pk 11195 has been researched along with Infarction, Middle Cerebral Artery in 7 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rats were subjected to permanent middle cerebral artery occlusion (pMCAO) by the macrosphere model and monitored by MRI and PET for 28 or 56 days, followed by immunohistochemical endpoint analysis." | 1.42 | In vivo analysis of neuroinflammation in the late chronic phase after experimental stroke. ( Backes, H; Fink, GR; Graf, R; Hoehn, M; Neumaier, B; Rueger, MA; Schroeter, M; Walberer, M; Walter, HL; Wiedermann, D, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhong, YH | 1 |
| Dhawan, J | 1 |
| Kovoor, JA | 1 |
| Sullivan, J | 1 |
| Zhang, WX | 1 |
| Choi, D | 1 |
| Biegon, A | 1 |
| Walter, HL | 1 |
| Walberer, M | 2 |
| Rueger, MA | 2 |
| Backes, H | 2 |
| Wiedermann, D | 1 |
| Hoehn, M | 2 |
| Neumaier, B | 2 |
| Graf, R | 2 |
| Fink, GR | 2 |
| Schroeter, M | 2 |
| Fukumoto, D | 1 |
| Hosoya, T | 1 |
| Nishiyama, S | 1 |
| Harada, N | 1 |
| Iwata, H | 1 |
| Yamamoto, S | 1 |
| Tsukada, H | 1 |
| Hughes, JL | 1 |
| Jones, PS | 1 |
| Beech, JS | 1 |
| Wang, D | 2 |
| Menon, DK | 2 |
| Aigbirhio, FI | 1 |
| Fryer, TD | 1 |
| Baron, JC | 2 |
| Muesken, S | 1 |
| Jantzen, SU | 1 |
| Schnakenburg, K | 1 |
| Katchanov, J | 1 |
| Waeber, C | 1 |
| Gertz, K | 1 |
| Gietz, A | 1 |
| Winter, B | 1 |
| Brück, W | 1 |
| Dirnagl, U | 1 |
| Veh, RW | 1 |
| Endres, M | 1 |
| Price, CJ | 1 |
| Guadagno, JV | 1 |
| Cleij, M | 1 |
| Fryer, T | 1 |
| Aigbirhio, F | 1 |
| Warburton, EA | 1 |
7 other studies available for pk 11195 and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Aromatase and neuroinflammation in rat focal brain ischemia.
Topics: Animals; Aromatase; Brain; Chelating Agents; Ethylenediamines; Excitatory Amino Acid Antagonists; Hu | 2017 |
In vivo analysis of neuroinflammation in the late chronic phase after experimental stroke.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Brain; Brain Ischemia; Calcium-Bin | 2015 |
Multiparametric assessment of acute and subacute ischemic neuronal damage: a small animal positron emission tomography study with rat photochemically induced thrombosis model.
Topics: Animals; Carbon Radioisotopes; Fluorodeoxyglucose F18; Immunohistochemistry; Infarction, Middle Cere | 2011 |
A microPET study of the regional distribution of [11C]-PK11195 binding following temporary focal cerebral ischemia in the rat. Correlation with post mortem mapping of microglia activation.
Topics: Animals; Brain Mapping; CD11b Antigen; Cerebrovascular Circulation; Image Processing, Computer-Assis | 2012 |
Effects of minocycline on endogenous neural stem cells after experimental stroke.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Anti-Bacterial Agents; Brain Infarction; Brain | 2012 |
Selective neuronal vulnerability following mild focal brain ischemia in the mouse.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antidotes; Antineoplastic Agents; Autoradiography; Binding Sit | 2003 |
Intrinsic activated microglia map to the peri-infarct zone in the subacute phase of ischemic stroke.
Topics: Acute Disease; Adult; Aged; Brain Ischemia; Carbon Radioisotopes; Female; Humans; Infarction, Middle | 2006 |