pk 11195 has been researched along with Anesthesia in 3 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Oral administration of DAA1106, diazepam and buspirone but not DAA1097 significantly increased sleeping time in hexobarbital-induced anesthesia in mice." | 3.70 | Neuropharmacological profile of peripheral benzodiazepine receptor agonists, DAA1097 and DAA1106. ( Chaki, S; Nagamine, M; Nakazato, A; Ogawa, S; Okubo, T; Okuyama, S; Suzuki, Y; Tomisawa, K; Yoshikawa, R, 1999) |
| "Clonazepam did not produce anaesthesia, at doses up to 1 g kg-1 or when given with nitrendipine." | 1.28 | Differential interactions between benzodiazepines and the dihydropyridines, nitrendipine and Bay K 8644. ( Dolin, SJ; Little, HJ; Patch, TL; Rabbani, M; Taberner, PV, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Okuyama, S | 1 |
| Chaki, S | 1 |
| Yoshikawa, R | 1 |
| Ogawa, S | 1 |
| Suzuki, Y | 1 |
| Okubo, T | 1 |
| Nakazato, A | 1 |
| Nagamine, M | 1 |
| Tomisawa, K | 1 |
| Dolin, SJ | 1 |
| Patch, TL | 1 |
| Rabbani, M | 1 |
| Taberner, PV | 1 |
| Little, HJ | 1 |
| Albertson, TE | 1 |
| Joy, RM | 1 |
3 other studies available for pk 11195 and Anesthesia
| Article | Year |
|---|---|
Neuropharmacological profile of peripheral benzodiazepine receptor agonists, DAA1097 and DAA1106.
Topics: Acetamides; Anesthesia; Animals; Anti-Anxiety Agents; Benzodiazepinones; Brain; Buspirone; Cell Memb | 1999 |
Differential interactions between benzodiazepines and the dihydropyridines, nitrendipine and Bay K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |
Modification of evoked hippocampal dentate inhibition by diazepam and three antagonists in urethane-anesthetized rats.
Topics: Anesthesia; Animals; Diazepam; Evoked Potentials; Flumazenil; gamma-Aminobutyric Acid; Hippocampus; | 1989 |