Page last updated: 2024-10-21

pk 11195 and Depressive Disorder

pk 11195 has been researched along with Depressive Disorder in 3 studies

PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine

Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.

Research Excerpts

ExcerptRelevanceReference
"PK 11195 is a selective ligand for the peripheral-type benzodiazepine binding sites which exhibits anti-conflict activity in animals."1.28Pilot study of PK 11195, a selective ligand for the peripheral-type benzodiazepine binding sites, in inpatients with anxious or depressive symptomatology. ( Ansseau, M; Cerfontaine, JL; Papart, P; von Frenckell, R, 1991)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kudryashov, NV1
Kalinina, TS1
Shimshirt, AA1
Korolev, AO1
Volkova, AV1
Voronina, TA1
Marazziti, D1
Dell'Osso, B1
Baroni, S1
Masala, I1
Di Nasso, E1
Giannaccini, G1
Conti, L1
Ansseau, M1
von Frenckell, R1
Cerfontaine, JL1
Papart, P1

Other Studies

3 other studies available for pk 11195 and Depressive Disorder

ArticleYear
Antidepressant-like effect of fluoxetine may depend on translocator protein activity and pretest session duration in forced swimming test in mice.
    Behavioural pharmacology, 2018, Volume: 29, Issue:4

    Topics: Animals; Antidepressive Agents; Depression; Depressive Disorder; Disease Models, Animal; Fluoxetine;

2018
Decreased density of peripheral benzodiazepine receptors in psychiatric patients after a suicide attempt.
    Life sciences, 2005, Nov-12, Volume: 77, Issue:26

    Topics: Adolescent; Adult; Antineoplastic Agents; Brain; Depressive Disorder; Female; Hormones; Humans; Isoq

2005
Pilot study of PK 11195, a selective ligand for the peripheral-type benzodiazepine binding sites, in inpatients with anxious or depressive symptomatology.
    Pharmacopsychiatry, 1991, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Anxiety Disorders; Depressive Disorder; Female; Humans; Isoquinolines; Ligands; M

1991