pk 11195 has been researched along with Fibromyalgia in 2 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
Fibromyalgia: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fibromyalgia (FM) and complex regional pain syndrome (CRPS) share many pathological mechanisms related to chronic pain and neuroinflammation, which may contribute to the multifactorial pathological mechanisms in both FM and CRPS." | 1.62 | Abnormal neuroinflammation in fibromyalgia and CRPS using [11C]-(R)-PK11195 PET. ( Cheon, GJ; Choi, SH; Jang, JH; Jung, YH; Kang, DH; Lee, D; Lee, JS; Lee, JY; Lee, WJ; Moon, JY; Seo, S, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Seo, S | 1 |
| Jung, YH | 1 |
| Lee, D | 1 |
| Lee, WJ | 1 |
| Jang, JH | 1 |
| Lee, JY | 1 |
| Choi, SH | 1 |
| Moon, JY | 1 |
| Lee, JS | 1 |
| Cheon, GJ | 1 |
| Kang, DH | 1 |
| Bazzichi, L | 1 |
| Giannaccini, G | 1 |
| Betti, L | 1 |
| Italiani, P | 1 |
| Fabbrini, L | 1 |
| Defeo, F | 1 |
| Giacomelli, C | 1 |
| Giuliano, T | 1 |
| Rossi, A | 1 |
| Uccelli, A | 1 |
| Giusti, L | 1 |
| Mascia, G | 1 |
| Lucacchini, A | 1 |
| Bombardieri, S | 1 |
2 other studies available for pk 11195 and Fibromyalgia
| Article | Year |
|---|---|
Abnormal neuroinflammation in fibromyalgia and CRPS using [11C]-(R)-PK11195 PET.
Topics: Adult; Brain; Carbon Radioisotopes; Case-Control Studies; Complex Regional Pain Syndromes; Encephali | 2021 |
Peripheral benzodiazepine receptors on platelets of fibromyalgic patients.
Topics: Blood Platelets; Cell Membrane; Female; Fibromyalgia; Humans; Isoquinolines; Middle Aged; Receptors, | 2006 |