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pk 11195 and Anesthesia

pk 11195 has been researched along with Anesthesia in 3 studies

PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
" Oral administration of DAA1106, diazepam and buspirone but not DAA1097 significantly increased sleeping time in hexobarbital-induced anesthesia in mice."3.70Neuropharmacological profile of peripheral benzodiazepine receptor agonists, DAA1097 and DAA1106. ( Chaki, S; Nagamine, M; Nakazato, A; Ogawa, S; Okubo, T; Okuyama, S; Suzuki, Y; Tomisawa, K; Yoshikawa, R, 1999)
"Clonazepam did not produce anaesthesia, at doses up to 1 g kg-1 or when given with nitrendipine."1.28Differential interactions between benzodiazepines and the dihydropyridines, nitrendipine and Bay K 8644. ( Dolin, SJ; Little, HJ; Patch, TL; Rabbani, M; Taberner, PV, 1991)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Okuyama, S1
Chaki, S1
Yoshikawa, R1
Ogawa, S1
Suzuki, Y1
Okubo, T1
Nakazato, A1
Nagamine, M1
Tomisawa, K1
Dolin, SJ1
Patch, TL1
Rabbani, M1
Taberner, PV1
Little, HJ1
Albertson, TE1
Joy, RM1

Other Studies

3 other studies available for pk 11195 and Anesthesia

ArticleYear
Neuropharmacological profile of peripheral benzodiazepine receptor agonists, DAA1097 and DAA1106.
    Life sciences, 1999, Volume: 64, Issue:16

    Topics: Acetamides; Anesthesia; Animals; Anti-Anxiety Agents; Benzodiazepinones; Brain; Buspirone; Cell Memb

1999
Differential interactions between benzodiazepines and the dihydropyridines, nitrendipine and Bay K 8644.
    Neuropharmacology, 1991, Volume: 30, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Modification of evoked hippocampal dentate inhibition by diazepam and three antagonists in urethane-anesthetized rats.
    Experimental neurology, 1989, Volume: 106, Issue:2

    Topics: Anesthesia; Animals; Diazepam; Evoked Potentials; Flumazenil; gamma-Aminobutyric Acid; Hippocampus;

1989