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pk 11195 and Cell Transformation, Neoplastic

pk 11195 has been researched along with Cell Transformation, Neoplastic in 2 studies

PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine

Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

Research Excerpts

ExcerptRelevanceReference
"TSPO in gliomas was expressed predominantly by neoplastic cells, and its expression correlated positively with BPND in the tumors."1.42The 18-kDa mitochondrial translocator protein in human gliomas: an 11C-(R)PK11195 PET imaging and neuropathology study. ( Brodbelt, A; Coope, DJ; Du Plessis, D; Durrenberger, PF; Gerhard, A; Herholz, K; Hinz, R; Jackson, A; Janczar, K; Karabatsou, K; Roncaroli, F; Su, Z; Thompson, G; Turkheimer, FE, 2015)
"Despite the high incidence of chronic lymphocytic leukemia (CLL), metabolism of CLL cells remains a relatively unexplored area."1.40Mitochondrial metabolism contributes to oxidative stress and reveals therapeutic targets in chronic lymphocytic leukemia. ( Berger, J; Bricks, J; Bruns, H; Eckart, MJ; Giessl, A; Hofmann, AD; Jitschin, R; Mackensen, A; Mougiakakos, D; Saul, D, 2014)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jitschin, R1
Hofmann, AD1
Bruns, H1
Giessl, A1
Bricks, J1
Berger, J1
Saul, D1
Eckart, MJ1
Mackensen, A1
Mougiakakos, D1
Su, Z1
Roncaroli, F1
Durrenberger, PF1
Coope, DJ1
Karabatsou, K1
Hinz, R1
Thompson, G1
Turkheimer, FE1
Janczar, K1
Du Plessis, D1
Brodbelt, A1
Jackson, A1
Gerhard, A1
Herholz, K1

Other Studies

2 other studies available for pk 11195 and Cell Transformation, Neoplastic

ArticleYear
Mitochondrial metabolism contributes to oxidative stress and reveals therapeutic targets in chronic lymphocytic leukemia.
    Blood, 2014, Apr-24, Volume: 123, Issue:17

    Topics: Adenosine Triphosphatases; Aged; Aged, 80 and over; Antineoplastic Agents; Antioxidants; Cell Separa

2014
The 18-kDa mitochondrial translocator protein in human gliomas: an 11C-(R)PK11195 PET imaging and neuropathology study.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2015, Volume: 56, Issue:4

    Topics: Adult; Antineoplastic Agents; Astrocytoma; Biomarkers, Tumor; Blood-Brain Barrier; Brain; Brain Neop

2015