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pk 11195 and Cerebral Palsy

pk 11195 has been researched along with Cerebral Palsy in 1 studies

PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine

Cerebral Palsy: A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kannan, S1
Saadani-Makki, F1
Balakrishnan, B1
Chakraborty, P1
Janisse, J1
Lu, X1
Muzik, O1
Romero, R1
Chugani, DC1

Other Studies

1 other study available for pk 11195 and Cerebral Palsy

ArticleYear
Magnitude of [(11)C]PK11195 binding is related to severity of motor deficits in a rabbit model of cerebral palsy induced by intrauterine endotoxin exposure.
    Developmental neuroscience, 2011, Volume: 33, Issue:3-4

    Topics: Animals; Animals, Newborn; Antineoplastic Agents; Behavior, Animal; Brain; Carbon Radioisotopes; Cer

2011