pk 11195 has been researched along with Brain Disorders in 8 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Banati, RB | 4 |
| Cagnin, A | 2 |
| Gerhard, A | 1 |
| Kassiou, M | 1 |
| Meikle, SR | 1 |
| Leong, DK | 1 |
| Le, O | 1 |
| Oliva, L | 1 |
| Butterworth, RF | 1 |
| Lallement, G | 1 |
| Delamanche, IS | 1 |
| Pernot-Marino, I | 1 |
| Baubichon, D | 1 |
| Denoyer, M | 1 |
| Carpentier, P | 1 |
| Blanchet, G | 1 |
| Levivier, M | 1 |
| Gash, DM | 1 |
| Przedborski, S | 1 |
| Chalon, S | 1 |
| Pellevoisin, C | 1 |
| Bodard, S | 1 |
| Vilar, MP | 1 |
| Besnard, JC | 1 |
| Guilloteau, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| PET Imaging of Peripheral Benzodiazepine Receptors in Patients With Carotid Atherosclerosis[NCT00547976] | Phase 1 | 5 participants (Actual) | Interventional | 2007-10-31 | Completed | ||
| Molecular Imaging Modality by Positron Emission Tomography Using 18F-X : Study of Microglial Activation in Amyotrophic Lateral Sclerosis[NCT00563537] | Phase 1 | 30 participants (Anticipated) | Interventional | 2007-01-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for pk 11195 and Brain Disorders
| Article | Year |
|---|---|
Visualising microglial activation in vivo.
Topics: Animals; Binding Sites; Brain Diseases; Carbon Radioisotopes; Encephalitis; Humans; Isoquinolines; L | 2002 |
Visualising microglial activation in vivo.
Topics: Animals; Binding Sites; Brain Diseases; Carbon Radioisotopes; Encephalitis; Humans; Isoquinolines; L | 2002 |
Visualising microglial activation in vivo.
Topics: Animals; Binding Sites; Brain Diseases; Carbon Radioisotopes; Encephalitis; Humans; Isoquinolines; L | 2002 |
Visualising microglial activation in vivo.
Topics: Animals; Binding Sites; Brain Diseases; Carbon Radioisotopes; Encephalitis; Humans; Isoquinolines; L | 2002 |
In vivo imaging of neuroinflammation.
Topics: Animals; Binding Sites; Brain; Brain Diseases; Carbon Radioisotopes; Humans; Inflammation; Isoquinol | 2002 |
Neuropathological imaging: in vivo detection of glial activation as a measure of disease and adaptive change in the brain.
Topics: Benzodiazepines; Binding Sites; Brain Diseases; Carbon Radioisotopes; Humans; Isoquinolines; Microgl | 2003 |
Positron emission tomography imaging of neuroinflammation.
Topics: Animals; Brain; Brain Diseases; Carbon Radioisotopes; Humans; Inflammation; Isoquinolines; Microglia | 2007 |
4 other studies available for pk 11195 and Brain Disorders
| Article | Year |
|---|---|
Increased densities of binding sites for the "peripheral-type" benzodiazepine receptor ligand [3H]PK11195 in vulnerable regions of the rat brain in thiamine deficiency encephalopathy.
Topics: Animals; Autoradiography; Binding Sites; Brain; Brain Diseases; Isoquinolines; Ligands; Male; Rats; | 1994 |
Neuroprotective activity of glutamate receptor antagonists against soman-induced hippocampal damage: quantification with an omega 3 site ligand.
Topics: Animals; Autoradiography; Benzoxazines; Brain; Brain Diseases; Excitatory Amino Acid Antagonists; Hi | 1993 |
Time course of the neuroprotective effect of transplantation on quinolinic acid-induced lesions of the striatum.
Topics: Adenosine; Animals; Autoradiography; Benzazepines; Brain Diseases; Corpus Striatum; Electron Transpo | 1995 |
Iodinated PK 11195 as an ex vivo marker of neuronal injury in the lesioned rat brain.
Topics: Animals; Autoradiography; Benzazepines; Brain; Brain Diseases; Disease Models, Animal; Iodine Radioi | 1996 |