pk 11195 has been researched along with AIDS Dementia Complex in 2 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
AIDS Dementia Complex: A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hammoud, DA | 1 |
| Endres, CJ | 1 |
| Chander, AR | 1 |
| Guilarte, TR | 1 |
| Wong, DF | 1 |
| Sacktor, NC | 1 |
| McArthur, JC | 1 |
| Pomper, MG | 1 |
| Wiley, CA | 1 |
| Lopresti, BJ | 1 |
| Becker, JT | 1 |
| Boada, F | 1 |
| Lopez, OL | 1 |
| Mellors, J | 1 |
| Meltzer, CC | 1 |
| Wisniewski, SR | 1 |
| Mathis, CA | 1 |
1 trial available for pk 11195 and AIDS Dementia Complex
| Article | Year |
|---|---|
Imaging glial cell activation with [11C]-R-PK11195 in patients with AIDS.
Topics: Adult; AIDS Dementia Complex; Antineoplastic Agents; Brain; Carbon Radioisotopes; Female; Humans; Is | 2005 |
1 other study available for pk 11195 and AIDS Dementia Complex
| Article | Year |
|---|---|
Positron emission tomography imaging of peripheral benzodiazepine receptor binding in human immunodeficiency virus-infected subjects with and without cognitive impairment.
Topics: Adult; Aged; AIDS Dementia Complex; Brain; Carbon Radioisotopes; HIV; HIV Infections; Humans; Isoqui | 2006 |