pk 11195 has been researched along with Multiple Sclerosis, Chronic Progressive in 2 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
Multiple Sclerosis, Chronic Progressive: A form of multiple sclerosis characterized by a progressive deterioration in neurologic function which is in contrast to the more typical relapsing remitting form. If the clinical course is free of distinct remissions, it is referred to as primary progressive multiple sclerosis. When the progressive decline is punctuated by acute exacerbations, it is referred to as progressive relapsing multiple sclerosis. The term secondary progressive multiple sclerosis is used when relapsing remitting multiple sclerosis evolves into the chronic progressive form. (From Ann Neurol 1994;36 Suppl:S73-S79; Adams et al., Principles of Neurology, 6th ed, pp903-914)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kang, Y | 2 |
| Pandya, S | 1 |
| Zinger, N | 1 |
| Michaelson, N | 1 |
| Gauthier, SA | 2 |
| Schlyer, D | 1 |
| Kaunzner, UW | 1 |
| Kuceyeski, A | 1 |
| Kothari, PJ | 1 |
2 other studies available for pk 11195 and Multiple Sclerosis, Chronic Progressive
| Article | Year |
|---|---|
Longitudinal change in TSPO PET imaging in progressive multiple sclerosis.
Topics: Adult; Female; Gray Matter; Humans; Isoquinolines; Longitudinal Studies; Male; Middle Aged; Multiple | 2021 |
Comparison of two different methods of image analysis for the assessment of microglial activation in patients with multiple sclerosis using (R)-[N-methyl-carbon-11]PK11195.
Topics: Adult; Brain; Female; Humans; Image Processing, Computer-Assisted; Isoquinolines; Magnetic Resonance | 2018 |