pk 11195 has been researched along with Hyperactivity, Motor in 1 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, rats received intraperitoneal kainic acid injections, which are known to cause seizures, neurodegeneration, hyperactivity, gliosis, and a fivefold increase in PBR ligand binding density in the hippocampus." | 7.71 | PK 11195 attenuates kainic acid-induced seizures and alterations in peripheral-type benzodiazepine receptor (PBR) protein components in the rat brain. ( Gavish, M; Leschiner, S; Spanier, I; Veenman, L; Weisinger, G; Weizman, A, 2002) |
| " In the present study, rats received intraperitoneal kainic acid injections, which are known to cause seizures, neurodegeneration, hyperactivity, gliosis, and a fivefold increase in PBR ligand binding density in the hippocampus." | 3.71 | PK 11195 attenuates kainic acid-induced seizures and alterations in peripheral-type benzodiazepine receptor (PBR) protein components in the rat brain. ( Gavish, M; Leschiner, S; Spanier, I; Veenman, L; Weisinger, G; Weizman, A, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Veenman, L | 1 |
| Leschiner, S | 1 |
| Spanier, I | 1 |
| Weisinger, G | 1 |
| Weizman, A | 1 |
| Gavish, M | 1 |
1 other study available for pk 11195 and Hyperactivity, Motor
| Article | Year |
|---|---|
PK 11195 attenuates kainic acid-induced seizures and alterations in peripheral-type benzodiazepine receptor (PBR) protein components in the rat brain.
Topics: Animals; Behavior, Animal; Binding, Competitive; Blotting, Western; Hippocampus; Hyperkinesis; Isoqu | 2002 |