pk 11195 has been researched along with Atherogenesis in 4 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
| Excerpt | Relevance | Reference |
|---|---|---|
| "Six patients diagnosed as carotid atherosclerosis underwent endarterectomy." | 5.35 | Increased peripheral benzodiazepine receptors in arterial plaque of patients with atherosclerosis: an autoradiographic study with [(3)H]PK 11195. ( Fujimura, Y; Fujita, M; Hwang, PM; Imaizumi, M; Innis, RB; Kozloff, L; Trout Iii, H, 2008) |
| "From the nascent atherosclerotic plaque to the death of inflammatory cells, several potential molecular and micro-anatomical targets for imaging with particular selective imaging probes and with a variety of imaging modalities have emerged from preclinical and animal investigations." | 2.48 | Non-invasive anatomic and functional imaging of vascular inflammation and unstable plaque. ( Camici, PG; Gaemperli, O; Libby, P; Rimoldi, OE, 2012) |
| "Six patients diagnosed as carotid atherosclerosis underwent endarterectomy." | 1.35 | Increased peripheral benzodiazepine receptors in arterial plaque of patients with atherosclerosis: an autoradiographic study with [(3)H]PK 11195. ( Fujimura, Y; Fujita, M; Hwang, PM; Imaizumi, M; Innis, RB; Kozloff, L; Trout Iii, H, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Laitinen, I | 1 |
| Marjamäki, P | 1 |
| Någren, K | 1 |
| Laine, VJ | 1 |
| Wilson, I | 1 |
| Leppänen, P | 1 |
| Ylä-Herttuala, S | 1 |
| Roivainen, A | 1 |
| Knuuti, J | 1 |
| Bird, JL | 1 |
| Izquierdo-Garcia, D | 1 |
| Davies, JR | 1 |
| Rudd, JH | 1 |
| Probst, KC | 1 |
| Figg, N | 1 |
| Clark, JC | 1 |
| Weissberg, PL | 1 |
| Davenport, AP | 1 |
| Warburton, EA | 1 |
| Camici, PG | 1 |
| Rimoldi, OE | 1 |
| Gaemperli, O | 1 |
| Libby, P | 1 |
| Fujimura, Y | 1 |
| Hwang, PM | 1 |
| Trout Iii, H | 1 |
| Kozloff, L | 1 |
| Imaizumi, M | 1 |
| Innis, RB | 1 |
| Fujita, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| In Vivo Molecular Imaging (MRI) of Atherothrombotic Lesions[NCT01418313] | 886 participants (Actual) | Observational | 2011-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pk 11195 and Atherogenesis
| Article | Year |
|---|---|
Non-invasive anatomic and functional imaging of vascular inflammation and unstable plaque.
Topics: Animals; Atherosclerosis; Contrast Media; Diagnostic Imaging; Fluorodeoxyglucose F18; Hemorrhage; Hu | 2012 |
3 other studies available for pk 11195 and Atherogenesis
| Article | Year |
|---|---|
Uptake of inflammatory cell marker [11C]PK11195 into mouse atherosclerotic plaques.
Topics: Animals; Aorta; Atherosclerosis; Autoradiography; Biomarkers; Carbon Radioisotopes; Feasibility Stud | 2009 |
Evaluation of translocator protein quantification as a tool for characterising macrophage burden in human carotid atherosclerosis.
Topics: Aged; Atherosclerosis; Carotid Arteries; Carotid Artery Diseases; Constriction, Pathologic; Female; | 2010 |
Increased peripheral benzodiazepine receptors in arterial plaque of patients with atherosclerosis: an autoradiographic study with [(3)H]PK 11195.
Topics: Aged; Aged, 80 and over; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Age | 2008 |