pk 11195 has been researched along with Carotid Artery Diseases in 4 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
Carotid Artery Diseases: Pathological conditions involving the CAROTID ARTERIES, including the common, internal, and external carotid arteries. ATHEROSCLEROSIS and TRAUMA are relatively frequent causes of carotid artery pathology.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Six patients diagnosed as carotid atherosclerosis underwent endarterectomy." | 5.35 | Increased peripheral benzodiazepine receptors in arterial plaque of patients with atherosclerosis: an autoradiographic study with [(3)H]PK 11195. ( Fujimura, Y; Fujita, M; Hwang, PM; Imaizumi, M; Innis, RB; Kozloff, L; Trout Iii, H, 2008) |
| "Six patients diagnosed as carotid atherosclerosis underwent endarterectomy." | 1.35 | Increased peripheral benzodiazepine receptors in arterial plaque of patients with atherosclerosis: an autoradiographic study with [(3)H]PK 11195. ( Fujimura, Y; Fujita, M; Hwang, PM; Imaizumi, M; Innis, RB; Kozloff, L; Trout Iii, H, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bird, JL | 1 |
| Izquierdo-Garcia, D | 1 |
| Davies, JR | 1 |
| Rudd, JH | 1 |
| Probst, KC | 1 |
| Figg, N | 1 |
| Clark, JC | 1 |
| Weissberg, PL | 1 |
| Davenport, AP | 1 |
| Warburton, EA | 1 |
| Gaemperli, O | 1 |
| Shalhoub, J | 1 |
| Owen, DR | 1 |
| Lamare, F | 1 |
| Johansson, S | 1 |
| Fouladi, N | 1 |
| Davies, AH | 1 |
| Rimoldi, OE | 1 |
| Camici, PG | 1 |
| Kaski, JC | 1 |
| Fujimura, Y | 1 |
| Hwang, PM | 1 |
| Trout Iii, H | 1 |
| Kozloff, L | 1 |
| Imaizumi, M | 1 |
| Innis, RB | 1 |
| Fujita, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| In Vivo Molecular Imaging (MRI) of Atherothrombotic Lesions[NCT01418313] | 886 participants (Actual) | Observational | 2011-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for pk 11195 and Carotid Artery Diseases
| Article | Year |
|---|---|
Evaluation of translocator protein quantification as a tool for characterising macrophage burden in human carotid atherosclerosis.
Topics: Aged; Atherosclerosis; Carotid Arteries; Carotid Artery Diseases; Constriction, Pathologic; Female; | 2010 |
Imaging intraplaque inflammation in carotid atherosclerosis with 11C-PK11195 positron emission tomography/computed tomography.
Topics: Aged; Autoradiography; Carbon Radioisotopes; Carotid Artery Diseases; Carotid Stenosis; Female; Huma | 2012 |
Molecular imaging of inflammation for detection of vulnerable atheromatous plaques.
Topics: Carotid Artery Diseases; Carotid Stenosis; Female; Humans; Isoquinolines; Male; Multimodal Imaging; | 2012 |
Increased peripheral benzodiazepine receptors in arterial plaque of patients with atherosclerosis: an autoradiographic study with [(3)H]PK 11195.
Topics: Aged; Aged, 80 and over; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Age | 2008 |