pk 11195 has been researched along with Cognition Disorders in 7 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Longitudinally, Alzheimer's disease subjects showed an increase in microglial activation." | 1.46 | An early and late peak in microglial activation in Alzheimer's disease trajectory. ( Brooks, DJ; Edison, P; Fan, Z; Okello, A, 2017) |
| "Inflammation in Alzheimer's disease (AD) may be assessed using (R)-[(11)C]PK11195 and positron emission tomography." | 1.34 | Evaluation of reference regions for (R)-[(11)C]PK11195 studies in Alzheimer's disease and mild cognitive impairment. ( Boellaard, R; Jonker, C; Kloet, RW; Kropholler, MA; Lammertsma, AA; Lubberink, MJ; Scheltens, P; Schuitemaker, A; van Berckel, BN, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fan, Z | 1 |
| Brooks, DJ | 3 |
| Okello, A | 2 |
| Edison, P | 2 |
| Archer, HA | 1 |
| Turkheimer, FE | 2 |
| Kennedy, J | 1 |
| Bullock, R | 1 |
| Walker, Z | 1 |
| Kennedy, A | 1 |
| Fox, N | 1 |
| Rossor, M | 1 |
| Wiley, CA | 1 |
| Lopresti, BJ | 1 |
| Venneti, S | 1 |
| Price, J | 1 |
| Klunk, WE | 1 |
| DeKosky, ST | 1 |
| Mathis, CA | 1 |
| Ramlackhansingh, AF | 1 |
| Greenwood, RJ | 1 |
| Bose, SK | 1 |
| Kinnunen, KM | 1 |
| Gentleman, S | 1 |
| Heckemann, RA | 1 |
| Gunanayagam, K | 1 |
| Gelosa, G | 1 |
| Sharp, DJ | 1 |
| Heiss, WD | 1 |
| Zimmermann-Meinzingen, S | 1 |
| Obernier, JA | 1 |
| White, AM | 1 |
| Swartzwelder, HS | 1 |
| Crews, FT | 1 |
| Kropholler, MA | 1 |
| Boellaard, R | 1 |
| van Berckel, BN | 1 |
| Schuitemaker, A | 1 |
| Kloet, RW | 1 |
| Lubberink, MJ | 1 |
| Jonker, C | 1 |
| Scheltens, P | 1 |
| Lammertsma, AA | 1 |
1 review available for pk 11195 and Cognition Disorders
| Article | Year |
|---|---|
PET imaging in the differential diagnosis of vascular dementia.
Topics: Cerebral Cortex; Cognition Disorders; Dementia, Vascular; Diagnosis, Differential; Drugs, Chinese He | 2012 |
6 other studies available for pk 11195 and Cognition Disorders
| Article | Year |
|---|---|
An early and late peak in microglial activation in Alzheimer's disease trajectory.
Topics: Aged; Alzheimer Disease; Aniline Compounds; Antineoplastic Agents; Brain Mapping; Carbon Radioisotop | 2017 |
Microglial activation and amyloid deposition in mild cognitive impairment: a PET study.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Benzothiazoles; Brain Mapping; Ca | 2009 |
Carbon 11-labeled Pittsburgh Compound B and carbon 11-labeled (R)-PK11195 positron emission tomographic imaging in Alzheimer disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Antineoplastic | 2009 |
Inflammation after trauma: microglial activation and traumatic brain injury.
Topics: Adult; Amnesia; Brain Injuries; Cluster Analysis; Cognition Disorders; Diffusion Tensor Imaging; Edu | 2011 |
Cognitive deficits and CNS damage after a 4-day binge ethanol exposure in rats.
Topics: Animals; Central Nervous System; Cognition; Cognition Disorders; Copper; Ethanol; Isoquinolines; Mal | 2002 |
Evaluation of reference regions for (R)-[(11)C]PK11195 studies in Alzheimer's disease and mild cognitive impairment.
Topics: Adult; Aged; Algorithms; Alzheimer Disease; Antineoplastic Agents; Blood Volume; Cluster Analysis; C | 2007 |