pk 11195 has been researched along with Cell Transformation, Neoplastic in 2 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "TSPO in gliomas was expressed predominantly by neoplastic cells, and its expression correlated positively with BPND in the tumors." | 1.42 | The 18-kDa mitochondrial translocator protein in human gliomas: an 11C-(R)PK11195 PET imaging and neuropathology study. ( Brodbelt, A; Coope, DJ; Du Plessis, D; Durrenberger, PF; Gerhard, A; Herholz, K; Hinz, R; Jackson, A; Janczar, K; Karabatsou, K; Roncaroli, F; Su, Z; Thompson, G; Turkheimer, FE, 2015) |
| "Despite the high incidence of chronic lymphocytic leukemia (CLL), metabolism of CLL cells remains a relatively unexplored area." | 1.40 | Mitochondrial metabolism contributes to oxidative stress and reveals therapeutic targets in chronic lymphocytic leukemia. ( Berger, J; Bricks, J; Bruns, H; Eckart, MJ; Giessl, A; Hofmann, AD; Jitschin, R; Mackensen, A; Mougiakakos, D; Saul, D, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jitschin, R | 1 |
| Hofmann, AD | 1 |
| Bruns, H | 1 |
| Giessl, A | 1 |
| Bricks, J | 1 |
| Berger, J | 1 |
| Saul, D | 1 |
| Eckart, MJ | 1 |
| Mackensen, A | 1 |
| Mougiakakos, D | 1 |
| Su, Z | 1 |
| Roncaroli, F | 1 |
| Durrenberger, PF | 1 |
| Coope, DJ | 1 |
| Karabatsou, K | 1 |
| Hinz, R | 1 |
| Thompson, G | 1 |
| Turkheimer, FE | 1 |
| Janczar, K | 1 |
| Du Plessis, D | 1 |
| Brodbelt, A | 1 |
| Jackson, A | 1 |
| Gerhard, A | 1 |
| Herholz, K | 1 |
2 other studies available for pk 11195 and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Mitochondrial metabolism contributes to oxidative stress and reveals therapeutic targets in chronic lymphocytic leukemia.
Topics: Adenosine Triphosphatases; Aged; Aged, 80 and over; Antineoplastic Agents; Antioxidants; Cell Separa | 2014 |
The 18-kDa mitochondrial translocator protein in human gliomas: an 11C-(R)PK11195 PET imaging and neuropathology study.
Topics: Adult; Antineoplastic Agents; Astrocytoma; Biomarkers, Tumor; Blood-Brain Barrier; Brain; Brain Neop | 2015 |