Method; Female; Follow-Up Studies; Humans; Isoquinolines; Magnetic Resonan | 2010 |
1 other study available for pk 11195 and Multiple System Atrophy Syndrome
| Article | Year |
|---|---|
[11C](R)-PK11195 PET imaging of microglial activation in multiple system atrophy.
Topics: Aged; Carbon Radioisotopes; Humans; Isoquinolines; Male; Microglia; Middle Aged; Multiple System Atr | 2003 |