pk 11195 has been researched along with Alcohol Abuse in 4 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of chronic alcoholism and detoxification treatment with disulfiram on platelet peripheral benzodiazepine receptors was studied in alcoholic males." | 3.68 | Peripheral benzodiazepine receptors on platelets in chronic and detoxified alcoholics. ( Fliman, M; Gavish, M; Karp, L; Tyano, S; Weizman, A, 1991) |
| "Alcohol abuse is the cause of many liver diseases, such as steatosis, alcoholic steatohepatitis, fibrosis, cirrhosis, and, potentially, hepatocellular cancer." | 1.56 | The Effects of PK11195 and Protoporphyrin IX Can Modulate Chronic Alcohol Intoxication in Rat Liver Mitochondria under the Opening of the Mitochondrial Permeability Transition Pore. ( Baburina, Y; Krestinina, O; Odinokova, I, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baburina, Y | 1 |
| Odinokova, I | 1 |
| Krestinina, O | 1 |
| Wong, PT | 1 |
| Tan, CH | 1 |
| Kwan, MF | 1 |
| Ang, LK | 1 |
| Teo, WL | 1 |
| Karp, L | 1 |
| Weizman, A | 1 |
| Fliman, M | 1 |
| Tyano, S | 1 |
| Gavish, M | 1 |
| Suranyi-Cadotte, B | 1 |
| Lafaille, F | 1 |
| Dongier, M | 1 |
| Dumas, M | 1 |
| Quirion, R | 1 |
4 other studies available for pk 11195 and Alcohol Abuse
| Article | Year |
|---|---|
The Effects of PK11195 and Protoporphyrin IX Can Modulate Chronic Alcohol Intoxication in Rat Liver Mitochondria under the Opening of the Mitochondrial Permeability Transition Pore.
Topics: Alcoholism; Animals; Antineoplastic Agents; Humans; Isoquinolines; Mitochondria, Liver; Mitochondria | 2020 |
Effects of ethanol on peripheral benzodiazepine binding sites in the mouse cerebellum and brain stem.
Topics: Alcoholism; Animals; Benzodiazepines; Body Weight; Brain Stem; Cerebellum; Disease Models, Animal; D | 1995 |
Peripheral benzodiazepine receptors on platelets in chronic and detoxified alcoholics.
Topics: Adult; Alcoholism; Blood Platelets; Cell Membrane; Disulfiram; Humans; Isoquinolines; Male; Middle A | 1991 |
Decreased density of peripheral benzodiazepine binding sites on platelets of currently drinking, but not abstinent alcoholics.
Topics: Adult; Alcohol Drinking; Alcoholism; Binding Sites; Blood Platelets; Female; Humans; Isoquinolines; | 1988 |