pk 11195 has been researched along with Acute Necrotizing Encephalitis, Herpetic in 3 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
| Excerpt | Relevance | Reference |
|---|---|---|
| " Despite its use in clinical research, no studies on the imaging properties and pharmacokinetic analysis of (11)C-PBR28 in rodent models of neuroinflammation have been published yet." | 1.43 | Pharmacokinetic Analysis of 11C-PBR28 in the Rat Model of Herpes Encephalitis: Comparison with (R)-11C-PK11195. ( de Vries, EF; Dierckx, RA; Doorduin, J; Feltes, PK; Moriguchi Jeckel, CM; Parente, A; Sijbesma, JW; Vállez García, D, 2016) |
| "Two patients with asymmetrical herpes simplex encephalitis were serially scanned 6 and 12 months after the acute illness using PET with [11C] (R)-PK11195, a marker of activated microglia/brain macrophages." | 1.31 | In vivo visualization of activated glia by [11C] (R)-PK11195-PET following herpes encephalitis reveals projected neuronal damage beyond the primary focal lesion. ( Banati, RB; Cagnin, A; Gunn, RN; Jones, T; Kreutzberg, GW; Lawrence, AD; Myers, R; Stevens, T, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Parente, A | 1 |
| Feltes, PK | 1 |
| Vállez García, D | 1 |
| Sijbesma, JW | 1 |
| Moriguchi Jeckel, CM | 1 |
| Dierckx, RA | 2 |
| de Vries, EF | 2 |
| Doorduin, J | 2 |
| Antunes, IF | 1 |
| Haisma, HJ | 1 |
| Elsinga, PH | 1 |
| van Waarde, A | 1 |
| Willemsen, AT | 1 |
| Cagnin, A | 1 |
| Myers, R | 1 |
| Gunn, RN | 1 |
| Lawrence, AD | 1 |
| Stevens, T | 1 |
| Kreutzberg, GW | 1 |
| Jones, T | 1 |
| Banati, RB | 1 |
3 other studies available for pk 11195 and Acute Necrotizing Encephalitis, Herpetic
| Article | Year |
|---|---|
Pharmacokinetic Analysis of 11C-PBR28 in the Rat Model of Herpes Encephalitis: Comparison with (R)-11C-PK11195.
Topics: Animals; Biological Transport; Disease Models, Animal; Encephalitis, Herpes Simplex; Image Processin | 2016 |
18F-FEAnGA for PET of β-glucuronidase activity in neuroinflammation.
Topics: Animals; Benzyl Alcohols; Biotransformation; Brain; Encephalitis, Herpes Simplex; Glucuronates; Gluc | 2012 |
In vivo visualization of activated glia by [11C] (R)-PK11195-PET following herpes encephalitis reveals projected neuronal damage beyond the primary focal lesion.
Topics: Adult; Aged; Aged, 80 and over; Binding Sites; Brain; Carbon Radioisotopes; Chi-Square Distribution; | 2001 |