pk 11195 has been researched along with Leukemia, Myeloid, Acute in 2 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Walter, RB | 1 |
| Pirga, JL | 1 |
| Cronk, MR | 1 |
| Mayer, S | 1 |
| Appelbaum, FR | 1 |
| Banker, DE | 1 |
| Ishiguro, K | 1 |
| Taft, WC | 1 |
| DeLorenzo, RJ | 1 |
| Sartorelli, AC | 1 |
2 other studies available for pk 11195 and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
PK11195, a peripheral benzodiazepine receptor (pBR) ligand, broadly blocks drug efflux to chemosensitize leukemia and myeloma cells by a pBR-independent, direct transporter-modulating mechanism.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Bindi | 2005 |
The role of benzodiazepine receptors in the induction of differentiation of HL-60 leukemia cells by benzodiazepines and purines.
Topics: Benzodiazepines; Benzodiazepinones; Cell Differentiation; Cell Line; Humans; Isoquinolines; Leukemia | 1987 |