pk 11195 has been researched along with Coronary Disease in 2 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clonazepam and PK 11209 were both inactive in this regard." | 1.28 | Interactions between peripheral-type benzodiazepine receptor ligands and an activator of voltage-operated calcium channels. ( Abraham, S; Bolger, GT; Oz, N; Weissman, BA, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bolger, GT | 1 |
| Abraham, S | 1 |
| Oz, N | 1 |
| Weissman, BA | 1 |
| Mestre, M | 1 |
| Bouetard, G | 1 |
| Uzan, A | 1 |
| Gueremy, C | 1 |
| Renault, C | 1 |
| Dubroeucq, MC | 1 |
| Le Fur, G | 1 |
2 other studies available for pk 11195 and Coronary Disease
| Article | Year |
|---|---|
Interactions between peripheral-type benzodiazepine receptor ligands and an activator of voltage-operated calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
PK 11195, an antagonist of peripheral benzodiazepine receptors, reduces ventricular arrhythmias during myocardial ischemia and reperfusion in the dog.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Coronary Disease; Dogs; Dose-Response Relationship, | 1985 |