pk 11195 has been researched along with Meningioma in 2 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
Meningioma: A relatively common neoplasm of the CENTRAL NERVOUS SYSTEM that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and SPINAL CANAL. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Meningioma is one of the common brain tumors in adults." | 5.43 | The effects of PK11195 on meningioma was associated with allopregnanolone biosynthesis, which was mediated by translocator protein 18 KDa. ( Gao, ZW; Huang, JB; Liang, YJ; Lin, Q; Luo, M; Qin, Q; Zhou, L, 2016) |
| "Meningioma is one of the common brain tumors in adults." | 1.43 | The effects of PK11195 on meningioma was associated with allopregnanolone biosynthesis, which was mediated by translocator protein 18 KDa. ( Gao, ZW; Huang, JB; Liang, YJ; Lin, Q; Luo, M; Qin, Q; Zhou, L, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, ZW | 1 |
| Huang, JB | 1 |
| Lin, Q | 1 |
| Qin, Q | 1 |
| Liang, YJ | 1 |
| Zhou, L | 1 |
| Luo, M | 1 |
| Cornu, P | 1 |
| Benavides, J | 1 |
| Scatton, B | 1 |
| Hauw, JJ | 1 |
| Philippon, J | 1 |
2 other studies available for pk 11195 and Meningioma
| Article | Year |
|---|---|
The effects of PK11195 on meningioma was associated with allopregnanolone biosynthesis, which was mediated by translocator protein 18 KDa.
Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Isoquin | 2016 |
Increase in omega 3 (peripheral-type benzodiazepine) binding site densities in different types of human brain tumours. A quantitative autoradiography study.
Topics: Astrocytoma; Autoradiography; Biomarkers, Tumor; Brain; Brain Neoplasms; Cerebellar Neoplasms; Gliom | 1992 |