pk 11195 has been researched along with Akinetic-Rigid Variant of Huntington Disease in 10 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have studied 9 symptomatic Huntington's disease patients (age = 46." | 1.35 | Hypothalamic involvement in Huntington's disease: an in vivo PET study. ( Barker, RA; Pavese, N; Piccini, P; Politis, M; Tabrizi, SJ; Tai, YF, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 7 (70.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grecchi, E | 1 |
| Doyle, OM | 1 |
| Bertoldo, A | 2 |
| Pavese, N | 7 |
| Turkheimer, FE | 4 |
| Politis, M | 1 |
| Tai, YF | 6 |
| Tabrizi, SJ | 3 |
| Barker, RA | 3 |
| Piccini, P | 3 |
| Tomasi, G | 1 |
| Cobelli, C | 1 |
| Hammers, A | 3 |
| Ryu, JK | 1 |
| Choi, HB | 1 |
| McLarnon, JG | 1 |
| Edison, P | 2 |
| Roncaroli, F | 1 |
| Anderson, AN | 2 |
| Gerhard, A | 4 |
| Hinz, R | 1 |
| Brooks, DJ | 4 |
| Levivier, M | 1 |
| Przedborski, S | 1 |
| Gouhier, C | 1 |
| Chalon, S | 1 |
| Venier-Julienne, MC | 1 |
| Bodard, S | 1 |
| Benoit, J | 1 |
| Besnard, J | 1 |
| Guilloteau, D | 1 |
1 review available for pk 11195 and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Imaging microglial activation in Huntington's disease.
Topics: Animals; Brain; Carbon Radioisotopes; Humans; Huntington Disease; Isoquinolines; Microglia; Positron | 2007 |
9 other studies available for pk 11195 and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Brain shaving: adaptive detection for brain PET data.
Topics: Brain; Carbon Radioisotopes; Case-Control Studies; Humans; Huntington Disease; Image Processing, Com | 2014 |
Hypothalamic involvement in Huntington's disease: an in vivo PET study.
Topics: Adult; Brain Mapping; Carbon Radioisotopes; Female; Heterozygote; Humans; Huntington Disease; Hypoth | 2008 |
Global-two-stage filtering of clinical PET parametric maps: application to [(11)C]-(R)-PK11195.
Topics: Adult; Algorithms; Arterioles; Bayes Theorem; Brain; Brain Mapping; Cerebral Arteries; Cerebral Vein | 2011 |
Peripheral benzodiazepine receptor ligand PK11195 reduces microglial activation and neuronal death in quinolinic acid-injected rat striatum.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Antineoplastic Agents; Carrier Proteins; Caspases; | 2005 |
Reference and target region modeling of [11C]-(R)-PK11195 brain studies.
Topics: Algorithms; Antineoplastic Agents; Brain; Carbon Radioisotopes; Case-Control Studies; Cluster Analys | 2007 |
A systematic comparison of kinetic modelling methods generating parametric maps for [(11)C]-(R)-PK11195.
Topics: Alzheimer Disease; Brain; Brain Mapping; Carbon Radioisotopes; Cluster Analysis; Computer Graphics; | 2007 |
Microglial activation in presymptomatic Huntington's disease gene carriers.
Topics: Adult; Brain Mapping; Carbon Radioisotopes; Cerebral Cortex; Corpus Striatum; Disease Progression; F | 2007 |
Quinolinic acid-induced lesions of the rat striatum: quantitative autoradiographic binding assessment.
Topics: Animals; Autoradiography; Benzazepines; Binding, Competitive; Cholinergic Agents; Corpus Striatum; D | 1998 |
Neuroprotection of nerve growth factor-loaded microspheres on the D2 dopaminergic receptor positive-striatal neurones in quinolinic acid-lesioned rats: a quantitative autoradiographic assessment with iodobenzamide.
Topics: Animals; Antineoplastic Agents; Autoradiography; Benzamides; Biocompatible Materials; Corpus Striatu | 2000 |