pk 11195 has been researched along with Epilepsy, Temporal Lobe in 2 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
Epilepsy, Temporal Lobe: A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the TEMPORAL LOBE, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic. (From Adams et al., Principles of Neurology, 6th ed, p321).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bogdanović, RM | 1 |
| Syvänen, S | 1 |
| Michler, C | 1 |
| Russmann, V | 1 |
| Eriksson, J | 1 |
| Windhorst, AD | 1 |
| Lammertsma, AA | 1 |
| de Lange, EC | 1 |
| Voskuyl, RA | 1 |
| Potschka, H | 1 |
| Sauvageau, A | 1 |
| Desjardins, P | 1 |
| Lozeva, V | 1 |
| Rose, C | 1 |
| Hazell, AS | 1 |
| Bouthillier, A | 1 |
| Butterwort, RF | 1 |
2 other studies available for pk 11195 and Epilepsy, Temporal Lobe
| Article | Year |
|---|---|
(R)-[11C]PK11195 brain uptake as a biomarker of inflammation and antiepileptic drug resistance: evaluation in a rat epilepsy model.
Topics: Animals; Anticonvulsants; Brain; Carbon Radioisotopes; Carrier Proteins; Chronic Disease; Disease Mo | 2014 |
Increased expression of "peripheral-type" benzodiazepine receptors in human temporal lobe epilepsy: implications for PET imaging of hippocampal sclerosis.
Topics: Epilepsy, Temporal Lobe; Hippocampus; Humans; Immunohistochemistry; In Vitro Techniques; Isoquinolin | 2002 |