pk 11195 has been researched along with Lymphoma in 4 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
Lymphoma: A general term for various neoplastic diseases of the lymphoid tissue.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study we characterized a saturable and high affinity binding site for [3H]Pk 11195 (isoquinoline carboxamide derivative) on human lymphocytes and different lymphoma cell lines." | 3.68 | Characterization of peripheral-type benzodiazepine binding sites on human lymphocytes and lymphoma cell lines and their role in cell growth. ( Alexander, BE; Klotz, U; Roller, E, 1992) |
| "[3H]Ro 5-4864 binds to Nb 2 node lymphoma cells in a specific saturable and reversible fashion." | 3.67 | Peripheral benzodiazepine binding sites in Nb 2 node lymphoma cells: effects on prolactin-stimulated proliferation and ornithine decarboxylase activity. ( Duerson, KC; Gerrish, KE; Laird, HE; Putnam, CW; Russell, DH, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fennell, DA | 1 |
| Corbo, M | 1 |
| Pallaska, A | 1 |
| Cotter, FE | 1 |
| Alexander, BE | 1 |
| Roller, E | 1 |
| Klotz, U | 1 |
| Cornu, P | 1 |
| Benavides, J | 1 |
| Scatton, B | 1 |
| Hauw, JJ | 1 |
| Philippon, J | 1 |
| Laird, HE | 1 |
| Gerrish, KE | 1 |
| Duerson, KC | 1 |
| Putnam, CW | 1 |
| Russell, DH | 1 |
4 other studies available for pk 11195 and Lymphoma
| Article | Year |
|---|---|
Bcl-2 resistant mitochondrial toxicity mediated by the isoquinoline carboxamide PK11195 involves de novo generation of reactive oxygen species.
Topics: Antineoplastic Agents; Cell Death; Dose-Response Relationship, Drug; Genes, bcl-2; HL-60 Cells; Huma | 2001 |
Characterization of peripheral-type benzodiazepine binding sites on human lymphocytes and lymphoma cell lines and their role in cell growth.
Topics: Adult; Binding Sites; Cell Division; Cell Line; Dose-Response Relationship, Drug; Female; Humans; Is | 1992 |
Increase in omega 3 (peripheral-type benzodiazepine) binding site densities in different types of human brain tumours. A quantitative autoradiography study.
Topics: Astrocytoma; Autoradiography; Biomarkers, Tumor; Brain; Brain Neoplasms; Cerebellar Neoplasms; Gliom | 1992 |
Peripheral benzodiazepine binding sites in Nb 2 node lymphoma cells: effects on prolactin-stimulated proliferation and ornithine decarboxylase activity.
Topics: Benzodiazepinones; Cell Division; Clonazepam; Humans; Isoquinolines; Kinetics; Lymph Nodes; Lymphoma | 1989 |