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pk 11195 and Cirrhosis

pk 11195 has been researched along with Cirrhosis in 2 studies

PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine

Research Excerpts

ExcerptRelevanceReference
" We examined the biochemical and ultrastructural alterations in rat liver following experimentally induced acute hepatic porphyria, as well as the effects of the administration of a selective PBR ligand, PK 11195."7.69PK 11195 aggravates 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced hepatic porphyria in rats. ( Coleman, R; Fonia, O; Gavish, M; Kaganovskaya, E; Weizman, R, 1996)
" We examined the biochemical and ultrastructural alterations in rat liver following experimentally induced acute hepatic porphyria, as well as the effects of the administration of a selective PBR ligand, PK 11195."3.69PK 11195 aggravates 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced hepatic porphyria in rats. ( Coleman, R; Fonia, O; Gavish, M; Kaganovskaya, E; Weizman, R, 1996)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fonia, O1
Weizman, R1
Coleman, R1
Kaganovskaya, E1
Gavish, M1
Lavoie, J1
Layrargues, GP1
Butterworth, RF1

Other Studies

2 other studies available for pk 11195 and Cirrhosis

ArticleYear
PK 11195 aggravates 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced hepatic porphyria in rats.
    Hepatology (Baltimore, Md.), 1996, Volume: 24, Issue:3

    Topics: Animals; Bile Canaliculi; Dicarbethoxydihydrocollidine; Fibrosis; Isoquinolines; Liver; Male; Micros

1996
Increased densities of peripheral-type benzodiazepine receptors in brain autopsy samples from cirrhotic patients with hepatic encephalopathy.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:5

    Topics: Binding Sites; Binding, Competitive; Brain; Fibrosis; Hepatic Encephalopathy; Humans; Isoquinolines;

1990