Page last updated: 2024-10-21

pk 11195 and Di Guglielmo Disease

pk 11195 has been researched along with Di Guglielmo Disease in 2 studies

PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine

Research Excerpts

ExcerptRelevanceReference
"ALA-induced PPIX accumulation in erythroleukemia cells (UT-7 and K562) was impaired by PK 11195, a competitive inhibitor of both transmembrane proteins TSPO (1 and 2)."1.56TSPO2 translocates 5-aminolevulinic acid into human erythroleukemia cells. ( Gouya, L; Hattab, C; Lacapere, JJ; Lefevre, SD; Manceau, H; Mirmiran, A; Ostuni, MA; Peoc'h, K; Puy, H; Schmitt, C; Sugier, HR, 2020)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Manceau, H1
Lefevre, SD1
Mirmiran, A1
Hattab, C1
Sugier, HR1
Schmitt, C1
Peoc'h, K1
Puy, H1
Ostuni, MA1
Gouya, L1
Lacapere, JJ1
Taketani, S1
Kohno, H1
Okuda, M1
Furukawa, T1
Tokunaga, R1

Other Studies

2 other studies available for pk 11195 and Di Guglielmo Disease

ArticleYear
TSPO2 translocates 5-aminolevulinic acid into human erythroleukemia cells.
    Biology of the cell, 2020, Volume: 112, Issue:4

    Topics: Aminolevulinic Acid; Biological Transport; Cell Membrane; Green Fluorescent Proteins; Humans; Isoqui

2020
Induction of peripheral-type benzodiazepine receptors during differentiation of mouse erythroleukemia cells. A possible involvement of these receptors in heme biosynthesis.
    The Journal of biological chemistry, 1994, Mar-11, Volume: 269, Issue:10

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Blotting, Western; Cloning, Molecular; C

1994