pk 11195 has been researched along with Complex Regional Pain Syndromes in 2 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
Complex Regional Pain Syndromes: Conditions characterized by pain involving an extremity or other body region, HYPERESTHESIA, and localized autonomic dysfunction following injury to soft tissue or nerve. The pain is usually associated with ERYTHEMA; SKIN TEMPERATURE changes, abnormal sudomotor activity (i.e., changes in sweating due to altered sympathetic innervation) or edema. The degree of pain and other manifestations is out of proportion to that expected from the inciting event. Two subtypes of this condition have been described: type I; (REFLEX SYMPATHETIC DYSTROPHY) and type II; (CAUSALGIA). (From Pain 1995 Oct;63(1):127-33)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fibromyalgia (FM) and complex regional pain syndrome (CRPS) share many pathological mechanisms related to chronic pain and neuroinflammation, which may contribute to the multifactorial pathological mechanisms in both FM and CRPS." | 1.62 | Abnormal neuroinflammation in fibromyalgia and CRPS using [11C]-(R)-PK11195 PET. ( Cheon, GJ; Choi, SH; Jang, JH; Jung, YH; Kang, DH; Lee, D; Lee, JS; Lee, JY; Lee, WJ; Moon, JY; Seo, S, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Seo, S | 1 |
| Jung, YH | 2 |
| Lee, D | 1 |
| Lee, WJ | 2 |
| Jang, JH | 2 |
| Lee, JY | 2 |
| Choi, SH | 2 |
| Moon, JY | 1 |
| Lee, JS | 1 |
| Cheon, GJ | 1 |
| Kang, DH | 2 |
| Kim, H | 1 |
| Jeon, SY | 1 |
| Kwon, JM | 1 |
| Kim, YC | 1 |
2 other studies available for pk 11195 and Complex Regional Pain Syndromes
| Article | Year |
|---|---|
Abnormal neuroinflammation in fibromyalgia and CRPS using [11C]-(R)-PK11195 PET.
Topics: Adult; Brain; Carbon Radioisotopes; Case-Control Studies; Complex Regional Pain Syndromes; Encephali | 2021 |
Brain Metabolites and Peripheral Biomarkers Associated with Neuroinflammation in Complex Regional Pain Syndrome Using [11C]-(R)-PK11195 Positron Emission Tomography and Magnetic Resonance Spectroscopy: A Pilot Study.
Topics: Adult; Basophils; Biomarkers; Blood Glucose; Brain; Carbon Dioxide; Carbon Radioisotopes; Complex Re | 2019 |