pk 11195 and Cirrhosis studies

pk 11195 and Cirrhosis

pk 11195 has been researched along with Cirrhosis in 2 studies

PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine

Research Excerpts

Excerpt	Relevance	Reference
" We examined the biochemical and ultrastructural alterations in rat liver following experimentally induced acute hepatic porphyria, as well as the effects of the administration of a selective PBR ligand, PK 11195."	7.69	PK 11195 aggravates 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced hepatic porphyria in rats. ( Coleman, R; Fonia, O; Gavish, M; Kaganovskaya, E; Weizman, R, 1996)
" We examined the biochemical and ultrastructural alterations in rat liver following experimentally induced acute hepatic porphyria, as well as the effects of the administration of a selective PBR ligand, PK 11195."	3.69	PK 11195 aggravates 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced hepatic porphyria in rats. ( Coleman, R; Fonia, O; Gavish, M; Kaganovskaya, E; Weizman, R, 1996)

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

2 (100.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Fonia, O	1
Weizman, R	1
Coleman, R	1
Kaganovskaya, E	1
Gavish, M	1
Lavoie, J	1
Layrargues, GP	1
Butterworth, RF	1

Studies

Fonia, O

Weizman, R

Coleman, R

Kaganovskaya, E

Gavish, M

Lavoie, J

Layrargues, GP

Butterworth, RF

Other Studies

2 other studies available for pk 11195 and Cirrhosis

Article	Year
PK 11195 aggravates 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced hepatic porphyria in rats. Hepatology (Baltimore, Md.), 1996, Volume: 24, Issue:3 Topics: Animals; Bile Canaliculi; Dicarbethoxydihydrocollidine; Fibrosis; Isoquinolines; Liver; Male; Micros	1996
Increased densities of peripheral-type benzodiazepine receptors in brain autopsy samples from cirrhotic patients with hepatic encephalopathy. Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:5 Topics: Binding Sites; Binding, Competitive; Brain; Fibrosis; Hepatic Encephalopathy; Humans; Isoquinolines;	1990

Article

Year

PK 11195 aggravates 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced hepatic porphyria in rats.

Hepatology (Baltimore, Md.), 1996, Volume: 24, Issue:3

Topics: Animals; Bile Canaliculi; Dicarbethoxydihydrocollidine; Fibrosis; Isoquinolines; Liver; Male; Micros

1996

Increased densities of peripheral-type benzodiazepine receptors in brain autopsy samples from cirrhotic patients with hepatic encephalopathy.

Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:5

Topics: Binding Sites; Binding, Competitive; Brain; Fibrosis; Hepatic Encephalopathy; Humans; Isoquinolines;

1990