pk 11195 has been researched along with Angiitis in 4 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
| Excerpt | Relevance | Reference |
|---|---|---|
| "Such focal brain inflammation aggravates secondary brain injury by exacerbating blood-brain barrier damage, microvascular failure, brain oedema, oxidative stress, and by directly inducing neuronal cell death." | 2.61 | Global brain inflammation in stroke. ( Ducruet, AF; Lawton, MT; Li, ZG; Shi, FD; Shi, K; Tian, DC, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shi, K | 1 |
| Tian, DC | 1 |
| Li, ZG | 1 |
| Ducruet, AF | 1 |
| Lawton, MT | 1 |
| Shi, FD | 1 |
| Pugliese, F | 2 |
| Gaemperli, O | 2 |
| Kinderlerer, AR | 1 |
| Lamare, F | 2 |
| Shalhoub, J | 1 |
| Davies, AH | 1 |
| Rimoldi, OE | 2 |
| Mason, JC | 2 |
| Camici, PG | 2 |
| Hinz, R | 1 |
| Spinks, T | 1 |
| Goerres, GW | 1 |
| Revesz, T | 1 |
| Duncan, J | 1 |
| Banati, RB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Minocycline in Patients With Moderate to Severe Acute Ischemic Stroke: A Prospective, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Phase III Trial[NCT05836740] | Phase 3 | 1,672 participants (Anticipated) | Interventional | 2023-05-19 | Recruiting | ||
| Efficacy and Safety of Sarecycline in Patients With Acute Ischemic Stroke After Reperfusion Therapy: A Phase II, Randomized, Multicenter, Double-blind, Single Dose, Placebo-controlled Parallel Trial[NCT05836753] | Phase 2 | 120 participants (Anticipated) | Interventional | 2023-05-07 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pk 11195 and Angiitis
| Article | Year |
|---|---|
Global brain inflammation in stroke.
Topics: Animals; Brain Damage, Chronic; Brain Ischemia; Cerebral Hemorrhage; Encephalitis; Forecasting; Huma | 2019 |
Global brain inflammation in stroke.
Topics: Animals; Brain Damage, Chronic; Brain Ischemia; Cerebral Hemorrhage; Encephalitis; Forecasting; Huma | 2019 |
Global brain inflammation in stroke.
Topics: Animals; Brain Damage, Chronic; Brain Ischemia; Cerebral Hemorrhage; Encephalitis; Forecasting; Huma | 2019 |
Global brain inflammation in stroke.
Topics: Animals; Brain Damage, Chronic; Brain Ischemia; Cerebral Hemorrhage; Encephalitis; Forecasting; Huma | 2019 |
3 other studies available for pk 11195 and Angiitis
| Article | Year |
|---|---|
Imaging of vascular inflammation with [11C]-PK11195 and positron emission tomography/computed tomography angiography.
Topics: Adult; Aged; Angiography; Arteries; Carbon Radioisotopes; Female; Giant Cell Arteritis; Humans; Imag | 2010 |
Detection and quantification of large-vessel inflammation with 11C-(R)-PK11195 PET/CT.
Topics: Adult; Aged; Carbon Radioisotopes; Humans; Isoquinolines; Middle Aged; Positron-Emission Tomography; | 2011 |
Imaging cerebral vasculitis in refractory epilepsy using [(11)C](R)-PK11195 positron emission tomography.
Topics: Adult; Carbon Radioisotopes; Cerebrovascular Disorders; Diagnosis, Differential; Dominance, Cerebral | 2001 |