pk 11195 has been researched along with B-Cell Chronic Lymphocytic Leukemia in 2 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
| Excerpt | Relevance | Reference |
|---|---|---|
| "Despite the high incidence of chronic lymphocytic leukemia (CLL), metabolism of CLL cells remains a relatively unexplored area." | 1.40 | Mitochondrial metabolism contributes to oxidative stress and reveals therapeutic targets in chronic lymphocytic leukemia. ( Berger, J; Bricks, J; Bruns, H; Eckart, MJ; Giessl, A; Hofmann, AD; Jitschin, R; Mackensen, A; Mougiakakos, D; Saul, D, 2014) |
| "Primary chronic lymphocytic leukemia (CLL) cells overexpress TSPO." | 1.34 | The potential anticancer agent PK11195 induces apoptosis irrespective of p53 and ATM status in chronic lymphocytic leukemia cells. ( Campàs, C; Coll-Mulet, L; Cosialls, AM; de Frias, M; Domingo, A; Gil, J; González-Gironès, DM; Iglesias-Serret, D; Pons, G; Santidrián, AF, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jitschin, R | 1 |
| Hofmann, AD | 1 |
| Bruns, H | 1 |
| Giessl, A | 1 |
| Bricks, J | 1 |
| Berger, J | 1 |
| Saul, D | 1 |
| Eckart, MJ | 1 |
| Mackensen, A | 1 |
| Mougiakakos, D | 1 |
| Santidrián, AF | 1 |
| Cosialls, AM | 1 |
| Coll-Mulet, L | 1 |
| Iglesias-Serret, D | 1 |
| de Frias, M | 1 |
| González-Gironès, DM | 1 |
| Campàs, C | 1 |
| Domingo, A | 1 |
| Pons, G | 1 |
| Gil, J | 1 |
2 other studies available for pk 11195 and B-Cell Chronic Lymphocytic Leukemia
| Article | Year |
|---|---|
Mitochondrial metabolism contributes to oxidative stress and reveals therapeutic targets in chronic lymphocytic leukemia.
Topics: Adenosine Triphosphatases; Aged; Aged, 80 and over; Antineoplastic Agents; Antioxidants; Cell Separa | 2014 |
The potential anticancer agent PK11195 induces apoptosis irrespective of p53 and ATM status in chronic lymphocytic leukemia cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adult; Aged; Aged, 80 and over; Antineoplastic Age | 2007 |