pk 11195 has been researched along with Blood Poisoning in 1 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
Excerpt | Relevance | Reference |
---|---|---|
"Sepsis is an organ dysfunction caused by a host's unregulated response to infection, causing long-term brain dysfunction with microglial activation, the release of inflammatory components, and mitochondrial changes." | 1.62 | The Protective Effect of PK-11195 on Cognitive Impairment in Rats Survived of Polymicrobial Sepsis. ( Abatti, MR; Barichello, T; Dal-Pizzol, F; Dominguini, D; Generoso, JS; Steckert, AV, 2021) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (100.00) | 2.80 |
Authors | Studies |
---|---|
Dominguini, D | 1 |
Steckert, AV | 1 |
Abatti, MR | 1 |
Generoso, JS | 1 |
Barichello, T | 1 |
Dal-Pizzol, F | 1 |
1 other study available for pk 11195 and Blood Poisoning
Article | Year |
---|---|
The Protective Effect of PK-11195 on Cognitive Impairment in Rats Survived of Polymicrobial Sepsis.
Topics: Animals; Brain; Cognitive Dysfunction; Cytokines; Isoquinolines; Male; Microglia; Neuroprotective Ag | 2021 |