pk 11195 has been researched along with Allergic Encephalomyelitis in 4 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abourbeh, G | 1 |
| Thézé, B | 1 |
| Maroy, R | 1 |
| Dubois, A | 1 |
| Brulon, V | 1 |
| Fontyn, Y | 1 |
| Dollé, F | 1 |
| Tavitian, B | 1 |
| Boisgard, R | 1 |
| Vowinckel, E | 1 |
| Reutens, D | 1 |
| Becher, B | 1 |
| Verge, G | 1 |
| Evans, A | 1 |
| Owens, T | 1 |
| Antel, JP | 1 |
| Agnello, D | 1 |
| Carvelli, L | 1 |
| Muzio, V | 1 |
| Villa, P | 1 |
| Bottazzi, B | 1 |
| Polentarutti, N | 1 |
| Mennini, T | 1 |
| Mantovani, A | 1 |
| Ghezzi, P | 1 |
| Banati, RB | 1 |
| Newcombe, J | 1 |
| Gunn, RN | 1 |
| Cagnin, A | 1 |
| Turkheimer, F | 1 |
| Heppner, F | 1 |
| Price, G | 1 |
| Wegner, F | 1 |
| Giovannoni, G | 1 |
| Miller, DH | 1 |
| Perkin, GD | 1 |
| Smith, T | 1 |
| Hewson, AK | 1 |
| Bydder, G | 1 |
| Kreutzberg, GW | 1 |
| Jones, T | 1 |
| Cuzner, ML | 1 |
| Myers, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Brain Inflammation In Major Depressive Disorder[NCT01851356] | 61 participants (Actual) | Observational | 2013-05-08 | Completed | |||
| Assessment of [11C]ER-176 to Image Translocator Protein in Brain and Whole-Body of Healthy Subjects[NCT02147392] | Early Phase 1 | 16 participants (Actual) | Interventional | 2014-05-14 | Completed | ||
| Assessment of [11C]DPA-713 in Temporal Lobe Epilepsy[NCT01793532] | 38 participants (Actual) | Observational | 2013-01-31 | Completed | |||
| Molecular Imaging Modality by Positron Emission Tomography Using 18F-X : Study of Microglial Activation in Amyotrophic Lateral Sclerosis[NCT00563537] | Phase 1 | 30 participants (Anticipated) | Interventional | 2007-01-31 | Recruiting | ||
| PET Imaging of Peripheral Benzodiazepine Receptors Using [11C](R)-PK 11195 and [11C]PBR28[NCT00696371] | 15 participants (Actual) | Observational | 2008-06-06 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for pk 11195 and Allergic Encephalomyelitis
| Article | Year |
|---|---|
Imaging microglial/macrophage activation in spinal cords of experimental autoimmune encephalomyelitis rats by positron emission tomography using the mitochondrial 18 kDa translocator protein radioligand [¹⁸F]DPA-714.
Topics: Animals; Antigens, CD; Carrier Proteins; Disease Models, Animal; Encephalomyelitis, Autoimmune, Expe | 2012 |
PK11195 binding to the peripheral benzodiazepine receptor as a marker of microglia activation in multiple sclerosis and experimental autoimmune encephalomyelitis.
Topics: Animals; Biomarkers; Brain; Encephalomyelitis, Autoimmune, Experimental; Humans; Isoquinolines; Magn | 1997 |
Increased peripheral benzodiazepine binding sites and pentraxin 3 expression in the spinal cord during EAE: relation to inflammatory cytokines and modulation by dexamethasone and rolipram.
Topics: Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; C-Reactive Protein; Dexamethasone; E | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity.
Topics: Adult; Animals; Antineoplastic Agents; Benzodiazepines; Binding Sites; Brain; Carbon Radioisotopes; | 2000 |