Page last updated: 2024-10-21

pk 11195 and Fibromyalgia

pk 11195 has been researched along with Fibromyalgia in 2 studies

PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine

Fibromyalgia: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)

Research Excerpts

ExcerptRelevanceReference
"Fibromyalgia (FM) and complex regional pain syndrome (CRPS) share many pathological mechanisms related to chronic pain and neuroinflammation, which may contribute to the multifactorial pathological mechanisms in both FM and CRPS."1.62Abnormal neuroinflammation in fibromyalgia and CRPS using [11C]-(R)-PK11195 PET. ( Cheon, GJ; Choi, SH; Jang, JH; Jung, YH; Kang, DH; Lee, D; Lee, JS; Lee, JY; Lee, WJ; Moon, JY; Seo, S, 2021)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Seo, S1
Jung, YH1
Lee, D1
Lee, WJ1
Jang, JH1
Lee, JY1
Choi, SH1
Moon, JY1
Lee, JS1
Cheon, GJ1
Kang, DH1
Bazzichi, L1
Giannaccini, G1
Betti, L1
Italiani, P1
Fabbrini, L1
Defeo, F1
Giacomelli, C1
Giuliano, T1
Rossi, A1
Uccelli, A1
Giusti, L1
Mascia, G1
Lucacchini, A1
Bombardieri, S1

Other Studies

2 other studies available for pk 11195 and Fibromyalgia

ArticleYear
Abnormal neuroinflammation in fibromyalgia and CRPS using [11C]-(R)-PK11195 PET.
    PloS one, 2021, Volume: 16, Issue:2

    Topics: Adult; Brain; Carbon Radioisotopes; Case-Control Studies; Complex Regional Pain Syndromes; Encephali

2021
Peripheral benzodiazepine receptors on platelets of fibromyalgic patients.
    Clinical biochemistry, 2006, Volume: 39, Issue:9

    Topics: Blood Platelets; Cell Membrane; Female; Fibromyalgia; Humans; Isoquinolines; Middle Aged; Receptors,

2006