pj-34 has been researched along with Injury, Myocardial Reperfusion in 1 studies
PJ34 : A member of the class of phenanthridines that is 5,6-dihydrophenanthridine substituted at positions 2 and 6 by (N,N-dimethylglycyl)amino and oxo groups, respectively. It is a potent inhibitor of poly(ADP-ribose) polymerases PARP1 and PARP2 (IC50 of 110 nM and 86 nM, respectively) and exhibits anti-cancer, cardioprotective and neuroprotective properties.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eltze, T | 1 |
| Boer, R | 1 |
| Wagner, T | 1 |
| Weinbrenner, S | 1 |
| McDonald, MC | 1 |
| Thiemermann, C | 1 |
| Bürkle, A | 1 |
| Klein, T | 1 |
1 other study available for pj-34 and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Imidazoquinolinone, imidazopyridine, and isoquinolindione derivatives as novel and potent inhibitors of the poly(ADP-ribose) polymerase (PARP): a comparison with standard PARP inhibitors.
Topics: Animals; Cell Line; Cell Line, Tumor; Fibroblasts; Humans; Imidazoles; Isoquinolines; Kinetics; Male | 2008 |